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The map label for this gene is hxuC [H]

Identifier: 16272220

GI number: 16272220

Start: 292279

End: 294450

Strand: Direct

Name: hxuC [H]

Synonym: HI0262

Alternate gene names: 16272220

Gene position: 292279-294450 (Clockwise)

Preceding gene: 16272219

Following gene: 16272221

Centisome position: 15.97

GC content: 38.21

Gene sequence:

>2172_bases
ATGCGATTTTCTAAACTTTCCCTTGCAATTACAACAACCTTAGTGACAGCAAATGCGCTAGCGCAATCCGTTGAATTAGA
CTCTATCAACGTTATTGCGACACGAGATCCAAGTAGGTTTGCTTATACGCCAGAAAAACAATCTAAAGATAGTCTTCTTT
CTAAGCAAGCGACTAGTGTTGCAGATGCGTTAGAAGACATTCCCAATGTTGATGTTAGAGGCGGTTCGAGAAGCATTGCT
CAAAAACCTAATATTCGAGGGTTAAGTGATAATCGTGTTGTGCAAGTCATTGATGGCGTGAGACAAAATTTTGATTTAGC
ACATAGAGGTTCTTATTTTCTTCCAATGTCACTCATCCAAGAAATTGAAGTAATCAAAGGACCAAGTAGCTCCTTATGGG
GTAGCGGTGCATTGGGTGGTGTTGTGGCAATGCGTACGCCAAATGCTTTAGACTTATTGAAAAATAATGACAAATTCGGA
GTTAAAATTCGCCAAGGTTATCAAACTGCTAATAATTTATCGGAAAAGGATGTTTCTGTATTTGCGGCAAATGACAAATT
CGATGTTCTTATTAGTGGTTTCTATAATAATGCGGATAATTTACGCACTGGTAAAGGCAACAAGCTAAATAATACCGCCT
ATAAACAGTTTGGGGGCTTAGCAAAATTCGGTTGGCAAATTAATGATGCGAACCGCGTGGAATTATCCCACCGCGAAACT
CGTTTTAAACAAACAGCACCAAGCAATAATGAGGTGGAAAACGAACTTACTAATGAACAAATTACAGATCAAATCAAAAA
GTTCCACGGACAAAAAGACGATCTTCTTCCTCCTACAACACAACCATCACCATCAGAAAGATCAGAGTTTTACTCTAAAG
TGAAAACACGTTTAGGTAGTGTCAGTTATTTAACTGATCAACAAATTCCTGATCAAAGCACGGTATTTAACTATTATTTA
ACGCCAGATAATCCTTATCTAAATACGCATATCGCACTGTATAACAATAAAACTATTGAGAAAGAACAGCGTAAAGTCAG
TGGTGTGAAAGATCAGACTAAATTGACTACCCGAGGTATAAATTTACGTAATTCTTCCGAATTATCTCACATTTCCTTTG
TTTATGGGGTGGATTATATGCGAGATAAAATCCGTACCGAACGAGGCACAAACGGTAGCGATGCGAAGTTTCGAGCGGAC
CCCTATAATGCGAATTCAAACACTACAGGCGTTTATTTAATCGCCCATATTCCGCTATTTGGGGAAAAATTGCTAGTTTC
GCCAAGTGTACGTTATGACCACTACGATACCTCAAGTAAAACCGTAAAATACAAGGATAATCATTTATCTCCTGCCACAA
AATTAACTTGGATAGTGACCAATTGGTTAGATTTTACTGCCAAATATAATGAAGCTTTCCGAGCACCATCTATGCAAGAG
CGATTTGTGAGTGGTGCTCACTTTGGGGCAAATACTCTAGGGCTAGATCACATCAATAGATTTGTAGCAAATCCAAATTT
GCGCCCTGAAACAGCGAAAAATAAAGAAATTACCGCAAATCTACATTTTGATAGTCTGTTTAAACAAGGCGATAAATTCA
AAATTGAAGCGACTTATTTCCGTAATGATGTGAAAGATTTTATTAACTTAAAAATATTTAATGATGCAAAGACAAGTGCA
AGTGCAGGTGCAAATCCAAATACAAATGGAGCATTGTTGCCAAAAAATTCCCAGTATCAAAACATAACTAATGCCCGTTT
AAGCGGTATTGAATTGCAAGCTCAATACCAAACAGAACGTTTAACGCTATTTACTAACTATGGCAGCACCAAAGGTAAAG
ATAAAGATAGTGGCGAAGCTTTATCAAACATTGCCGCAAGCAAAATCGGCGTAGGGGTAAATTATGCTTTAGTAAAAGAC
AAATTCACGGTGGGAGCGACAGTAACCCATTACGCTGCTCAACGCCGAGTGCCTAAAGATCATAGTGTTACCTACCCAAG
TTATATACTGACCGATCTTCGTGCTACCTATGCACCATTAAAAGGCGAATGGAAAAACCTGCGTTTAGATTTTGCACTGG
AAAACTTGTTTGATAGAAAATATCAACCCGCGTTTAGTTTAATGGAAGGCACTGGTCGTAATGCGAAAATTAGTGCGGTT
TATAGCTTCTAA

Upstream 100 bases:

>100_bases
AAATTCAAATGATTATAAATAAACCAATTGATTATTATTATTATTATTATTATTATTATCGCCATTCTCCTCTTTTTAAT
TATTACAATAAGGAAAACAG

Downstream 100 bases:

>100_bases
ATTTACTTTGGAAAACGCCCTAAAGCTGTTTTCCCTCAATTTTTGTAATTTTATCAATTAATAGGACATAAGGAATGAAA
ATGAGACCTCGTTATTCTGT

Product: heme-hemopexin utilization protein C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 723; Mature: 723

Protein sequence:

>723_residues
MRFSKLSLAITTTLVTANALAQSVELDSINVIATRDPSRFAYTPEKQSKDSLLSKQATSVADALEDIPNVDVRGGSRSIA
QKPNIRGLSDNRVVQVIDGVRQNFDLAHRGSYFLPMSLIQEIEVIKGPSSSLWGSGALGGVVAMRTPNALDLLKNNDKFG
VKIRQGYQTANNLSEKDVSVFAANDKFDVLISGFYNNADNLRTGKGNKLNNTAYKQFGGLAKFGWQINDANRVELSHRET
RFKQTAPSNNEVENELTNEQITDQIKKFHGQKDDLLPPTTQPSPSERSEFYSKVKTRLGSVSYLTDQQIPDQSTVFNYYL
TPDNPYLNTHIALYNNKTIEKEQRKVSGVKDQTKLTTRGINLRNSSELSHISFVYGVDYMRDKIRTERGTNGSDAKFRAD
PYNANSNTTGVYLIAHIPLFGEKLLVSPSVRYDHYDTSSKTVKYKDNHLSPATKLTWIVTNWLDFTAKYNEAFRAPSMQE
RFVSGAHFGANTLGLDHINRFVANPNLRPETAKNKEITANLHFDSLFKQGDKFKIEATYFRNDVKDFINLKIFNDAKTSA
SAGANPNTNGALLPKNSQYQNITNARLSGIELQAQYQTERLTLFTNYGSTKGKDKDSGEALSNIAASKIGVGVNYALVKD
KFTVGATVTHYAAQRRVPKDHSVTYPSYILTDLRATYAPLKGEWKNLRLDFALENLFDRKYQPAFSLMEGTGRNAKISAV
YSF

Sequences:

>Translated_723_residues
MRFSKLSLAITTTLVTANALAQSVELDSINVIATRDPSRFAYTPEKQSKDSLLSKQATSVADALEDIPNVDVRGGSRSIA
QKPNIRGLSDNRVVQVIDGVRQNFDLAHRGSYFLPMSLIQEIEVIKGPSSSLWGSGALGGVVAMRTPNALDLLKNNDKFG
VKIRQGYQTANNLSEKDVSVFAANDKFDVLISGFYNNADNLRTGKGNKLNNTAYKQFGGLAKFGWQINDANRVELSHRET
RFKQTAPSNNEVENELTNEQITDQIKKFHGQKDDLLPPTTQPSPSERSEFYSKVKTRLGSVSYLTDQQIPDQSTVFNYYL
TPDNPYLNTHIALYNNKTIEKEQRKVSGVKDQTKLTTRGINLRNSSELSHISFVYGVDYMRDKIRTERGTNGSDAKFRAD
PYNANSNTTGVYLIAHIPLFGEKLLVSPSVRYDHYDTSSKTVKYKDNHLSPATKLTWIVTNWLDFTAKYNEAFRAPSMQE
RFVSGAHFGANTLGLDHINRFVANPNLRPETAKNKEITANLHFDSLFKQGDKFKIEATYFRNDVKDFINLKIFNDAKTSA
SAGANPNTNGALLPKNSQYQNITNARLSGIELQAQYQTERLTLFTNYGSTKGKDKDSGEALSNIAASKIGVGVNYALVKD
KFTVGATVTHYAAQRRVPKDHSVTYPSYILTDLRATYAPLKGEWKNLRLDFALENLFDRKYQPAFSLMEGTGRNAKISAV
YSF
>Mature_723_residues
MRFSKLSLAITTTLVTANALAQSVELDSINVIATRDPSRFAYTPEKQSKDSLLSKQATSVADALEDIPNVDVRGGSRSIA
QKPNIRGLSDNRVVQVIDGVRQNFDLAHRGSYFLPMSLIQEIEVIKGPSSSLWGSGALGGVVAMRTPNALDLLKNNDKFG
VKIRQGYQTANNLSEKDVSVFAANDKFDVLISGFYNNADNLRTGKGNKLNNTAYKQFGGLAKFGWQINDANRVELSHRET
RFKQTAPSNNEVENELTNEQITDQIKKFHGQKDDLLPPTTQPSPSERSEFYSKVKTRLGSVSYLTDQQIPDQSTVFNYYL
TPDNPYLNTHIALYNNKTIEKEQRKVSGVKDQTKLTTRGINLRNSSELSHISFVYGVDYMRDKIRTERGTNGSDAKFRAD
PYNANSNTTGVYLIAHIPLFGEKLLVSPSVRYDHYDTSSKTVKYKDNHLSPATKLTWIVTNWLDFTAKYNEAFRAPSMQE
RFVSGAHFGANTLGLDHINRFVANPNLRPETAKNKEITANLHFDSLFKQGDKFKIEATYFRNDVKDFINLKIFNDAKTSA
SAGANPNTNGALLPKNSQYQNITNARLSGIELQAQYQTERLTLFTNYGSTKGKDKDSGEALSNIAASKIGVGVNYALVKD
KFTVGATVTHYAAQRRVPKDHSVTYPSYILTDLRATYAPLKGEWKNLRLDFALENLFDRKYQPAFSLMEGTGRNAKISAV
YSF

Specific function: Required for utilization of free heme at low concentrations [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1790405, Length=187, Percent_Identity=31.5508021390374, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1788478, Length=296, Percent_Identity=25.3378378378378, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR011276
- InterPro:   IPR010949
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 80776; Mature: 80776

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFSKLSLAITTTLVTANALAQSVELDSINVIATRDPSRFAYTPEKQSKDSLLSKQATSV
CCCCCEEEEEHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEECCCCCCHHHHHHHHHHHH
ADALEDIPNVDVRGGSRSIAQKPNIRGLSDNRVVQVIDGVRQNFDLAHRGSYFLPMSLIQ
HHHHHHCCCCEECCCCCCHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHCCCEEEHHHHHH
EIEVIKGPSSSLWGSGALGGVVAMRTPNALDLLKNNDKFGVKIRQGYQTANNLSEKDVSV
HHHHHCCCCCCCCCCCCCCCEEEECCCCHHHHHCCCCCEEEEEECCCCHHCCCCCCCEEE
FAANDKFDVLISGFYNNADNLRTGKGNKLNNTAYKQFGGLAKFGWQINDANRVELSHRET
EEECCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHCCHHHCCEEECCCCEEEECHHHH
RFKQTAPSNNEVENELTNEQITDQIKKFHGQKDDLLPPTTQPSPSERSEFYSKVKTRLGS
HHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
VSYLTDQQIPDQSTVFNYYLTPDNPYLNTHIALYNNKTIEKEQRKVSGVKDQTKLTTRGI
EEEECCCCCCCCCEEEEEEECCCCCEEEEEEEEECCCCCHHHHHHHCCCCHHHHHEECCC
NLRNSSELSHISFVYGVDYMRDKIRTERGTNGSDAKFRADPYNANSNTTGVYLIAHIPLF
CCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCEEEEEEECCCC
GEKLLVSPSVRYDHYDTSSKTVKYKDNHLSPATKLTWIVTNWLDFTAKYNEAFRAPSMQE
CCEEEECCCCCCCCCCCCCCEEEECCCCCCCCCEEEEEEEHHHHHHHHHHHHHCCCCHHH
RFVSGAHFGANTLGLDHINRFVANPNLRPETAKNKEITANLHFDSLFKQGDKFKIEATYF
HHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEEEEHHHHHCCCCCEEEEEHHH
RNDVKDFINLKIFNDAKTSASAGANPNTNGALLPKNSQYQNITNARLSGIELQAQYQTER
HHHHHHHHEEEEECCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCEECCEEEEEEECCEE
LTLFTNYGSTKGKDKDSGEALSNIAASKIGVGVNYALVKDKFTVGATVTHYAAQRRVPKD
EEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCEEECCHHHHHHHHHCCCCC
HSVTYPSYILTDLRATYAPLKGEWKNLRLDFALENLFDRKYQPAFSLMEGTGRNAKISAV
CCCCCHHHHHHHHHHHHCCCCCCCHHEEEEHHHHHHHHCCCCCHHHHHHCCCCCEEEEEE
YSF
ECC
>Mature Secondary Structure
MRFSKLSLAITTTLVTANALAQSVELDSINVIATRDPSRFAYTPEKQSKDSLLSKQATSV
CCCCCEEEEEHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEECCCCCCHHHHHHHHHHHH
ADALEDIPNVDVRGGSRSIAQKPNIRGLSDNRVVQVIDGVRQNFDLAHRGSYFLPMSLIQ
HHHHHHCCCCEECCCCCCHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHCCCEEEHHHHHH
EIEVIKGPSSSLWGSGALGGVVAMRTPNALDLLKNNDKFGVKIRQGYQTANNLSEKDVSV
HHHHHCCCCCCCCCCCCCCCEEEECCCCHHHHHCCCCCEEEEEECCCCHHCCCCCCCEEE
FAANDKFDVLISGFYNNADNLRTGKGNKLNNTAYKQFGGLAKFGWQINDANRVELSHRET
EEECCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHCCHHHCCEEECCCCEEEECHHHH
RFKQTAPSNNEVENELTNEQITDQIKKFHGQKDDLLPPTTQPSPSERSEFYSKVKTRLGS
HHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
VSYLTDQQIPDQSTVFNYYLTPDNPYLNTHIALYNNKTIEKEQRKVSGVKDQTKLTTRGI
EEEECCCCCCCCCEEEEEEECCCCCEEEEEEEEECCCCCHHHHHHHCCCCHHHHHEECCC
NLRNSSELSHISFVYGVDYMRDKIRTERGTNGSDAKFRADPYNANSNTTGVYLIAHIPLF
CCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCEEEEEEECCCC
GEKLLVSPSVRYDHYDTSSKTVKYKDNHLSPATKLTWIVTNWLDFTAKYNEAFRAPSMQE
CCEEEECCCCCCCCCCCCCCEEEECCCCCCCCCEEEEEEEHHHHHHHHHHHHHCCCCHHH
RFVSGAHFGANTLGLDHINRFVANPNLRPETAKNKEITANLHFDSLFKQGDKFKIEATYF
HHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEEEEHHHHHCCCCCEEEEEHHH
RNDVKDFINLKIFNDAKTSASAGANPNTNGALLPKNSQYQNITNARLSGIELQAQYQTER
HHHHHHHHEEEEECCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCEECCEEEEEEECCEE
LTLFTNYGSTKGKDKDSGEALSNIAASKIGVGVNYALVKDKFTVGATVTHYAAQRRVPKD
EEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCEEECCHHHHHHHHHCCCCC
HSVTYPSYILTDLRATYAPLKGEWKNLRLDFALENLFDRKYQPAFSLMEGTGRNAKISAV
CCCCCHHHHHHHHHHHHCCCCCCCHHEEEEHHHHHHHHCCCCCHHHHHHCCCCCEEEEEE
YSF
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7751272 [H]