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The map label for this gene is atpH [H]

Identifier: 99081929

GI number: 99081929

Start: 2193128

End: 2193781

Strand: Reverse

Name: atpH [H]

Synonym: TM1040_2089

Alternate gene names: 99081929

Gene position: 2193781-2193128 (Counterclockwise)

Preceding gene: 99081930

Following gene: 99081928

Centisome position: 68.54

GC content: 59.79

Gene sequence:

>654_bases
ATGCCCGGCCAAAATCGGGCGACCTCACGCCCCCGGATGCTACCTGCCAGGACGCATATAAACCGGGGCCAAAATAATAT
CGGAAGGGTGGACGTGTCCGAACCAGCTTCGATTTCCGCAGGCATTGCCGACCGCTATGCCACAGCGATCTTCGAGATCG
CTGCCGAGAGCAATGCTCTCGACAACCTCGAGACTAGCATCAACGATCTGGCAGCCTCCCTGGCTGACAGCGAAGACCTG
CGTACTCTCATCACCTCACCGCTGGTGTCGCGTGAGGAACAGGCCGCTGCGATCTCTGCCGTAGCGGACAAGATGGGGCT
TGTAGATGTACTGCGCAACTCCCTCGCGCTGATGGCGGCCAAACGCCGCCTGTTTGTGGTGCCCGCCCTGATCGACGCGC
TGCGCGCCCGTATCGCAGAAGCCCGTGGCGAAGTGACCGCCGAGGTCGTCTCCGCCAAGGCGCTGACCAAGACGCAGAGC
GAAAAACTGGCCAAAACCCTCGCCGAGCGCGTGGGCAAGAAGGTCACCATCAATGCCACCGTCGATGCAAGCATCATCGG
CGGTCTCGTCGTTAAAGTGGGCTCGAAGATGATCGACAGTTCGATCCGCTCCAAGCTCAACTCCCTACAGAATGCAATGA
AAGAGGTCGGATAA

Upstream 100 bases:

>100_bases
TTTTGTTAAGTCATTGAAAACGTGTGACTTCGGTTTTCGCAGCTTCGGACAGAGGGAGTTGCTAGGTCGCAAAGGCTCTG
CTACATCCACGCTGATTTCG

Downstream 100 bases:

>100_bases
ATGGGTATCCAAGCAGCGGAAATTTCCGCGATCCTTAAAGACCAGATCAAGAATTTTGGTCAAGAAGCCGAAGTGGCCGA
GATTGGTCGCGTGCTCTCCG

Product: ATP synthase F1, delta subunit

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta [H]

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MPGQNRATSRPRMLPARTHINRGQNNIGRVDVSEPASISAGIADRYATAIFEIAAESNALDNLETSINDLAASLADSEDL
RTLITSPLVSREEQAAAISAVADKMGLVDVLRNSLALMAAKRRLFVVPALIDALRARIAEARGEVTAEVVSAKALTKTQS
EKLAKTLAERVGKKVTINATVDASIIGGLVVKVGSKMIDSSIRSKLNSLQNAMKEVG

Sequences:

>Translated_217_residues
MPGQNRATSRPRMLPARTHINRGQNNIGRVDVSEPASISAGIADRYATAIFEIAAESNALDNLETSINDLAASLADSEDL
RTLITSPLVSREEQAAAISAVADKMGLVDVLRNSLALMAAKRRLFVVPALIDALRARIAEARGEVTAEVVSAKALTKTQS
EKLAKTLAERVGKKVTINATVDASIIGGLVVKVGSKMIDSSIRSKLNSLQNAMKEVG
>Mature_216_residues
PGQNRATSRPRMLPARTHINRGQNNIGRVDVSEPASISAGIADRYATAIFEIAAESNALDNLETSINDLAASLADSEDLR
TLITSPLVSREEQAAAISAVADKMGLVDVLRNSLALMAAKRRLFVVPALIDALRARIAEARGEVTAEVVSAKALTKTQSE
KLAKTLAERVGKKVTINATVDASIIGGLVVKVGSKMIDSSIRSKLNSLQNAMKEVG

Specific function: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction [H]

COG id: COG0712

COG function: function code C; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase delta chain family [H]

Homologues:

Organism=Homo sapiens, GI4502303, Length=178, Percent_Identity=28.0898876404494, Blast_Score=78, Evalue=7e-15,
Organism=Escherichia coli, GI1790173, Length=176, Percent_Identity=26.7045454545455, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71984710, Length=175, Percent_Identity=29.1428571428571, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71984717, Length=175, Percent_Identity=29.1428571428571, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24647054, Length=169, Percent_Identity=34.9112426035503, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24647056, Length=114, Percent_Identity=36.8421052631579, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000711
- InterPro:   IPR020781 [H]

Pfam domain/function: PF00213 OSCP [H]

EC number: 3.6.3.14

Molecular weight: Translated: 22987; Mature: 22856

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: PS00389 ATPASE_DELTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGQNRATSRPRMLPARTHINRGQNNIGRVDVSEPASISAGIADRYATAIFEIAAESNAL
CCCCCCCCCCCCCCCHHHHHCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHCCHH
DNLETSINDLAASLADSEDLRTLITSPLVSREEQAAAISAVADKMGLVDVLRNSLALMAA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRRLFVVPALIDALRARIAEARGEVTAEVVSAKALTKTQSEKLAKTLAERVGKKVTINAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
VDASIIGGLVVKVGSKMIDSSIRSKLNSLQNAMKEVG
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PGQNRATSRPRMLPARTHINRGQNNIGRVDVSEPASISAGIADRYATAIFEIAAESNAL
CCCCCCCCCCCCCCHHHHHCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHCCHH
DNLETSINDLAASLADSEDLRTLITSPLVSREEQAAAISAVADKMGLVDVLRNSLALMAA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRRLFVVPALIDALRARIAEARGEVTAEVVSAKALTKTQSEKLAKTLAERVGKKVTINAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
VDASIIGGLVVKVGSKMIDSSIRSKLNSLQNAMKEVG
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA