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The map label for this gene is hflC [H]

Identifier: 99081795

GI number: 99081795

Start: 2059189

End: 2060073

Strand: Reverse

Name: hflC [H]

Synonym: TM1040_1955

Alternate gene names: 99081795

Gene position: 2060073-2059189 (Counterclockwise)

Preceding gene: 99081796

Following gene: 99081793

Centisome position: 64.36

GC content: 61.36

Gene sequence:

>885_bases
ATGAATCGCTCTGTTATTCTTCTCGTCCTTCTGGGCGCTATTGTCGTGGGCGCACTGTCCTCGCTCTTTATCGTGGACGA
GCGTGAGAAGGCGCTGGTTCTGCGCTTTGGTCGTGTCGTGAACGTGCAGGAAGACCCCGGTCTGGCCTTCAAGCTTCCGT
TTGTGGACGAAGTCGTGAAATATGACGACCGTATCCTCAGCCTCGAAGTCGGGCCGCTCGAAGTGACGCCGCTGGATGAC
CGCCGCCTTGTCGTGGACGCTTTTGCACGCTACCGCATCACCGATGTACGTCGCTTCCGCGAAGCGGTCGGCGTTGGCAG
CGAAGCCGCTGCCGAGAGCCGTCTTGACAACATCATGCGCGACCAGACCCGCGAGGTTCTGGGTACTGTGAGCTCCAACG
ATATTCTGTCGTCGGACCGTGCGGCGCTGATGCTGCGGATCCGCAATGGCGCGATTGCGCAGGCGCGGGATCTGGGGCTC
GAGGTCATCGACGTGCGCCTGAAACGCACTGACCTGCCGCAAGCAAACCTTGAGGCGACCTTTGCCCGGATGCGCGCCGA
GCGTGAACGCGAAGCCGCTGACGAGATCGCCCGCGGTGAAGAAGCCGCGCAGCGTGTACGTGCGCAGGCGGATCGTACCG
AGGTGGAGCTTGTGTCTGAGGCGGAGCGAGAAGCCGAGGTTATCCGCGGTGAAGCGGATGCCGAGCGCAACAACATCTTT
GCAGAGGCCTATGGCGCGGACCCGGAGTTCTTTGAATTCTATCGTAGCCTCACCGCCTATGCGCGCGCGCTTCAGGGGGG
GAACTCCTCGCTGGTGCTGTCGCCGGACAATGAGTTCTTCAACTACCTGAAGTCTTCCGATGGTGCAGGCCGCGTGCAGC
AATAA

Upstream 100 bases:

>100_bases
ACAAGATCATCCTTGATGACAACGCCGGGAGCGAAGGCGGACAGGGCATCGTGCCGTATCTGCCGCTCAATGAAATCCGT
CGTTCCGGAGGGAGCAACTG

Downstream 100 bases:

>100_bases
GCTGCTTGGCATAAAGCATTGAAAAGGCCGCCCAGTTGGGCGGCCTTTTTTGTGTCTCTGGCGCACATCGTTCGGGCCTT
GGACGAAGGACCGTTGCCGA

Product: HflC protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MNRSVILLVLLGAIVVGALSSLFIVDEREKALVLRFGRVVNVQEDPGLAFKLPFVDEVVKYDDRILSLEVGPLEVTPLDD
RRLVVDAFARYRITDVRRFREAVGVGSEAAAESRLDNIMRDQTREVLGTVSSNDILSSDRAALMLRIRNGAIAQARDLGL
EVIDVRLKRTDLPQANLEATFARMRAEREREAADEIARGEEAAQRVRAQADRTEVELVSEAEREAEVIRGEADAERNNIF
AEAYGADPEFFEFYRSLTAYARALQGGNSSLVLSPDNEFFNYLKSSDGAGRVQQ

Sequences:

>Translated_294_residues
MNRSVILLVLLGAIVVGALSSLFIVDEREKALVLRFGRVVNVQEDPGLAFKLPFVDEVVKYDDRILSLEVGPLEVTPLDD
RRLVVDAFARYRITDVRRFREAVGVGSEAAAESRLDNIMRDQTREVLGTVSSNDILSSDRAALMLRIRNGAIAQARDLGL
EVIDVRLKRTDLPQANLEATFARMRAEREREAADEIARGEEAAQRVRAQADRTEVELVSEAEREAEVIRGEADAERNNIF
AEAYGADPEFFEFYRSLTAYARALQGGNSSLVLSPDNEFFNYLKSSDGAGRVQQ
>Mature_294_residues
MNRSVILLVLLGAIVVGALSSLFIVDEREKALVLRFGRVVNVQEDPGLAFKLPFVDEVVKYDDRILSLEVGPLEVTPLDD
RRLVVDAFARYRITDVRRFREAVGVGSEAAAESRLDNIMRDQTREVLGTVSSNDILSSDRAALMLRIRNGAIAQARDLGL
EVIDVRLKRTDLPQANLEATFARMRAEREREAADEIARGEEAAQRVRAQADRTEVELVSEAEREAEVIRGEADAERNNIF
AEAYGADPEFFEFYRSLTAYARALQGGNSSLVLSPDNEFFNYLKSSDGAGRVQQ

Specific function: HflC and HflK govern the stability of phage lambda cII protein and have been proposed to encode or regulate a cII- specific protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=316, Percent_Identity=33.5443037974684, Blast_Score=176, Evalue=1e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.-

Molecular weight: Translated: 32779; Mature: 32779

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRSVILLVLLGAIVVGALSSLFIVDEREKALVLRFGRVVNVQEDPGLAFKLPFVDEVVK
CCCHHHHHHHHHHHHHHHHHHHEEECCCCHHHHEECCCEEEEECCCCCEEECCHHHHHHH
YDDRILSLEVGPLEVTPLDDRRLVVDAFARYRITDVRRFREAVGVGSEAAAESRLDNIMR
HCCEEEEEEECCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
DQTREVLGTVSSNDILSSDRAALMLRIRNGAIAQARDLGLEVIDVRLKRTDLPQANLEAT
HHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHCCCEEEEEEEHHCCCCCCHHHHH
FARMRAEREREAADEIARGEEAAQRVRAQADRTEVELVSEAEREAEVIRGEADAERNNIF
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCEE
AEAYGADPEFFEFYRSLTAYARALQGGNSSLVLSPDNEFFNYLKSSDGAGRVQQ
EEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNRSVILLVLLGAIVVGALSSLFIVDEREKALVLRFGRVVNVQEDPGLAFKLPFVDEVVK
CCCHHHHHHHHHHHHHHHHHHHEEECCCCHHHHEECCCEEEEECCCCCEEECCHHHHHHH
YDDRILSLEVGPLEVTPLDDRRLVVDAFARYRITDVRRFREAVGVGSEAAAESRLDNIMR
HCCEEEEEEECCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
DQTREVLGTVSSNDILSSDRAALMLRIRNGAIAQARDLGLEVIDVRLKRTDLPQANLEAT
HHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHCCCEEEEEEEHHCCCCCCHHHHH
FARMRAEREREAADEIARGEEAAQRVRAQADRTEVELVSEAEREAEVIRGEADAERNNIF
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCEE
AEAYGADPEFFEFYRSLTAYARALQGGNSSLVLSPDNEFFNYLKSSDGAGRVQQ
EEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]