Click here to switch to the map view.

The map label for this gene is hscB

Identifier: 16272323

GI number: 16272323

Start: 397817

End: 398341

Strand: Reverse

Name: hscB

Synonym: HI0375

Alternate gene names: 16272323

Gene position: 398341-397817 (Counterclockwise)

Preceding gene: 16272324

Following gene: 16272322

Centisome position: 21.77

GC content: 34.67

Gene sequence:

>525_bases
ATGTTCAATCCTTTTCAAATTTTTGATTTGCCAGTTGATTTTCAGCTGGATGAAAAAGTACTAAATGCACGTTATTTAAA
ATTACAAAAGGCCCTACATCCAGATAATTTTGTCTCAAGTAATGCTTTAGATCAACGTGTTGCGATGCAAAAATCTACCG
AAGTGAATGATGCCTTAAAAACGTTAAAAGACCCAATTTTGCGAGCTGAAGCGATCATTGCTCTTAATACTGGTGAGCAG
TTAGATCTTGAACAAAAAAGCACGCAAGATGTGGCGTTTTTAATGCAACAATTACAATGGCGCGAACAATTAGAAGAAGT
TGAACGCCAGCAAGATGAAAGAGCATTAAATGCTTTTGCTAAAGAAATTAAACAAGAAACTCAATCATTATTGACCGCAC
TTTTTGAGAGTTTGAAATCTCAACAATGGGCGAGAGCATCTCAATACTGTGATAAATTACGTTTTACCCATAAACTTTCT
GAAGAAATTGAACGTGTGGAAGAACGAATTTTTGAATTAGATTAA

Upstream 100 bases:

>100_bases
TGTAAAAGAAGGCCTAAATGAAGGCTTTAAATATAATAATCCAAATGTAAAAGAATCTTGTGGTTGTGGCGAAAGTTTCC
ACGTTTAAGGTAATAATCTG

Downstream 100 bases:

>100_bases
ATGTGGGGGCAAATGTAATTTGCCCCTACGAGATGTGAATAAATAACACTATGCAAACTCTTGAACAGCTCACTAGCCCA
GAACATTCTGCTTGGATAAC

Product: co-chaperone HscB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MFNPFQIFDLPVDFQLDEKVLNARYLKLQKALHPDNFVSSNALDQRVAMQKSTEVNDALKTLKDPILRAEAIIALNTGEQ
LDLEQKSTQDVAFLMQQLQWREQLEEVERQQDERALNAFAKEIKQETQSLLTALFESLKSQQWARASQYCDKLRFTHKLS
EEIERVEERIFELD

Sequences:

>Translated_174_residues
MFNPFQIFDLPVDFQLDEKVLNARYLKLQKALHPDNFVSSNALDQRVAMQKSTEVNDALKTLKDPILRAEAIIALNTGEQ
LDLEQKSTQDVAFLMQQLQWREQLEEVERQQDERALNAFAKEIKQETQSLLTALFESLKSQQWARASQYCDKLRFTHKLS
EEIERVEERIFELD
>Mature_174_residues
MFNPFQIFDLPVDFQLDEKVLNARYLKLQKALHPDNFVSSNALDQRVAMQKSTEVNDALKTLKDPILRAEAIIALNTGEQ
LDLEQKSTQDVAFLMQQLQWREQLEEVERQQDERALNAFAKEIKQETQSLLTALFESLKSQQWARASQYCDKLRFTHKLS
EEIERVEERIFELD

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain

Homologues:

Organism=Escherichia coli, GI1788876, Length=169, Percent_Identity=37.8698224852071, Blast_Score=119, Evalue=9e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSCB_HAEIN (Q57006)

Other databases:

- EMBL:   L42023
- PIR:   D64150
- RefSeq:   NP_438536.1
- ProteinModelPortal:   Q57006
- SMR:   Q57006
- GeneID:   949448
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0375
- NMPDR:   fig|71421.1.peg.349
- TIGR:   HI_0375
- HOGENOM:   HBG751004
- OMA:   LNDAYQT
- ProtClustDB:   PRK01773
- BioCyc:   HINF71421:HI_0375-MONOMER
- HAMAP:   MF_00682
- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640
- Gene3D:   G3DSA:1.10.287.110
- Gene3D:   G3DSA:1.20.1280.20
- SMART:   SM00271
- TIGRFAMs:   TIGR00714

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C; SSF46565 DnaJ_N; SSF47144 HSC20_C

EC number: NA

Molecular weight: Translated: 20431; Mature: 20431

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS00636 DNAJ_1; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNPFQIFDLPVDFQLDEKVLNARYLKLQKALHPDNFVSSNALDQRVAMQKSTEVNDALK
CCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TLKDPILRAEAIIALNTGEQLDLEQKSTQDVAFLMQQLQWREQLEEVERQQDERALNAFA
HHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEIKQETQSLLTALFESLKSQQWARASQYCDKLRFTHKLSEEIERVEERIFELD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFNPFQIFDLPVDFQLDEKVLNARYLKLQKALHPDNFVSSNALDQRVAMQKSTEVNDALK
CCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TLKDPILRAEAIIALNTGEQLDLEQKSTQDVAFLMQQLQWREQLEEVERQQDERALNAFA
HHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEIKQETQSLLTALFESLKSQQWARASQYCDKLRFTHKLSEEIERVEERIFELD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800