Click here to switch to the map view.

The map label for this gene is fucP

Identifier: 16272552

GI number: 16272552

Start: 641451

End: 642737

Strand: Reverse

Name: fucP

Synonym: HI0610

Alternate gene names: 16272552

Gene position: 642737-641451 (Counterclockwise)

Preceding gene: 16272553

Following gene: 16272551

Centisome position: 35.12

GC content: 39.16

Gene sequence:

>1287_bases
ATGAACGCCAAAGTTTTAGAAAAGAAATTCATCGTCCCCTTTGTGCTTATTACTAGCTTATTTGCTCTTTGGGGATTTGC
CAACGACATTACCAATCCGATGGTTGCGGTATTTCAAACAGTAATGGAAATTCCAGCCTCAGAAGCGGCATTGGTACAAT
TAGCTTTTTATGGAGGATACGGCACAATGGCTATTCCTGCGGCATTATTTGCCAGTCGCTATAGCTACAAAGCGGGGATT
CTTCTGGGGCTTGCTCTTTATGCAATAGGTGCATTTTTATTTTGGCCAGCTGCGCAATATGAAATATTTAATTTCTTTTT
AGTCTCCCTTTATATTTTAACCTTTGGGCTCGCTTTTTTGGAAACCACTGCCAATCCTTATATTCTCGCAATGGGAGATC
CTCAAACAGCTACTCGACGTTTAAATTTCGCACAATCATTTAATCCACTTGGTTCAATTACAGGTATGTTTGTTGCTTCC
CAGTTAGTCCTAACTAATCTTGAATCTGACAAACGTGATGCTGCAGGTAATTTGATTTTCCACACCCTGTCTGAAGCAGA
AAAAATGAGTATTCGCACCCATGATTTAGCTGAAATTCGCGATCCTTACATAGCACTCGGTTTTGTCGTGGTTGCAGTGT
TTATTATCATTGGATTGAAAAAAATGCCAGCCGTAAAAATAGAAGAGGCCGGACAAATCAGCTTTAAAACAGCAGTAAGC
CGACTGGCTCAAAAAGCCAAATATCGTGAAGGCGTGATCGCACAAGCCTTTTACGTAGGTGTTCAAATCATGTGTTGGAC
ATTTATCGTACAATACGCTGAACGTTTAGGTTTTACTAAAGCTGAAGGGCAAAACTTTAACATCATTGCTATGGCTATTT
TTATTAGCAGTCGCTTTATTAGCACGGCATTAATGAAATATTTAAAAGCAGAATTTATGCTGATGCTCTTTGCTATTGGT
GGTTTTTTAAGTATTCTCGGAGTTATCTTTATTGACGGTGTATGGGGTCTATACTGCCTAATTTTAACCTCAGGTTTTAT
GCCTTTAATGTTCCCTACCATTTATGGTATTGCCCTCTATGGCTTAAAAGAGGAATCGACATTAGGAGCTGCAGGTTTAG
TAATGGCTATTGTAGGCGGCGCATTAATGCCACCACTACAAGGAATGATTATTGACCAAGGCGAAGTTATGGGACTTCCA
GCAGTAAATTTTTCCTTTATCCTACCATTAATCTGTTTTGTAGTAATTGCCATTTATGGCTTCAGAGCTTGGAAAATACT
TAAATAG

Upstream 100 bases:

>100_bases
AGCAAATGCAGGTAGTGTTAGGTAAATTCCACACCTATGGATTACGTATTGAAGAATCCTAAATCTTGTTATACCCCATC
ACTTACATGAGGAAAACATT

Downstream 100 bases:

>100_bases
CCAAAATATTGTTTTTATCTGCATCATTAAGAGTGTATTTAAGCTTCTTCACTCAAATGATGCAGRTTATGAGCATAAAA
TCTWACAGACTGAAAGTACT

Product: L-fucose permease

Products: Proton [Cytoplasm]; L-fucose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MNAKVLEKKFIVPFVLITSLFALWGFANDITNPMVAVFQTVMEIPASEAALVQLAFYGGYGTMAIPAALFASRYSYKAGI
LLGLALYAIGAFLFWPAAQYEIFNFFLVSLYILTFGLAFLETTANPYILAMGDPQTATRRLNFAQSFNPLGSITGMFVAS
QLVLTNLESDKRDAAGNLIFHTLSEAEKMSIRTHDLAEIRDPYIALGFVVVAVFIIIGLKKMPAVKIEEAGQISFKTAVS
RLAQKAKYREGVIAQAFYVGVQIMCWTFIVQYAERLGFTKAEGQNFNIIAMAIFISSRFISTALMKYLKAEFMLMLFAIG
GFLSILGVIFIDGVWGLYCLILTSGFMPLMFPTIYGIALYGLKEESTLGAAGLVMAIVGGALMPPLQGMIIDQGEVMGLP
AVNFSFILPLICFVVIAIYGFRAWKILK

Sequences:

>Translated_428_residues
MNAKVLEKKFIVPFVLITSLFALWGFANDITNPMVAVFQTVMEIPASEAALVQLAFYGGYGTMAIPAALFASRYSYKAGI
LLGLALYAIGAFLFWPAAQYEIFNFFLVSLYILTFGLAFLETTANPYILAMGDPQTATRRLNFAQSFNPLGSITGMFVAS
QLVLTNLESDKRDAAGNLIFHTLSEAEKMSIRTHDLAEIRDPYIALGFVVVAVFIIIGLKKMPAVKIEEAGQISFKTAVS
RLAQKAKYREGVIAQAFYVGVQIMCWTFIVQYAERLGFTKAEGQNFNIIAMAIFISSRFISTALMKYLKAEFMLMLFAIG
GFLSILGVIFIDGVWGLYCLILTSGFMPLMFPTIYGIALYGLKEESTLGAAGLVMAIVGGALMPPLQGMIIDQGEVMGLP
AVNFSFILPLICFVVIAIYGFRAWKILK
>Mature_428_residues
MNAKVLEKKFIVPFVLITSLFALWGFANDITNPMVAVFQTVMEIPASEAALVQLAFYGGYGTMAIPAALFASRYSYKAGI
LLGLALYAIGAFLFWPAAQYEIFNFFLVSLYILTFGLAFLETTANPYILAMGDPQTATRRLNFAQSFNPLGSITGMFVAS
QLVLTNLESDKRDAAGNLIFHTLSEAEKMSIRTHDLAEIRDPYIALGFVVVAVFIIIGLKKMPAVKIEEAGQISFKTAVS
RLAQKAKYREGVIAQAFYVGVQIMCWTFIVQYAERLGFTKAEGQNFNIIAMAIFISSRFISTALMKYLKAEFMLMLFAIG
GFLSILGVIFIDGVWGLYCLILTSGFMPLMFPTIYGIALYGLKEESTLGAAGLVMAIVGGALMPPLQGMIIDQGEVMGLP
AVNFSFILPLICFVVIAIYGFRAWKILK

Specific function: Transport of L-fucose into the cell

COG id: COG0738

COG function: function code G; Fucose permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family

Homologues:

Organism=Escherichia coli, GI1789166, Length=424, Percent_Identity=34.6698113207547, Blast_Score=245, Evalue=3e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FUCP_HAEIN (P44776)

Other databases:

- EMBL:   L42023
- PIR:   B64081
- RefSeq:   NP_438768.1
- ProteinModelPortal:   P44776
- GeneID:   950599
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0610
- NMPDR:   fig|71421.1.peg.579
- TIGR:   HI_0610
- HOGENOM:   HBG735535
- OMA:   SACMSLM
- ProtClustDB:   CLSK892373
- BioCyc:   HINF71421:HI_0610-MONOMER
- InterPro:   IPR005275
- InterPro:   IPR011701
- InterPro:   IPR016196
- TIGRFAMs:   TIGR00885

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 46989; Mature: 46989

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc72c344)-; HASH(0xbea72ec)-; HASH(0xc3de0bc)-; HASH(0xc935250)-; HASH(0xcfad860)-; HASH(0xcf1cf60)-; HASH(0xd41babc)-; HASH(0xbb6d834)-; HASH(0xcb0ab78)-; HASH(0xca490fc)-; HASH(0xcc0a3ac)-; HASH(0xbe833e4)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAKVLEKKFIVPFVLITSLFALWGFANDITNPMVAVFQTVMEIPASEAALVQLAFYGGY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHEEEEEECCC
GTMAIPAALFASRYSYKAGILLGLALYAIGAFLFWPAAQYEIFNFFLVSLYILTFGLAFL
CHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
ETTANPYILAMGDPQTATRRLNFAQSFNPLGSITGMFVASQLVLTNLESDKRDAAGNLIF
HHCCCCEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHH
HTLSEAEKMSIRTHDLAEIRDPYIALGFVVVAVFIIIGLKKMPAVKIEEAGQISFKTAVS
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHH
RLAQKAKYREGVIAQAFYVGVQIMCWTFIVQYAERLGFTKAEGQNFNIIAMAIFISSRFI
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHH
STALMKYLKAEFMLMLFAIGGFLSILGVIFIDGVWGLYCLILTSGFMPLMFPTIYGIALY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
GLKEESTLGAAGLVMAIVGGALMPPLQGMIIDQGEVMGLPAVNFSFILPLICFVVIAIYG
CCCCCCCCCHHHHHHHHHCCHHCCCCCCEEECCCCEECCCCCHHHHHHHHHHHHHHHHHH
FRAWKILK
HHHHEECH
>Mature Secondary Structure
MNAKVLEKKFIVPFVLITSLFALWGFANDITNPMVAVFQTVMEIPASEAALVQLAFYGGY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHEEEEEECCC
GTMAIPAALFASRYSYKAGILLGLALYAIGAFLFWPAAQYEIFNFFLVSLYILTFGLAFL
CHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
ETTANPYILAMGDPQTATRRLNFAQSFNPLGSITGMFVASQLVLTNLESDKRDAAGNLIF
HHCCCCEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHH
HTLSEAEKMSIRTHDLAEIRDPYIALGFVVVAVFIIIGLKKMPAVKIEEAGQISFKTAVS
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHH
RLAQKAKYREGVIAQAFYVGVQIMCWTFIVQYAERLGFTKAEGQNFNIIAMAIFISSRFI
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHH
STALMKYLKAEFMLMLFAIGGFLSILGVIFIDGVWGLYCLILTSGFMPLMFPTIYGIALY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
GLKEESTLGAAGLVMAIVGGALMPPLQGMIIDQGEVMGLPAVNFSFILPLICFVVIAIYG
CCCCCCCCCHHHHHHHHHCCHHCCCCCCEEECCCCEECCCCCHHHHHHHHHHHHHHHHHH
FRAWKILK
HHHHEECH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-fucose [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-fucose [Periplasm] = Proton [Cytoplasm] + L-fucose [Cytoplasm] [C]

General reaction: Permease [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800