Click here to switch to the map view.

The map label for this gene is gpsA [H]

Identifier: 16272547

GI number: 16272547

Start: 635766

End: 636773

Strand: Direct

Name: gpsA [H]

Synonym: HI0605

Alternate gene names: 16272547

Gene position: 635766-636773 (Clockwise)

Preceding gene: 16272546

Following gene: 16272548

Centisome position: 34.74

GC content: 42.26

Gene sequence:

>1008_bases
ATGATAACTTCGCAAACACCAATCACTGTGCTAGGTGCGGGATCTTATGGAACTGCGCTGGCAATTACCTTTTCTCGCAA
TGGTTCTCCCACTCACTTATGGGGGCACAATCCCGCCCATATCGCACAAATGCAGACAGAACGACAAAATTATCGTTTTT
TGCCGGATGTCATCTTTCCTGAGGATCTTCATTTAGAAAGTAATCTTGCACAAGCAATGGAATATTCTCAAGATATTTTA
ATCGTGGTGCCAAGCCATGCTTTCGGTGAAATTCTTATAAAAATCAAACCGCACTTAAAAGCCCATCACCGATTAATTTG
GGCAACAAAAGGTTTGGAACGTAACACAGGGCGTTTACTACAAACCGTAGTTGAAGAACAACTCGGAACGCAATATCCAC
TAGCTGTACTTTCTGGCCCAACTTTTGCAAAAGAATTAGCGCAAGGTCTACCATCAGCTATTACGCTTGCTGCCAATAAC
GAGCAATTCGCACGGGAATTTCAGTCTCGTATTCATTGTAGTAAAGGTTTCCGAGTTTATATAAATTCGGATATGACTGG
CGTTCAACTTGGTGGAGCAATTAAAAATGTGATCGCAATTGGTGCGGGTATTTCAGACGGTATGGGATTTGGCGCAAATG
CTCGCACAGCACTGATTACTCGAGGTATTGCAGAAATTACCCGCTTAGGTATCTCGCTCGGTGCAAATACCAATACATTT
ATGGGAATGTCTGGATTGGGCGATTTAGTGCTAACTTGCACCGATAATCAATCGCGCAATCGACGTTTTGGATTAATGCT
AGGTAAAGGATTAGATGCCCAAATGGCTATGGAAAATATCGGGCAAGTCGTAGAAGGTTTTTATAATACAAAAGAAGCCT
ATTTGCTTGCACAAAGACAAGGTGTGGAAATGCCGATTACAGAACAAATTTATCAAATGCTGTTTTGTGGCAAAAGCGCA
CAAGATGTAGCAATCAGCCTTTTGGGGCGAGCATGTAAAGGCGAATAA

Upstream 100 bases:

>100_bases
TTTAAATTCCGCCAAATGAATAAGTAATATTTTCCTGTGGTTGATAGGTTACCGAAAGATATCTATACTTATTTCCTCTT
TTACTAGATAAATTGTAGAT

Downstream 100 bases:

>100_bases
AAGGAGAAATTATGACATTAGATGTGTGGCAACATATTCGCCAAGAAGCCAAAGAACTTGCTGAAAACGAACCTATGCTT
GCTAGTTTTTTTCACTCTAC

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MITSQTPITVLGAGSYGTALAITFSRNGSPTHLWGHNPAHIAQMQTERQNYRFLPDVIFPEDLHLESNLAQAMEYSQDIL
IVVPSHAFGEILIKIKPHLKAHHRLIWATKGLERNTGRLLQTVVEEQLGTQYPLAVLSGPTFAKELAQGLPSAITLAANN
EQFAREFQSRIHCSKGFRVYINSDMTGVQLGGAIKNVIAIGAGISDGMGFGANARTALITRGIAEITRLGISLGANTNTF
MGMSGLGDLVLTCTDNQSRNRRFGLMLGKGLDAQMAMENIGQVVEGFYNTKEAYLLAQRQGVEMPITEQIYQMLFCGKSA
QDVAISLLGRACKGE

Sequences:

>Translated_335_residues
MITSQTPITVLGAGSYGTALAITFSRNGSPTHLWGHNPAHIAQMQTERQNYRFLPDVIFPEDLHLESNLAQAMEYSQDIL
IVVPSHAFGEILIKIKPHLKAHHRLIWATKGLERNTGRLLQTVVEEQLGTQYPLAVLSGPTFAKELAQGLPSAITLAANN
EQFAREFQSRIHCSKGFRVYINSDMTGVQLGGAIKNVIAIGAGISDGMGFGANARTALITRGIAEITRLGISLGANTNTF
MGMSGLGDLVLTCTDNQSRNRRFGLMLGKGLDAQMAMENIGQVVEGFYNTKEAYLLAQRQGVEMPITEQIYQMLFCGKSA
QDVAISLLGRACKGE
>Mature_335_residues
MITSQTPITVLGAGSYGTALAITFSRNGSPTHLWGHNPAHIAQMQTERQNYRFLPDVIFPEDLHLESNLAQAMEYSQDIL
IVVPSHAFGEILIKIKPHLKAHHRLIWATKGLERNTGRLLQTVVEEQLGTQYPLAVLSGPTFAKELAQGLPSAITLAANN
EQFAREFQSRIHCSKGFRVYINSDMTGVQLGGAIKNVIAIGAGISDGMGFGANARTALITRGIAEITRLGISLGANTNTF
MGMSGLGDLVLTCTDNQSRNRRFGLMLGKGLDAQMAMENIGQVVEGFYNTKEAYLLAQRQGVEMPITEQIYQMLFCGKSA
QDVAISLLGRACKGE

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI33695088, Length=339, Percent_Identity=27.7286135693215, Blast_Score=121, Evalue=9e-28,
Organism=Homo sapiens, GI24307999, Length=348, Percent_Identity=24.7126436781609, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1790037, Length=328, Percent_Identity=67.6829268292683, Blast_Score=468, Evalue=1e-133,
Organism=Caenorhabditis elegans, GI32564399, Length=334, Percent_Identity=26.0479041916168, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI193210136, Length=343, Percent_Identity=25.6559766763848, Blast_Score=104, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI32564403, Length=343, Percent_Identity=25.6559766763848, Blast_Score=103, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17507425, Length=349, Percent_Identity=22.3495702005731, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI193210134, Length=331, Percent_Identity=22.6586102719033, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320181, Length=341, Percent_Identity=28.1524926686217, Blast_Score=116, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6324513, Length=353, Percent_Identity=25.2124645892351, Blast_Score=111, Evalue=2e-25,
Organism=Drosophila melanogaster, GI22026922, Length=332, Percent_Identity=24.0963855421687, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI17136204, Length=340, Percent_Identity=25.8823529411765, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17136202, Length=340, Percent_Identity=25.8823529411765, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17136200, Length=340, Percent_Identity=25.8823529411765, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281362270, Length=237, Percent_Identity=28.2700421940928, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI45551945, Length=237, Percent_Identity=28.2700421940928, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24648969, Length=228, Percent_Identity=28.0701754385965, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 36394; Mature: 36394

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITSQTPITVLGAGSYGTALAITFSRNGSPTHLWGHNPAHIAQMQTERQNYRFLPDVIFP
CCCCCCCEEEEECCCCCCEEEEEEECCCCCCEECCCCHHHHHHHHHHCCCCEECCCCCCC
EDLHLESNLAQAMEYSQDILIVVPSHAFGEILIKIKPHLKAHHRLIWATKGLERNTGRLL
CCCCHHHHHHHHHHCCCCEEEEECCCCCEEEEEEECCCCCHHCEEEEEECCCCCCHHHHH
QTVVEEQLGTQYPLAVLSGPTFAKELAQGLPSAITLAANNEQFAREFQSRIHCSKGFRVY
HHHHHHHHCCCCCCCEECCCHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCCEEE
INSDMTGVQLGGAIKNVIAIGAGISDGMGFGANARTALITRGIAEITRLGISLGANTNTF
ECCCCCCEEHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCE
MGMSGLGDLVLTCTDNQSRNRRFGLMLGKGLDAQMAMENIGQVVEGFYNTKEAYLLAQRQ
EECCCCCCEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHEEEEHHC
GVEMPITEQIYQMLFCGKSAQDVAISLLGRACKGE
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MITSQTPITVLGAGSYGTALAITFSRNGSPTHLWGHNPAHIAQMQTERQNYRFLPDVIFP
CCCCCCCEEEEECCCCCCEEEEEEECCCCCCEECCCCHHHHHHHHHHCCCCEECCCCCCC
EDLHLESNLAQAMEYSQDILIVVPSHAFGEILIKIKPHLKAHHRLIWATKGLERNTGRLL
CCCCHHHHHHHHHHCCCCEEEEECCCCCEEEEEEECCCCCHHCEEEEEECCCCCCHHHHH
QTVVEEQLGTQYPLAVLSGPTFAKELAQGLPSAITLAANNEQFAREFQSRIHCSKGFRVY
HHHHHHHHCCCCCCCEECCCHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCCEEE
INSDMTGVQLGGAIKNVIAIGAGISDGMGFGANARTALITRGIAEITRLGISLGANTNTF
ECCCCCCEEHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCE
MGMSGLGDLVLTCTDNQSRNRRFGLMLGKGLDAQMAMENIGQVVEGFYNTKEAYLLAQRQ
EECCCCCCEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHEEEEHHC
GVEMPITEQIYQMLFCGKSAQDVAISLLGRACKGE
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA