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The map label for this gene is nrdR

Identifier: 16272880

GI number: 16272880

Start: 1002915

End: 1003364

Strand: Direct

Name: nrdR

Synonym: HI0943

Alternate gene names: 16272880

Gene position: 1002915-1003364 (Clockwise)

Preceding gene: 16272879

Following gene: 16272881

Centisome position: 54.8

GC content: 36.22

Gene sequence:

>450_bases
ATGCACTGTCCATTTTGTGATACAGAAGAAACTAAAGTCATTGATAGCCGTTTAGTATCTGATGGTTATCAAGTTCGCCG
CCGCCGTGAGTGCGGTCATTGTCATGAACGTTTTACTACTTTTGAAATGGCGGAATTAATCATACCGAAAATTATCAAAA
CTGATGGTACACGTGAGCCATTCAATGAAGATAAATTGCGCAGCGGTATTCAACACGCCTTAGAAAAACGTCCTGTAAGT
GCAGATGATGTAGAAAAAGCAATTAATCACATAATTCTTCAACTGCGTGCAACTGGAGAACGTGAAGTGCCAAGTAAGTT
AGTGGGTAAACTTGCGATGAATGAATTAAAAAAACTCGATAAAGTGGCTTATATTCGTTTTGCATCAGTCTATTTAAGTT
TTGATGATATTGATCAATTTACTATCGAAATTGAAAAATTAAAGGATTAA

Upstream 100 bases:

>100_bases
TGGCTTATTATTCGCACAAAAGAAGACAAGAAAGACACAAAGCTAATCGTCAAATAACCTATTTTTTAGTAGAATAACAC
CCTTTTATGGAGAATTATCT

Downstream 100 bases:

>100_bases
TTATGCTTGAATTTTCCTCACAAGATTGCGTATTTATGCAACGTGCCTTAGATTTGGCAGCCAAAGGTCAATATACCACT
ACACCGAACCCATCGGTGGG

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MHCPFCDTEETKVIDSRLVSDGYQVRRRRECGHCHERFTTFEMAELIIPKIIKTDGTREPFNEDKLRSGIQHALEKRPVS
ADDVEKAINHIILQLRATGEREVPSKLVGKLAMNELKKLDKVAYIRFASVYLSFDDIDQFTIEIEKLKD

Sequences:

>Translated_149_residues
MHCPFCDTEETKVIDSRLVSDGYQVRRRRECGHCHERFTTFEMAELIIPKIIKTDGTREPFNEDKLRSGIQHALEKRPVS
ADDVEKAINHIILQLRATGEREVPSKLVGKLAMNELKKLDKVAYIRFASVYLSFDDIDQFTIEIEKLKD
>Mature_149_residues
MHCPFCDTEETKVIDSRLVSDGYQVRRRRECGHCHERFTTFEMAELIIPKIIKTDGTREPFNEDKLRSGIQHALEKRPVS
ADDVEKAINHIILQLRATGEREVPSKLVGKLAMNELKKLDKVAYIRFASVYLSFDDIDQFTIEIEKLKD

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=149, Percent_Identity=69.7986577181208, Blast_Score=220, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_HAEI8 (Q4QLW5)

Other databases:

- EMBL:   CP000057
- RefSeq:   YP_248642.1
- STRING:   Q4QLW5
- GeneID:   3430407
- GenomeReviews:   CP000057_GR
- KEGG:   hit:NTHI1114
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- PhylomeDB:   Q4QLW5
- ProtClustDB:   PRK00464
- BioCyc:   HINF281310:NTHI1114-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17279; Mature: 17279

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHCPFCDTEETKVIDSRLVSDGYQVRRRRECGHCHERFTTFEMAELIIPKIIKTDGTREP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
FNEDKLRSGIQHALEKRPVSADDVEKAINHIILQLRATGEREVPSKLVGKLAMNELKKLD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
KVAYIRFASVYLSFDDIDQFTIEIEKLKD
HHHHHHHHHHHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MHCPFCDTEETKVIDSRLVSDGYQVRRRRECGHCHERFTTFEMAELIIPKIIKTDGTREP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
FNEDKLRSGIQHALEKRPVSADDVEKAINHIILQLRATGEREVPSKLVGKLAMNELKKLD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
KVAYIRFASVYLSFDDIDQFTIEIEKLKD
HHHHHHHHHHHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA