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The map label for this gene is gpmI

Identifier: 99082597

GI number: 99082597

Start: 2905615

End: 2907135

Strand: Reverse

Name: gpmI

Synonym: TM1040_2757

Alternate gene names: 99082597

Gene position: 2907135-2905615 (Counterclockwise)

Preceding gene: 99082599

Following gene: 99082596

Centisome position: 90.82

GC content: 61.14

Gene sequence:

>1521_bases
ATGACCACACCCAAACCCGTTGTACTTTGCATCCTTGATGGCTGGGGCAGCGCCGAACCGGGGCCTGCGAATGCGCCCTA
TCTTGCAAAGACACCGACGCTGGATGCGATCATGCAGAGCTGCCCGACCGCGCGGCTTGTGACGCATGGTCCAGATGTCG
GCCTGCCAAGCGGGCAAATGGGGAACTCCGAAGTCGGCCACACCAATATCGGCGCGGGTCGCGTGGTCGCGATGGATCTG
GGTCAGATCGACCTCGCGATCGAAGATGGGTCTTTCTACGATAACGACGCGCTTCAGGCGTTCATCGCCAAGCTGAAAGA
GACAGGTGGTGCTGCGCATCTGATGGGGCTGGTCTCGGATGGTGGCGTGCATGGCCATGTGACGCATATCCTGGCTGCGA
TCAAAGCGATCCGCGATGCGGGCGTCCCGGTCTGGCTGCACGCGATCACCGATGGGCGTGACGTGGCCCCGAAATCTGCG
CTCACCTATCTCGATCAACTGGAGGCCGGGATGGCGCCGGGCGCGCAGATTGCCACCGTCACCGGACGTTATTTCGCCAT
GGACCGCGATAATCGCTGGGAGCGGGTCTCTGAGGCCTATGACGCGATGGTAAAGGGCGCCGGTCAGTTCACCGCCGCCA
CCGCGAGGGACGCCGTCGAAAATGCCTATGGCCGCGATGAGCTTGATGAGTTTGTCAAGGCAACGGTGGTCGAGGGGTTT
GATGGTATCAAGGAAGGAGACGGTTTCTTCTGCCTGAACTTCCGCGCGGATCGCGCGCGGGAAATTCTGCGCGCTATTGG
TGAGCCAGGGTTTGCCGAGTTCGACACCGGTCCGCGTCCTGCACTGGCGGCGCTCTTGGGAATGGTGGAGTATTCTGAGG
GTCATAATGCCTATATGACCACTGCCTACCCCAAGCGCGCCATCGTCAACACGCTCGGCGAATGGGTGGCCAAACAGGGC
AAGCGCCAGTTCCGTCTCGCCGAGACCGAAAAGTACCCGCATGTGACCTTCTTCCTCAATGGTGGCAAGGAAACCCCCGA
GGTAGGCGAAGATCGCTTTATGCCCAAATCGCCCAAGGTGGCGACTTATGATCTGCAACCCGAGATGTCTGCGCCAGAAG
TCACCGCGAAATTCGTCGAAGCCATCCGGGCTGGCTATGACCTCATCGTGACCAACTACGCCAATCCCGACATGGTCGGC
CATACCGGTGATCTCGATGCAGCCATCAAGGCCTGCGAGGCGGTGGATCAGGGGCTTGGCGAGGTTGTCGCGGCCCTGAA
AGATGCAGGCGGGGCGATGATCGTGACCGCCGACCACGGCAACTGCGAGCTGATGGTTGATCCCGAAACCGGAGGGGCAC
ATACGGCCCATACCACCAATCTCGTGCCGGTGGCGCTTGTTGGTGGGCCAGAGGGGACAGCGCTGAAGGATGGGCGGCTT
GCGGATCTCGCGCCGACGCTTCTGGCACTGATGGGGCTCGATCAACCCGAAGAGATGACCGGAGAGAGCCTGCTCGTATG
A

Upstream 100 bases:

>100_bases
GGCGCACAATGCTGCGGATTGCGCACTCCCCGGTTTCCCAATCGTGCGACAGGTTGTAGAACCCGACACGAAACCCGCAC
CCGCCAACCGGAGACGCGCC

Downstream 100 bases:

>100_bases
CGTCGTTGCGTGCGATGATGCTGGCACTGGGGCTTTGCATGGCTCTGCCCGTCCCTGCTGTCGCTCAGGATCCGGGCGAT
GCGGCCCTCGAGGCGGCGGT

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-independent PGAM; Phosphoglyceromutase; iPGM

Number of amino acids: Translated: 506; Mature: 505

Protein sequence:

>506_residues
MTTPKPVVLCILDGWGSAEPGPANAPYLAKTPTLDAIMQSCPTARLVTHGPDVGLPSGQMGNSEVGHTNIGAGRVVAMDL
GQIDLAIEDGSFYDNDALQAFIAKLKETGGAAHLMGLVSDGGVHGHVTHILAAIKAIRDAGVPVWLHAITDGRDVAPKSA
LTYLDQLEAGMAPGAQIATVTGRYFAMDRDNRWERVSEAYDAMVKGAGQFTAATARDAVENAYGRDELDEFVKATVVEGF
DGIKEGDGFFCLNFRADRAREILRAIGEPGFAEFDTGPRPALAALLGMVEYSEGHNAYMTTAYPKRAIVNTLGEWVAKQG
KRQFRLAETEKYPHVTFFLNGGKETPEVGEDRFMPKSPKVATYDLQPEMSAPEVTAKFVEAIRAGYDLIVTNYANPDMVG
HTGDLDAAIKACEAVDQGLGEVVAALKDAGGAMIVTADHGNCELMVDPETGGAHTAHTTNLVPVALVGGPEGTALKDGRL
ADLAPTLLALMGLDQPEEMTGESLLV

Sequences:

>Translated_506_residues
MTTPKPVVLCILDGWGSAEPGPANAPYLAKTPTLDAIMQSCPTARLVTHGPDVGLPSGQMGNSEVGHTNIGAGRVVAMDL
GQIDLAIEDGSFYDNDALQAFIAKLKETGGAAHLMGLVSDGGVHGHVTHILAAIKAIRDAGVPVWLHAITDGRDVAPKSA
LTYLDQLEAGMAPGAQIATVTGRYFAMDRDNRWERVSEAYDAMVKGAGQFTAATARDAVENAYGRDELDEFVKATVVEGF
DGIKEGDGFFCLNFRADRAREILRAIGEPGFAEFDTGPRPALAALLGMVEYSEGHNAYMTTAYPKRAIVNTLGEWVAKQG
KRQFRLAETEKYPHVTFFLNGGKETPEVGEDRFMPKSPKVATYDLQPEMSAPEVTAKFVEAIRAGYDLIVTNYANPDMVG
HTGDLDAAIKACEAVDQGLGEVVAALKDAGGAMIVTADHGNCELMVDPETGGAHTAHTTNLVPVALVGGPEGTALKDGRL
ADLAPTLLALMGLDQPEEMTGESLLV
>Mature_505_residues
TTPKPVVLCILDGWGSAEPGPANAPYLAKTPTLDAIMQSCPTARLVTHGPDVGLPSGQMGNSEVGHTNIGAGRVVAMDLG
QIDLAIEDGSFYDNDALQAFIAKLKETGGAAHLMGLVSDGGVHGHVTHILAAIKAIRDAGVPVWLHAITDGRDVAPKSAL
TYLDQLEAGMAPGAQIATVTGRYFAMDRDNRWERVSEAYDAMVKGAGQFTAATARDAVENAYGRDELDEFVKATVVEGFD
GIKEGDGFFCLNFRADRAREILRAIGEPGFAEFDTGPRPALAALLGMVEYSEGHNAYMTTAYPKRAIVNTLGEWVAKQGK
RQFRLAETEKYPHVTFFLNGGKETPEVGEDRFMPKSPKVATYDLQPEMSAPEVTAKFVEAIRAGYDLIVTNYANPDMVGH
TGDLDAAIKACEAVDQGLGEVVAALKDAGGAMIVTADHGNCELMVDPETGGAHTAHTTNLVPVALVGGPEGTALKDGRLA
DLAPTLLALMGLDQPEEMTGESLLV

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0696

COG function: function code G; Phosphoglyceromutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BPG-independent phosphoglycerate mutase family

Homologues:

Organism=Escherichia coli, GI1790041, Length=516, Percent_Identity=48.4496124031008, Blast_Score=479, Evalue=1e-136,
Organism=Caenorhabditis elegans, GI32564249, Length=513, Percent_Identity=45.6140350877193, Blast_Score=411, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17507741, Length=518, Percent_Identity=45.1737451737452, Blast_Score=411, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPMI_SILST (Q1GCX7)

Other databases:

