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The map label for this gene is rbsK [H]

Identifier: 99082718

GI number: 99082718

Start: 3049119

End: 3049991

Strand: Direct

Name: rbsK [H]

Synonym: TM1040_2878

Alternate gene names: 99082718

Gene position: 3049119-3049991 (Clockwise)

Preceding gene: 99082717

Following gene: 99082724

Centisome position: 95.26

GC content: 60.82

Gene sequence:

>873_bases
ATGGCGATCTGGAACCTTGGGTCGATCAACATCGACATGGTCTATTCGCTGCCGCATATGCCGCAGCCGGGCGAGACGCT
GGCAGCCACTTCCTTTGATCAGGGTCTGGGCGGCAAGGGCGCAAATATGTCGGTTGCCGCCGCCCGCGCTGGGGCGCATG
CCTGCCATATCGGGGCCATTGGTCCAGAGGGGAAATGGTGTGTGGATCGGTTGATGGAGTACGGTGTCGATACGCGCCAT
ATCGTGCAAAGCGATACCGCGACCGGTCATGCCATCATCGCTGTGGATCCGGCCGGTGAAAATCAGATCATCCTCTATCC
CGGTGCTAACCGTGGGCTTGGTGCCGATCAGATCGGCCAAGCACTCAGCGCGGCAAACGCAGGGGATATTCTGCTGATGC
AGAATGAGACCAACATGCAGGCCGAGGCCGCAGAGATGGGGCGCAAACTGGGGCTGCGCGTCGCATATGCGGCGGCGCCT
TTTGATGCGGCAGCGGTTCAGGCGGTTTTGCCCTTTGTGGATCTCTTGTTTCTCAACGAGGTCGAGGCGGCACAGCTTCA
GGACGCCACAGGAAAACCACCTCAGGATCTGGGTGTCGACGATGTGATCGTGACACTCGGGGCTGAAGGCGCGCGCCATT
TTGACGGTCGCACCGGCGCTGTGAGCGATGTGGCTGCGCAGAAGGTGACTGCAGTGGATACCACCGGGGCGGGGGACACA
TTCACCGGATATGTTCTGGCTGCGCTGGATCGCGGATTACCGATGGCGCAGGCCATGGCGCAGGCCTCGCGGGCCGGAGC
CTTGATGGTTACACGTCACGGAGCGGCAGATGTTATCCCGGACCTCAAAGAGGTTCAGGACGCCAAATTCTGA

Upstream 100 bases:

>100_bases
CCGATCCAGATCTGCTCCACCACCTCGACCGCAAATGACGTGCTGAACATGGCCGTTCTTGCGGCCTGCAACATCGGTTG
AACCAGAAGGGAGGCTGCTC

Downstream 100 bases:

>100_bases
CGTCCCTGTTCTACAGAACCACCAAGAAGGGGGCCCTAGCGGCCCCTTTTTTATGAGTTATCAAAACCCGTAGCTTCCAA
TGAAAGGCGCATCGCGCCCC

Product: PfkB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MAIWNLGSINIDMVYSLPHMPQPGETLAATSFDQGLGGKGANMSVAAARAGAHACHIGAIGPEGKWCVDRLMEYGVDTRH
IVQSDTATGHAIIAVDPAGENQIILYPGANRGLGADQIGQALSAANAGDILLMQNETNMQAEAAEMGRKLGLRVAYAAAP
FDAAAVQAVLPFVDLLFLNEVEAAQLQDATGKPPQDLGVDDVIVTLGAEGARHFDGRTGAVSDVAAQKVTAVDTTGAGDT
FTGYVLAALDRGLPMAQAMAQASRAGALMVTRHGAADVIPDLKEVQDAKF

Sequences:

>Translated_290_residues
MAIWNLGSINIDMVYSLPHMPQPGETLAATSFDQGLGGKGANMSVAAARAGAHACHIGAIGPEGKWCVDRLMEYGVDTRH
IVQSDTATGHAIIAVDPAGENQIILYPGANRGLGADQIGQALSAANAGDILLMQNETNMQAEAAEMGRKLGLRVAYAAAP
FDAAAVQAVLPFVDLLFLNEVEAAQLQDATGKPPQDLGVDDVIVTLGAEGARHFDGRTGAVSDVAAQKVTAVDTTGAGDT
FTGYVLAALDRGLPMAQAMAQASRAGALMVTRHGAADVIPDLKEVQDAKF
>Mature_289_residues
AIWNLGSINIDMVYSLPHMPQPGETLAATSFDQGLGGKGANMSVAAARAGAHACHIGAIGPEGKWCVDRLMEYGVDTRHI
VQSDTATGHAIIAVDPAGENQIILYPGANRGLGADQIGQALSAANAGDILLMQNETNMQAEAAEMGRKLGLRVAYAAAPF
DAAAVQAVLPFVDLLFLNEVEAAQLQDATGKPPQDLGVDDVIVTLGAEGARHFDGRTGAVSDVAAQKVTAVDTTGAGDTF
TGYVLAALDRGLPMAQAMAQASRAGALMVTRHGAADVIPDLKEVQDAKF

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=252, Percent_Identity=32.5396825396825, Blast_Score=105, Evalue=3e-23,
Organism=Escherichia coli, GI1790193, Length=297, Percent_Identity=35.016835016835, Blast_Score=108, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17532905, Length=297, Percent_Identity=33.3333333333333, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI20128807, Length=268, Percent_Identity=33.955223880597, Blast_Score=100, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24583886, Length=294, Percent_Identity=28.9115646258503, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 29943; Mature: 29812

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIWNLGSINIDMVYSLPHMPQPGETLAATSFDQGLGGKGANMSVAAARAGAHACHIGAI
CCEEECCCCEEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCEEEHHHCCCCEEEEECC
GPEGKWCVDRLMEYGVDTRHIVQSDTATGHAIIAVDPAGENQIILYPGANRGLGADQIGQ
CCCCHHHHHHHHHCCCCHHEEEECCCCCCEEEEEECCCCCCEEEEECCCCCCCCHHHHHH
ALSAANAGDILLMQNETNMQAEAAEMGRKLGLRVAYAAAPFDAAAVQAVLPFVDLLFLNE
HHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHCC
VEAAQLQDATGKPPQDLGVDDVIVTLGAEGARHFDGRTGAVSDVAAQKVTAVDTTGAGDT
CHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHEEEEECCCCCCC
FTGYVLAALDRGLPMAQAMAQASRAGALMVTRHGAADVIPDLKEVQDAKF
HHHHHHHHHHCCCCHHHHHHHHHHCCEEEEEECCCHHHCCCHHHHHCCCC
>Mature Secondary Structure 
AIWNLGSINIDMVYSLPHMPQPGETLAATSFDQGLGGKGANMSVAAARAGAHACHIGAI
CEEECCCCEEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCEEEHHHCCCCEEEEECC
GPEGKWCVDRLMEYGVDTRHIVQSDTATGHAIIAVDPAGENQIILYPGANRGLGADQIGQ
CCCCHHHHHHHHHCCCCHHEEEECCCCCCEEEEEECCCCCCEEEEECCCCCCCCHHHHHH
ALSAANAGDILLMQNETNMQAEAAEMGRKLGLRVAYAAAPFDAAAVQAVLPFVDLLFLNE
HHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHCC
VEAAQLQDATGKPPQDLGVDDVIVTLGAEGARHFDGRTGAVSDVAAQKVTAVDTTGAGDT
CHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHEEEEECCCCCCC
FTGYVLAALDRGLPMAQAMAQASRAGALMVTRHGAADVIPDLKEVQDAKF
HHHHHHHHHHCCCCHHHHHHHHHHCCEEEEEECCCHHHCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]