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The map label for this gene is rpiR [C]

Identifier: 16272110

GI number: 16272110

Start: 158715

End: 159581

Strand: Reverse

Name: rpiR [C]

Synonym: HI0143

Alternate gene names: 16272110

Gene position: 159581-158715 (Counterclockwise)

Preceding gene: 16272111

Following gene: 16272109

Centisome position: 8.72

GC content: 37.6

Gene sequence:

>867_bases
ATGGCTAAATCGGGAAATGTGTTAAACAAAATTGGCTCACTTTACCAGAGTTTAACTAAATCAGAGAAAAAAATTGCCGA
TACGATTTTGCGTTCGCCTGATTTAGTCTCTCAATGCTCCCTTTCAGAAATCGCTAAACATTTGCAAGTTGGAGAAGCTA
CGCTCGTCCGTTTTTGTCGAACCATTGGTTTTAAAGGTTTCAGCGAGTTCAAACTAGAGCTTTCTATTGAACTTGCGACG
AAAGATAATCAAGATGAAAGCATACTTGAAACAGAAATTATGCCAAGTGATGATTCGCTCACTATTGCACAAAAATTGCA
AACGGCGGTTGCTAATGTAATGGAAGAAACGATTAATTTACTTGATTTAAAACAGCTTGAAGAAGTCGTTAAAGTACTTA
AAAAAGCACGCCGTATTTTTTTATTTGGGGTGGGTTCATCTGGCGTAACGGCTGAAGATGCTAAAAATAAGCTGATGCGT
ATTGGTTTTCAAGTGGATGCTTCAGGTAATAATCATTTTATGTATATGCAGGCGGCATTATTGACCTCTTCTGATGTGGC
AATTGGTTTAAGCCATTCTGGTTATTCTGCTGAAACGGCGCATACCATCAAAATCGCAAAACAAAATGGTGCAACAACAG
TGGCATTGACGCATAGTTTGCGTTCCCCCGTGACAGAATATGCTGATTATGTTTTGGTAAATGGTAATAAACAAGGCAAG
TTACAAGGCGATTCTATTGGCACCAAAATTGCACAGCTTTTTGTATTAGATTTAATTTATGCTTTGTTAGTGCAGGGCGA
AGAAGATATTGCCGCTCAAACTAAACAAAAAACTCTCAATGTAATTCTTGAACAACGTATAAAATAG

Upstream 100 bases:

>100_bases
TGTGAAATTGAAACCGCTAAATTTGGACAAGATGCAGGTTTAATTGGCGCAGCTTATTGGGTAAAAGATGTTTTACTGGA
TAAGCCTGAAGGAACAATTT

Downstream 100 bases:

>100_bases
GAGAAAACTTATGCGTGATTTAAAAGGTATTTTCAGTGCATTATTAGTGTCATTTAATGAAGATGGCACCATTAATGAAA
AAGGTTTACGCCAAATTATC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MAKSGNVLNKIGSLYQSLTKSEKKIADTILRSPDLVSQCSLSEIAKHLQVGEATLVRFCRTIGFKGFSEFKLELSIELAT
KDNQDESILETEIMPSDDSLTIAQKLQTAVANVMEETINLLDLKQLEEVVKVLKKARRIFLFGVGSSGVTAEDAKNKLMR
IGFQVDASGNNHFMYMQAALLTSSDVAIGLSHSGYSAETAHTIKIAKQNGATTVALTHSLRSPVTEYADYVLVNGNKQGK
LQGDSIGTKIAQLFVLDLIYALLVQGEEDIAAQTKQKTLNVILEQRIK

Sequences:

>Translated_288_residues
MAKSGNVLNKIGSLYQSLTKSEKKIADTILRSPDLVSQCSLSEIAKHLQVGEATLVRFCRTIGFKGFSEFKLELSIELAT
KDNQDESILETEIMPSDDSLTIAQKLQTAVANVMEETINLLDLKQLEEVVKVLKKARRIFLFGVGSSGVTAEDAKNKLMR
IGFQVDASGNNHFMYMQAALLTSSDVAIGLSHSGYSAETAHTIKIAKQNGATTVALTHSLRSPVTEYADYVLVNGNKQGK
LQGDSIGTKIAQLFVLDLIYALLVQGEEDIAAQTKQKTLNVILEQRIK
>Mature_287_residues
AKSGNVLNKIGSLYQSLTKSEKKIADTILRSPDLVSQCSLSEIAKHLQVGEATLVRFCRTIGFKGFSEFKLELSIELATK
DNQDESILETEIMPSDDSLTIAQKLQTAVANVMEETINLLDLKQLEEVVKVLKKARRIFLFGVGSSGVTAEDAKNKLMRI
GFQVDASGNNHFMYMQAALLTSSDVAIGLSHSGYSAETAHTIKIAKQNGATTVALTHSLRSPVTEYADYVLVNGNKQGKL
QGDSIGTKIAQLFVLDLIYALLVQGEEDIAAQTKQKTLNVILEQRIK

Specific function: Regulatory Protein Involved In Rpib Gene Repression. Also Involved In Als Operon Repression. [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

Organism=Escherichia coli, GI87082369, Length=263, Percent_Identity=26.615969581749, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1788767, Length=261, Percent_Identity=31.0344827586207, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI87082130, Length=268, Percent_Identity=28.3582089552239, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1788159, Length=261, Percent_Identity=30.2681992337165, Blast_Score=110, Evalue=9e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y143_HAEIN (P44540)

Other databases:

- EMBL:   L42023
- RefSeq:   NP_438312.1
- ProteinModelPortal:   P44540
- GeneID:   951052
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0143
- NMPDR:   fig|71421.1.peg.134
- TIGR:   HI_0143
- HOGENOM:   HBG725281
- OMA:   HEVDTTA
- ProtClustDB:   CLSK870584
- BioCyc:   HINF71421:HI_0143-MONOMER
- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10

Pfam domain/function: PF01418 HTH_6; PF01380 SIS

EC number: NA

Molecular weight: Translated: 31466; Mature: 31334

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS51071 HTH_RPIR; PS51464 SIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSGNVLNKIGSLYQSLTKSEKKIADTILRSPDLVSQCSLSEIAKHLQVGEATLVRFCR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHCCHHHHHHHHH
TIGFKGFSEFKLELSIELATKDNQDESILETEIMPSDDSLTIAQKLQTAVANVMEETINL
HHCCCCCCEEEEEEEEEEECCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LDLKQLEEVVKVLKKARRIFLFGVGSSGVTAEDAKNKLMRIGFQVDASGNNHFMYMQAAL
HHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHEEEEEECCCCCEEEEEEEEH
LTSSDVAIGLSHSGYSAETAHTIKIAKQNGATTVALTHSLRSPVTEYADYVLVNGNKQGK
HCCCCEEEEECCCCCCCCCEEEEEEEECCCCEEEEEHHHHHCCHHHHCCEEEEECCCCCC
LQGDSIGTKIAQLFVLDLIYALLVQGEEDIAAQTKQKTLNVILEQRIK
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKSGNVLNKIGSLYQSLTKSEKKIADTILRSPDLVSQCSLSEIAKHLQVGEATLVRFCR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHCCHHHHHHHHH
TIGFKGFSEFKLELSIELATKDNQDESILETEIMPSDDSLTIAQKLQTAVANVMEETINL
HHCCCCCCEEEEEEEEEEECCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LDLKQLEEVVKVLKKARRIFLFGVGSSGVTAEDAKNKLMRIGFQVDASGNNHFMYMQAAL
HHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHEEEEEECCCCCEEEEEEEEH
LTSSDVAIGLSHSGYSAETAHTIKIAKQNGATTVALTHSLRSPVTEYADYVLVNGNKQGK
HCCCCEEEEECCCCCCCCCEEEEEEEECCCCEEEEEHHHHHCCHHHHCCEEEEECCCCCC
LQGDSIGTKIAQLFVLDLIYALLVQGEEDIAAQTKQKTLNVILEQRIK
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800