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The map label for this gene is nusG

Identifier: 16272657

GI number: 16272657

Start: 765444

End: 766001

Strand: Direct

Name: nusG

Synonym: HI0717

Alternate gene names: 16272657

Gene position: 765444-766001 (Clockwise)

Preceding gene: 16272656

Following gene: 16272658

Centisome position: 41.82

GC content: 37.1

Gene sequence:

>558_bases
ATGACTGAAGAAACAACAGTATCAAAAAAACGTTGGTATGTATTACAAGCGTTTTCTGGCTTTGAAAGTCGTGTAGCTCT
AACTTTACGTGAATACATCAAACAACAACAAATGGAAGATCAATTTGGTGAAGTTTTAGTACCAACTGAAGAAGTAGTGG
AAAATGTAGCAGGTAAACGTCGCAAAAGTGAACGTAAATTTTTTCCAGGTTATGTACTTGTAGAAATGGAAATGAATGAT
GAAACTTGGCATTTAGTAAAAAGTGTGCCAAGAGTGATGGGTTTTATCGGTGGTACACCAGATAAACCTGCACCTATTTC
CAAACGTGAAGCGGATACTATTTTAAATCGTCTTGAACAAAATACTGATAAACCTCGTCATCGTAATGAATATCATCCGG
GAGAGGAAGTTCGTGTGACTGAAGGGCCATTTGCTGATTTTAATGGTACAGTAGAAGAAGTGGATTATGAAAAAGGCCGC
TTAAAAGTGTCTGTATCAATGTTTGGCCGTGCTACACCAGTTGAGCTTGAATTTGGTCAAGTTGAAAAAATACACTAA

Upstream 100 bases:

>100_bases
ATCGTTATCGGGGTAACAATGATTGCTTCTCTCTTCTTTTGGGCAGTAGATTCGATTATTGTGACAGTGATTAATTTCTT
AACTGATTTGAGATTCTAAA

Downstream 100 bases:

>100_bases
GAAATGATTAAAATATAACCGCACTTTTGTAGTGCGGTTTTTTGTTTTTAATGTTTGTTGAAACAGCATAAAAGAGTGTT
TTTATACACAAAATTTGTTG

Product: transcription antitermination protein NusG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MTEETTVSKKRWYVLQAFSGFESRVALTLREYIKQQQMEDQFGEVLVPTEEVVENVAGKRRKSERKFFPGYVLVEMEMND
ETWHLVKSVPRVMGFIGGTPDKPAPISKREADTILNRLEQNTDKPRHRNEYHPGEEVRVTEGPFADFNGTVEEVDYEKGR
LKVSVSMFGRATPVELEFGQVEKIH

Sequences:

>Translated_185_residues
MTEETTVSKKRWYVLQAFSGFESRVALTLREYIKQQQMEDQFGEVLVPTEEVVENVAGKRRKSERKFFPGYVLVEMEMND
ETWHLVKSVPRVMGFIGGTPDKPAPISKREADTILNRLEQNTDKPRHRNEYHPGEEVRVTEGPFADFNGTVEEVDYEKGR
LKVSVSMFGRATPVELEFGQVEKIH
>Mature_184_residues
TEETTVSKKRWYVLQAFSGFESRVALTLREYIKQQQMEDQFGEVLVPTEEVVENVAGKRRKSERKFFPGYVLVEMEMNDE
TWHLVKSVPRVMGFIGGTPDKPAPISKREADTILNRLEQNTDKPRHRNEYHPGEEVRVTEGPFADFNGTVEEVDYEKGRL
KVSVSMFGRATPVELEFGQVEKIH

Specific function: Influences transcription termination and antitermination. Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase

COG id: COG0250

COG function: function code K; Transcription antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KOW domain

Homologues:

Organism=Escherichia coli, GI1790414, Length=175, Percent_Identity=75.4285714285714, Blast_Score=275, Evalue=1e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUSG_HAEIN (P43916)

Other databases:

- EMBL:   L42023
- PIR:   G64088
- RefSeq:   NP_438875.1
- ProteinModelPortal:   P43916
- SMR:   P43916
- GeneID:   950637
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0717
- NMPDR:   fig|71421.1.peg.685
- TIGR:   HI_0717
- HOGENOM:   HBG751162
- OMA:   VASGCEK
- ProtClustDB:   PRK05609
- BioCyc:   HINF71421:HI_0717-MONOMER
- InterPro:   IPR005824
- InterPro:   IPR001062
- InterPro:   IPR015869
- InterPro:   IPR006645
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.30.30.30
- Gene3D:   G3DSA:3.30.70.940
- PRINTS:   PR00338
- SMART:   SM00739
- SMART:   SM00738
- TIGRFAMs:   TIGR00922

Pfam domain/function: PF00467 KOW; PF02357 NusG; SSF82679 Transcrpt_antiterm_NusG_N; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 21381; Mature: 21250

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS01014 NUSG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEETTVSKKRWYVLQAFSGFESRVALTLREYIKQQQMEDQFGEVLVPTEEVVENVAGKR
CCCCCCCCCHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCEECCHHHHHHHHHHHH
RKSERKFFPGYVLVEMEMNDETWHLVKSVPRVMGFIGGTPDKPAPISKREADTILNRLEQ
HHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
NTDKPRHRNEYHPGEEVRVTEGPFADFNGTVEEVDYEKGRLKVSVSMFGRATPVELEFGQ
CCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHCCCCCCEEEEEEECCCCCCCEEEECCC
VEKIH
CCCCC
>Mature Secondary Structure 
TEETTVSKKRWYVLQAFSGFESRVALTLREYIKQQQMEDQFGEVLVPTEEVVENVAGKR
CCCCCCCCHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCEECCHHHHHHHHHHHH
RKSERKFFPGYVLVEMEMNDETWHLVKSVPRVMGFIGGTPDKPAPISKREADTILNRLEQ
HHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
NTDKPRHRNEYHPGEEVRVTEGPFADFNGTVEEVDYEKGRLKVSVSMFGRATPVELEFGQ
CCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHCCCCCCEEEEEEECCCCCCCEEEECCC
VEKIH
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800