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The map label for this gene is nrdD

Identifier: 16272049

GI number: 16272049

Start: 80526

End: 82649

Strand: Direct

Name: nrdD

Synonym: HI0075

Alternate gene names: 16272049

Gene position: 80526-82649 (Clockwise)

Preceding gene: 30995352

Following gene: 16272050

Centisome position: 4.4

GC content: 41.71

Gene sequence:

>2124_bases
ATGAGTAACTTTGGGGTCATCAAGCGCGATGGTTCTCGTGCGGAGTTTGAGATTCAACGTATCATTAATGCCATTAAAAA
AGCCGCAAGTGCGGTCAATATTTCCGATGAATTTTATTGCCACCAAATTGGGCAAGAAGTAGGGAATGAAATTTTCACCC
GTCATCAAGGCGAGATTGATATTAATCAGATTCAAAAAATCGTTGAAGATAAATTGATGGCAAGTCGTTATCCTGAGGTT
GCTCGTGCGTATATCGAATATCGTCATGATCGTGATTTAGCACGAGAAAAACGTAGCCAGCTAACAAAAGAAATTGAAGG
TTTGATTGAACAAAGCAACGTAGAATTACTTAATGAAAACGCCAATAAAGACGCGAAAGTGATTCCAACGCAACGAGATT
TGCTTGCTGGAATTGTGGCAAAACATTATGCCAAGCACAATATTCTTCCACGCGATGTGGTAGAGGCTCACGAAAAAGGT
GAAATTCATTATCACGATTTAGATTACGCGCCGTTCTTTCCAATGTTTAACTGTATGTTAGTTGATTTAGAAGGGATGCT
TTCTCGTGGTTTCAAAATGGGCAATGCGGAAATCGAACCCCCTAAATCTATCGGCACCGCAACGGCAGTGACAGCACAAA
TTATCGCCCAAGTTGCCAGCCATATTTACGGTGGCACAACCATTAATCGTATTGATGAAGTGCTTTCCCCTTATGTGCAA
ATCAGTTACGAAAAACACCTCAAACATGCCCAAGAATGGAACGTGCCTGATGTTGAAGGTTATGCCAAAGCATTGATTGA
AAAAGAATGTTTCGATGCCTTCCAATCCTTAGAATATGAAGTTAATACACTACATACTTCAAATGGGCAAACACCATTTG
TGACCTTTGGTTTTGGTTTAGGTACAAGCTGGCAATCCCGCTTAATTCAGCAAGCTATTTTAAAAAATCGGATTCGTGGA
CTTGGAAAAAATCATAAAACACCAGTATTTCCAAAACTTGTTTTCACCATCAAAAAAGGTTTGAACCAAAATAAAGGCGA
TCCGAATTACGATATCAAACAACTCGCATTAGAATGCGCATCAAAACGTATGTATCCAGATATTCTCAATTACGATCAGG
TTGTCAAAGTCACGGGCTCTTTTAAAGCCCCAATGGGATGCCGTAGCTTTTTAGGTGCATACGAAGAAAAAGGCCACGAA
ATTCACGATGGGCGTAATAATCTTGGCGTGGTGAGTTTGAATTTACCGCGTATTGCGTTGGAGTCCAAAAACGAAGAAGA
TTTCTACCGCACTTTAGATGAACGTTTGGCTATTGCGAAAAAAGCATTAATGACGCGCATTGCCCGCCTTGAGAATACCA
AAGCTCGCGTCGCTCCTATTCTTTATATGGAAGGTGCTTGCGGAGTGCGGTTAAAAGCGGATGAAAATGTGGCACAAATT
TTCAAAAATGGACGTGCCTCTATTTCACTTGGCTATATCGGTATTCACGAAACCATTAATGCACTATATAACAAAGGACA
TATTTTTGATGATGAACAATTACGCGAAAAAGGCATTGCGATTGTTCGCCACCTTAGCGAGGCAGTGAAACGCTGGCAAA
AAGAAACAGGTTATGCCTTCAGCCTTTACTCCACGCCAAGCGAAAACTTATGCGACCGCTTCTGCCGTCTAGATACCAAA
AAATTTGGCGTAATTGAAGGCGTCACGGATAAAGGCTACTACACGAACAGTTACCACTTAGATGTAGAAAAGAAAGTGAA
TCCTTACGATAAACTAGATTTCGAAATGACATATCCCCCACTCGCCAGCGGCGGTTTTATTTGCTACGGCGAATATCCCA
ATATTCAACACAACTTAAAAGCATTGGAAGATGTGTGGGATTATAGCTACGATCGCGTACCTTACTACGGCACAAACACA
CCGATTGACGAATGTTATGAATGTGGTTTCACCGGCGAATTTGAATGTACCAGCAAAGGTTTTGTCTGCCCGAAATGTGG
CAATCACGACAGCACAAAAGTGTCTGTCACTCGCCGCGTCTGTGGCTATCTAGGCAGTCCTGATGCCCGCCCATTTAATG
CGGGAAAACAGGAAGAAGTGAAGAGAAGAGTTAAACACCTTTGA

Upstream 100 bases:

>100_bases
AAAAAGGTCTAAAACACTACATATTGTGTGTTGATTATCTTTTTAGATCTATATATAGTGCAATCCGCATTTCAAAAACA
CTATATATTGGAGCTATATC

Downstream 100 bases:

>100_bases
TTAACACGATAGCAAAAGCACGCATTTTTTAATGCGTGCTTTTTGTTTCCAACTTTGGCATTCCTAAAAATCTCCGCTAA
AATAACCGCACTTTTTCTTA

Product: anaerobic ribonucleoside triphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 707; Mature: 706

Protein sequence:

>707_residues
MSNFGVIKRDGSRAEFEIQRIINAIKKAASAVNISDEFYCHQIGQEVGNEIFTRHQGEIDINQIQKIVEDKLMASRYPEV
ARAYIEYRHDRDLAREKRSQLTKEIEGLIEQSNVELLNENANKDAKVIPTQRDLLAGIVAKHYAKHNILPRDVVEAHEKG
EIHYHDLDYAPFFPMFNCMLVDLEGMLSRGFKMGNAEIEPPKSIGTATAVTAQIIAQVASHIYGGTTINRIDEVLSPYVQ
ISYEKHLKHAQEWNVPDVEGYAKALIEKECFDAFQSLEYEVNTLHTSNGQTPFVTFGFGLGTSWQSRLIQQAILKNRIRG
LGKNHKTPVFPKLVFTIKKGLNQNKGDPNYDIKQLALECASKRMYPDILNYDQVVKVTGSFKAPMGCRSFLGAYEEKGHE
IHDGRNNLGVVSLNLPRIALESKNEEDFYRTLDERLAIAKKALMTRIARLENTKARVAPILYMEGACGVRLKADENVAQI
FKNGRASISLGYIGIHETINALYNKGHIFDDEQLREKGIAIVRHLSEAVKRWQKETGYAFSLYSTPSENLCDRFCRLDTK
KFGVIEGVTDKGYYTNSYHLDVEKKVNPYDKLDFEMTYPPLASGGFICYGEYPNIQHNLKALEDVWDYSYDRVPYYGTNT
PIDECYECGFTGEFECTSKGFVCPKCGNHDSTKVSVTRRVCGYLGSPDARPFNAGKQEEVKRRVKHL

Sequences:

>Translated_707_residues
MSNFGVIKRDGSRAEFEIQRIINAIKKAASAVNISDEFYCHQIGQEVGNEIFTRHQGEIDINQIQKIVEDKLMASRYPEV
ARAYIEYRHDRDLAREKRSQLTKEIEGLIEQSNVELLNENANKDAKVIPTQRDLLAGIVAKHYAKHNILPRDVVEAHEKG
EIHYHDLDYAPFFPMFNCMLVDLEGMLSRGFKMGNAEIEPPKSIGTATAVTAQIIAQVASHIYGGTTINRIDEVLSPYVQ
ISYEKHLKHAQEWNVPDVEGYAKALIEKECFDAFQSLEYEVNTLHTSNGQTPFVTFGFGLGTSWQSRLIQQAILKNRIRG
LGKNHKTPVFPKLVFTIKKGLNQNKGDPNYDIKQLALECASKRMYPDILNYDQVVKVTGSFKAPMGCRSFLGAYEEKGHE
IHDGRNNLGVVSLNLPRIALESKNEEDFYRTLDERLAIAKKALMTRIARLENTKARVAPILYMEGACGVRLKADENVAQI
FKNGRASISLGYIGIHETINALYNKGHIFDDEQLREKGIAIVRHLSEAVKRWQKETGYAFSLYSTPSENLCDRFCRLDTK
KFGVIEGVTDKGYYTNSYHLDVEKKVNPYDKLDFEMTYPPLASGGFICYGEYPNIQHNLKALEDVWDYSYDRVPYYGTNT
PIDECYECGFTGEFECTSKGFVCPKCGNHDSTKVSVTRRVCGYLGSPDARPFNAGKQEEVKRRVKHL
>Mature_706_residues
SNFGVIKRDGSRAEFEIQRIINAIKKAASAVNISDEFYCHQIGQEVGNEIFTRHQGEIDINQIQKIVEDKLMASRYPEVA
RAYIEYRHDRDLAREKRSQLTKEIEGLIEQSNVELLNENANKDAKVIPTQRDLLAGIVAKHYAKHNILPRDVVEAHEKGE
IHYHDLDYAPFFPMFNCMLVDLEGMLSRGFKMGNAEIEPPKSIGTATAVTAQIIAQVASHIYGGTTINRIDEVLSPYVQI
SYEKHLKHAQEWNVPDVEGYAKALIEKECFDAFQSLEYEVNTLHTSNGQTPFVTFGFGLGTSWQSRLIQQAILKNRIRGL
GKNHKTPVFPKLVFTIKKGLNQNKGDPNYDIKQLALECASKRMYPDILNYDQVVKVTGSFKAPMGCRSFLGAYEEKGHEI
HDGRNNLGVVSLNLPRIALESKNEEDFYRTLDERLAIAKKALMTRIARLENTKARVAPILYMEGACGVRLKADENVAQIF
KNGRASISLGYIGIHETINALYNKGHIFDDEQLREKGIAIVRHLSEAVKRWQKETGYAFSLYSTPSENLCDRFCRLDTKK
FGVIEGVTDKGYYTNSYHLDVEKKVNPYDKLDFEMTYPPLASGGFICYGEYPNIQHNLKALEDVWDYSYDRVPYYGTNTP
IDECYECGFTGEFECTSKGFVCPKCGNHDSTKVSVTRRVCGYLGSPDARPFNAGKQEEVKRRVKHL

Specific function: Unknown

COG id: COG1328

COG function: function code F; Oxygen-sensitive ribonucleoside-triphosphate reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glycine radical domain

Homologues:

Organism=Escherichia coli, GI1790686, Length=704, Percent_Identity=77.5568181818182, Blast_Score=1170, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDD_HAEIN (P43752)

Other databases:

- EMBL:   L42023
- PIR:   A64047
- RefSeq:   NP_438248.1
- ProteinModelPortal:   P43752
- SMR:   P43752
- GeneID:   950970
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0075
- NMPDR:   fig|71421.1.peg.74
- TIGR:   HI_0075
- HOGENOM:   HBG297080
- OMA:   NNTRGEE
- ProtClustDB:   PRK09263
- BioCyc:   HINF71421:HI_0075-MONOMER
- BRENDA:   1.17.4.2
- InterPro:   IPR005144
- InterPro:   IPR001150
- InterPro:   IPR019777
- InterPro:   IPR012833
- TIGRFAMs:   TIGR02487

Pfam domain/function: PF03477 ATP-cone; PF01228 Gly_radical

EC number: =1.17.4.2

Molecular weight: Translated: 80234; Mature: 80103

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: PS51161 ATP_CONE; PS00850 GLY_RADICAL_1; PS51149 GLY_RADICAL_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNFGVIKRDGSRAEFEIQRIINAIKKAASAVNISDEFYCHQIGQEVGNEIFTRHQGEID
CCCCCCEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
INQIQKIVEDKLMASRYPEVARAYIEYRHDRDLAREKRSQLTKEIEGLIEQSNVELLNEN
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCC
ANKDAKVIPTQRDLLAGIVAKHYAKHNILPRDVVEAHEKGEIHYHDLDYAPFFPMFNCML
CCCCCEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEECCCCCCHHHHHHHHH
VDLEGMLSRGFKMGNAEIEPPKSIGTATAVTAQIIAQVASHIYGGTTINRIDEVLSPYVQ
HHHHHHHHCCCCCCCCCCCCCHHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHE
ISYEKHLKHAQEWNVPDVEGYAKALIEKECFDAFQSLEYEVNTLHTSNGQTPFVTFGFGL
ECHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCEEEEECCC
GTSWQSRLIQQAILKNRIRGLGKNHKTPVFPKLVFTIKKGLNQNKGDPNYDIKQLALECA
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
SKRMYPDILNYDQVVKVTGSFKAPMGCRSFLGAYEEKGHEIHDGRNNLGVVSLNLPRIAL
HHCCCHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEE
ESKNEEDFYRTLDERLAIAKKALMTRIARLENTKARVAPILYMEGACGVRLKADENVAQI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEECCCCCEEEECCCHHHHH
FKNGRASISLGYIGIHETINALYNKGHIFDDEQLREKGIAIVRHLSEAVKRWQKETGYAF
HHCCCCEEEEEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
SLYSTPSENLCDRFCRLDTKKFGVIEGVTDKGYYTNSYHLDVEKKVNPYDKLDFEMTYPP
EEECCCCHHHHHHHHHCCCCCCCEEECCCCCCEECCEEEEEECCCCCCCCCCCCEECCCC
LASGGFICYGEYPNIQHNLKALEDVWDYSYDRVPYYGTNTPIDECYECGFTGEFECTSKG
CCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCC
FVCPKCGNHDSTKVSVTRRVCGYLGSPDARPFNAGKQEEVKRRVKHL
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
SNFGVIKRDGSRAEFEIQRIINAIKKAASAVNISDEFYCHQIGQEVGNEIFTRHQGEID
CCCCCEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
INQIQKIVEDKLMASRYPEVARAYIEYRHDRDLAREKRSQLTKEIEGLIEQSNVELLNEN
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCC
ANKDAKVIPTQRDLLAGIVAKHYAKHNILPRDVVEAHEKGEIHYHDLDYAPFFPMFNCML
CCCCCEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEECCCCCCHHHHHHHHH
VDLEGMLSRGFKMGNAEIEPPKSIGTATAVTAQIIAQVASHIYGGTTINRIDEVLSPYVQ
HHHHHHHHCCCCCCCCCCCCCHHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHE
ISYEKHLKHAQEWNVPDVEGYAKALIEKECFDAFQSLEYEVNTLHTSNGQTPFVTFGFGL
ECHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCEEEEECCC
GTSWQSRLIQQAILKNRIRGLGKNHKTPVFPKLVFTIKKGLNQNKGDPNYDIKQLALECA
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
SKRMYPDILNYDQVVKVTGSFKAPMGCRSFLGAYEEKGHEIHDGRNNLGVVSLNLPRIAL
HHCCCHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEE
ESKNEEDFYRTLDERLAIAKKALMTRIARLENTKARVAPILYMEGACGVRLKADENVAQI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEECCCCCEEEECCCHHHHH
FKNGRASISLGYIGIHETINALYNKGHIFDDEQLREKGIAIVRHLSEAVKRWQKETGYAF
HHCCCCEEEEEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
SLYSTPSENLCDRFCRLDTKKFGVIEGVTDKGYYTNSYHLDVEKKVNPYDKLDFEMTYPP
EEECCCCHHHHHHHHHCCCCCCCEEECCCCCCEECCEEEEEECCCCCCCCCCCCEECCCC
LASGGFICYGEYPNIQHNLKALEDVWDYSYDRVPYYGTNTPIDECYECGFTGEFECTSKG
CCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCC
FVCPKCGNHDSTKVSVTRRVCGYLGSPDARPFNAGKQEEVKRRVKHL
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800