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The map label for this gene is fadL

Identifier: 16272350

GI number: 16272350

Start: 422144

End: 423523

Strand: Direct

Name: fadL

Synonym: HI0401

Alternate gene names: 16272350

Gene position: 422144-423523 (Clockwise)

Preceding gene: 16272348

Following gene: 16272351

Centisome position: 23.07

GC content: 38.55

Gene sequence:

>1380_bases
ATGAAAAAATTTAATCAATCTCTATTAGCAACAGCAATGTTGTTGGCTGCAGGTGGTGCAAATGCGGCGGCTTTCCAATT
GGCGGAAGTTTCTACTTCTGGGCTTGGTCGTGCCTATGCAGGTGAAGCGGCGATTGCAGATAATGCTTCTGTCGTGGCAA
CTAACCCAGCTTTGATGAGTTTATTTAAAACGGCACAGTTTTCCACGGGTGGCGTTTATGTTGATTCTAGAATTAATATG
AATGGTGATGTAACTTCTCATGCTACAATAATAACATCAAGTAGTGGAATTAAAGCAATAGAGGGCGGCTCAGCTTCAGC
GCGTAATGTTGTTCCTGGTGCTTTTGTGCCAAATCTTTATTTCGTTGCACCAGTGAATGATAAATTCGCGCTGGGTGCAG
GAATGAATGTCAATTTCGGTCTAAAAAGTGAATATGACGATAGTTATGATGCTGGTATATTTGGTGGAAAAACTGACTTG
AGTGCTATCAACTTAAATTTAAGTGGTGCTTATCGAGTAACAGAAGGCTTGAGCCTAGGTTTAGGGGTAAATGCAGTTTA
TGCTAAAGCCCAAGTTGAACGGAATGCTGGTATTATTGCGGATAGTGTTAAGGATAACCAAGTAAAAACTGCACTCACAG
TACAGCAAGAACCACTCAAATTTCTTGATAAGTATTTGCCCTCTAAAGACACATCTGTTGTGTCATTACAAGATAGAGCA
GCTTGGGGCTTTGGCTGGAATGCAGGTGTAATGTATCAATTTAATGAAGCTAACAGAATTGGTTTAGCCTATCATTCTAA
AGTGGACATTGATTTTACTGACCGCACTGCCACTAGTGTAGAAGCAAATGTTATCAAGGCAGGTAAAAAAGGTGATTTAA
CCCTTACATTGCCAGATTACTTAGAACTTTCTGGTTTCCATCAATTAACTGACAAACTTGCTGTGCATTATAGTTATAAA
TATACCCATTGGAGTCGTTTAACAAAATTAAACGCTAGCTTCGAAGATGGTAAAAAAGCTTTTGATAAAGAATTACAATA
CAGTAATAACTCTCGTGTTGCATTAGGGGCAAGTTATAATCTTGATGAAAAATTGACCTTACGTGCGGGTATTGCTTACG
ATCAGGCTGCATCTCGTCATCAGCGTAGTGCTGCAATTCCAGATACCGATCGCACTTGGTATAGTTTAGGGGCAACCTAT
AAATTCACGCCGAATTTATCTGTTGATCTTGGCTATGCTTACTTAAAAGGCAAAAAAGTTCACTTTAAAGAAGTAAAAAC
AATAGGTGACGAACGTTCACTTACATTGAATACAACTGCAAATTATACTTCTCAAGCACATGCAAATCTTTACGGTTTAA
ACTTAAATTATAGTTTCTAA

Upstream 100 bases:

>100_bases
TAACTAGTCGTAGCTCTAATAAAAATAAGGAATAGAGTTGCACTCAATAGATTCGGGCTTTATAATTGCCCAGATTTTTA
TTTATAACAAAGGGTTCCAA

Downstream 100 bases:

>100_bases
TCCGTTAAAAAATTTAGCATAATAAAGCACACTTCCACACCAAGTGTGCTTTTCTTTTTATAAAACAAGGCGAAAAATGA
CCGCACTTTATTACACTTAT

Product: long-chain fatty acid transport protein

Products: NA

Alternate protein names: OMP P1

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MKKFNQSLLATAMLLAAGGANAAAFQLAEVSTSGLGRAYAGEAAIADNASVVATNPALMSLFKTAQFSTGGVYVDSRINM
NGDVTSHATIITSSSGIKAIEGGSASARNVVPGAFVPNLYFVAPVNDKFALGAGMNVNFGLKSEYDDSYDAGIFGGKTDL
SAINLNLSGAYRVTEGLSLGLGVNAVYAKAQVERNAGIIADSVKDNQVKTALTVQQEPLKFLDKYLPSKDTSVVSLQDRA
AWGFGWNAGVMYQFNEANRIGLAYHSKVDIDFTDRTATSVEANVIKAGKKGDLTLTLPDYLELSGFHQLTDKLAVHYSYK
YTHWSRLTKLNASFEDGKKAFDKELQYSNNSRVALGASYNLDEKLTLRAGIAYDQAASRHQRSAAIPDTDRTWYSLGATY
KFTPNLSVDLGYAYLKGKKVHFKEVKTIGDERSLTLNTTANYTSQAHANLYGLNLNYSF

Sequences:

>Translated_459_residues
MKKFNQSLLATAMLLAAGGANAAAFQLAEVSTSGLGRAYAGEAAIADNASVVATNPALMSLFKTAQFSTGGVYVDSRINM
NGDVTSHATIITSSSGIKAIEGGSASARNVVPGAFVPNLYFVAPVNDKFALGAGMNVNFGLKSEYDDSYDAGIFGGKTDL
SAINLNLSGAYRVTEGLSLGLGVNAVYAKAQVERNAGIIADSVKDNQVKTALTVQQEPLKFLDKYLPSKDTSVVSLQDRA
AWGFGWNAGVMYQFNEANRIGLAYHSKVDIDFTDRTATSVEANVIKAGKKGDLTLTLPDYLELSGFHQLTDKLAVHYSYK
YTHWSRLTKLNASFEDGKKAFDKELQYSNNSRVALGASYNLDEKLTLRAGIAYDQAASRHQRSAAIPDTDRTWYSLGATY
KFTPNLSVDLGYAYLKGKKVHFKEVKTIGDERSLTLNTTANYTSQAHANLYGLNLNYSF
>Mature_459_residues
MKKFNQSLLATAMLLAAGGANAAAFQLAEVSTSGLGRAYAGEAAIADNASVVATNPALMSLFKTAQFSTGGVYVDSRINM
NGDVTSHATIITSSSGIKAIEGGSASARNVVPGAFVPNLYFVAPVNDKFALGAGMNVNFGLKSEYDDSYDAGIFGGKTDL
SAINLNLSGAYRVTEGLSLGLGVNAVYAKAQVERNAGIIADSVKDNQVKTALTVQQEPLKFLDKYLPSKDTSVVSLQDRA
AWGFGWNAGVMYQFNEANRIGLAYHSKVDIDFTDRTATSVEANVIKAGKKGDLTLTLPDYLELSGFHQLTDKLAVHYSYK
YTHWSRLTKLNASFEDGKKAFDKELQYSNNSRVALGASYNLDEKLTLRAGIAYDQAASRHQRSAAIPDTDRTWYSLGATY
KFTPNLSVDLGYAYLKGKKVHFKEVKTIGDERSLTLNTTANYTSQAHANLYGLNLNYSF

Specific function: Involved In Translocation Of Long-Chain Fatty Acids Across The Outer Membrane. It Is A Receptor For The Bacteriophage T2. FADl May Form A Specific Channel. [C]

COG id: COG2067

COG function: function code I; Long-chain fatty acid transport protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ompP1/fadL family

Homologues:

Organism=Escherichia coli, GI145693163, Length=470, Percent_Identity=40, Blast_Score=323, Evalue=1e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OPP11_HAEIN (P43838)

Other databases:

- EMBL:   L42023
- PIR:   F64065
- RefSeq:   NP_438563.1
- ProteinModelPortal:   P43838
- SMR:   P43838
- GeneID:   949945
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0401
- NMPDR:   fig|71421.1.peg.376
- TIGR:   HI_0401
- HOGENOM:   HBG576860
- OMA:   DQDRLWL
- ProtClustDB:   CLSK892368
- BioCyc:   HINF71421:HI_0401-MONOMER
- InterPro:   IPR011250
- InterPro:   IPR005017
- Gene3D:   G3DSA:2.40.160.20

Pfam domain/function: PF03349 Toluene_X

EC number: NA

Molecular weight: Translated: 49478; Mature: 49478

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKFNQSLLATAMLLAAGGANAAAFQLAEVSTSGLGRAYAGEAAIADNASVVATNPALMS
CCHHHHHHHHHHHHHHCCCCCHHEEEEEECCCCCCCCCCCCCEEECCCCEEEEECHHHHH
LFKTAQFSTGGVYVDSRINMNGDVTSHATIITSSSGIKAIEGGSASARNVVPGAFVPNLY
HHHHHCCCCCCEEEEEEECCCCCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCCEE
FVAPVNDKFALGAGMNVNFGLKSEYDDSYDAGIFGGKTDLSAINLNLSGAYRVTEGLSLG
EEEECCCCEEECCCCEECCCCCCCCCCCCCCCEECCCCCCEEEEEECCCCEEEECCCEEC
LGVNAVYAKAQVERNAGIIADSVKDNQVKTALTVQQEPLKFLDKYLPSKDTSVVSLQDRA
CCCEEEEEEEEECCCCCEEEECCCCCCEEEEEEECHHHHHHHHHHCCCCCCEEEEEECCC
AWGFGWNAGVMYQFNEANRIGLAYHSKVDIDFTDRTATSVEANVIKAGKKGDLTLTLPDY
EECCCCCCCEEEEECCCCEEEEEEECEEEEEECCCCCCCEEEEEEECCCCCCEEEECCHH
LELSGFHQLTDKLAVHYSYKYTHWSRLTKLNASFEDGKKAFDKELQYSNNSRVALGASYN
HHHCCHHHHHHCEEEEEEEEEEHHHHHHEECCCHHHHHHHHHHHHCCCCCCEEEEEECCC
LDEKLTLRAGIAYDQAASRHQRSAAIPDTDRTWYSLGATYKFTPNLSVDLGYAYLKGKKV
CCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCEEEECCEEEECCCCEEEECEEEEECCEE
HFKEVKTIGDERSLTLNTTANYTSQAHANLYGLNLNYSF
EHHHHHHCCCCCEEEEECCCCCCCCCCCEEEEEEEEECC
>Mature Secondary Structure
MKKFNQSLLATAMLLAAGGANAAAFQLAEVSTSGLGRAYAGEAAIADNASVVATNPALMS
CCHHHHHHHHHHHHHHCCCCCHHEEEEEECCCCCCCCCCCCCEEECCCCEEEEECHHHHH
LFKTAQFSTGGVYVDSRINMNGDVTSHATIITSSSGIKAIEGGSASARNVVPGAFVPNLY
HHHHHCCCCCCEEEEEEECCCCCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCCEE
FVAPVNDKFALGAGMNVNFGLKSEYDDSYDAGIFGGKTDLSAINLNLSGAYRVTEGLSLG
EEEECCCCEEECCCCEECCCCCCCCCCCCCCCEECCCCCCEEEEEECCCCEEEECCCEEC
LGVNAVYAKAQVERNAGIIADSVKDNQVKTALTVQQEPLKFLDKYLPSKDTSVVSLQDRA
CCCEEEEEEEEECCCCCEEEECCCCCCEEEEEEECHHHHHHHHHHCCCCCCEEEEEECCC
AWGFGWNAGVMYQFNEANRIGLAYHSKVDIDFTDRTATSVEANVIKAGKKGDLTLTLPDY
EECCCCCCCEEEEECCCCEEEEEEECEEEEEECCCCCCCEEEEEEECCCCCCEEEECCHH
LELSGFHQLTDKLAVHYSYKYTHWSRLTKLNASFEDGKKAFDKELQYSNNSRVALGASYN
HHHCCHHHHHHCEEEEEEEEEEHHHHHHEECCCHHHHHHHHHHHHCCCCCCEEEEEECCC
LDEKLTLRAGIAYDQAASRHQRSAAIPDTDRTWYSLGATYKFTPNLSVDLGYAYLKGKKV
CCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCEEEECCEEEECCCCEEEECEEEEECCEE
HFKEVKTIGDERSLTLNTTANYTSQAHANLYGLNLNYSF
EHHHHHHCCCCCEEEEECCCCCCCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023