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The map label for this gene is cobL [H]

Identifier: 99082056

GI number: 99082056

Start: 2328500

End: 2329525

Strand: Direct

Name: cobL [H]

Synonym: TM1040_2216

Alternate gene names: 99082056

Gene position: 2328500-2329525 (Clockwise)

Preceding gene: 99082054

Following gene: 99082057

Centisome position: 72.74

GC content: 66.37

Gene sequence:

>1026_bases
GTGCCCTTTTCCACCGCGCCGGTGCTGGCTGCGCGCGGGCGCCCCACGGTGGTGCTCGCCTCTGGCGATCCGTTCTGGCA
CGGCGCCGGGGGCAGCCTTCTGCGTGATTTAGAGCGGTCTGAATGGGTCTCGCACCCGGCGCCCTCCTGTTTTGCACTTG
CGGCAAATGCCCTCGGCTGGAAGCTTGAAGACACGCTATGCCTTGGCCTTCATGCAGCGCCCTTTGCGCGCCTGCGGCCG
CTTTTGGAGGCGGGCCAGCGGGTCCTTTGTACCCTGCGGGATGGTGCCGCCGCTGCGGAACTTGCGGCCTATCTTTGCGA
AATTGGGTTTGGCGCCAGCTCCCTCACCGCTCTGGAGCGCCTTGGCGGACCACACGCTCGAATCCGGCACACCACCGCCG
CGGGGTTTGACCTTCCTGAGGTCGACGCGCCCGTGCTGGCCGCAATCGACGCCAGAGGTCAGGGACTGCCGCAGGCCTCC
GGCCTTGAGGATACGCTCTTTGCCAGCGACGGGCAGATCACCAAACGCCCTGTCCGGGCGCTGACCCTCTCGGCGCTTGC
GCCGCGCAGAGGCGCGCATCTGTGGGACATTGGCGGCGGCTCTGGCTCGGTATCGGTGGAATGGTGCCTGGCGGCCCAAG
GGGCCACGGCAACCACCTTTGAAGCGCGCGCAGACAGGCTCGAAAATATTCGCCGCAATCGGCGCGATTTTGGCCTTGAG
CATCGCCTGACCCCGGTAGAAGGCCGTGCGCCCGACGTCCTGAAGAACCAACCTCTGCCCGATTGTGTCTTTATCGGGGG
CGGCGGCTCGGAGGCGTTACTGAATTACCTCTGGCAGATCCTGCCGCAAGGCACGCGCCTCGTCGCCAATGGGGTCACGC
TGGAAACGGAGACTCTCCTGATGCAGGCCCATGCGCGCCTTGGAGGCCATTTGCTGAAGGTGGAGATCGCCGAAGCGGGC
CCCTTGGGCACACTGCGCGGATGGGAGCGCGCGCGCCCCGTGATCCAATGGAGCGTGACCCGATGA

Upstream 100 bases:

>100_bases
GGATGCAAGCCGATCCGCACTCTCTAGGGCGGAAATCATTATCGGAGGGCCCCGCCATCTGGATCTGGTAGGCGCAGGCA
CACGCGGCCAATGCTGGCCT

Downstream 100 bases:

>100_bases
TCGTTGCAGGCTTTGGCTTTTCAAACCGCGCCTCTGAGGCCAGCTTTGCCGAGGCTTTTGCCGCATTGGACAGGCGCCCG
GATTGGGTGGCCGTTTTGCG

Product: precorrin-6y C5,15-methyltransferase, subunit CbiE

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MPFSTAPVLAARGRPTVVLASGDPFWHGAGGSLLRDLERSEWVSHPAPSCFALAANALGWKLEDTLCLGLHAAPFARLRP
LLEAGQRVLCTLRDGAAAAELAAYLCEIGFGASSLTALERLGGPHARIRHTTAAGFDLPEVDAPVLAAIDARGQGLPQAS
GLEDTLFASDGQITKRPVRALTLSALAPRRGAHLWDIGGGSGSVSVEWCLAAQGATATTFEARADRLENIRRNRRDFGLE
HRLTPVEGRAPDVLKNQPLPDCVFIGGGGSEALLNYLWQILPQGTRLVANGVTLETETLLMQAHARLGGHLLKVEIAEAG
PLGTLRGWERARPVIQWSVTR

Sequences:

>Translated_341_residues
MPFSTAPVLAARGRPTVVLASGDPFWHGAGGSLLRDLERSEWVSHPAPSCFALAANALGWKLEDTLCLGLHAAPFARLRP
LLEAGQRVLCTLRDGAAAAELAAYLCEIGFGASSLTALERLGGPHARIRHTTAAGFDLPEVDAPVLAAIDARGQGLPQAS
GLEDTLFASDGQITKRPVRALTLSALAPRRGAHLWDIGGGSGSVSVEWCLAAQGATATTFEARADRLENIRRNRRDFGLE
HRLTPVEGRAPDVLKNQPLPDCVFIGGGGSEALLNYLWQILPQGTRLVANGVTLETETLLMQAHARLGGHLLKVEIAEAG
PLGTLRGWERARPVIQWSVTR
>Mature_340_residues
PFSTAPVLAARGRPTVVLASGDPFWHGAGGSLLRDLERSEWVSHPAPSCFALAANALGWKLEDTLCLGLHAAPFARLRPL
LEAGQRVLCTLRDGAAAAELAAYLCEIGFGASSLTALERLGGPHARIRHTTAAGFDLPEVDAPVLAAIDARGQGLPQASG
LEDTLFASDGQITKRPVRALTLSALAPRRGAHLWDIGGGSGSVSVEWCLAAQGATATTFEARADRLENIRRNRRDFGLEH
RLTPVEGRAPDVLKNQPLPDCVFIGGGGSEALLNYLWQILPQGTRLVANGVTLETETLLMQAHARLGGHLLKVEIAEAGP
LGTLRGWERARPVIQWSVTR

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2242

COG function: function code H; Precorrin-6B methylase 2

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 36289; Mature: 36158

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFSTAPVLAARGRPTVVLASGDPFWHGAGGSLLRDLERSEWVSHPAPSCFALAANALGW
CCCCCCCEEEECCCCEEEEECCCCCEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
KLEDTLCLGLHAAPFARLRPLLEAGQRVLCTLRDGAAAAELAAYLCEIGFGASSLTALER
EECCEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHH
LGGPHARIRHTTAAGFDLPEVDAPVLAAIDARGQGLPQASGLEDTLFASDGQITKRPVRA
CCCCCCEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHEECCCCCCCHHHHHH
LTLSALAPRRGAHLWDIGGGSGSVSVEWCLAAQGATATTFEARADRLENIRRNRRDFGLE
HHHHHHCCCCCCEEEEECCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCHH
HRLTPVEGRAPDVLKNQPLPDCVFIGGGGSEALLNYLWQILPQGTRLVANGVTLETETLL
HCCCCCCCCCCHHHCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEECCCEEEHHHHH
MQAHARLGGHLLKVEIAEAGPLGTLRGWERARPVIQWSVTR
HHHHHHHCCEEEEEEEECCCCCCCCCCHHHCCCEEEEEECC
>Mature Secondary Structure 
PFSTAPVLAARGRPTVVLASGDPFWHGAGGSLLRDLERSEWVSHPAPSCFALAANALGW
CCCCCCEEEECCCCEEEEECCCCCEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
KLEDTLCLGLHAAPFARLRPLLEAGQRVLCTLRDGAAAAELAAYLCEIGFGASSLTALER
EECCEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHH
LGGPHARIRHTTAAGFDLPEVDAPVLAAIDARGQGLPQASGLEDTLFASDGQITKRPVRA
CCCCCCEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHEECCCCCCCHHHHHH
LTLSALAPRRGAHLWDIGGGSGSVSVEWCLAAQGATATTFEARADRLENIRRNRRDFGLE
HHHHHHCCCCCCEEEEECCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCHH
HRLTPVEGRAPDVLKNQPLPDCVFIGGGGSEALLNYLWQILPQGTRLVANGVTLETETLL
HCCCCCCCCCCHHHCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEECCCEEEHHHHH
MQAHARLGGHLLKVEIAEAGPLGTLRGWERARPVIQWSVTR
HHHHHHHCCEEEEEEEECCCCCCCCCCHHHCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732195 [H]