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The map label for this gene is yheS [C]

Identifier: 16272601

GI number: 16272601

Start: 700653

End: 702569

Strand: Reverse

Name: yheS [C]

Synonym: HI0658

Alternate gene names: 16272601

Gene position: 702569-700653 (Counterclockwise)

Preceding gene: 16272602

Following gene: 16272600

Centisome position: 38.39

GC content: 40.64

Gene sequence:

>1917_bases
ATGATTATATTTAGTAACTTATCCTTAAAACGAGGGCAAACGGAACTTCTCGAAAATGCGTCTGCTACGATTAATCCCAA
GCAAAAAGTCGGTTTGGTGGGGAAAAATGGTTGTGGAAAATCTTCGCTTTTTGCCTTATTAAAAAAAGAATTAATGCCAG
AGGGCGGTGAGGTGAATTATCCAGCAAATTGGCGGGTATCTTGGGTAAATCAAGAAACGCCTGCATTGGATATTTCTGCG
ATTGATTATGTGATTCAAGGGGATCGTGAATATTGCCGTTTGCAACAAAAGCTTGAACGTGCAAATGAACGCAATGACGG
TAACGCCATTGCACGCATTCACGGGCAATTAGAAACCTTGGATGCGTGGACAATTCAATCGCGTGCCGCGTCTTTATTGC
ATGGTTTAGGATTTAGCCAAGAAGAAACAATACAGCCAGTGAAAGCCTTTTCGGGCGGTTGGCGGATGCGTTTGAATTTG
GCACAGGCATTGCTTTGTCCGTCAGATTTATTATTACTGGATGAACCGACGAACCATTTGGATTTGGATGCGGTTATTTG
GTTGGAACGATGGTTAGTGCAATATCAAGGCACTTTAGTATTAATTTCTCACGATCGTGATTTTCTTGATCCAATTGTGA
CAAAAATCCTCCATATCGAAAATCAGAAGCTCAACGAATACACGGGCGATTATTCTTCCTTTGAAGTGCAACGAGCCACT
AAACTGGCTCAACAAACAGCGATGTATCGTCAGCAACAACAAAAGATTTCCCATTTACAAAAATATATTGATCGCTTTAA
AGCCAAAGCCACTAAAGCCAAACAGGCACAAAGCCGTATGAAAGCACTAGAAAGAATGGAGCTGATTGCACCTGCTTATG
TGGATAATCCTTTTACTTTTGAATTTCGTCCACCGCAATCCTTGCCGAATCCCTTAGTGATGATTGAGCAAGCGAGTGCA
GGTTATGGCATCGGCGAAAGTGCGGTAGAAATTTTAAGTAAAATTAAACTGAATTTAGTGCCAGGTTCGCGCATTGGTTT
ACTCGGGAAAAATGGTGCAGGAAAATCAACACTGATTAAACTTTTAGCGGGAGAACTGACCGCACTTTCAGGCACGGTAC
AATTAGCTAAAGGTGTTCAACTTGGTTATTTTGCTCAGCATCAATTAGATACTTTACGCGCAGACGAATCTGCTCTGTGG
CATATGCAAAAACTCGCGCCTGAGCAAACGGAGCAACAAGTTCGGGATTATTTAGGCAGTTTTGCGTTTCACGGCGATAA
AGTAAATCAAGCAGTGAAATCTTTTTCTGGAGGAGAAAAAGCTCGTTTGGTGTTGGCTTTGATTGTTTGGCAACGCCCGA
ATTTGTTACTACTTGATGAACCGACTAACCATTTGGATTTGGATATGCGTCAAGCATTAACGGAAGCATTGGTGGATTAC
GAAGGTTCTTTGGTGGTGGTGTCGCACGATCGTCATTTATTACGCAATACCGTGGAAGAATTTTATTTAGTTCACGATAA
AAAAGTGGAAGAATTTAAAGGCGATTTAGAAGACTATCAAAAATGGCTGAGTGAACAAAACAGTACGTCTGAAAATAAAG
TTTCGGAAAAAGTGGGCGATAATGAAAATTCGGTTCAAAATCGCAAGGAACAAAAACGCCGTGAAGCAGAGTTACGCCAA
CAAACTGCACCATTACGTAAAAAAATCACGCAATTAGAAGAAAAAATGAATAAATTTTCTTCTGAGCTTGCGAACATAGA
AAATCAACTGGCAGATACCGAATTATATAATGCCGAAAATAAAGAAAAATTGACCGCACTTTTGGCTCAACAAGTGGATG
TGAAGAAAGCATTAGATGATGTAGAAACGGAATGGATGACTGCACAGGAAGAATTGGAAGAAATGCTTCAAGCATAA

Upstream 100 bases:

>100_bases
GTGGCTTTTTTGACTAGAAAATCGATAAAATCGGAATAGACTGTTCCGAGAAAAGAAAAAATATTGCAAAATAGCCTCAA
ATTAAGACCTATGTAGAAAA

Downstream 100 bases:

>100_bases
GGATAGATTATGAATCAAAGCCTTTTTCATCATAGCAAACAACAGGAATATTGCCCTCAATGTGGTGCGCCGTTGCAAAT
TAAACAAGGCAAAAAAGGGC

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 638; Mature: 638

Protein sequence:

>638_residues
MIIFSNLSLKRGQTELLENASATINPKQKVGLVGKNGCGKSSLFALLKKELMPEGGEVNYPANWRVSWVNQETPALDISA
IDYVIQGDREYCRLQQKLERANERNDGNAIARIHGQLETLDAWTIQSRAASLLHGLGFSQEETIQPVKAFSGGWRMRLNL
AQALLCPSDLLLLDEPTNHLDLDAVIWLERWLVQYQGTLVLISHDRDFLDPIVTKILHIENQKLNEYTGDYSSFEVQRAT
KLAQQTAMYRQQQQKISHLQKYIDRFKAKATKAKQAQSRMKALERMELIAPAYVDNPFTFEFRPPQSLPNPLVMIEQASA
GYGIGESAVEILSKIKLNLVPGSRIGLLGKNGAGKSTLIKLLAGELTALSGTVQLAKGVQLGYFAQHQLDTLRADESALW
HMQKLAPEQTEQQVRDYLGSFAFHGDKVNQAVKSFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALVDY
EGSLVVVSHDRHLLRNTVEEFYLVHDKKVEEFKGDLEDYQKWLSEQNSTSENKVSEKVGDNENSVQNRKEQKRREAELRQ
QTAPLRKKITQLEEKMNKFSSELANIENQLADTELYNAENKEKLTALLAQQVDVKKALDDVETEWMTAQEELEEMLQA

Sequences:

>Translated_638_residues
MIIFSNLSLKRGQTELLENASATINPKQKVGLVGKNGCGKSSLFALLKKELMPEGGEVNYPANWRVSWVNQETPALDISA
IDYVIQGDREYCRLQQKLERANERNDGNAIARIHGQLETLDAWTIQSRAASLLHGLGFSQEETIQPVKAFSGGWRMRLNL
AQALLCPSDLLLLDEPTNHLDLDAVIWLERWLVQYQGTLVLISHDRDFLDPIVTKILHIENQKLNEYTGDYSSFEVQRAT
KLAQQTAMYRQQQQKISHLQKYIDRFKAKATKAKQAQSRMKALERMELIAPAYVDNPFTFEFRPPQSLPNPLVMIEQASA
GYGIGESAVEILSKIKLNLVPGSRIGLLGKNGAGKSTLIKLLAGELTALSGTVQLAKGVQLGYFAQHQLDTLRADESALW
HMQKLAPEQTEQQVRDYLGSFAFHGDKVNQAVKSFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALVDY
EGSLVVVSHDRHLLRNTVEEFYLVHDKKVEEFKGDLEDYQKWLSEQNSTSENKVSEKVGDNENSVQNRKEQKRREAELRQ
QTAPLRKKITQLEEKMNKFSSELANIENQLADTELYNAENKEKLTALLAQQVDVKKALDDVETEWMTAQEELEEMLQA
>Mature_638_residues
MIIFSNLSLKRGQTELLENASATINPKQKVGLVGKNGCGKSSLFALLKKELMPEGGEVNYPANWRVSWVNQETPALDISA
IDYVIQGDREYCRLQQKLERANERNDGNAIARIHGQLETLDAWTIQSRAASLLHGLGFSQEETIQPVKAFSGGWRMRLNL
AQALLCPSDLLLLDEPTNHLDLDAVIWLERWLVQYQGTLVLISHDRDFLDPIVTKILHIENQKLNEYTGDYSSFEVQRAT
KLAQQTAMYRQQQQKISHLQKYIDRFKAKATKAKQAQSRMKALERMELIAPAYVDNPFTFEFRPPQSLPNPLVMIEQASA
GYGIGESAVEILSKIKLNLVPGSRIGLLGKNGAGKSTLIKLLAGELTALSGTVQLAKGVQLGYFAQHQLDTLRADESALW
HMQKLAPEQTEQQVRDYLGSFAFHGDKVNQAVKSFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALVDY
EGSLVVVSHDRHLLRNTVEEFYLVHDKKVEEFKGDLEDYQKWLSEQNSTSENKVSEKVGDNENSVQNRKEQKRREAELRQ
QTAPLRKKITQLEEKMNKFSSELANIENQLADTELYNAENKEKLTALLAQQVDVKKALDDVETEWMTAQEELEEMLQA

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains

Homologues:

Organism=Homo sapiens, GI27881506, Length=539, Percent_Identity=35.621521335807, Blast_Score=329, Evalue=4e-90,
Organism=Homo sapiens, GI10947137, Length=539, Percent_Identity=35.621521335807, Blast_Score=329, Evalue=6e-90,
Organism=Homo sapiens, GI148612853, Length=530, Percent_Identity=34.3396226415094, Blast_Score=328, Evalue=1e-89,
Organism=Homo sapiens, GI10947135, Length=553, Percent_Identity=32.5497287522604, Blast_Score=249, Evalue=5e-66,
Organism=Homo sapiens, GI69354671, Length=553, Percent_Identity=32.5497287522604, Blast_Score=249, Evalue=7e-66,
Organism=Escherichia coli, GI1789751, Length=636, Percent_Identity=68.5534591194968, Blast_Score=914, Evalue=0.0,
Organism=Escherichia coli, GI1787041, Length=528, Percent_Identity=32.9545454545455, Blast_Score=311, Evalue=1e-85,
Organism=Escherichia coli, GI1787182, Length=625, Percent_Identity=27.84, Blast_Score=241, Evalue=1e-64,
Organism=Escherichia coli, GI2367384, Length=531, Percent_Identity=30.1318267419962, Blast_Score=211, Evalue=8e-56,
Organism=Escherichia coli, GI1788165, Length=196, Percent_Identity=32.6530612244898, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI48994997, Length=227, Percent_Identity=24.2290748898678, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1787758, Length=200, Percent_Identity=24.5, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1788002, Length=186, Percent_Identity=32.258064516129, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=537, Percent_Identity=37.0577281191806, Blast_Score=343, Evalue=1e-94,
Organism=Caenorhabditis elegans, GI17555318, Length=531, Percent_Identity=33.5216572504708, Blast_Score=312, Evalue=3e-85,
Organism=Caenorhabditis elegans, GI17559834, Length=534, Percent_Identity=32.3970037453184, Blast_Score=278, Evalue=5e-75,
Organism=Caenorhabditis elegans, GI17541710, Length=198, Percent_Identity=29.7979797979798, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17556528, Length=236, Percent_Identity=25.4237288135593, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321121, Length=545, Percent_Identity=34.6788990825688, Blast_Score=333, Evalue=7e-92,
Organism=Saccharomyces cerevisiae, GI6320874, Length=532, Percent_Identity=34.3984962406015, Blast_Score=317, Evalue=5e-87,
Organism=Saccharomyces cerevisiae, GI6325030, Length=389, Percent_Identity=29.5629820051414, Blast_Score=154, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6324314, Length=388, Percent_Identity=29.3814432989691, Blast_Score=131, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6323278, Length=389, Percent_Identity=28.5347043701799, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24666836, Length=531, Percent_Identity=36.1581920903955, Blast_Score=369, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24642252, Length=546, Percent_Identity=36.8131868131868, Blast_Score=350, Evalue=1e-96,
Organism=Drosophila melanogaster, GI18859989, Length=546, Percent_Identity=36.8131868131868, Blast_Score=350, Evalue=1e-96,
Organism=Drosophila melanogaster, GI24641342, Length=543, Percent_Identity=32.5966850828729, Blast_Score=295, Evalue=8e-80,
Organism=Drosophila melanogaster, GI116007184, Length=149, Percent_Identity=35.5704697986577, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221500365, Length=149, Percent_Identity=35.5704697986577, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45550390, Length=233, Percent_Identity=28.755364806867, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y658_HAEIN (P44808)

Other databases:

- EMBL:   L42023
- PIR:   C64156
- RefSeq:   NP_438818.1
- ProteinModelPortal:   P44808
- GeneID:   949699
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0658
- NMPDR:   fig|71421.1.peg.628
- TIGR:   HI_0658
- HOGENOM:   HBG758042
- OMA:   GWIKAYQ
- ProtClustDB:   CLSK870537
- BioCyc:   HINF71421:HI_0658-MONOMER
- GO:   GO:0006810
- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- SMART:   SM00382

Pfam domain/function: PF00005 ABC_tran

EC number: NA

Molecular weight: Translated: 72232; Mature: 72232

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00211 ABC_TRANSPORTER_1; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIFSNLSLKRGQTELLENASATINPKQKVGLVGKNGCGKSSLFALLKKELMPEGGEVNY
CEEECCCCCCCCHHHHHHCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
PANWRVSWVNQETPALDISAIDYVIQGDREYCRLQQKLERANERNDGNAIARIHGQLETL
CCCCEEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHH
DAWTIQSRAASLLHGLGFSQEETIQPVKAFSGGWRMRLNLAQALLCPSDLLLLDEPTNHL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHCCCCEEEEECCCCCC
DLDAVIWLERWLVQYQGTLVLISHDRDFLDPIVTKILHIENQKLNEYTGDYSSFEVQRAT
CHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHH
KLAQQTAMYRQQQQKISHLQKYIDRFKAKATKAKQAQSRMKALERMELIAPAYVDNPFTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
EFRPPQSLPNPLVMIEQASAGYGIGESAVEILSKIKLNLVPGSRIGLLGKNGAGKSTLIK
EECCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHEEECCCCCEEEEECCCCCHHHHHH
LLAGELTALSGTVQLAKGVQLGYFAQHQLDTLRADESALWHMQKLAPEQTEQQVRDYLGS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHH
FAFHGDKVNQAVKSFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALVDY
HHHCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHCC
EGSLVVVSHDRHLLRNTVEEFYLVHDKKVEEFKGDLEDYQKWLSEQNSTSENKVSEKVGD
CCCEEEEECCHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHCCC
NENSVQNRKEQKRREAELRQQTAPLRKKITQLEEKMNKFSSELANIENQLADTELYNAEN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KEKLTALLAQQVDVKKALDDVETEWMTAQEELEEMLQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIIFSNLSLKRGQTELLENASATINPKQKVGLVGKNGCGKSSLFALLKKELMPEGGEVNY
CEEECCCCCCCCHHHHHHCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
PANWRVSWVNQETPALDISAIDYVIQGDREYCRLQQKLERANERNDGNAIARIHGQLETL
CCCCEEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHH
DAWTIQSRAASLLHGLGFSQEETIQPVKAFSGGWRMRLNLAQALLCPSDLLLLDEPTNHL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHCCCCEEEEECCCCCC
DLDAVIWLERWLVQYQGTLVLISHDRDFLDPIVTKILHIENQKLNEYTGDYSSFEVQRAT
CHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHH
KLAQQTAMYRQQQQKISHLQKYIDRFKAKATKAKQAQSRMKALERMELIAPAYVDNPFTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
EFRPPQSLPNPLVMIEQASAGYGIGESAVEILSKIKLNLVPGSRIGLLGKNGAGKSTLIK
EECCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHEEECCCCCEEEEECCCCCHHHHHH
LLAGELTALSGTVQLAKGVQLGYFAQHQLDTLRADESALWHMQKLAPEQTEQQVRDYLGS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHH
FAFHGDKVNQAVKSFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALVDY
HHHCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHCC
EGSLVVVSHDRHLLRNTVEEFYLVHDKKVEEFKGDLEDYQKWLSEQNSTSENKVSEKVGD
CCCEEEEECCHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHCCC
NENSVQNRKEQKRREAELRQQTAPLRKKITQLEEKMNKFSSELANIENQLADTELYNAEN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KEKLTALLAQQVDVKKALDDVETEWMTAQEELEEMLQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023