Click here to switch to the map view.

The map label for this gene is djlA

Identifier: 16272229

GI number: 16272229

Start: 304808

End: 305674

Strand: Reverse

Name: djlA

Synonym: HI0271

Alternate gene names: 16272229

Gene position: 305674-304808 (Counterclockwise)

Preceding gene: 16272230

Following gene: 16272228

Centisome position: 16.7

GC content: 39.33

Gene sequence:

>867_bases
ATGGAATTTATTGGAAAAATTATAGGCGTATTTTTAGGTTGGAAAGTTGGTGGATTTTTTGGTGCGATTGCTGGTCTCAT
TTTAGGCTCTATTGCAGATAAAAAATTGTATGAACTTGGCTCGGTAAGTTCTAGTTTCTTTAAAAAGAAAACAACGCGTC
AAGACTTGTTTATGCAAACCTCCTTTGCGGTGTTAGGGCATTTAAGCAAATCGAAAGGGCGTGTAACAGAAGAAGATATC
CAATTAGCTAATCAATTAATGATTCAGCTTAAACTGGATGATGCTGGGCGTAAATTAGCGCAAGATGCGTTTCGTCGTGG
TAAAGAATCTGATTTCCCGATTCGTCAAGTTATCCGTGAATTTCGCATTGGTTGTGGGCAACGTGCTGATTTATTGAGAA
TGTTCTTACAAGTGCAAGTTCAAGCAGCTTTTGCCGATTCAGAACTTCACGAAAATGAGAAAGAAGTGCTTTATGTGATC
GCTGAAGAACTTGGTCTTTCTCGTATGCAATTTGAACAAATGATTGCGATGGAAATGGCTGCTCGAGCTTTTACTCAAGG
CGGTTTTTATCAGAAATATCAACAAGGTGCCTATCAAGGTGGCTACCAATATCAACAACAAAATAGTGGTGGTTACCAAC
ATGCTTCAGGCCCAACTTTAAATGATGCCTATAAAGTATTGGGTGTGACTGAGTCCGACGAGCAAAGCACGGTTAAGCGT
GCTTATCGTCGTTTAATGAATGAACATCATCCAGATAAACTTGTGGCGAAAGGTTTACCGCCAGAAATGATGGAAATGGC
AAAAGAAAAAACTCAACAGATTCAAGCCGCTTACGATTTAATTTGTAAAGCAAAAGGCTGGAAATAG

Upstream 100 bases:

>100_bases
TCGTGCCGAATTTGGCGTATAAAACTTGAGAAATAAATTTTTATCATCATTATAAATAACATTATAAAAATAACCGCACT
TTGACTTAACAGAGGAAAGA

Downstream 100 bases:

>100_bases
TGCGTGTTATTCTTGCGCCTATGCAAGGGGTTTTAGATCCCTTTGTACGTGAACTTCTCACCGAAGTGAATGACTACGAT
TTATGTATAACAGAATTTGT

Product: Dna-J like membrane chaperone protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MEFIGKIIGVFLGWKVGGFFGAIAGLILGSIADKKLYELGSVSSSFFKKKTTRQDLFMQTSFAVLGHLSKSKGRVTEEDI
QLANQLMIQLKLDDAGRKLAQDAFRRGKESDFPIRQVIREFRIGCGQRADLLRMFLQVQVQAAFADSELHENEKEVLYVI
AEELGLSRMQFEQMIAMEMAARAFTQGGFYQKYQQGAYQGGYQYQQQNSGGYQHASGPTLNDAYKVLGVTESDEQSTVKR
AYRRLMNEHHPDKLVAKGLPPEMMEMAKEKTQQIQAAYDLICKAKGWK

Sequences:

>Translated_288_residues
MEFIGKIIGVFLGWKVGGFFGAIAGLILGSIADKKLYELGSVSSSFFKKKTTRQDLFMQTSFAVLGHLSKSKGRVTEEDI
QLANQLMIQLKLDDAGRKLAQDAFRRGKESDFPIRQVIREFRIGCGQRADLLRMFLQVQVQAAFADSELHENEKEVLYVI
AEELGLSRMQFEQMIAMEMAARAFTQGGFYQKYQQGAYQGGYQYQQQNSGGYQHASGPTLNDAYKVLGVTESDEQSTVKR
AYRRLMNEHHPDKLVAKGLPPEMMEMAKEKTQQIQAAYDLICKAKGWK
>Mature_288_residues
MEFIGKIIGVFLGWKVGGFFGAIAGLILGSIADKKLYELGSVSSSFFKKKTTRQDLFMQTSFAVLGHLSKSKGRVTEEDI
QLANQLMIQLKLDDAGRKLAQDAFRRGKESDFPIRQVIREFRIGCGQRADLLRMFLQVQVQAAFADSELHENEKEVLYVI
AEELGLSRMQFEQMIAMEMAARAFTQGGFYQKYQQGAYQGGYQYQQQNSGGYQHASGPTLNDAYKVLGVTESDEQSTVKR
AYRRLMNEHHPDKLVAKGLPPEMMEMAKEKTQQIQAAYDLICKAKGWK

Specific function: Regulatory dnaK co-chaperone. Direct interaction between dnaK and djlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the rcsB/rcsC phosphotransfer sig

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cell inner membrane; Single-pass type III membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain

Homologues:

Organism=Escherichia coli, GI1786241, Length=289, Percent_Identity=52.2491349480969, Blast_Score=274, Evalue=6e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DJLA_HAEIN (P44607)

Other databases:

- EMBL:   L42023
- PIR:   G64146
- RefSeq:   NP_438440.1
- ProteinModelPortal:   P44607
- SMR:   P44607
- GeneID:   949410
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0271
- NMPDR:   fig|71421.1.peg.256
- TIGR:   HI_0271
- HOGENOM:   HBG508481
- OMA:   LRACWRM
- ProtClustDB:   PRK09430
- BioCyc:   HINF71421:HI_0271-MONOMER
- HAMAP:   MF_01153
- InterPro:   IPR001623
- InterPro:   IPR007791
- InterPro:   IPR015609
- InterPro:   IPR003095
- Gene3D:   G3DSA:1.10.287.110
- PANTHER:   PTHR11821
- PRINTS:   PR00625
- SMART:   SM00271

Pfam domain/function: PF00226 DnaJ; PF05099 TerB; SSF46565 DnaJ_N

EC number: NA

Molecular weight: Translated: 32524; Mature: 32524

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS00636 DNAJ_1; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc79cb04)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCH
>Mature Secondary Structure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HHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800