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The map label for this gene is nrdR [H]

Identifier: 99081976

GI number: 99081976

Start: 2242735

End: 2243202

Strand: Reverse

Name: nrdR [H]

Synonym: TM1040_2136

Alternate gene names: 99081976

Gene position: 2243202-2242735 (Counterclockwise)

Preceding gene: 99081977

Following gene: 99081975

Centisome position: 70.08

GC content: 58.76

Gene sequence:

>468_bases
ATGCGTTGCCCATTTTGCGGAAATGTCGATACGCAAGTAAAGGACTCGCGTCCGGCAGAGGATCACGTTTCGATCCGCCG
ACGCCGGTTTTGCCCTGCCTGCGGTGGCCGTTTTACCACGTATGAACGGGTGCAGCTGCGCGACCTCGTGGTGATCAAGA
CCAACGGCAAGCGCGAGGATTTCGACCGCGACAAGCTAGAACGCTCCATTCGCATCTCGATGCAGAAACGCCCGGTGGAC
CCGGAACGGATCGATCAAATGATCTCGGGCATCGTGCGCCGTCTGGAGAGCATGGGCGAGACGGATATTCCTTCCAAAAA
GATCGGCGAAATCGTGATGGAGGCTCTGGCCCGCATCGACACCGTCGCCTATGTTCGCTTCGCAAGCGTCTACAAGAATT
TTCAGGCGGCCGACGACTTTGAGGATTTTGTGCACGAGCTGCGCCCCCCTGCGCCGCCCGAGAGCTGA

Upstream 100 bases:

>100_bases
ATTTCCCCTCTACCCAAATCCTAGCTGGTCCCCTATAGTTGTGGATAAATGCGCAAACCTGCGCACAAGAACAATTTATC
GCGAGGGGAGGGGCCAGAGG

Downstream 100 bases:

>100_bases
GATCCCGGCCTCGCTGCCTGCGCAGAGTCTGGCAAAAGGTCTGATCCATTGAGCAAAAGCGACGACCACCGTTTTATGGG
GCTCGCCCTGTCGCTCGGGC

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MRCPFCGNVDTQVKDSRPAEDHVSIRRRRFCPACGGRFTTYERVQLRDLVVIKTNGKREDFDRDKLERSIRISMQKRPVD
PERIDQMISGIVRRLESMGETDIPSKKIGEIVMEALARIDTVAYVRFASVYKNFQAADDFEDFVHELRPPAPPES

Sequences:

>Translated_155_residues
MRCPFCGNVDTQVKDSRPAEDHVSIRRRRFCPACGGRFTTYERVQLRDLVVIKTNGKREDFDRDKLERSIRISMQKRPVD
PERIDQMISGIVRRLESMGETDIPSKKIGEIVMEALARIDTVAYVRFASVYKNFQAADDFEDFVHELRPPAPPES
>Mature_155_residues
MRCPFCGNVDTQVKDSRPAEDHVSIRRRRFCPACGGRFTTYERVQLRDLVVIKTNGKREDFDRDKLERSIRISMQKRPVD
PERIDQMISGIVRRLESMGETDIPSKKIGEIVMEALARIDTVAYVRFASVYKNFQAADDFEDFVHELRPPAPPES

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes [H]

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain [H]

Homologues:

Organism=Escherichia coli, GI1786615, Length=147, Percent_Identity=43.5374149659864, Blast_Score=126, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003796 [H]

Pfam domain/function: PF03477 ATP-cone [H]

EC number: NA

Molecular weight: Translated: 17934; Mature: 17934

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPFCGNVDTQVKDSRPAEDHVSIRRRRFCPACGGRFTTYERVQLRDLVVIKTNGKRED
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHEEEEEEEECCCCCCC
FDRDKLERSIRISMQKRPVDPERIDQMISGIVRRLESMGETDIPSKKIGEIVMEALARID
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
TVAYVRFASVYKNFQAADDFEDFVHELRPPAPPES
HHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRCPFCGNVDTQVKDSRPAEDHVSIRRRRFCPACGGRFTTYERVQLRDLVVIKTNGKRED
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHEEEEEEEECCCCCCC
FDRDKLERSIRISMQKRPVDPERIDQMISGIVRRLESMGETDIPSKKIGEIVMEALARID
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
TVAYVRFASVYKNFQAADDFEDFVHELRPPAPPES
HHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA