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The map label for this gene is galT

Identifier: 16272761

GI number: 16272761

Start: 871145

End: 872194

Strand: Reverse

Name: galT

Synonym: HI0820

Alternate gene names: 16272761

Gene position: 872194-871145 (Counterclockwise)

Preceding gene: 16272773

Following gene: 30995403

Centisome position: 47.66

GC content: 39.9

Gene sequence:

>1050_bases
ATGACCGCACTTTTTGAACCTACAGAACATCCACATCGTCGCTACAATCCGTTAATTGATCAATGGGTTTTGGTATCACC
ACATCGTGCCAAACGCCCGTGGCAAGGGCAACAGGAAAAAGTCAATGAAGAACAAAAACCAAGTTATGATCCAACTTGTT
ATCTTTGCCCGAGTAATAAGCGTATTACAGGGGAATTAAATCCAGATTATCGTAAACCTTATGTGTTTAAAAATGATTTT
TCCGCGCTTTTAGAAGATACGCCAGCCCCTGAAAAATCCTCCGATCCTCTTTTCCAAAGTTCTCAAGCTCGTGGGGAAAG
TCGAGTCATTTGTTTCTCTCCCGATCATAGTAAAACATTGCCATTATTGACCGCACTTGAGATTGAAGAAGTGATTAAAG
TATGGCAGGAACAACTTCGTGAGCTTGGTGCGAAATACCAATGGGTGCAAATTTTTGAAAACAAAGGGGCAGCAATGGGG
TGTTCGAACCCACATCCACATGGTCAAATTTGGGCGAATAGTTTCTTGCCAAATGAAGTTGCTCGTGAAGATCGTACACA
ACGTGATTATTTGCTAAAACATGGCTCAGTAATGTTGGTTGATTATGTAAAACGAGAATTGGCGTTGAAAGAACGTATTG
TCGTTGAAACTGAACATTGGATCGCTTTAGTGCCTTATTGGGCTATTTGGCCATTTGAAACATTGCTTTTACCAAAAACT
CATGTAAAACGTTTAACTGAATTAAGTGACGAACAATCAAAAGATCTTGCGGTTATTTTGAAAAAATTGACGACTAAATA
CGACAATCTCTTTGAAACCTCTTTCCCATATTCAATGGGATTTCATGCGGCACCGTTTAATGGAGAAGATAACGAACATT
GGCAGCTACATGCTCATTTTTACCCTCCTCTTTTGCGTTCAGCAACCGTGCGTAAATTTATGGTGGGATATGAAATGTTA
GGCGAAAACCAACGTGATTTAACGGCAGAACAGGCAGCAGAGCGATTACGTGCTTTGAGTGAAGTTCATTATAAAGAAAG
AACTAAATAA

Upstream 100 bases:

>100_bases
TTGCTTATTTTCTTATTTTGTGACAAAGATCACGGTTTATTTACAATAATTTAGTATAAATTAATGTAATCGTTTACATT
GATAAAAAACAGGAGTCAAA

Downstream 100 bases:

>100_bases
TATAGTCAGTCTCCCTCTTTAGCTTTAGCAAAGAGGGGTGCAGATCGAGTATAGATTTAATATAAAGGATAGAAATATGA
CCCCAATCCAAAATGCTCAA

Product: galactose-1-phosphate uridylyltransferase

Products: NA

Alternate protein names: Gal-1-P uridylyltransferase; UDP-glucose--hexose-1-phosphate uridylyltransferase

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MTALFEPTEHPHRRYNPLIDQWVLVSPHRAKRPWQGQQEKVNEEQKPSYDPTCYLCPSNKRITGELNPDYRKPYVFKNDF
SALLEDTPAPEKSSDPLFQSSQARGESRVICFSPDHSKTLPLLTALEIEEVIKVWQEQLRELGAKYQWVQIFENKGAAMG
CSNPHPHGQIWANSFLPNEVAREDRTQRDYLLKHGSVMLVDYVKRELALKERIVVETEHWIALVPYWAIWPFETLLLPKT
HVKRLTELSDEQSKDLAVILKKLTTKYDNLFETSFPYSMGFHAAPFNGEDNEHWQLHAHFYPPLLRSATVRKFMVGYEML
GENQRDLTAEQAAERLRALSEVHYKERTK

Sequences:

>Translated_349_residues
MTALFEPTEHPHRRYNPLIDQWVLVSPHRAKRPWQGQQEKVNEEQKPSYDPTCYLCPSNKRITGELNPDYRKPYVFKNDF
SALLEDTPAPEKSSDPLFQSSQARGESRVICFSPDHSKTLPLLTALEIEEVIKVWQEQLRELGAKYQWVQIFENKGAAMG
CSNPHPHGQIWANSFLPNEVAREDRTQRDYLLKHGSVMLVDYVKRELALKERIVVETEHWIALVPYWAIWPFETLLLPKT
HVKRLTELSDEQSKDLAVILKKLTTKYDNLFETSFPYSMGFHAAPFNGEDNEHWQLHAHFYPPLLRSATVRKFMVGYEML
GENQRDLTAEQAAERLRALSEVHYKERTK
>Mature_348_residues
TALFEPTEHPHRRYNPLIDQWVLVSPHRAKRPWQGQQEKVNEEQKPSYDPTCYLCPSNKRITGELNPDYRKPYVFKNDFS
ALLEDTPAPEKSSDPLFQSSQARGESRVICFSPDHSKTLPLLTALEIEEVIKVWQEQLRELGAKYQWVQIFENKGAAMGC
SNPHPHGQIWANSFLPNEVAREDRTQRDYLLKHGSVMLVDYVKRELALKERIVVETEHWIALVPYWAIWPFETLLLPKTH
VKRLTELSDEQSKDLAVILKKLTTKYDNLFETSFPYSMGFHAAPFNGEDNEHWQLHAHFYPPLLRSATVRKFMVGYEMLG
ENQRDLTAEQAAERLRALSEVHYKERTK

Specific function: Galactose metabolism; second step. [C]

COG id: COG1085

COG function: function code C; Galactose-1-phosphate uridylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family

Homologues:

Organism=Homo sapiens, GI22165416, Length=343, Percent_Identity=59.7667638483965, Blast_Score=429, Evalue=1e-120,
Organism=Escherichia coli, GI1786973, Length=342, Percent_Identity=70.1754385964912, Blast_Score=531, Evalue=1e-152,
Organism=Caenorhabditis elegans, GI17557105, Length=346, Percent_Identity=46.242774566474, Blast_Score=330, Evalue=6e-91,
Organism=Saccharomyces cerevisiae, GI6319492, Length=361, Percent_Identity=51.8005540166205, Blast_Score=379, Evalue=1e-106,
Organism=Drosophila melanogaster, GI24582285, Length=348, Percent_Identity=56.0344827586207, Blast_Score=402, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GAL7_HAEIN (P31764)

Other databases:

- EMBL:   X65934
- EMBL:   L42023
- PIR:   E64096
- RefSeq:   NP_438980.1
- ProteinModelPortal:   P31764
- SMR:   P31764
- GeneID:   950798
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0820
- NMPDR:   fig|71421.1.peg.788
- TIGR:   HI_0820
- HOGENOM:   HBG600409
- OMA:   WATWPYQ
- ProtClustDB:   PRK11720
- BioCyc:   HINF71421:HI_0820-MONOMER
- BRENDA:   2.7.7.12
- InterPro:   IPR001937
- InterPro:   IPR019779
- InterPro:   IPR005850
- InterPro:   IPR005849
- InterPro:   IPR011146
- InterPro:   IPR011151
- Gene3D:   G3DSA:3.30.428.10
- PANTHER:   PTHR11943
- PIRSF:   PIRSF000808
- TIGRFAMs:   TIGR00209

Pfam domain/function: PF02744 GalP_UDP_tr_C; PF01087 GalP_UDP_transf; SSF54197 His_triad-like_motif

EC number: =2.7.7.12

Molecular weight: Translated: 40759; Mature: 40627

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS00117 GAL_P_UDP_TRANSF_I

Important sites: ACT_SITE 167-167

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALFEPTEHPHRRYNPLIDQWVLVSPHRAKRPWQGQQEKVNEEQKPSYDPTCYLCPSNK
CCCCCCCCCCCHHHCCHHHHCEEEECCHHCCCCCCCCHHHCCHHCCCCCCCEEEECCCCC
RITGELNPDYRKPYVFKNDFSALLEDTPAPEKSSDPLFQSSQARGESRVICFSPDHSKTL
EEEECCCCCCCCCEEECCHHHHHHCCCCCCCCCCCCCHHHHHCCCCCEEEEECCCCCCCC
PLLTALEIEEVIKVWQEQLRELGAKYQWVQIFENKGAAMGCSNPHPHGQIWANSFLPNEV
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCEEECCCCCHHH
AREDRTQRDYLLKHGSVMLVDYVKRELALKERIVVETEHWIALVPYWAIWPFETLLLPKT
HHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHEEECCCEEEEECHHHHCCHHHHHCCHH
HVKRLTELSDEQSKDLAVILKKLTTKYDNLFETSFPYSMGFHAAPFNGEDNEHWQLHAHF
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEE
YPPLLRSATVRKFMVGYEMLGENQRDLTAEQAAERLRALSEVHYKERTK
CCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TALFEPTEHPHRRYNPLIDQWVLVSPHRAKRPWQGQQEKVNEEQKPSYDPTCYLCPSNK
CCCCCCCCCCHHHCCHHHHCEEEECCHHCCCCCCCCHHHCCHHCCCCCCCEEEECCCCC
RITGELNPDYRKPYVFKNDFSALLEDTPAPEKSSDPLFQSSQARGESRVICFSPDHSKTL
EEEECCCCCCCCCEEECCHHHHHHCCCCCCCCCCCCCHHHHHCCCCCEEEEECCCCCCCC
PLLTALEIEEVIKVWQEQLRELGAKYQWVQIFENKGAAMGCSNPHPHGQIWANSFLPNEV
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCEEECCCCCHHH
AREDRTQRDYLLKHGSVMLVDYVKRELALKERIVVETEHWIALVPYWAIWPFETLLLPKT
HHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHEEECCCEEEEECHHHHCCHHHHHCCHH
HVKRLTELSDEQSKDLAVILKKLTTKYDNLFETSFPYSMGFHAAPFNGEDNEHWQLHAHF
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEE
YPPLLRSATVRKFMVGYEMLGENQRDLTAEQAAERLRALSEVHYKERTK
CCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1282642; 7542800