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The map label for this gene is engA [H]

Identifier: 16272103

GI number: 16272103

Start: 150287

End: 151801

Strand: Reverse

Name: engA [H]

Synonym: HI0136

Alternate gene names: 16272103

Gene position: 151801-150287 (Counterclockwise)

Preceding gene: 16272104

Following gene: 16272098

Centisome position: 8.29

GC content: 40.0

Gene sequence:

>1515_bases
ATGGCAACTCCAGTCGTCGCCCTTGTTGGTCGCCCAAATGTGGGAAAATCCACATTATTTAATCGCCTTACTCGTACGAG
AGATGCGTTAGTCGCTGATTTTCCCGGTTTAACTCGTGATAGAAAATATGGTCACGCACATATTGCTGGCTATGATTTTA
TTGTTATTGATACTGGCGGTATTGATGGAACGGAAGAGGGTGTAGAAGAAAAAATGGCGGAGCAATCTTTGCTTGCTATT
GATGAAGCGGATATTGTTCTTTTCCTTGTGGATGCTAGAGCGGGTTTAACGGCAGCTGATATTGGTATTGCTAATTATTT
ACGCCAACGTCAAAACAAAATTACTGTGGTGGTGGCAAATAAAACTGATGGTATTGATGCGGATTCCCATTGTGCTGAAT
TTTATCAGTTAGGTTTAGGGGAAATTGAGCAAATCGCAGCCTCACAAGGCCGTGGTGTTACTCAATTAATGGAACAAGTA
CTTGCGCCTTTTGCGGAAAAAATGGAAAACGCCGATGAAAATGACCGCACTTCTGAGGAAGAACAAGACGAATGGGAACA
AGAATTCGATTTTGATTCAGAAGAAGATACGGCATTAATTGATGATGCGTTAGACGAAGAACTTGAAGAAGAACAAGATA
AAAATATTAAGATTGCCATTGTTGGTCGTCCAAATGTGGGTAAATCTACTTTAACCAATCGTATTTTAGGCGAAGATCGT
GTCGTGGTTTTTGATATGCCAGGTACGACACGTGACAGTATTTATATTCCAATGGAGCGTGATGGGCAGCAATATACCTT
GATTGATACGGCTGGTGTGCGTAAGCGTGGTAAAGTGCATTTGGCAGTGGAAAAATTCTCTGTGATTAAAACCTTACAAG
CGATTCAAGATGCTAATGTTGTATTGCTGACTATTGATGCGAGAGAGAACATTTCTGATCAGGATTTATCTTTGCTCGGC
TTTATTTTAAATGCAGGGCGTTCTTTGGTGATCGTCGTGAATAAATGGGATGGTTTAGATCAAGATGTGAAAGATCGTGT
GAAATCTGAACTTGATCGTCGTTTAGATTTTATTGATTTTGCTCGGGTGCATTTTATTTCAGCCTTGCACGGAAGTGGTG
TAGGTAATCTTTTTGATTCGATTAAAGAAGCCTATGCTTGTGCCACTCAAAAAATGACGACTTCGCTTTTAACTCGTATT
TTGCAAATGGCAACGGATGAGCACCAACCGCCGATGATTGGCGGTCGTCGCATTAAATTAAAATATGCTCACCCAGGTGG
TTATAATCCGCCGATTATAGTGGTTCACGGTAACCAAATGGATAAACTACCAGATTCTTATAAACGTTATTTATCTAATT
ATTATCGTAAGAGCTTAAAAATTATTGGTTCACCGATTCGTCTGCTTTTCCAAGAAGGCTCAAACCCATTTGCAGGACGC
AAAAATAAACTCACTCCGAACCAATTGCGTAAACGTAAACGTTTGATGAAATTTATTAAGAAAGCGAAACGTTAA

Upstream 100 bases:

>100_bases
GTATCCTGTGGCTTTTTCTTTTCTTTATGAAATGATTTTTTACCAATCCTTTAACTTCCGATATAATAGTCGCCATTTTT
GACAAAATAAGAGATTTTTT

Downstream 100 bases:

>100_bases
ACGCAAGATAAATAAAACTTAGCAAGATTTAACCGCACTTTTAAAACTCTTTTTGGAGAACTAAAGTGCGGTTATTTTTT
TATTTGTTTTGCAGAAGAAA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 504; Mature: 503

Protein sequence:

>504_residues
MATPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGHAHIAGYDFIVIDTGGIDGTEEGVEEKMAEQSLLAI
DEADIVLFLVDARAGLTAADIGIANYLRQRQNKITVVVANKTDGIDADSHCAEFYQLGLGEIEQIAASQGRGVTQLMEQV
LAPFAEKMENADENDRTSEEEQDEWEQEFDFDSEEDTALIDDALDEELEEEQDKNIKIAIVGRPNVGKSTLTNRILGEDR
VVVFDMPGTTRDSIYIPMERDGQQYTLIDTAGVRKRGKVHLAVEKFSVIKTLQAIQDANVVLLTIDARENISDQDLSLLG
FILNAGRSLVIVVNKWDGLDQDVKDRVKSELDRRLDFIDFARVHFISALHGSGVGNLFDSIKEAYACATQKMTTSLLTRI
LQMATDEHQPPMIGGRRIKLKYAHPGGYNPPIIVVHGNQMDKLPDSYKRYLSNYYRKSLKIIGSPIRLLFQEGSNPFAGR
KNKLTPNQLRKRKRLMKFIKKAKR

Sequences:

>Translated_504_residues
MATPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGHAHIAGYDFIVIDTGGIDGTEEGVEEKMAEQSLLAI
DEADIVLFLVDARAGLTAADIGIANYLRQRQNKITVVVANKTDGIDADSHCAEFYQLGLGEIEQIAASQGRGVTQLMEQV
LAPFAEKMENADENDRTSEEEQDEWEQEFDFDSEEDTALIDDALDEELEEEQDKNIKIAIVGRPNVGKSTLTNRILGEDR
VVVFDMPGTTRDSIYIPMERDGQQYTLIDTAGVRKRGKVHLAVEKFSVIKTLQAIQDANVVLLTIDARENISDQDLSLLG
FILNAGRSLVIVVNKWDGLDQDVKDRVKSELDRRLDFIDFARVHFISALHGSGVGNLFDSIKEAYACATQKMTTSLLTRI
LQMATDEHQPPMIGGRRIKLKYAHPGGYNPPIIVVHGNQMDKLPDSYKRYLSNYYRKSLKIIGSPIRLLFQEGSNPFAGR
KNKLTPNQLRKRKRLMKFIKKAKR
>Mature_503_residues
ATPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGHAHIAGYDFIVIDTGGIDGTEEGVEEKMAEQSLLAID
EADIVLFLVDARAGLTAADIGIANYLRQRQNKITVVVANKTDGIDADSHCAEFYQLGLGEIEQIAASQGRGVTQLMEQVL
APFAEKMENADENDRTSEEEQDEWEQEFDFDSEEDTALIDDALDEELEEEQDKNIKIAIVGRPNVGKSTLTNRILGEDRV
VVFDMPGTTRDSIYIPMERDGQQYTLIDTAGVRKRGKVHLAVEKFSVIKTLQAIQDANVVLLTIDARENISDQDLSLLGF
ILNAGRSLVIVVNKWDGLDQDVKDRVKSELDRRLDFIDFARVHFISALHGSGVGNLFDSIKEAYACATQKMTTSLLTRIL
QMATDEHQPPMIGGRRIKLKYAHPGGYNPPIIVVHGNQMDKLPDSYKRYLSNYYRKSLKIIGSPIRLLFQEGSNPFAGRK
NKLTPNQLRKRKRLMKFIKKAKR

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=501, Percent_Identity=70.2594810379242, Blast_Score=708, Evalue=0.0,
Organism=Escherichia coli, GI2367268, Length=93, Percent_Identity=37.6344086021505, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17507259, Length=131, Percent_Identity=31.2977099236641, Blast_Score=66, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=143, Percent_Identity=30.7692307692308, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 56438; Mature: 56307

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGHAHIAGYDFIVIDTGG
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECEEEEEEECCC
IDGTEEGVEEKMAEQSLLAIDEADIVLFLVDARAGLTAADIGIANYLRQRQNKITVVVAN
CCCCHHHHHHHHHHHHHHEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEEEC
KTDGIDADSHCAEFYQLGLGEIEQIAASQGRGVTQLMEQVLAPFAEKMENADENDRTSEE
CCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCH
EQDEWEQEFDFDSEEDTALIDDALDEELEEEQDKNIKIAIVGRPNVGKSTLTNRILGEDR
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHCCCCC
VVVFDMPGTTRDSIYIPMERDGQQYTLIDTAGVRKRGKVHLAVEKFSVIKTLQAIQDANV
EEEEECCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHCCCCE
VLLTIDARENISDQDLSLLGFILNAGRSLVIVVNKWDGLDQDVKDRVKSELDRRLDFIDF
EEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
ARVHFISALHGSGVGNLFDSIKEAYACATQKMTTSLLTRILQMATDEHQPPMIGGRRIKL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
KYAHPGGYNPPIIVVHGNQMDKLPDSYKRYLSNYYRKSLKIIGSPIRLLFQEGSNPFAGR
EEECCCCCCCCEEEEECCCHHCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCC
KNKLTPNQLRKRKRLMKFIKKAKR
CCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGHAHIAGYDFIVIDTGG
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECEEEEEEECCC
IDGTEEGVEEKMAEQSLLAIDEADIVLFLVDARAGLTAADIGIANYLRQRQNKITVVVAN
CCCCHHHHHHHHHHHHHHEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEEEC
KTDGIDADSHCAEFYQLGLGEIEQIAASQGRGVTQLMEQVLAPFAEKMENADENDRTSEE
CCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCH
EQDEWEQEFDFDSEEDTALIDDALDEELEEEQDKNIKIAIVGRPNVGKSTLTNRILGEDR
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHCCCCC
VVVFDMPGTTRDSIYIPMERDGQQYTLIDTAGVRKRGKVHLAVEKFSVIKTLQAIQDANV
EEEEECCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHCCCCE
VLLTIDARENISDQDLSLLGFILNAGRSLVIVVNKWDGLDQDVKDRVKSELDRRLDFIDF
EEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
ARVHFISALHGSGVGNLFDSIKEAYACATQKMTTSLLTRILQMATDEHQPPMIGGRRIKL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
KYAHPGGYNPPIIVVHGNQMDKLPDSYKRYLSNYYRKSLKIIGSPIRLLFQEGSNPFAGR
EEECCCCCCCCEEEEECCCHHCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCC
KNKLTPNQLRKRKRLMKFIKKAKR
CCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]