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The map label for this gene is acpS

Identifier: 99082401

GI number: 99082401

Start: 2704558

End: 2704986

Strand: Reverse

Name: acpS

Synonym: TM1040_2561

Alternate gene names: 99082401

Gene position: 2704986-2704558 (Counterclockwise)

Preceding gene: 99082402

Following gene: 99082400

Centisome position: 84.51

GC content: 60.84

Gene sequence:

>429_bases
ATGATTCTCGGCATCGGTACGGATCTGGCAAATATCGAACGCATCCAAGGCGTGTTGGATCGGTTTGGCGATCGGTTTCG
CAATCGGGTTTTTACCGATGTCGAACAGGCGAAATCCGAGCGTCGCCTCGATGTGGCAGGCACCTACGCAAAGCGCTGGG
CGGCCAAGGAGGCCTGCTCCAAGGCGCTTGGGACCGGCCTGCGCATGGGGATCGCGTGGAAGGACATGTCGGTTTCCAAC
CTCTCGACCGGGCAGCCGGTGATGCACGTAACCGGTTGGGCCAAGGCGCGGCTGGATGAATTGACGCCGCCGGGGCATGA
GGCGGTGATCCATGTGACCCTCACCGATGATCACCCCTGGGCACAGGCGGTCGTGATGATCGAAGCACGTCCGATCTTGC
CCGACGTCCAGACAGCACAGACGACATAA

Upstream 100 bases:

>100_bases
TCTCCTTTCTGCTGGTCCGGTTCTTCTTGGCGACCGGCGCAAAGTCCATGCTGCGGGCACAGAAACGCCCATGAGCAGAG
CGATCTGAGGGAAAGACCAA

Downstream 100 bases:

>100_bases
GCCTTCTGAGCACGGCCTCCCGGCTGCAGGGAACAGCGTGCCTGCATCGCGCCACAAACGCGCGCTCTGATCGCCACCGC
TTGACTTGCGGCGGACAGCC

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MILGIGTDLANIERIQGVLDRFGDRFRNRVFTDVEQAKSERRLDVAGTYAKRWAAKEACSKALGTGLRMGIAWKDMSVSN
LSTGQPVMHVTGWAKARLDELTPPGHEAVIHVTLTDDHPWAQAVVMIEARPILPDVQTAQTT

Sequences:

>Translated_142_residues
MILGIGTDLANIERIQGVLDRFGDRFRNRVFTDVEQAKSERRLDVAGTYAKRWAAKEACSKALGTGLRMGIAWKDMSVSN
LSTGQPVMHVTGWAKARLDELTPPGHEAVIHVTLTDDHPWAQAVVMIEARPILPDVQTAQTT
>Mature_142_residues
MILGIGTDLANIERIQGVLDRFGDRFRNRVFTDVEQAKSERRLDVAGTYAKRWAAKEACSKALGTGLRMGIAWKDMSVSN
LSTGQPVMHVTGWAKARLDELTPPGHEAVIHVTLTDDHPWAQAVVMIEARPILPDVQTAQTT

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=128, Percent_Identity=40.625, Blast_Score=84, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_SILST (Q1GDH3)

Other databases:

- EMBL:   CP000377
- RefSeq:   YP_614555.1
- ProteinModelPortal:   Q1GDH3
- SMR:   Q1GDH3
- STRING:   Q1GDH3
- GeneID:   4076692
- GenomeReviews:   CP000377_GR
- KEGG:   sit:TM1040_2561
- NMPDR:   fig|292414.1.peg.723
- eggNOG:   COG0736
- HOGENOM:   HBG734479
- OMA:   AYAKRWA
- PhylomeDB:   Q1GDH3
- ProtClustDB:   PRK00070
- BioCyc:   SSP292414:TM1040_2561-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 15664; Mature: 15664

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILGIGTDLANIERIQGVLDRFGDRFRNRVFTDVEQAKSERRLDVAGTYAKRWAAKEACS
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
KALGTGLRMGIAWKDMSVSNLSTGQPVMHVTGWAKARLDELTPPGHEAVIHVTLTDDHPW
HHHCCCCEECEEECCCCCCCCCCCCCEEEECCHHHHHHHHCCCCCCCEEEEEEECCCCCC
AQAVVMIEARPILPDVQTAQTT
CEEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MILGIGTDLANIERIQGVLDRFGDRFRNRVFTDVEQAKSERRLDVAGTYAKRWAAKEACS
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
KALGTGLRMGIAWKDMSVSNLSTGQPVMHVTGWAKARLDELTPPGHEAVIHVTLTDDHPW
HHHCCCCEECEEECCCCCCCCCCCCCEEEECCHHHHHHHHCCCCCCCEEEEEEECCCCCC
AQAVVMIEARPILPDVQTAQTT
CEEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA