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The map label for this gene is udk

Identifier: 16272099

GI number: 16272099

Start: 146601

End: 147242

Strand: Direct

Name: udk

Synonym: HI0132

Alternate gene names: 16272099

Gene position: 146601-147242 (Clockwise)

Preceding gene: 16272095

Following gene: 16272100

Centisome position: 8.01

GC content: 38.16

Gene sequence:

>642_bases
ATGTCAAATCCCTCTTGTATCATCATCGCCATCACAGGTGCATCTGCATCAGGCAAAAGTTCTATCGCTTCCACTGTTCA
CAAAGAGCTCTGTAATGAACTAGGCTGCCAAGAAATTGGTATCATTACTGAAGACAGTTACTATAAAGATCAAAGTCATT
TAGAAATGACTGAGCGGGTAAAAACGAATTACGATCATCCAAACTCTATGGATCGCGATTTACTTATCCAACATTTAAAA
AATCTAAAAAATGGCAGTGCAGTAGATGTGCCTGTTTATAGCTATGTAGAACATACTCGCACCAACGAAACAACGCATTT
CACACCAAAACGAATCGTAATTTTAGAAGGGATTTTATTACTTACCGATGAACGAGTACGCCAATTAGCCGATATTTCTG
TATTCGTAGACACACCACTTGATATTTGTTTCATCCGCCGTTTACAACGTGATATGGAAGAACGTGGTCGCTCTCTACAA
TCAGTGATTGATCAATATCGTGCAACCGTGCGTCCAATGTTCTTACAATTTATTGAGCCGTCTAAACAATATGCGGATAT
TGTCATTCCTCGTGGTGGTAAAAATCGCATTGCGATCAATATGTTAAAAGCTCAAATCCTTCATTTATTGAATCAAAAAT
AG

Upstream 100 bases:

>100_bases
GAAGTTCACAGTTTTTAAAATTCAAGTGAAAAAATANACGTGAAATTCACCGCACTTTTCTTTATAATTGCAAGAATTTT
CCTTACATCGAAACACGATT

Downstream 100 bases:

>100_bases
GAAATCTTATGCGTCTTTGCGATACTGATATTGAACGCTATCTTGATGATGGCATTATTTCTTTAACACCACGTCCAAAT
AATGACAAAATCAACGGTGC

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MSNPSCIIIAITGASASGKSSIASTVHKELCNELGCQEIGIITEDSYYKDQSHLEMTERVKTNYDHPNSMDRDLLIQHLK
NLKNGSAVDVPVYSYVEHTRTNETTHFTPKRIVILEGILLLTDERVRQLADISVFVDTPLDICFIRRLQRDMEERGRSLQ
SVIDQYRATVRPMFLQFIEPSKQYADIVIPRGGKNRIAINMLKAQILHLLNQK

Sequences:

>Translated_213_residues
MSNPSCIIIAITGASASGKSSIASTVHKELCNELGCQEIGIITEDSYYKDQSHLEMTERVKTNYDHPNSMDRDLLIQHLK
NLKNGSAVDVPVYSYVEHTRTNETTHFTPKRIVILEGILLLTDERVRQLADISVFVDTPLDICFIRRLQRDMEERGRSLQ
SVIDQYRATVRPMFLQFIEPSKQYADIVIPRGGKNRIAINMLKAQILHLLNQK
>Mature_212_residues
SNPSCIIIAITGASASGKSSIASTVHKELCNELGCQEIGIITEDSYYKDQSHLEMTERVKTNYDHPNSMDRDLLIQHLKN
LKNGSAVDVPVYSYVEHTRTNETTHFTPKRIVILEGILLLTDERVRQLADISVFVDTPLDICFIRRLQRDMEERGRSLQS
VIDQYRATVRPMFLQFIEPSKQYADIVIPRGGKNRIAINMLKAQILHLLNQK

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family

Homologues:

Organism=Homo sapiens, GI18699734, Length=210, Percent_Identity=37.6190476190476, Blast_Score=161, Evalue=5e-40,
Organism=Homo sapiens, GI301129207, Length=207, Percent_Identity=36.7149758454106, Blast_Score=155, Evalue=2e-38,
Organism=Homo sapiens, GI57863312, Length=210, Percent_Identity=36.1904761904762, Blast_Score=155, Evalue=2e-38,
Organism=Homo sapiens, GI13899253, Length=210, Percent_Identity=36.6666666666667, Blast_Score=150, Evalue=6e-37,
Organism=Homo sapiens, GI209863022, Length=146, Percent_Identity=33.5616438356164, Blast_Score=94, Evalue=9e-20,
Organism=Escherichia coli, GI87082034, Length=201, Percent_Identity=68.1592039800995, Blast_Score=299, Evalue=8e-83,
Organism=Caenorhabditis elegans, GI17539894, Length=209, Percent_Identity=36.3636363636364, Blast_Score=157, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17539892, Length=209, Percent_Identity=36.3636363636364, Blast_Score=157, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI71981181, Length=202, Percent_Identity=33.6633663366337, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6324339, Length=182, Percent_Identity=31.8681318681319, Blast_Score=115, Evalue=4e-27,
Organism=Drosophila melanogaster, GI28573516, Length=198, Percent_Identity=37.3737373737374, Blast_Score=150, Evalue=7e-37,
Organism=Drosophila melanogaster, GI28573514, Length=198, Percent_Identity=37.3737373737374, Blast_Score=150, Evalue=7e-37,
Organism=Drosophila melanogaster, GI28573512, Length=198, Percent_Identity=37.3737373737374, Blast_Score=150, Evalue=7e-37,
Organism=Drosophila melanogaster, GI45550449, Length=198, Percent_Identity=37.3737373737374, Blast_Score=150, Evalue=8e-37,
Organism=Drosophila melanogaster, GI221458995, Length=223, Percent_Identity=34.9775784753363, Blast_Score=141, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24649624, Length=220, Percent_Identity=35, Blast_Score=139, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URK_HAEI8 (Q4QP55)

Other databases:

- EMBL:   CP000057
- RefSeq:   YP_247852.1
- ProteinModelPortal:   Q4QP55
- SMR:   Q4QP55
- STRING:   Q4QP55
- GeneID:   3429556
- GenomeReviews:   CP000057_GR
- KEGG:   hit:NTHI0218
- eggNOG:   COG0572
- HOGENOM:   HBG527126
- OMA:   DQIGVIA
- PhylomeDB:   Q4QP55
- ProtClustDB:   PRK05480
- BioCyc:   HINF281310:NTHI0218-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00551
- InterPro:   IPR006083
- InterPro:   IPR000764
- PANTHER:   PTHR10285:SF6
- PRINTS:   PR00988
- TIGRFAMs:   TIGR00235

Pfam domain/function: PF00485 PRK

EC number: =2.7.1.48

Molecular weight: Translated: 24284; Mature: 24153

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNPSCIIIAITGASASGKSSIASTVHKELCNELGCQEIGIITEDSYYKDQSHLEMTERV
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHH
KTNYDHPNSMDRDLLIQHLKNLKNGSAVDVPVYSYVEHTRTNETTHFTPKRIVILEGILL
HCCCCCCCCCCHHHHHHHHHHCCCCCEECCHHHHHHHHHCCCCCCCCCCCEEHHHHHHHH
LTDERVRQLADISVFVDTPLDICFIRRLQRDMEERGRSLQSVIDQYRATVRPMFLQFIEP
CCHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SKQYADIVIPRGGKNRIAINMLKAQILHLLNQK
CCHHCCEEEECCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SNPSCIIIAITGASASGKSSIASTVHKELCNELGCQEIGIITEDSYYKDQSHLEMTERV
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHH
KTNYDHPNSMDRDLLIQHLKNLKNGSAVDVPVYSYVEHTRTNETTHFTPKRIVILEGILL
HCCCCCCCCCCHHHHHHHHHHCCCCCEECCHHHHHHHHHCCCCCCCCCCCEEHHHHHHHH
LTDERVRQLADISVFVDTPLDICFIRRLQRDMEERGRSLQSVIDQYRATVRPMFLQFIEP
CCHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SKQYADIVIPRGGKNRIAINMLKAQILHLLNQK
CCHHCCEEEECCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA