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The map label for this gene is arcA

Identifier: 16272824

GI number: 16272824

Start: 936511

End: 937221

Strand: Reverse

Name: arcA

Synonym: HI0884

Alternate gene names: 16272824

Gene position: 937221-936511 (Counterclockwise)

Preceding gene: 16272835

Following gene: 16272823

Centisome position: 51.21

GC content: 36.01

Gene sequence:

>711_bases
ATGACTACTCCAAAAATTCTCGTTGTTGAAGATGAAATTGTCACTCGAAATACGCTTAAAGGGATTTTTGAAGCGGAAGG
ATATGATGTGTTTGAAGCAGAAAATGGTGTTGAAATGCATCATATATTGGCAAATCATAATATTAATTTGGTTGTGATGG
ATATTAATTTACCAGGCAAAAACGGCTTATTATTGGCAAGAGAACTCCGTGAAGAATTAAGCTTACCTCTTATTTTTTTA
ACTGGTCGAGATAATGAAGTGGATAAAATTTTAGGTTTGGAAATTGGTGCCGATGACTATTTGACTAAGCCTTTTAACCC
TAGAGAACTGACTATCCGCGCACGTAATCTATTGCATCGTGCAATGCCGCATCAAGAAAAAGAAAATACATTTGGTCGAG
AATTCTATCGTTTTAATGGTTGGAAATTAGACCTAAATAGCCACAGTTTAATTACACCAGAAGGACAAGAATTCAAACTT
CCTCGCAGTGAATTTCGTGCAATGTTACATTTCTGTGAAAATCCAGGAAAATTGCAAACGCGCGAAGAATTGCTGAAAAA
AATGACCGGACGAGAGTTAAAACCTCAGGATCGTACCGTAGATGTCACAATTCGACGTATCAGAAAACATTTTGAAGATC
ATCCCAATACTCCAAATATCATTATGACTATACATGGAGAAGGCTATCGTTTTTGTGGAGATATTGAATAA

Upstream 100 bases:

>100_bases
CAGGTAAAAAATCACCGCACTTTTTTATTGTTACAATAATGTTGCACAGATAGAATGATAGCTTTGATAGCATACGCCAA
AATAAGTATAAGGATGGAAA

Downstream 100 bases:

>100_bases
AGTGATTGTTCTACATAAAAATTCCTTTTTGAAATTCATTTCCTGTTTTGTTAGAATTCGCACACTTTTCAATATCTAAT
GGAAAGTGAGTTCGGATGAA

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MTTPKILVVEDEIVTRNTLKGIFEAEGYDVFEAENGVEMHHILANHNINLVVMDINLPGKNGLLLARELREELSLPLIFL
TGRDNEVDKILGLEIGADDYLTKPFNPRELTIRARNLLHRAMPHQEKENTFGREFYRFNGWKLDLNSHSLITPEGQEFKL
PRSEFRAMLHFCENPGKLQTREELLKKMTGRELKPQDRTVDVTIRRIRKHFEDHPNTPNIIMTIHGEGYRFCGDIE

Sequences:

>Translated_236_residues
MTTPKILVVEDEIVTRNTLKGIFEAEGYDVFEAENGVEMHHILANHNINLVVMDINLPGKNGLLLARELREELSLPLIFL
TGRDNEVDKILGLEIGADDYLTKPFNPRELTIRARNLLHRAMPHQEKENTFGREFYRFNGWKLDLNSHSLITPEGQEFKL
PRSEFRAMLHFCENPGKLQTREELLKKMTGRELKPQDRTVDVTIRRIRKHFEDHPNTPNIIMTIHGEGYRFCGDIE
>Mature_235_residues
TTPKILVVEDEIVTRNTLKGIFEAEGYDVFEAENGVEMHHILANHNINLVVMDINLPGKNGLLLARELREELSLPLIFLT
GRDNEVDKILGLEIGADDYLTKPFNPRELTIRARNLLHRAMPHQEKENTFGREFYRFNGWKLDLNSHSLITPEGQEFKLP
RSEFRAMLHFCENPGKLQTREELLKKMTGRELKPQDRTVDVTIRRIRKHFEDHPNTPNIIMTIHGEGYRFCGDIE

Specific function: Member of the two-component regulatory system ArcB/ArcA. Represses a wide variety of aerobic enzymes under anaerobic conditions

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain

Homologues:

Organism=Escherichia coli, GI1790863, Length=237, Percent_Identity=77.2151898734177, Blast_Score=379, Evalue=1e-107,
Organism=Escherichia coli, GI1787229, Length=237, Percent_Identity=40.9282700421941, Blast_Score=186, Evalue=1e-48,
Organism=Escherichia coli, GI1789809, Length=237, Percent_Identity=35.8649789029536, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786599, Length=231, Percent_Identity=34.6320346320346, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1788394, Length=238, Percent_Identity=31.9327731092437, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=34.5132743362832, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=32.5991189427313, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI87082012, Length=230, Percent_Identity=32.1739130434783, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1790860, Length=234, Percent_Identity=31.6239316239316, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=30.1310043668122, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=31.7180616740088, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=27.7777777777778, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1790552, Length=234, Percent_Identity=31.6239316239316, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=26.9911504424779, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1788550, Length=122, Percent_Identity=31.9672131147541, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): ARCA_HAEIN (P44918)

Other databases:

- EMBL:   L42023
- PIR:   I64099
- RefSeq:   NP_439045.1
- ProteinModelPortal:   P44918
- SMR:   P44918
- GeneID:   949839
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0884
- TIGR:   HI_0884
- HOGENOM:   HBG753323
- OMA:   FENHAIN
- ProtClustDB:   PRK11173
- BioCyc:   HINF71421:HI_0884-MONOMER
- GO:   GO:0005737
- GO:   GO:0006350
- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- SMART:   SM00448
- SMART:   SM00862

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C; SSF46894 Bipartite_resp_reg_C-effector; SSF52172 CheY_like

EC number: NA

Molecular weight: Translated: 27425; Mature: 27294

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPKILVVEDEIVTRNTLKGIFEAEGYDVFEAENGVEMHHILANHNINLVVMDINLPGK
CCCCEEEEEECCHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEECCCCEEEEEEEECCCC
NGLLLARELREELSLPLIFLTGRDNEVDKILGLEIGADDYLTKPFNPRELTIRARNLLHR
CCEEEHHHHHHHCCCCEEEEECCCCCCHHEEEEEECCCCCCCCCCCCCEEEHHHHHHHHH
AMPHQEKENTFGREFYRFNGWKLDLNSHSLITPEGQEFKLPRSEFRAMLHFCENPGKLQT
HCCCCCCCCCHHHHHEEECCEEEECCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCH
REELLKKMTGRELKPQDRTVDVTIRRIRKHFEDHPNTPNIIMTIHGEGYRFCGDIE
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEECCCC
>Mature Secondary Structure 
TTPKILVVEDEIVTRNTLKGIFEAEGYDVFEAENGVEMHHILANHNINLVVMDINLPGK
CCCEEEEEECCHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEECCCCEEEEEEEECCCC
NGLLLARELREELSLPLIFLTGRDNEVDKILGLEIGADDYLTKPFNPRELTIRARNLLHR
CCEEEHHHHHHHCCCCEEEEECCCCCCHHEEEEEECCCCCCCCCCCCCEEEHHHHHHHHH
AMPHQEKENTFGREFYRFNGWKLDLNSHSLITPEGQEFKLPRSEFRAMLHFCENPGKLQT
HCCCCCCCCCHHHHHEEECCEEEECCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCH
REELLKKMTGRELKPQDRTVDVTIRRIRKHFEDHPNTPNIIMTIHGEGYRFCGDIE
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800