Click here to switch to the map view.

The map label for this gene is hflK [H]

Identifier: 99081796

GI number: 99081796

Start: 2060073

End: 2061236

Strand: Reverse

Name: hflK [H]

Synonym: TM1040_1956

Alternate gene names: 99081796

Gene position: 2061236-2060073 (Counterclockwise)

Preceding gene: 99081797

Following gene: 99081795

Centisome position: 64.39

GC content: 62.2

Gene sequence:

>1164_bases
ATGGCTGGGAACAGTGGTGGCCCCTGGGGGGGCGGCGGTTCCTCCGGCGGCGGAGGCAACCGGGGAAACAACGGCGGCAA
CAACGGAGGCGGCGGCGGTGGCCGGCGTCCTGATGATGGCCAGATCCCCGAGATCGACGAGCTGGTGAAGAAAGGCCAAG
AGCAGCTGCGCGTCCTGATGGGCGGCCGTGGCGGCAATGGCGGCAACGGGCAGGGACCGCAGGGCGGTGGCTCTGGCGGC
AGCCCCTTGTTCACCAAAGGCGGGCTGATGCTCGGCGCGGTCGCTGCGGTTTTCCTCTGGGGTTACAACAGCTTCTACAC
CGTAAAGACCGAAGAGAAATCCGTCGAGCTGTTCCTTGGCGAGTTCTCCGCGGTGGGCAATCCGGGTCTGAACTTCGCAC
CCTGGCCTGTGGTCACCTATGAGGTAGTCCCGGTCAGCGTGGAACAGACCGAGAGCATTGGCGCAGGCGCGCGCGGCTCT
GATGCGGGTCTGATGCTGACGGGCGATGAGAACATCATCGACGTCGACTTCCAAGTGGTCTGGAACATCAACGAGCCCGA
CAAATTCCTCTTTAACTTGCGCGATCCAAAGGCGACCATTCAGGCCGTGTCTGAATCCGCGATGCGAGAGATCATTGCAC
AATCGCAGCTGGCGCCGATCTTGAACCGTGACCGCGGTCTCATTTCGCAGCGCCTCGAAGAGCTGATCCAGTCCACCCTC
GACAGCTATGACGCAGGCGTGAACATCGTCCGGGTCAACTTTGACGGGGCCGATCCGCCTGAACCGGTAAAAGACGCCTT
CCGCGAAGTTCAGTCTGCCGGTCAGGAACGAGACCGTCTGGAAAAGCAGGCTGACGCTTATGCCAACCGCAAACTCGCGG
CGGCGCGTGGTCAGGCCGCACAGACACTCGAAGAAGCAGAAGCCTACCGCGCGCAGGTCGTGAACCAGGCGCAGGGTGAG
GCCTCGCGCTTTACGGCCGTTCTGTCGGAATACGAGAAGGCACCGGAAGTGACGCGCAAGCGTCTCTATCTGGAAACCAT
GGAGGACGTGCTGAGCCGCGTGGACAAGATCATCCTTGATGACAACGCCGGGAGCGAAGGCGGACAGGGCATCGTGCCGT
ATCTGCCGCTCAATGAAATCCGTCGTTCCGGAGGGAGCAACTGA

Upstream 100 bases:

>100_bases
CAGAGTTTGGTCGCGACGCTGATCTTGAATTTCAGCGCCGTGACCACAGGTTACAGGGCAATATCCGCTGTATCAGCGGG
GAGAGATGGATAGGAGACTT

Downstream 100 bases:

>100_bases
TGAATCGCTCTGTTATTCTTCTCGTCCTTCTGGGCGCTATTGTCGTGGGCGCACTGTCCTCGCTCTTTATCGTGGACGAG
CGTGAGAAGGCGCTGGTTCT

Product: HflK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MAGNSGGPWGGGGSSGGGGNRGNNGGNNGGGGGGRRPDDGQIPEIDELVKKGQEQLRVLMGGRGGNGGNGQGPQGGGSGG
SPLFTKGGLMLGAVAAVFLWGYNSFYTVKTEEKSVELFLGEFSAVGNPGLNFAPWPVVTYEVVPVSVEQTESIGAGARGS
DAGLMLTGDENIIDVDFQVVWNINEPDKFLFNLRDPKATIQAVSESAMREIIAQSQLAPILNRDRGLISQRLEELIQSTL
DSYDAGVNIVRVNFDGADPPEPVKDAFREVQSAGQERDRLEKQADAYANRKLAAARGQAAQTLEEAEAYRAQVVNQAQGE
ASRFTAVLSEYEKAPEVTRKRLYLETMEDVLSRVDKIILDDNAGSEGGQGIVPYLPLNEIRRSGGSN

Sequences:

>Translated_387_residues
MAGNSGGPWGGGGSSGGGGNRGNNGGNNGGGGGGRRPDDGQIPEIDELVKKGQEQLRVLMGGRGGNGGNGQGPQGGGSGG
SPLFTKGGLMLGAVAAVFLWGYNSFYTVKTEEKSVELFLGEFSAVGNPGLNFAPWPVVTYEVVPVSVEQTESIGAGARGS
DAGLMLTGDENIIDVDFQVVWNINEPDKFLFNLRDPKATIQAVSESAMREIIAQSQLAPILNRDRGLISQRLEELIQSTL
DSYDAGVNIVRVNFDGADPPEPVKDAFREVQSAGQERDRLEKQADAYANRKLAAARGQAAQTLEEAEAYRAQVVNQAQGE
ASRFTAVLSEYEKAPEVTRKRLYLETMEDVLSRVDKIILDDNAGSEGGQGIVPYLPLNEIRRSGGSN
>Mature_386_residues
AGNSGGPWGGGGSSGGGGNRGNNGGNNGGGGGGRRPDDGQIPEIDELVKKGQEQLRVLMGGRGGNGGNGQGPQGGGSGGS
PLFTKGGLMLGAVAAVFLWGYNSFYTVKTEEKSVELFLGEFSAVGNPGLNFAPWPVVTYEVVPVSVEQTESIGAGARGSD
AGLMLTGDENIIDVDFQVVWNINEPDKFLFNLRDPKATIQAVSESAMREIIAQSQLAPILNRDRGLISQRLEELIQSTLD
SYDAGVNIVRVNFDGADPPEPVKDAFREVQSAGQERDRLEKQADAYANRKLAAARGQAAQTLEEAEAYRAQVVNQAQGEA
SRFTAVLSEYEKAPEVTRKRLYLETMEDVLSRVDKIILDDNAGSEGGQGIVPYLPLNEIRRSGGSN

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=282, Percent_Identity=37.5886524822695, Blast_Score=197, Evalue=1e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 40962; Mature: 40831

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGNSGGPWGGGGSSGGGGNRGNNGGNNGGGGGGRRPDDGQIPEIDELVKKGQEQLRVLM
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
GGRGGNGGNGQGPQGGGSGGSPLFTKGGLMLGAVAAVFLWGYNSFYTVKTEEKSVELFLG
CCCCCCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHH
EFSAVGNPGLNFAPWPVVTYEVVPVSVEQTESIGAGARGSDAGLMLTGDENIIDVDFQVV
HHHHCCCCCCCCCCCCEEEEEEEEECHHHHHHCCCCCCCCCCCEEEECCCCEEEEEEEEE
WNINEPDKFLFNLRDPKATIQAVSESAMREIIAQSQLAPILNRDRGLISQRLEELIQSTL
EECCCCHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
DSYDAGVNIVRVNFDGADPPEPVKDAFREVQSAGQERDRLEKQADAYANRKLAAARGQAA
HHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHH
QTLEEAEAYRAQVVNQAQGEASRFTAVLSEYEKAPEVTRKRLYLETMEDVLSRVDKIILD
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
DNAGSEGGQGIVPYLPLNEIRRSGGSN
CCCCCCCCCCCCCCCCHHHHHHCCCCC
>Mature Secondary Structure 
AGNSGGPWGGGGSSGGGGNRGNNGGNNGGGGGGRRPDDGQIPEIDELVKKGQEQLRVLM
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
GGRGGNGGNGQGPQGGGSGGSPLFTKGGLMLGAVAAVFLWGYNSFYTVKTEEKSVELFLG
CCCCCCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHH
EFSAVGNPGLNFAPWPVVTYEVVPVSVEQTESIGAGARGSDAGLMLTGDENIIDVDFQVV
HHHHCCCCCCCCCCCCEEEEEEEEECHHHHHHCCCCCCCCCCCEEEECCCCEEEEEEEEE
WNINEPDKFLFNLRDPKATIQAVSESAMREIIAQSQLAPILNRDRGLISQRLEELIQSTL
EECCCCHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
DSYDAGVNIVRVNFDGADPPEPVKDAFREVQSAGQERDRLEKQADAYANRKLAAARGQAA
HHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHH
QTLEEAEAYRAQVVNQAQGEASRFTAVLSEYEKAPEVTRKRLYLETMEDVLSRVDKIILD
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
DNAGSEGGQGIVPYLPLNEIRRSGGSN
CCCCCCCCCCCCCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]