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The map label for this gene is nanK [H]

Identifier: 16272111

GI number: 16272111

Start: 159574

End: 160476

Strand: Reverse

Name: nanK [H]

Synonym: HI0144

Alternate gene names: 16272111

Gene position: 160476-159574 (Counterclockwise)

Preceding gene: 16272112

Following gene: 16272110

Centisome position: 8.77

GC content: 40.42

Gene sequence:

>903_bases
ATGCGTTGTTTAGCACTAGATATTGGTGGGACAAAAATTGCAGCGGCGATTGTAAAAAATGGCGAAATTGAGCAACGTCA
GCAAATTCATACACCACGTGAAAATGTCGTGGAGGGAATGCACCAAGCGTTAGGCAAATTGCTTGCTGATTATGAAGGGC
AGTTTGATTATGTAGCGGTAGCATCTACGGGGATCATCAATAATGGCATTTTAAGTGCATTAAATCCGAAAAACTTAGGT
GGCTTGGCGGAATTTCCACTTAAAGCGAGTATTGCAAAACATACGGATAAACCGATTGGTTTATTAAATGATGCACAAGC
TGCGACTTATGCGGAATATCAATTGCAAAATTCTGAACAGGTATCAAATTTTGTTTTTATTACCGTTTCAACAGGAGTTG
GCGGAGGGATTGTGCTGAACCAAATTTTGCAGACAGGTTCTCGTGGTATTGCTGGGCATATTGGTCATACATTAGCTGAT
CCAAATGGTGCGATCTGTGGTTGTGGGCGTCGAGGTTGTGTCGAAGCGATTGCTTCAGGGCGAGCAATTGAAGCAGTTTC
TTCCCAATGGGAAGAACCGTGCGATCCAAAAGAAGTGTTTGAGCGTTTTAGAAAAAATGATGAAAAAGCGACCGCACTTG
TCGAGCGTTCTGCGAAAGCCATTGCTAATTTAATTGCTGATTTAGTGATTAGTTTAGATATTCAAAAAATCGCGATTGGT
GGCAGTGTGGGATTAGCTGAGGGATATTTATCTTTGGTTGAAAAATATTTACAAGATTTTCCTTCGATATATTGTTGTGA
AATTGAAACCGCTAAATTTGGACAAGATGCAGGTTTAATTGGCGCAGCTTATTGGGTAAAAGATGTTTTACTGGATAAGC
CTGAAGGAACAATTTATGGCTAA

Upstream 100 bases:

>100_bases
TCGTCTTGAACATATTGTGAGTTGGTTTGCTAATTCAGTGAAATCTGCAAGATAGTCGTAAGACGTGTGAGAKAAKGACT
TTACACTATAAGGATAAGTT

Downstream 100 bases:

>100_bases
ATCGGGAAATGTGTTAAACAAAATTGGCTCACTTTACCAGAGTTTAACTAAATCAGAGAAAAAAATTGCCGATACGATTT
TGCGTTCGCCTGATTTAGTC

Product: N-acetylmannosamine kinase

Products: NA

Alternate protein names: ManNAc kinase; N-acetyl-D-mannosamine kinase [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MRCLALDIGGTKIAAAIVKNGEIEQRQQIHTPRENVVEGMHQALGKLLADYEGQFDYVAVASTGIINNGILSALNPKNLG
GLAEFPLKASIAKHTDKPIGLLNDAQAATYAEYQLQNSEQVSNFVFITVSTGVGGGIVLNQILQTGSRGIAGHIGHTLAD
PNGAICGCGRRGCVEAIASGRAIEAVSSQWEEPCDPKEVFERFRKNDEKATALVERSAKAIANLIADLVISLDIQKIAIG
GSVGLAEGYLSLVEKYLQDFPSIYCCEIETAKFGQDAGLIGAAYWVKDVLLDKPEGTIYG

Sequences:

>Translated_300_residues
MRCLALDIGGTKIAAAIVKNGEIEQRQQIHTPRENVVEGMHQALGKLLADYEGQFDYVAVASTGIINNGILSALNPKNLG
GLAEFPLKASIAKHTDKPIGLLNDAQAATYAEYQLQNSEQVSNFVFITVSTGVGGGIVLNQILQTGSRGIAGHIGHTLAD
PNGAICGCGRRGCVEAIASGRAIEAVSSQWEEPCDPKEVFERFRKNDEKATALVERSAKAIANLIADLVISLDIQKIAIG
GSVGLAEGYLSLVEKYLQDFPSIYCCEIETAKFGQDAGLIGAAYWVKDVLLDKPEGTIYG
>Mature_300_residues
MRCLALDIGGTKIAAAIVKNGEIEQRQQIHTPRENVVEGMHQALGKLLADYEGQFDYVAVASTGIINNGILSALNPKNLG
GLAEFPLKASIAKHTDKPIGLLNDAQAATYAEYQLQNSEQVSNFVFITVSTGVGGGIVLNQILQTGSRGIAGHIGHTLAD
PNGAICGCGRRGCVEAIASGRAIEAVSSQWEEPCDPKEVFERFRKNDEKATALVERSAKAIANLIADLVISLDIQKIAIG
GSVGLAEGYLSLVEKYLQDFPSIYCCEIETAKFGQDAGLIGAAYWVKDVLLDKPEGTIYG

Specific function: Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family. NanK subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082230, Length=277, Percent_Identity=49.4584837545126, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1787363, Length=299, Percent_Identity=27.4247491638796, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082127, Length=163, Percent_Identity=31.2883435582822, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787878, Length=252, Percent_Identity=26.1904761904762, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87081733, Length=306, Percent_Identity=24.1830065359477, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786891, Length=174, Percent_Identity=27.5862068965517, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.60 [H]

Molecular weight: Translated: 31919; Mature: 31919

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCLALDIGGTKIAAAIVKNGEIEQRQQIHTPRENVVEGMHQALGKLLADYEGQFDYVAV
CEEEEEECCCHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEE
ASTGIINNGILSALNPKNLGGLAEFPLKASIAKHTDKPIGLLNDAQAATYAEYQLQNSEQ
EECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCC
VSNFVFITVSTGVGGGIVLNQILQTGSRGIAGHIGHTLADPNGAICGCGRRGCVEAIASG
CCCEEEEEEECCCCCHHHHHHHHHCCCCCCHHHHCCCCCCCCCCEECCCCHHHHHHHHCC
RAIEAVSSQWEEPCDPKEVFERFRKNDEKATALVERSAKAIANLIADLVISLDIQKIAIG
CHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEC
GSVGLAEGYLSLVEKYLQDFPSIYCCEIETAKFGQDAGLIGAAYWVKDVLLDKPEGTIYG
CCCHHHHHHHHHHHHHHHHCCCEEEEEECHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRCLALDIGGTKIAAAIVKNGEIEQRQQIHTPRENVVEGMHQALGKLLADYEGQFDYVAV
CEEEEEECCCHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEE
ASTGIINNGILSALNPKNLGGLAEFPLKASIAKHTDKPIGLLNDAQAATYAEYQLQNSEQ
EECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCC
VSNFVFITVSTGVGGGIVLNQILQTGSRGIAGHIGHTLADPNGAICGCGRRGCVEAIASG
CCCEEEEEEECCCCCHHHHHHHHHCCCCCCHHHHCCCCCCCCCCEECCCCHHHHHHHHCC
RAIEAVSSQWEEPCDPKEVFERFRKNDEKATALVERSAKAIANLIADLVISLDIQKIAIG
CHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEC
GSVGLAEGYLSLVEKYLQDFPSIYCCEIETAKFGQDAGLIGAAYWVKDVLLDKPEGTIYG
CCCHHHHHHHHHHHHHHHHCCCEEEEEECHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA