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The map label for this gene is betI [H]

Identifier: 99081726

GI number: 99081726

Start: 1985642

End: 1986232

Strand: Direct

Name: betI [H]

Synonym: TM1040_1885

Alternate gene names: 99081726

Gene position: 1985642-1986232 (Clockwise)

Preceding gene: 99081722

Following gene: 99081729

Centisome position: 62.03

GC content: 61.25

Gene sequence:

>591_bases
ATGGCACGTAAACGCATTCGCGACATCCGCAACGAAGAGCTTATTGAAGCAACGATCATCACCGTCCACAAACGTGGCTA
CGGGACTGTAACCATGGCGGAAATCGCGCGTGAAGCCGGGGCTTCGGCAGCGTCGATCAGCTATTATTTCGGCTCCAAGG
AAGGGCTGATGGAAGCCACAATGCGACATCTGTTGCGCAAGCTGCGCAAGGCGATGGTCGAGGGCTATGCGCAGGCCCGA
TCACCACTGGAGCGGCTCTATGCAGTGATGGATGCGAACTTTGCAGATTCGCTGTATAGCGTGCCGCAATGCAGCATCTG
GATGCAGTTCTGGGCCAATGCGCCCTACTCTCCCAGTCTTGCCCGGCTGCACCGGATCAACCGCGCGCGGGTGCGCAGCC
ATTTTGTCGCCGAGTTGAGCCAATTGGTGCCCGCCGATCAGGTGGAAACCGCGCGCCAGGCCCTGCAGAGCTATATGGAT
GGCGTCTGGCTGCAGGCCGCGCAATCGGAACAGCCGCTGGACACTGAGGCGGCCCGCACTGCGGCGCATCGGGTGGTGGA
TCTCGTCACCTCGCGCGCGCTGGCGGCCTAA

Upstream 100 bases:

>100_bases
CTCGCCTGAATAAACTAACCAAATTTTGAATGGTCATTCAAGTTTTGGTTTTTCGAGGACAAATATTGAATAATCCGCCG
CAGTGGCGCAGTCTGATTTT

Downstream 100 bases:

>100_bases
GCGCAGGGCGCAGCCCATGCGCCGGGGCGCTGCCCCGGACCCCGGGATATTTGAGGTTAGAAGAAGGCCGCGGGCTCAGC
CCTCGCGGCGGTAGACCAGT

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MARKRIRDIRNEELIEATIITVHKRGYGTVTMAEIAREAGASAASISYYFGSKEGLMEATMRHLLRKLRKAMVEGYAQAR
SPLERLYAVMDANFADSLYSVPQCSIWMQFWANAPYSPSLARLHRINRARVRSHFVAELSQLVPADQVETARQALQSYMD
GVWLQAAQSEQPLDTEAARTAAHRVVDLVTSRALAA

Sequences:

>Translated_196_residues
MARKRIRDIRNEELIEATIITVHKRGYGTVTMAEIAREAGASAASISYYFGSKEGLMEATMRHLLRKLRKAMVEGYAQAR
SPLERLYAVMDANFADSLYSVPQCSIWMQFWANAPYSPSLARLHRINRARVRSHFVAELSQLVPADQVETARQALQSYMD
GVWLQAAQSEQPLDTEAARTAAHRVVDLVTSRALAA
>Mature_195_residues
ARKRIRDIRNEELIEATIITVHKRGYGTVTMAEIAREAGASAASISYYFGSKEGLMEATMRHLLRKLRKAMVEGYAQARS
PLERLYAVMDANFADSLYSVPQCSIWMQFWANAPYSPSLARLHRINRARVRSHFVAELSQLVPADQVETARQALQSYMDG
VWLQAAQSEQPLDTEAARTAAHRVVDLVTSRALAA

Specific function: Repressor involved in choline regulation of the bet genes [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786505, Length=187, Percent_Identity=35.2941176470588, Blast_Score=119, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR017757
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 21999; Mature: 21868

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS01081 HTH_TETR_1 ; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARKRIRDIRNEELIEATIITVHKRGYGTVTMAEIAREAGASAASISYYFGSKEGLMEAT
CCHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHH
MRHLLRKLRKAMVEGYAQARSPLERLYAVMDANFADSLYSVPQCSIWMQFWANAPYSPSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHCCCCCCHHH
ARLHRINRARVRSHFVAELSQLVPADQVETARQALQSYMDGVWLQAAQSEQPLDTEAART
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
AAHRVVDLVTSRALAA
HHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ARKRIRDIRNEELIEATIITVHKRGYGTVTMAEIAREAGASAASISYYFGSKEGLMEAT
CHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHH
MRHLLRKLRKAMVEGYAQARSPLERLYAVMDANFADSLYSVPQCSIWMQFWANAPYSPSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHCCCCCCHHH
ARLHRINRARVRSHFVAELSQLVPADQVETARQALQSYMDGVWLQAAQSEQPLDTEAART
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
AAHRVVDLVTSRALAA
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA