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The map label for this gene is glpR

Identifier: 16272561

GI number: 16272561

Start: 652390

End: 653157

Strand: Direct

Name: glpR

Synonym: HI0619

Alternate gene names: 16272561

Gene position: 652390-653157 (Clockwise)

Preceding gene: 16272560

Following gene: 16272564

Centisome position: 35.65

GC content: 39.71

Gene sequence:

>768_bases
ATGAAACAATCGTTACGCCATCAAAAAATTATTAAACTGGTGGAACAATCTGGCTATTTAAGCACGGAAGAATTGGTTGC
TGCCTTAGATGTTAGCCCTCAAACGATTCGTCGTGATTTGAATATTTTGGCGGAGTTAGATTTAATTCGCCGCCATCACG
GTGGTGCGGCATCGCCATCTTCTGCAGAAAATTCTGATTACGTGGATCGTAAACAATTCTTTTCATTACAAAAAAATAAT
ATTGCACAAGAAGTTGCGAAGTTGATTCCTAACGGTGCATCGTTGTTTATTGATATTGGTACGACGCCGGAGGCTGTCGC
CAATGCGTTGCTTGGTCATGAAAAACTCAGAATTGTGACGAACAATCTGAATGCCGCTCATCTTTTACGCCAAAATGAAA
GTTTTGATATTGTCATGGCGGGCGGATCATTACGAATGGATGGTGGAATTATCGGCGAAGCTACGGTAAATTTTATTTCT
CAATTTCGCCTAGATTTCGGTATTTTAGGGATTAGTGCGATTGATGCAGATGGTTCATTATTGGATTATGATTACCATGA
AGTACAAGTAAAACGAGCGATTATTGAAAGTTCACGTCAGACCTTATTAGTGGCCGATCACTCTAAATTTACTCGCCAAG
CGATTGTTCGCTTGGGCGAATTAAGTGATGTGGAATATTTGTTTACAGGTGATGTTCCTGAGGGCATTGTCAATTATTTG
AAAGAGCAGAAAACGAAATTGGTTTTATGTAATGGTAAAGTGCGGTAA

Upstream 100 bases:

>100_bases
TTTCAGGCTTGATTGTCGGCTTGATTTGGGGATTTATTGATAGCAAATTGCGCAAAAATTCGCTAGAGTAAGTCCGTTTA
ATTTGGATAAAGGATTCGCT

Downstream 100 bases:

>100_bases
AAATATCTTTGATTTTCTTATTAATTTGTCGATAAAAGAAGCTATTACTCTTAATTTTTGATTTAATTGAAATTTATCTA
AAAGTAATCTAAATATTCTC

Product: glycerol-3-phosphate regulon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MKQSLRHQKIIKLVEQSGYLSTEELVAALDVSPQTIRRDLNILAELDLIRRHHGGAASPSSAENSDYVDRKQFFSLQKNN
IAQEVAKLIPNGASLFIDIGTTPEAVANALLGHEKLRIVTNNLNAAHLLRQNESFDIVMAGGSLRMDGGIIGEATVNFIS
QFRLDFGILGISAIDADGSLLDYDYHEVQVKRAIIESSRQTLLVADHSKFTRQAIVRLGELSDVEYLFTGDVPEGIVNYL
KEQKTKLVLCNGKVR

Sequences:

>Translated_255_residues
MKQSLRHQKIIKLVEQSGYLSTEELVAALDVSPQTIRRDLNILAELDLIRRHHGGAASPSSAENSDYVDRKQFFSLQKNN
IAQEVAKLIPNGASLFIDIGTTPEAVANALLGHEKLRIVTNNLNAAHLLRQNESFDIVMAGGSLRMDGGIIGEATVNFIS
QFRLDFGILGISAIDADGSLLDYDYHEVQVKRAIIESSRQTLLVADHSKFTRQAIVRLGELSDVEYLFTGDVPEGIVNYL
KEQKTKLVLCNGKVR
>Mature_255_residues
MKQSLRHQKIIKLVEQSGYLSTEELVAALDVSPQTIRRDLNILAELDLIRRHHGGAASPSSAENSDYVDRKQFFSLQKNN
IAQEVAKLIPNGASLFIDIGTTPEAVANALLGHEKLRIVTNNLNAAHLLRQNESFDIVMAGGSLRMDGGIIGEATVNFIS
QFRLDFGILGISAIDADGSLLDYDYHEVQVKRAIIESSRQTLLVADHSKFTRQAIVRLGELSDVEYLFTGDVPEGIVNYL
KEQKTKLVLCNGKVR

Specific function: Repressor of the glycerol-3-phosphate regulon

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1789829, Length=252, Percent_Identity=61.9047619047619, Blast_Score=306, Evalue=9e-85,
Organism=Escherichia coli, GI87082344, Length=246, Percent_Identity=40.650406504065, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI226510968, Length=247, Percent_Identity=30.7692307692308, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788069, Length=248, Percent_Identity=27.4193548387097, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789519, Length=238, Percent_Identity=27.7310924369748, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1789170, Length=234, Percent_Identity=29.0598290598291, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789059, Length=234, Percent_Identity=28.6324786324786, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1787540, Length=209, Percent_Identity=29.6650717703349, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790753, Length=249, Percent_Identity=24.4979919678715, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787063, Length=256, Percent_Identity=25.78125, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): GLPR_HAEIN (P44784)

Other databases:

- EMBL:   L42023
- PIR:   A64082
- RefSeq:   NP_438777.1
- ProteinModelPortal:   P44784
- SMR:   P44784
- GeneID:   950682
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0619
- TIGR:   HI_0619
- HOGENOM:   HBG694151
- OMA:   AYILMQN
- ProtClustDB:   CLSK870483
- BioCyc:   HINF71421:HI_0619-MONOMER
- GO:   GO:0005622
- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00037
- SMART:   SM00420

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR

EC number: NA

Molecular weight: Translated: 28184; Mature: 28184

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00894 HTH_DEOR_1; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQSLRHQKIIKLVEQSGYLSTEELVAALDVSPQTIRRDLNILAELDLIRRHHGGAASPS
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SAENSDYVDRKQFFSLQKNNIAQEVAKLIPNGASLFIDIGTTPEAVANALLGHEKLRIVT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCEEEEEE
NNLNAAHLLRQNESFDIVMAGGSLRMDGGIIGEATVNFISQFRLDFGILGISAIDADGSL
CCCCHHHHHHCCCCEEEEEECCCEEECCCEEHHHHHHHHHHHHHHHHEEEEEEECCCCCE
LDYDYHEVQVKRAIIESSRQTLLVADHSKFTRQAIVRLGELSDVEYLFTGDVPEGIVNYL
ECCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHH
KEQKTKLVLCNGKVR
HHCCCEEEEECCCCC
>Mature Secondary Structure
MKQSLRHQKIIKLVEQSGYLSTEELVAALDVSPQTIRRDLNILAELDLIRRHHGGAASPS
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SAENSDYVDRKQFFSLQKNNIAQEVAKLIPNGASLFIDIGTTPEAVANALLGHEKLRIVT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCEEEEEE
NNLNAAHLLRQNESFDIVMAGGSLRMDGGIIGEATVNFISQFRLDFGILGISAIDADGSL
CCCCHHHHHHCCCCEEEEEECCCEEECCCEEHHHHHHHHHHHHHHHHEEEEEEECCCCCE
LDYDYHEVQVKRAIIESSRQTLLVADHSKFTRQAIVRLGELSDVEYLFTGDVPEGIVNYL
ECCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHH
KEQKTKLVLCNGKVR
HHCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800