- EMBL:   CP000377
- RefSeq:   YP_614751.1
- ProteinModelPortal:   Q1GCX7
- SMR:   Q1GCX7
- STRING:   Q1GCX7
- GeneID:   4077629
- GenomeReviews:   CP000377_GR
- KEGG:   sit:TM1040_2757
- NMPDR:   fig|292414.1.peg.1664
- eggNOG:   COG0696
- HOGENOM:   HBG613255
- OMA:   DHGNAEL
- PhylomeDB:   Q1GCX7
- ProtClustDB:   PRK05434
- BioCyc:   SSP292414:TM1040_2757-MONOMER
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_01038
- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR011258
- InterPro:   IPR006124
- InterPro:   IPR005995
- Gene3D:   G3DSA:3.40.720.10
- Gene3D:   G3DSA:3.40.1450.10
- PIRSF:   PIRSF001492
- TIGRFAMs:   TIGR01307

Pfam domain/function: PF06415 iPGM_N; PF01676 Metalloenzyme; SSF53649 Alkaline_phosphatase_core; SSF64158 BPG-indep_PGM_N

EC number: =5.4.2.1

Molecular weight: Translated: 53564; Mature: 53433

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: ACT_SITE 63-63

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPKPVVLCILDGWGSAEPGPANAPYLAKTPTLDAIMQSCPTARLVTHGPDVGLPSGQM
CCCCCCEEEEEEECCCCCCCCCCCCCCEECCCCHHHHHHHCCCCEEEECCCCCCCCCCCC
GNSEVGHTNIGAGRVVAMDLGQIDLAIEDGSFYDNDALQAFIAKLKETGGAAHLMGLVSD
CCCCCCCCCCCCCEEEEEECCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEECCC
GGVHGHVTHILAAIKAIRDAGVPVWLHAITDGRDVAPKSALTYLDQLEAGMAPGAQIATV
CCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEEE
TGRYFAMDRDNRWERVSEAYDAMVKGAGQFTAATARDAVENAYGRDELDEFVKATVVEGF
ECEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
DGIKEGDGFFCLNFRADRAREILRAIGEPGFAEFDTGPRPALAALLGMVEYSEGHNAYMT
CCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEE
TAYPKRAIVNTLGEWVAKQGKRQFRLAETEKYPHVTFFLNGGKETPEVGEDRFMPKSPKV
CCCCHHHHHHHHHHHHHHCCCHHEEEHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCE
ATYDLQPEMSAPEVTAKFVEAIRAGYDLIVTNYANPDMVGHTGDLDAAIKACEAVDQGLG
EEEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
EVVAALKDAGGAMIVTADHGNCELMVDPETGGAHTAHTTNLVPVALVGGPEGTALKDGRL
HHHHHHHCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCH
ADLAPTLLALMGLDQPEEMTGESLLV
HHHHHHHHHHHCCCCCHHHCCCCCCC
>Mature Secondary Structure 
TTPKPVVLCILDGWGSAEPGPANAPYLAKTPTLDAIMQSCPTARLVTHGPDVGLPSGQM
CCCCCEEEEEEECCCCCCCCCCCCCCEECCCCHHHHHHHCCCCEEEECCCCCCCCCCCC
GNSEVGHTNIGAGRVVAMDLGQIDLAIEDGSFYDNDALQAFIAKLKETGGAAHLMGLVSD
CCCCCCCCCCCCCEEEEEECCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEECCC
GGVHGHVTHILAAIKAIRDAGVPVWLHAITDGRDVAPKSALTYLDQLEAGMAPGAQIATV
CCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEEE
TGRYFAMDRDNRWERVSEAYDAMVKGAGQFTAATARDAVENAYGRDELDEFVKATVVEGF
ECEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
DGIKEGDGFFCLNFRADRAREILRAIGEPGFAEFDTGPRPALAALLGMVEYSEGHNAYMT
CCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEE
TAYPKRAIVNTLGEWVAKQGKRQFRLAETEKYPHVTFFLNGGKETPEVGEDRFMPKSPKV
CCCCHHHHHHHHHHHHHHCCCHHEEEHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCE
ATYDLQPEMSAPEVTAKFVEAIRAGYDLIVTNYANPDMVGHTGDLDAAIKACEAVDQGLG
EEEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
EVVAALKDAGGAMIVTADHGNCELMVDPETGGAHTAHTTNLVPVALVGGPEGTALKDGRL
HHHHHHHCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCH
ADLAPTLLALMGLDQPEEMTGESLLV
HHHHHHHHHHHCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA