Click here to switch to the map view.

The map label for this gene is fucA

Identifier: 16272553

GI number: 16272553

Start: 642776

End: 643426

Strand: Reverse

Name: fucA

Synonym: HI0611

Alternate gene names: 16272553

Gene position: 643426-642776 (Counterclockwise)

Preceding gene: 16272554

Following gene: 16272552

Centisome position: 35.16

GC content: 38.56

Gene sequence:

>651_bases
ATGAACAGAGCAGAATTATCACAAAAAATCATTGATACTTGCCTTGAAATGACAAAATTAGGTTTAAATCAAGGCACAGC
GGGAAACGTTAGTGTTCGTTATAAAGATGGAATGCTGATTACCCCGACAGGTATGCCATATCACTTAATGAAGACAGAAA
ATATTGTTTATGTTGATGGAAATGGCAAACACGAAGAAAATAAATTACCATCAAGCGAATGGCAATTTCACTTGAGTGTT
TATCATACTCGCCCTGAAGCAAATGCCGTTGTCCACAATCATTCCATTCACTGTGCAGGCTTATCCATTCTCGAAAAACC
TATTCCTGCAATTCATTACATGGTAGCCGTAAGCGGCACAGATCATATTCCTTGTGTACCTTATGCAACATTTGGTAGTC
ACAAATTAGCTAGTTATGTCGCAACGGGAATCAAAGAAAGCAAAGCCATTTTACTAGCACACCATGGTTTAATCACTTGC
GGAGAAAACCTAGATAAAGCCTTATGGCTCGCACAAGAAGTAGAAGTATTAGCGTCTTGGTATTTGAAATTACTCTCTAC
AGGCTTAGAAATTCCACTGCTCAGCAAAGAGCAAATGCAGGTAGTGTTAGGTAAATTCCACACCTATGGATTACGTATTG
AAGAATCCTAA

Upstream 100 bases:

>100_bases
GCTTATGCTGTTGTTGTCAGTGGTGAGATCGCAAAATATGGCAACATTATCATTAAAAAAGGGGTTACTCCCATTTTATA
AACAATAGAGGTACTACAAA

Downstream 100 bases:

>100_bases
ATCTTGTTATACCCCATCACTTACATGAGGAAAACATTATGAACGCCAAAGTTTTAGAAAAGAAATTCATCGTCCCCTTT
GTGCTTATTACTAGCTTATT

Product: L-fuculose phosphate aldolase

Products: NA

Alternate protein names: L-fuculose-1-phosphate aldolase

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MNRAELSQKIIDTCLEMTKLGLNQGTAGNVSVRYKDGMLITPTGMPYHLMKTENIVYVDGNGKHEENKLPSSEWQFHLSV
YHTRPEANAVVHNHSIHCAGLSILEKPIPAIHYMVAVSGTDHIPCVPYATFGSHKLASYVATGIKESKAILLAHHGLITC
GENLDKALWLAQEVEVLASWYLKLLSTGLEIPLLSKEQMQVVLGKFHTYGLRIEES

Sequences:

>Translated_216_residues
MNRAELSQKIIDTCLEMTKLGLNQGTAGNVSVRYKDGMLITPTGMPYHLMKTENIVYVDGNGKHEENKLPSSEWQFHLSV
YHTRPEANAVVHNHSIHCAGLSILEKPIPAIHYMVAVSGTDHIPCVPYATFGSHKLASYVATGIKESKAILLAHHGLITC
GENLDKALWLAQEVEVLASWYLKLLSTGLEIPLLSKEQMQVVLGKFHTYGLRIEES
>Mature_216_residues
MNRAELSQKIIDTCLEMTKLGLNQGTAGNVSVRYKDGMLITPTGMPYHLMKTENIVYVDGNGKHEENKLPSSEWQFHLSV
YHTRPEANAVVHNHSIHCAGLSILEKPIPAIHYMVAVSGTDHIPCVPYATFGSHKLASYVATGIKESKAILLAHHGLITC
GENLDKALWLAQEVEVLASWYLKLLSTGLEIPLLSKEQMQVVLGKFHTYGLRIEES

Specific function: Fucose metabolism; third step. [C]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. AraD/FucA subfamily

Homologues:

Organism=Escherichia coli, GI1789164, Length=215, Percent_Identity=64.6511627906977, Blast_Score=306, Evalue=9e-85,
Organism=Escherichia coli, GI1789094, Length=177, Percent_Identity=33.8983050847458, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790642, Length=124, Percent_Identity=33.8709677419355, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FUCA_HAEIN (P44777)

Other databases:

- EMBL:   L42023
- PIR:   C64081
- RefSeq:   NP_438769.1
- ProteinModelPortal:   P44777
- SMR:   P44777
- GeneID:   950000
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0611
- NMPDR:   fig|71421.1.peg.580
- TIGR:   HI_0611
- HOGENOM:   HBG541069
- OMA:   AVYEARP
- ProtClustDB:   PRK08087
- BioCyc:   HINF71421:HI_0611-MONOMER
- BRENDA:   4.1.2.17
- InterPro:   IPR001303
- InterPro:   IPR004782
- Gene3D:   G3DSA:3.40.225.10
- TIGRFAMs:   TIGR01086

Pfam domain/function: PF00596 Aldolase_II; SSF53639 Aldolase_II_N

EC number: =4.1.2.17

Molecular weight: Translated: 23944; Mature: 23944

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: ACT_SITE 73-73 ACT_SITE 113-113

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRAELSQKIIDTCLEMTKLGLNQGTAGNVSVRYKDGMLITPTGMPYHLMKTENIVYVDG
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCEEECCCCCCEEEEECCCEEEECC
NGKHEENKLPSSEWQFHLSVYHTRPEANAVVHNHSIHCAGLSILEKPIPAIHYMVAVSGT
CCCCCCCCCCCCCEEEEEEEEEECCCCCEEEECCEEEECCHHHHHCCCCCEEEEEEECCC
DHIPCVPYATFGSHKLASYVATGIKESKAILLAHHGLITCGENLDKALWLAQEVEVLASW
CCCCCCEECCCCCHHHHHHHHHCCCCCCEEEEEECCEEEECCCHHHHHHHHHHHHHHHHH
YLKLLSTGLEIPLLSKEQMQVVLGKFHTYGLRIEES
HHHHHHCCCCCEECCHHHHHHHHHHHHEEEEEEECC
>Mature Secondary Structure
MNRAELSQKIIDTCLEMTKLGLNQGTAGNVSVRYKDGMLITPTGMPYHLMKTENIVYVDG
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCEEECCCCCCEEEEECCCEEEECC
NGKHEENKLPSSEWQFHLSVYHTRPEANAVVHNHSIHCAGLSILEKPIPAIHYMVAVSGT
CCCCCCCCCCCCCEEEEEEEEEECCCCCEEEECCEEEECCHHHHHCCCCCEEEEEEECCC
DHIPCVPYATFGSHKLASYVATGIKESKAILLAHHGLITCGENLDKALWLAQEVEVLASW
CCCCCCEECCCCCHHHHHHHHHCCCCCCEEEEEECCEEEECCCHHHHHHHHHHHHHHHHH
YLKLLSTGLEIPLLSKEQMQVVLGKFHTYGLRIEES
HHHHHHCCCCCEECCHHHHHHHHHHHHEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800