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The map label for this gene is yleA [C]

Identifier: 99082650

GI number: 99082650

Start: 2973760

End: 2975025

Strand: Direct

Name: yleA [C]

Synonym: TM1040_2810

Alternate gene names: 99082650

Gene position: 2973760-2975025 (Clockwise)

Preceding gene: 99082649

Following gene: 99082651

Centisome position: 92.9

GC content: 58.61

Gene sequence:

>1266_bases
ATGAGCAACGCGCCAAAATTCACAACGCTCGGCTGTCGGCTCAATGCCTATGAAACAGAGGCCATGAAGGAGCTCAGCCG
CCAGGCGGGCCTTGAGGGTGCCGTAGTGGTCAATACATGTGCCGTAACCGCCGAGGCAGTGCGCAAGGCGCGTCAGGAAA
TTCGCAAACTGCGGCGCGATCACCCGGATGCGCCCATTATCGTCACCGGATGTGCCGCCCAGACCGAGCCGGAAACCTTT
GCCGCGATGAGCGAAGTCACGCAGGTGATCGGCAACACCGAAAAGATGCAGCCCGAAACATGGCAGCGCATGGCCAAGGG
GCTGGATTTCATCGGCGCCACCGAAAAAGTTCTAGTGGACGACATCATGTCGGTGACAGAGACCGCAAGTCATCTGATTG
ATGGGTTCGGGACGCGGTCCAGGGCCTATGTGCAGGTCCAAAACGGCTGCGATCATCGCTGTACCTTTTGCATCATCCCC
TATGGACGCGGCAATTCCCGCTCCGTGCCTGCCGGCGTTGTTGTGGATCAGATCAAGCGTCTGGTCGACAAAGGCTACAA
CGAGGTGGTGCTGACCGGGGTCGATCTGACCAGCTGGGGTGCGGATTTGCCCGCAAGTCCCAAGCTGGGAGACCTTGTGA
TGCGAATCTTGAAGCTCGTCCCAGATTTGCCCCGTCTGCGTATCTCGTCGATCGATTCGATCGAAGTGGACGAAAACCTG
ATGCAGGCCATCGCCACAGAGCCACGCCTGATGCCCCACCTGCATCTGAGCCTGCAACATGGCGATGATCTCATTCTAAA
GCGGATGAAACGGCGCCATCTGCGCGATGACGCCATTCGGTTCACGGAGGAAGCCCGCAAGCTGCGTCCGCAGATGACCT
TTGGCGCGGATATCATCGCCGGCTTTCCGACCGAAACCGAATCGCATTTTGAAAACTCGCTCAAACTCGTAACCGAATGC
GACCTCACCTGGCTGCATGTCTTCCCCTATTCCAAGCGCGAGGGAACCCCAGCCGCCAAGATCCCGTCACAGGTCAATGG
CAATGTGATCAAGGAACGTGCTGCGCGCCTGCGTGCCATCGGCGAAGCACAGATTGCCAGACACCTCTCCGAGCAGATCG
GTCGTCAACATAGCATCTTGATGGAAAACCCTCACATGGGGCGCACAGAACAGTTCACCGAAGTGCGCTTTGCCACACCA
CAGACCGAAGGCGCCCTCGTTCAGGCGCAGATCACCGGGAGCGATGGGCTGCAGCTCACCGCCTGA

Upstream 100 bases:

>100_bases
TGTGGATCGATTGGCGCGACGATGGGGTCTGGATGACCGGACCAACAATGCATGTCGCCAATGGCAGCTTTACACGGCAA
TTCCTCGAAAGCTTGTCCGA

Downstream 100 bases:

>100_bases
CGCCGGGAGGTCGTCCAATGGCGCTGATACTGTTTCTGCATGGCCCCTCCAGCAGCGGCAAATCCACACTCGCCAAAGCG
ATCAGAGAGGCTTCCTCCCG

Product: MiaB-like tRNA modifying enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MSNAPKFTTLGCRLNAYETEAMKELSRQAGLEGAVVVNTCAVTAEAVRKARQEIRKLRRDHPDAPIIVTGCAAQTEPETF
AAMSEVTQVIGNTEKMQPETWQRMAKGLDFIGATEKVLVDDIMSVTETASHLIDGFGTRSRAYVQVQNGCDHRCTFCIIP
YGRGNSRSVPAGVVVDQIKRLVDKGYNEVVLTGVDLTSWGADLPASPKLGDLVMRILKLVPDLPRLRISSIDSIEVDENL
MQAIATEPRLMPHLHLSLQHGDDLILKRMKRRHLRDDAIRFTEEARKLRPQMTFGADIIAGFPTETESHFENSLKLVTEC
DLTWLHVFPYSKREGTPAAKIPSQVNGNVIKERAARLRAIGEAQIARHLSEQIGRQHSILMENPHMGRTEQFTEVRFATP
QTEGALVQAQITGSDGLQLTA

Sequences:

>Translated_421_residues
MSNAPKFTTLGCRLNAYETEAMKELSRQAGLEGAVVVNTCAVTAEAVRKARQEIRKLRRDHPDAPIIVTGCAAQTEPETF
AAMSEVTQVIGNTEKMQPETWQRMAKGLDFIGATEKVLVDDIMSVTETASHLIDGFGTRSRAYVQVQNGCDHRCTFCIIP
YGRGNSRSVPAGVVVDQIKRLVDKGYNEVVLTGVDLTSWGADLPASPKLGDLVMRILKLVPDLPRLRISSIDSIEVDENL
MQAIATEPRLMPHLHLSLQHGDDLILKRMKRRHLRDDAIRFTEEARKLRPQMTFGADIIAGFPTETESHFENSLKLVTEC
DLTWLHVFPYSKREGTPAAKIPSQVNGNVIKERAARLRAIGEAQIARHLSEQIGRQHSILMENPHMGRTEQFTEVRFATP
QTEGALVQAQITGSDGLQLTA
>Mature_420_residues
SNAPKFTTLGCRLNAYETEAMKELSRQAGLEGAVVVNTCAVTAEAVRKARQEIRKLRRDHPDAPIIVTGCAAQTEPETFA
AMSEVTQVIGNTEKMQPETWQRMAKGLDFIGATEKVLVDDIMSVTETASHLIDGFGTRSRAYVQVQNGCDHRCTFCIIPY
GRGNSRSVPAGVVVDQIKRLVDKGYNEVVLTGVDLTSWGADLPASPKLGDLVMRILKLVPDLPRLRISSIDSIEVDENLM
QAIATEPRLMPHLHLSLQHGDDLILKRMKRRHLRDDAIRFTEEARKLRPQMTFGADIIAGFPTETESHFENSLKLVTECD
LTWLHVFPYSKREGTPAAKIPSQVNGNVIKERAARLRAIGEAQIARHLSEQIGRQHSILMENPHMGRTEQFTEVRFATPQ
TEGALVQAQITGSDGLQLTA

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MTTase N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=406, Percent_Identity=25.3694581280788, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI28872784, Length=370, Percent_Identity=21.8918918918919, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI28872782, Length=370, Percent_Identity=21.8918918918919, Blast_Score=108, Evalue=7e-24,
Organism=Escherichia coli, GI1786882, Length=433, Percent_Identity=26.5588914549654, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1787057, Length=392, Percent_Identity=28.0612244897959, Blast_Score=148, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI17553146, Length=415, Percent_Identity=25.7831325301205, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI71996771, Length=241, Percent_Identity=28.6307053941909, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI21356207, Length=421, Percent_Identity=25.6532066508314, Blast_Score=148, Evalue=6e-36,
Organism=Drosophila melanogaster, GI19922432, Length=382, Percent_Identity=25.9162303664921, Blast_Score=124, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 46696; Mature: 46565

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNAPKFTTLGCRLNAYETEAMKELSRQAGLEGAVVVNTCAVTAEAVRKARQEIRKLRRD
CCCCCCEEEECEEECCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHC
HPDAPIIVTGCAAQTEPETFAAMSEVTQVIGNTEKMQPETWQRMAKGLDFIGATEKVLVD
CCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCHHHHHHH
DIMSVTETASHLIDGFGTRSRAYVQVQNGCDHRCTFCIIPYGRGNSRSVPAGVVVDQIKR
HHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHH
LVDKGYNEVVLTGVDLTSWGADLPASPKLGDLVMRILKLVPDLPRLRISSIDSIEVDENL
HHHCCCCEEEEEECCHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHH
MQAIATEPRLMPHLHLSLQHGDDLILKRMKRRHLRDDAIRFTEEARKLRPQMTFGADIIA
HHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEE
GFPTETESHFENSLKLVTECDLTWLHVFPYSKREGTPAAKIPSQVNGNVIKERAARLRAI
CCCCCCHHHHHHHHHHHEECCEEEEEEECCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHH
GEAQIARHLSEQIGRQHSILMENPHMGRTEQFTEVRFATPQTEGALVQAQITGSDGLQLT
HHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHEEEECCCCCCCCEEEEEEECCCCCEEC
A
C
>Mature Secondary Structure 
SNAPKFTTLGCRLNAYETEAMKELSRQAGLEGAVVVNTCAVTAEAVRKARQEIRKLRRD
CCCCCEEEECEEECCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHC
HPDAPIIVTGCAAQTEPETFAAMSEVTQVIGNTEKMQPETWQRMAKGLDFIGATEKVLVD
CCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCHHHHHHH
DIMSVTETASHLIDGFGTRSRAYVQVQNGCDHRCTFCIIPYGRGNSRSVPAGVVVDQIKR
HHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHH
LVDKGYNEVVLTGVDLTSWGADLPASPKLGDLVMRILKLVPDLPRLRISSIDSIEVDENL
HHHCCCCEEEEEECCHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHH
MQAIATEPRLMPHLHLSLQHGDDLILKRMKRRHLRDDAIRFTEEARKLRPQMTFGADIIA
HHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEE
GFPTETESHFENSLKLVTECDLTWLHVFPYSKREGTPAAKIPSQVNGNVIKERAARLRAI
CCCCCCHHHHHHHHHHHEECCEEEEEEECCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHH
GEAQIARHLSEQIGRQHSILMENPHMGRTEQFTEVRFATPQTEGALVQAQITGSDGLQLT
HHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHEEEECCCCCCCCEEEEEEECCCCCEEC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]