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The map label for this gene is znuA

Identifier: 16272089

GI number: 16272089

Start: 133907

End: 134920

Strand: Direct

Name: znuA

Synonym: HI0119

Alternate gene names: 16272089

Gene position: 133907-134920 (Clockwise)

Preceding gene: 16272088

Following gene: 16272093

Centisome position: 7.32

GC content: 36.79

Gene sequence:

>1014_bases
ATGAAAAAACTTTTAAAAATTAGTGCCATTTCTGCCGCACTTTTAAGTGCGCCAATGATGGCGAATGCCGATGTATTAGC
ATCAGTAAAACCTTTAGGCTTTATTGTTTCATCTATTGCAGATGGCGTAACTGGTACACAAGTCCTTGTTCCTGCTGGCG
CCTCTCCGCATGATTACAATTTGAAATTATCTGATATTCAAAAAGTAAAATCTGCAGATTTAGTTGTATGGATTGGTGAA
GACATTGATTCATTCTTAGACAAACCAATTAGCCAAATTGAACGTAAAAAAGTGATTACCATTGCCGATCTTGCGGATGT
AAAACCTTTATTAAGTAAAGCTCACCATGAGCATTTCCATGAAGATGGCGATCATGATCATGACCATAAGCACGAACACA
AACATGATCATAAACACGACCATGACCATGATCATGATCATAAACACGAGCATAAACACGACCACGAACATCATGATCAC
GATCATCACGAGGGTTTAACAACAAACTGGCACGTTTGGTATTCTCCAGCTATCAGCAAAATTGTTGCACAAAAAGTAGC
GGATAAATTAACTGCACAATTCCCAGATAAAAAAGCGTTAATTGCACAAAATCTTTCAGATTTTAACCGCACTTTGGCAG
AACAAAGTGAAAAAATTACGGCACAACTTGCAAATGTTAAAGATAAAGGTTTCTACGTTTTCCACGATGCTTATGGTTAT
TTCAACGATGCTTATGGTTTAAAACAAACGGGTTACTTTACCATCAATCCATTAGTGGCACCGGGTGCAAAAACTTTAGC
GCACATTAAAGAAGAAATTGATGAACATAAAGTAAATTGCTTATTCGCAGAGCCTCAATTTACGCCAAAAGTGATTGAGT
CTTTAGCGAAAAATACTAAAGTCAATGTAGGACAACTCGACCCAATTGGCGATAAAGTTACTTTAGGTAAAAATTCTTAT
GCAACATTCTTGCAATCTACTGCAGATAGCTACATGGAATGTTTAGCTAAATAA

Upstream 100 bases:

>100_bases
ATTTTCCCTCTTTTTACTATAAAATCGTTGCAATTTATATAAAAAGGCGTACTCTTTTTTCCCTTTGAGAATTACTACCA
ACAAGTAAGGAAACATAAAT

Downstream 100 bases:

>100_bases
ACCTTTCTAAAAACAATGACCGCACATAAAAGTGCGGTCATTTTTTTTTCTAAATTTGATATTTAGTTTTATCTCCAATA
TCAAAATGCAAAGGCATTCG

Product: high-affinity zinc transporter periplasmic component

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MKKLLKISAISAALLSAPMMANADVLASVKPLGFIVSSIADGVTGTQVLVPAGASPHDYNLKLSDIQKVKSADLVVWIGE
DIDSFLDKPISQIERKKVITIADLADVKPLLSKAHHEHFHEDGDHDHDHKHEHKHDHKHDHDHDHDHKHEHKHDHEHHDH
DHHEGLTTNWHVWYSPAISKIVAQKVADKLTAQFPDKKALIAQNLSDFNRTLAEQSEKITAQLANVKDKGFYVFHDAYGY
FNDAYGLKQTGYFTINPLVAPGAKTLAHIKEEIDEHKVNCLFAEPQFTPKVIESLAKNTKVNVGQLDPIGDKVTLGKNSY
ATFLQSTADSYMECLAK

Sequences:

>Translated_337_residues
MKKLLKISAISAALLSAPMMANADVLASVKPLGFIVSSIADGVTGTQVLVPAGASPHDYNLKLSDIQKVKSADLVVWIGE
DIDSFLDKPISQIERKKVITIADLADVKPLLSKAHHEHFHEDGDHDHDHKHEHKHDHKHDHDHDHDHKHEHKHDHEHHDH
DHHEGLTTNWHVWYSPAISKIVAQKVADKLTAQFPDKKALIAQNLSDFNRTLAEQSEKITAQLANVKDKGFYVFHDAYGY
FNDAYGLKQTGYFTINPLVAPGAKTLAHIKEEIDEHKVNCLFAEPQFTPKVIESLAKNTKVNVGQLDPIGDKVTLGKNSY
ATFLQSTADSYMECLAK
>Mature_337_residues
MKKLLKISAISAALLSAPMMANADVLASVKPLGFIVSSIADGVTGTQVLVPAGASPHDYNLKLSDIQKVKSADLVVWIGE
DIDSFLDKPISQIERKKVITIADLADVKPLLSKAHHEHFHEDGDHDHDHKHEHKHDHKHDHDHDHDHKHEHKHDHEHHDH
DHHEGLTTNWHVWYSPAISKIVAQKVADKLTAQFPDKKALIAQNLSDFNRTLAEQSEKITAQLANVKDKGFYVFHDAYGY
FNDAYGLKQTGYFTINPLVAPGAKTLAHIKEEIDEHKVNCLFAEPQFTPKVIESLAKNTKVNVGQLDPIGDKVTLGKNSY
ATFLQSTADSYMECLAK

Specific function: Involved in the high-affinity zinc uptake transport system

COG id: COG4531

COG function: function code P; ABC-type Zn2+ transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Periplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family

Homologues:

Organism=Escherichia coli, GI87081990, Length=320, Percent_Identity=42.5, Blast_Score=273, Evalue=1e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ZNUA_HAEIN (P44526)

Other databases:

- EMBL:   L42023
- PIR:   D64049
- RefSeq:   NP_438291.1
- ProteinModelPortal:   P44526
- SMR:   P44526
- GeneID:   951027
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0119
- NMPDR:   fig|71421.1.peg.113
- TIGR:   HI_0119
- HOGENOM:   HBG731008
- OMA:   KHEHKHD
- ProtClustDB:   PRK09545
- BioCyc:   HINF71421:HI_0119-MONOMER
- InterPro:   IPR006127

Pfam domain/function: PF01297 SBP_bac_9

EC number: NA

Molecular weight: Translated: 37660; Mature: 37660

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLKISAISAALLSAPMMANADVLASVKPLGFIVSSIADGVTGTQVLVPAGASPHDYN
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCC
LKLSDIQKVKSADLVVWIGEDIDSFLDKPISQIERKKVITIADLADVKPLLSKAHHEHFH
CCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCEEEEHHHHHHHHHHHHHHHHHHC
EDGDHDHDHKHEHKHDHKHDHDHDHDHKHEHKHDHEHHDHDHHEGLTTNWHVWYSPAISK
CCCCCCCCCCHHHCCCCCCCCCCCCCCCHHHCCCCCCCCCCHHCCCCCCEEEEECHHHHH
IVAQKVADKLTAQFPDKKALIAQNLSDFNRTLAEQSEKITAQLANVKDKGFYVFHDAYGY
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
FNDAYGLKQTGYFTINPLVAPGAKTLAHIKEEIDEHKVNCLFAEPQFTPKVIESLAKNTK
HHCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCC
VNVGQLDPIGDKVTLGKNSYATFLQSTADSYMECLAK
CCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKLLKISAISAALLSAPMMANADVLASVKPLGFIVSSIADGVTGTQVLVPAGASPHDYN
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCC
LKLSDIQKVKSADLVVWIGEDIDSFLDKPISQIERKKVITIADLADVKPLLSKAHHEHFH
CCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCEEEEHHHHHHHHHHHHHHHHHHC
EDGDHDHDHKHEHKHDHKHDHDHDHDHKHEHKHDHEHHDHDHHEGLTTNWHVWYSPAISK
CCCCCCCCCCHHHCCCCCCCCCCCCCCCHHHCCCCCCCCCCHHCCCCCCEEEEECHHHHH
IVAQKVADKLTAQFPDKKALIAQNLSDFNRTLAEQSEKITAQLANVKDKGFYVFHDAYGY
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
FNDAYGLKQTGYFTINPLVAPGAKTLAHIKEEIDEHKVNCLFAEPQFTPKVIESLAKNTK
HHCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCC
VNVGQLDPIGDKVTLGKNSYATFLQSTADSYMECLAK
CCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023