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The map label for this gene is fadR [H]

Identifier: 16272374

GI number: 16272374

Start: 448763

End: 449488

Strand: Reverse

Name: fadR [H]

Synonym: HI0426

Alternate gene names: 16272374

Gene position: 449488-448763 (Counterclockwise)

Preceding gene: 16272377

Following gene: 16272372

Centisome position: 24.56

GC content: 35.54

Gene sequence:

>726_bases
ATGCAAAACAATAACGACATTTTAAAAGCCCAAAGTCCAGCAGCTTTAGCAGAGGAATATATTGTAAAGAGTATTTGGCA
AGATGTTTTTCCTGCGGGCAGTAATTTGCCATCAGAACGTGATTTAGCCGATAAGATTGGTGTAACTCGCACCACCCTAC
GTGAAGTTTTACAACGTTTGGCTCGTGATGGTTGGCTAACAATTCAGCACGGCAAACCCACCAAAGTAAATAATATTTGG
GATGCTGCAGGGCCGAATATTATTGAAACCTTAATTGCTTTGGATATGCAGTCTGCGCCCTTAATTATTGATAATATGCT
CTCTTTACGTAGTAAAATGTCGGAATCTTACATTTATGAAGCAGTAAAAAATTCCCCTCAAAAATCAACCGCACTTTTTG
CTGAATTAGAGCAATTACAAAACACAGCACAAGATTACACAGAATTTGATTACCAATTATTTCGTCAATTCACTGTTGTT
GCCAACAAACCCTTTTATCGTTTAATTTTCAATAGTTTAAAAGGCGTTTATCAGCGAATAGGGTTGTTATTTTTTAAAGA
AAAAAAACACCGTGAATTAACAAAGCAATTTTATTTAGAAATGCAACAAATTTGTCTTGAGGGAAATGCAGATGCAGTAG
TGGATTGCATCCGTAAACATAATTTACGTTCTTCAACCTATTGGAAAGCCATTTTAGAACGATTGCCACAAAATTTATCA
GATTAA

Upstream 100 bases:

>100_bases
GCGAACATTGTAATATATCCCCCTTTAAAGGATAATAAAAACCAAGTAATTTTTTTATAAAATTGCATTTTTTTTGATTT
TTATCTGATTTTTAATTGTA

Downstream 100 bases:

>100_bases
TACTGGAAGCGAATTTAAGAAAAAATATAAAACTTTTCTTATAATTACAGAATCATTTTCACCAATTTATCTGCTTTAAT
TCGTGCAAATTTTTTCAAAA

Product: fatty acid metabolism regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MQNNNDILKAQSPAALAEEYIVKSIWQDVFPAGSNLPSERDLADKIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNNIW
DAAGPNIIETLIALDMQSAPLIIDNMLSLRSKMSESYIYEAVKNSPQKSTALFAELEQLQNTAQDYTEFDYQLFRQFTVV
ANKPFYRLIFNSLKGVYQRIGLLFFKEKKHRELTKQFYLEMQQICLEGNADAVVDCIRKHNLRSSTYWKAILERLPQNLS
D

Sequences:

>Translated_241_residues
MQNNNDILKAQSPAALAEEYIVKSIWQDVFPAGSNLPSERDLADKIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNNIW
DAAGPNIIETLIALDMQSAPLIIDNMLSLRSKMSESYIYEAVKNSPQKSTALFAELEQLQNTAQDYTEFDYQLFRQFTVV
ANKPFYRLIFNSLKGVYQRIGLLFFKEKKHRELTKQFYLEMQQICLEGNADAVVDCIRKHNLRSSTYWKAILERLPQNLS
D
>Mature_241_residues
MQNNNDILKAQSPAALAEEYIVKSIWQDVFPAGSNLPSERDLADKIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNNIW
DAAGPNIIETLIALDMQSAPLIIDNMLSLRSKMSESYIYEAVKNSPQKSTALFAELEQLQNTAQDYTEFDYQLFRQFTVV
ANKPFYRLIFNSLKGVYQRIGLLFFKEKKHRELTKQFYLEMQQICLEGNADAVVDCIRKHNLRSSTYWKAILERLPQNLS
D

Specific function: Multifunctional regulator of fatty acid metabolism [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787436, Length=234, Percent_Identity=47.4358974358974, Blast_Score=243, Evalue=9e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014178
- InterPro:   IPR008920
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07840 FadR_C; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 27764; Mature: 27764

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNNNDILKAQSPAALAEEYIVKSIWQDVFPAGSNLPSERDLADKIGVTRTTLREVLQRL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHH
ARDGWLTIQHGKPTKVNNIWDAAGPNIIETLIALDMQSAPLIIDNMLSLRSKMSESYIYE
HHCCCEEEECCCCCCCCCCHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
AVKNSPQKSTALFAELEQLQNTAQDYTEFDYQLFRQFTVVANKPFYRLIFNSLKGVYQRI
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GLLFFKEKKHRELTKQFYLEMQQICLEGNADAVVDCIRKHNLRSSTYWKAILERLPQNLS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
D
C
>Mature Secondary Structure
MQNNNDILKAQSPAALAEEYIVKSIWQDVFPAGSNLPSERDLADKIGVTRTTLREVLQRL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHH
ARDGWLTIQHGKPTKVNNIWDAAGPNIIETLIALDMQSAPLIIDNMLSLRSKMSESYIYE
HHCCCEEEECCCCCCCCCCHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
AVKNSPQKSTALFAELEQLQNTAQDYTEFDYQLFRQFTVVANKPFYRLIFNSLKGVYQRI
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GLLFFKEKKHRELTKQFYLEMQQICLEGNADAVVDCIRKHNLRSSTYWKAILERLPQNLS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
D
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA; DNA [C]

Specific reaction: Activates transcription of at least two genes required for unsaturated fatty acid biosynthesis; activates the iclR gene encoding the transcription regulator of the aceBAKoperon which in turn encodes the glyoxylate shunt enzymes Protein + DNA = Protein-DN

General reaction: NA

Inhibitor: Fatty acyl CoA compounds [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA