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The map label for this gene is uvrC [H]

Identifier: 16272031

GI number: 16272031

Start: 57655

End: 59484

Strand: Reverse

Name: uvrC [H]

Synonym: HI0057

Alternate gene names: 16272031

Gene position: 59484-57655 (Counterclockwise)

Preceding gene: 16272032

Following gene: 16272030

Centisome position: 3.25

GC content: 39.07

Gene sequence:

>1830_bases
ATGTTTGATGCTAAAAAATTCCTCACTGATGTCTCTCACGAACCTGGTGTTTATCGTATGTATGACGATAAAGATCAGGT
TATTTATGTTGGGAAAGCAAAGGATTTAAAGAAACGTCTTTCAAGCTATTTTCGTAAAAATCTGAGCAGTAAAAAAACAG
AGGCGTTGGTGGCGTCAATTCATCATATTGACACCACGCTAACTTCATCTGAAACGGAAGCTTTACTGCTAGAGCATAAT
TTTATCAAGCTTTATCAGCCTCGTTATAACGTATTATTGCGTGATGATAAATCCTATCCATTTATTTTATTAACCAAAGA
ACGCCACCAAAGAATTACTTCTTATCGTGGTTCTAAAAAATTTGCAGGTGAATATTTTGGGCCTTATCCTCACGCGGGAG
CCGTGCGTGAAACGTTATCGCTTTTGCAAAAACTTTTCCCTGTTCGCCAATGTGAAAATTCCGTTTATTCCAACCGCTCT
CGTCCTTGTTTGCAGTATCAAATTGGGCGTTGTTCTGCACCTTGTGTACAGGGATATGTTTCCGATGAAGAATATAATCA
GCAAGTTGAATTAGCTCGCTTATTTTTACAAGGCAAAGATCAACAGGTGTTAGATTATTTAATCGGTAAAATGGAGCAGG
CAAGCAGAAATTTAGATTTTGAACAGGCTGCTCGTTATCGCGATCAAATTCAGGCTGTGCGTTCGGTTATAGAAAAACAA
TTTGTATCCAATGAACGTTTAGATGATATGGATATTATGTCTATCGCTTACCAACACGGGTTAGCCTGTGTACAGGTGAT
GTTTATTCGTCAAGGAAAAGTGCTAGGCAATCGCAGTTATTTCCCAAAAGTCCCCGCCAATACGGATTTATCGGAACTTA
CCGAAACTTTTGTGGGGCAATTTTATTTACAAGGTCATCAAGGACGAAGTATCCCGAATAGCATTATTGTGGATCGTCAA
TTAGCTGAAAAATCGGAGCTTGAGCAACTTCTTAGCGAGCAAGCGGGCAGAAAAGTGACGATTCAAGAAAGCGTAAAAGG
CGATAAAAGTAAATACTTACAGCTCGCACAAGTTAATGCTAAAGCGGCTTTAAATGTACAACTTAAACAATCTTCACGAA
TGTCAGAGCGTTATCAAGCGTTGTGTGATCTGTTAAATCTTCCTAAAATTAAGCGTATGGAATGTTTCGATATAAGCCAC
ACGATGGGAAATCAAACAGTAGCATCTTGTGTTGTTTTTAATAAAGAAGGTCCACTAAAATCTGATTATCGTCGTTTTAA
TATTGAAGGCATTACTGGCGGGGATGATTATGCTGCGATGGAACAAGTGTTGCAGAAACGTTATGAGCGTGATTTAGAAG
AAGATAAAATTCCCGATATTATTTTTATTGATGGTGGAAAAGGGCAATTAAATCGTGCGCTGAATGTATTCCAACATCTT
CAAGTAAAATGGGATAAAAATAGACCGCACTTAATTGGCGTGGCAAAAGGTGTGGATCGTCGAGCAGGACAGGAAGTACT
GATCATCAGCAAACAAGACCGCGAAATTCATTTGCCTGATGATAGTTTGGCATTGCATTTGATTCAACACATCCGTGATG
AAAGCCATAATCACGCAATAAGCGGACACCGTAAAAAACGTCAAAAAGCCTTTACACAAAGTGGTTTAGAAACCATTGAA
GGTGTGGGAGCTAAACGTCGTCAGGCTTTACTGAAATATCTTGGTGGTTTACAAGGTGTGAAAAAGGCGACCTTAGATGA
AATAGCCTCTGTACCGGGCATTTCCCCTAAACTTGCTGAAAGGATTTTTGAAACGCTTAAAAACGACTAA

Upstream 100 bases:

>100_bases
GAACGTATTCACGTAGAACTTGCGAAAGAAGTGCCTGCAGTGGGGGTGGATACCGCCGAAGATTTGGAAAAAGTGCGGGC
AATTTTAGCGGCGAATTAAA

Downstream 100 bases:

>100_bases
TCAATCATTTCTCAAATATAAATAACGATTGCTTTTCGTCATAAAGCCATTATGATCTGTATTTTCGGATTTATTTAACT
CAATTATAGGAAAAATTATG

Product: excinuclease ABC subunit C

Products: NA

Alternate protein names: Protein uvrC; Excinuclease ABC subunit C [H]

Number of amino acids: Translated: 609; Mature: 609

Protein sequence:

>609_residues
MFDAKKFLTDVSHEPGVYRMYDDKDQVIYVGKAKDLKKRLSSYFRKNLSSKKTEALVASIHHIDTTLTSSETEALLLEHN
FIKLYQPRYNVLLRDDKSYPFILLTKERHQRITSYRGSKKFAGEYFGPYPHAGAVRETLSLLQKLFPVRQCENSVYSNRS
RPCLQYQIGRCSAPCVQGYVSDEEYNQQVELARLFLQGKDQQVLDYLIGKMEQASRNLDFEQAARYRDQIQAVRSVIEKQ
FVSNERLDDMDIMSIAYQHGLACVQVMFIRQGKVLGNRSYFPKVPANTDLSELTETFVGQFYLQGHQGRSIPNSIIVDRQ
LAEKSELEQLLSEQAGRKVTIQESVKGDKSKYLQLAQVNAKAALNVQLKQSSRMSERYQALCDLLNLPKIKRMECFDISH
TMGNQTVASCVVFNKEGPLKSDYRRFNIEGITGGDDYAAMEQVLQKRYERDLEEDKIPDIIFIDGGKGQLNRALNVFQHL
QVKWDKNRPHLIGVAKGVDRRAGQEVLIISKQDREIHLPDDSLALHLIQHIRDESHNHAISGHRKKRQKAFTQSGLETIE
GVGAKRRQALLKYLGGLQGVKKATLDEIASVPGISPKLAERIFETLKND

Sequences:

>Translated_609_residues
MFDAKKFLTDVSHEPGVYRMYDDKDQVIYVGKAKDLKKRLSSYFRKNLSSKKTEALVASIHHIDTTLTSSETEALLLEHN
FIKLYQPRYNVLLRDDKSYPFILLTKERHQRITSYRGSKKFAGEYFGPYPHAGAVRETLSLLQKLFPVRQCENSVYSNRS
RPCLQYQIGRCSAPCVQGYVSDEEYNQQVELARLFLQGKDQQVLDYLIGKMEQASRNLDFEQAARYRDQIQAVRSVIEKQ
FVSNERLDDMDIMSIAYQHGLACVQVMFIRQGKVLGNRSYFPKVPANTDLSELTETFVGQFYLQGHQGRSIPNSIIVDRQ
LAEKSELEQLLSEQAGRKVTIQESVKGDKSKYLQLAQVNAKAALNVQLKQSSRMSERYQALCDLLNLPKIKRMECFDISH
TMGNQTVASCVVFNKEGPLKSDYRRFNIEGITGGDDYAAMEQVLQKRYERDLEEDKIPDIIFIDGGKGQLNRALNVFQHL
QVKWDKNRPHLIGVAKGVDRRAGQEVLIISKQDREIHLPDDSLALHLIQHIRDESHNHAISGHRKKRQKAFTQSGLETIE
GVGAKRRQALLKYLGGLQGVKKATLDEIASVPGISPKLAERIFETLKND
>Mature_609_residues
MFDAKKFLTDVSHEPGVYRMYDDKDQVIYVGKAKDLKKRLSSYFRKNLSSKKTEALVASIHHIDTTLTSSETEALLLEHN
FIKLYQPRYNVLLRDDKSYPFILLTKERHQRITSYRGSKKFAGEYFGPYPHAGAVRETLSLLQKLFPVRQCENSVYSNRS
RPCLQYQIGRCSAPCVQGYVSDEEYNQQVELARLFLQGKDQQVLDYLIGKMEQASRNLDFEQAARYRDQIQAVRSVIEKQ
FVSNERLDDMDIMSIAYQHGLACVQVMFIRQGKVLGNRSYFPKVPANTDLSELTETFVGQFYLQGHQGRSIPNSIIVDRQ
LAEKSELEQLLSEQAGRKVTIQESVKGDKSKYLQLAQVNAKAALNVQLKQSSRMSERYQALCDLLNLPKIKRMECFDISH
TMGNQTVASCVVFNKEGPLKSDYRRFNIEGITGGDDYAAMEQVLQKRYERDLEEDKIPDIIFIDGGKGQLNRALNVFQHL
QVKWDKNRPHLIGVAKGVDRRAGQEVLIISKQDREIHLPDDSLALHLIQHIRDESHNHAISGHRKKRQKAFTQSGLETIE
GVGAKRRQALLKYLGGLQGVKKATLDEIASVPGISPKLAERIFETLKND

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision [H]

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI87081999, Length=607, Percent_Identity=65.8978583196046, Blast_Score=844, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR001943
- InterPro:   IPR009055
- InterPro:   IPR004791
- InterPro:   IPR001162
- InterPro:   IPR000305 [H]

Pfam domain/function: PF01541 GIY-YIG; PF02151 UVR; PF08459 UvrC_HhH_N [H]

EC number: NA

Molecular weight: Translated: 69610; Mature: 69610

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS50151 UVR ; PS50164 UVRC_1 ; PS50165 UVRC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDAKKFLTDVSHEPGVYRMYDDKDQVIYVGKAKDLKKRLSSYFRKNLSSKKTEALVASI
CCCHHHHHHHCCCCCCEEEEECCCCCEEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHH
HHIDTTLTSSETEALLLEHNFIKLYQPRYNVLLRDDKSYPFILLTKERHQRITSYRGSKK
HHHHHHCCCCCCCEEEEECCHHEEECCCCCEEEECCCCCCEEEEEHHHHHHHHHCCCCCH
FAGEYFGPYPHAGAVRETLSLLQKLFPVRQCENSVYSNRSRPCLQYQIGRCSAPCVQGYV
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHHCCC
SDEEYNQQVELARLFLQGKDQQVLDYLIGKMEQASRNLDFEQAARYRDQIQAVRSVIEKQ
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
FVSNERLDDMDIMSIAYQHGLACVQVMFIRQGKVLGNRSYFPKVPANTDLSELTETFVGQ
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCHHHHHHHHHHH
FYLQGHQGRSIPNSIIVDRQLAEKSELEQLLSEQAGRKVTIQESVKGDKSKYLQLAQVNA
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHCCCHHHHHHHHHCCC
KAALNVQLKQSSRMSERYQALCDLLNLPKIKRMECFDISHTMGNQTVASCVVFNKEGPLK
CEEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCHHEEHHHHCCCHHHHHEEEECCCCCCC
SDYRRFNIEGITGGDDYAAMEQVLQKRYERDLEEDKIPDIIFIDGGKGQLNRALNVFQHL
CCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCHHCCCCCEEEEECCCHHHHHHHHHHHHH
QVKWDKNRPHLIGVAKGVDRRAGQEVLIISKQDREIHLPDDSLALHLIQHIRDESHNHAI
HHEECCCCCCEEEECCCCCHHCCCEEEEEECCCCEEECCCHHHHHHHHHHHHCCCCCCCC
SGHRKKRQKAFTQSGLETIEGVGAKRRQALLKYLGGLQGVKKATLDEIASVPGISPKLAE
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHH
RIFETLKND
HHHHHHCCC
>Mature Secondary Structure
MFDAKKFLTDVSHEPGVYRMYDDKDQVIYVGKAKDLKKRLSSYFRKNLSSKKTEALVASI
CCCHHHHHHHCCCCCCEEEEECCCCCEEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHH
HHIDTTLTSSETEALLLEHNFIKLYQPRYNVLLRDDKSYPFILLTKERHQRITSYRGSKK
HHHHHHCCCCCCCEEEEECCHHEEECCCCCEEEECCCCCCEEEEEHHHHHHHHHCCCCCH
FAGEYFGPYPHAGAVRETLSLLQKLFPVRQCENSVYSNRSRPCLQYQIGRCSAPCVQGYV
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHHCCC
SDEEYNQQVELARLFLQGKDQQVLDYLIGKMEQASRNLDFEQAARYRDQIQAVRSVIEKQ
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
FVSNERLDDMDIMSIAYQHGLACVQVMFIRQGKVLGNRSYFPKVPANTDLSELTETFVGQ
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCHHHHHHHHHHH
FYLQGHQGRSIPNSIIVDRQLAEKSELEQLLSEQAGRKVTIQESVKGDKSKYLQLAQVNA
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHCCCHHHHHHHHHCCC
KAALNVQLKQSSRMSERYQALCDLLNLPKIKRMECFDISHTMGNQTVASCVVFNKEGPLK
CEEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCHHEEHHHHCCCHHHHHEEEECCCCCCC
SDYRRFNIEGITGGDDYAAMEQVLQKRYERDLEEDKIPDIIFIDGGKGQLNRALNVFQHL
CCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCHHCCCCCEEEEECCCHHHHHHHHHHHHH
QVKWDKNRPHLIGVAKGVDRRAGQEVLIISKQDREIHLPDDSLALHLIQHIRDESHNHAI
HHEECCCCCCEEEECCCCCHHCCCEEEEEECCCCEEECCCHHHHHHHHHHHHCCCCCCCC
SGHRKKRQKAFTQSGLETIEGVGAKRRQALLKYLGGLQGVKKATLDEIASVPGISPKLAE
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHH
RIFETLKND
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA