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The map label for this gene is slyD

Identifier: 16272640

GI number: 16272640

Start: 746006

End: 746578

Strand: Reverse

Name: slyD

Synonym: HI0699

Alternate gene names: 16272640

Gene position: 746578-746006 (Counterclockwise)

Preceding gene: 16272641

Following gene: 16272639

Centisome position: 40.79

GC content: 44.5

Gene sequence:

>573_bases
ATGAAAGTAGAAAAAAATGTAGTGGTGAGCATTTCTTACCAAGTTCGCACACAAGATGGCGTATTGGTAGATGAAGCTCC
AGCAAATCAACCACTCGAATATTTACAAGGTCACAATAATTTAGTGATTGGTCTTGAAAAAGCACTTGAAGGTAAAGAAG
TTGGCGACAAATTTGAAGTACGTGTACAACCTGAAGAAGGTTACGGCGCATACAGCGAAAATATGGTTCAACGTGTACCA
AAAGATGTATTCCAAGGTGTTGATGAACTTGAAGTCGGTATGCGTTTCTTAGCGGATACTGACATTGGCCCAGTTCCAGT
GGTGATTACTGAAATCGATGGCGATGAAGTTGTAGTTGATGGAAACCATATGTTAGCGGGGCAAGAATTACACTTCACCG
TTGAGGTTGTTGCAGCGCGTGAAGCAACGTTAGAAGAAATTGCTCACGGCCACGTTCACGGTGCGCACAGCCACGATGAT
GACGAAGAAGGTCACGGTTGTGGCTGTGGTGGTCATCATCACGAACATAATCACGAACATAATCACGGCAGCTGTGGTTG
CGGCGGTCACTAA

Upstream 100 bases:

>100_bases
GAAGAGCCTCGTGTTCATTAATCCGTAAAGTCTTGCGCGCGGAATAATTTTCGCTACAATGGTACGACTTTTTTAACGGA
TTTTTTATAAGGAAAACATA

Downstream 100 bases:

>100_bases
TTAAAACAGCTCAAAAATTTACCGCACTTTGGCAATGAAGTGCGGTATTTTTTATGAAAAAACCGACAAAATGCACTGAA
AATATTGGATCCTAACGAAC

Product: peptidyl-prolyl cis-trans isomerase FKBP-type

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MKVEKNVVVSISYQVRTQDGVLVDEAPANQPLEYLQGHNNLVIGLEKALEGKEVGDKFEVRVQPEEGYGAYSENMVQRVP
KDVFQGVDELEVGMRFLADTDIGPVPVVITEIDGDEVVVDGNHMLAGQELHFTVEVVAAREATLEEIAHGHVHGAHSHDD
DEEGHGCGCGGHHHEHNHEHNHGSCGCGGH

Sequences:

>Translated_190_residues
MKVEKNVVVSISYQVRTQDGVLVDEAPANQPLEYLQGHNNLVIGLEKALEGKEVGDKFEVRVQPEEGYGAYSENMVQRVP
KDVFQGVDELEVGMRFLADTDIGPVPVVITEIDGDEVVVDGNHMLAGQELHFTVEVVAAREATLEEIAHGHVHGAHSHDD
DEEGHGCGCGGHHHEHNHEHNHGSCGCGGH
>Mature_190_residues
MKVEKNVVVSISYQVRTQDGVLVDEAPANQPLEYLQGHNNLVIGLEKALEGKEVGDKFEVRVQPEEGYGAYSENMVQRVP
KDVFQGVDELEVGMRFLADTDIGPVPVVITEIDGDEVVVDGNHMLAGQELHFTVEVVAAREATLEEIAHGHVHGAHSHDD
DEEGHGCGCGGHHHEHNHEHNHGSCGCGGH

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain

Homologues:

Organism=Escherichia coli, GI1789748, Length=148, Percent_Identity=70.2702702702703, Blast_Score=207, Evalue=3e-55,
Organism=Escherichia coli, GI1786211, Length=139, Percent_Identity=35.2517985611511, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SLYD_HAEIN (P44830)

Other databases:

- EMBL:   L42023
- PIR:   D64087
- RefSeq:   NP_438858.1
- ProteinModelPortal:   P44830
- SMR:   P44830
- GeneID:   949724
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0699
- NMPDR:   fig|71421.1.peg.668
- TIGR:   HI_0699
- HOGENOM:   HBG731200
- OMA:   HGHIHAH
- ProtClustDB:   CLSK808441
- BioCyc:   HINF71421:HI_0699-MONOMER
- BRENDA:   5.2.1.8
- GO:   GO:0005737
- InterPro:   IPR001179
- PANTHER:   PTHR10516

Pfam domain/function: PF00254 FKBP_C

EC number: =5.2.1.8

Molecular weight: Translated: 20658; Mature: 20658

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVEKNVVVSISYQVRTQDGVLVDEAPANQPLEYLQGHNNLVIGLEKALEGKEVGDKFEV
CCCCCEEEEEEEEEEECCCCEEEECCCCCCCHHHHCCCCCEEEEEHHHCCCCCCCCEEEE
RVQPEEGYGAYSENMVQRVPKDVFQGVDELEVGMRFLADTDIGPVPVVITEIDGDEVVVD
EEECCCCCCCHHHHHHHHCCHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEC
GNHMLAGQELHFTVEVVAAREATLEEIAHGHVHGAHSHDDDEEGHGCGCGGHHHEHNHEH
CCEEEECCEEEEEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NHGSCGCGGH
CCCCCCCCCC
>Mature Secondary Structure
MKVEKNVVVSISYQVRTQDGVLVDEAPANQPLEYLQGHNNLVIGLEKALEGKEVGDKFEV
CCCCCEEEEEEEEEEECCCCEEEECCCCCCCHHHHCCCCCEEEEEHHHCCCCCCCCEEEE
RVQPEEGYGAYSENMVQRVPKDVFQGVDELEVGMRFLADTDIGPVPVVITEIDGDEVVVD
EEECCCCCCCHHHHHHHHCCHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEC
GNHMLAGQELHFTVEVVAAREATLEEIAHGHVHGAHSHDDDEEGHGCGCGGHHHEHNHEH
CCEEEECCEEEEEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NHGSCGCGGH
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800