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The map label for this gene is dctB [H]

Identifier: 99081656

GI number: 99081656

Start: 1907502

End: 1909253

Strand: Reverse

Name: dctB [H]

Synonym: TM1040_1815

Alternate gene names: 99081656

Gene position: 1909253-1907502 (Counterclockwise)

Preceding gene: 99081667

Following gene: 99081655

Centisome position: 59.65

GC content: 64.33

Gene sequence:

>1752_bases
ATGTTAAATCCTCGACACCCCCGTCTCGCGCTGGTCGCCAGTGTTGTGCTCTTCATTGTCGTGCTCTCTGCGGTGGTCTG
GTCTTCGGCCTATCGACAGGCGCTGACGGCGCTGGCCGAACGCAGCGCCTCTGATCTCGCGCTGGCCTCGGATCGGGTGA
GCACGCAGTTGCAGATTTTCCGCGAGCAGGCGGTTCTGGTTGTAGAGCACCCGGCGTTGCAGGCGCTCGAAACCCGCGAG
GGACCGGCACGCGCCACAGCGCTCTTGCGCCGGATCGCGGATAAATCCGGCGCACTTGATGTGTTTTACGCCGATGACTC
GGGGCGCGTGCTGGCCGCCGCCGAAGGCGTGGCTGGTTCAAACGTCTCGGGTCGGCGGTATTTTCGGCGCGCGATGCAGG
GGGCGATGGGCACGGAGCCCATGGTGCTACCCGAGAGCAAGCGACGGGCCTATTTCTTTGCCGCGCCGGATTTCGGCCCG
GATGGGCGCGTGCGGGGCACATTGGTGGTTGTTGCGGACATCGAGCTGGTGGAGCAGACGTGGCGCGGCACCCTGCCGCC
GGTCTATTTCACCATCGAGGACGGACGCGTCTTTATCTCCAACCGGTTTGAGCTGCTGTTCTGGCGACTGGATGACGACA
AGACCGGGCTGATGACCGCAGATGGGGGCGATTTGCCGCTCGAGGTGAAAAAAGTGGGCGAACACGAGATCTGGCAACAG
CGTTGGAGCCCGTATTTGCCCGATGAGGCGCTTCATCTCGGGATCGGTCTGCCCGCCATCGGGATGCGCGGAGAGATCCT
CGTGGATGTGACCCCAGCGCAGCGGATCGCGGCGCTGCAGACCATGGCGATGGCTGCGGTCTGTCTTGCGTTTGGCACCA
TCCTGTTCTGGCTGGCAGAGCGGCGCCGCACGCTGGCAAAGGCCAATGCGGAACTGGAAGAGCGTGTCGAGACGCGCACC
CGGGCGCTGTCGGACACCAACCTGCAGCTGCGCCGCGAGGTGCGCGAACGCAAGGAGGCGGAGGCCGCATTGAAACAGGC
GCAGGCCGAACTGGTGCAGGCCGACAAGCTCTCGGCGCTGGGGCAGATGTCGGCTGGCATCAGTCATGAGCTCAACCAGC
CCTTGATGGCGATCCAGCAGTTTGCCGAGAACGGTCAGGCCTTTCTGGAGCGTGGCAAATCGGAACGCGCGGGCGAGAAC
CTCACCCGGATTGCGCAGATGTCGGCCCGGATGGCGCGCATCATCAAGAATCTGCGCGCCTTTGCCCGCAACGAGAGCGA
GCCGGTGGGGCGCGTGGATCTGGTGCAGGTCATCGAGGCGGCGGTGGAACTGACAGAGACCCGCCTGCGCGACCATGACG
TGACGCTGGACTGGCAACGCCCGGAGGCGCAGTCCGTCTGGGTGCGCGGTGGCGAGGTGCGGCTGACGCAGGTGTTTGTG
AACCTCATCAACAACGCCGTGGATGCGATGATGGGACAGGAGGAGCGCCGCGTGCGGATCGTCATCAACGATGGCGCGCG
GCTCACGGTGGGCGTGCGCGACATTGGCCCCGGTCTGAAACAGCCCGAAAAGGTCTTTGAGCCGTTCTACTCCACCAAGG
CGGTGGGGAGTTCGGAAGGCATGGGGCTGGGGCTGTCCATTTCCTACGGACTGGTGCAAAGCTTTGGCGGCAATATCCGG
GGCACCAACACAGAGCACGGCGCCCTGTTCACGGTCGAACTGGACTACTGGAAAGAGGAAACCGCCGCATGA

Upstream 100 bases:

>100_bases
ACAAAGTCCGGGTCGGTCGGGGATTGGGTCAGTGTTTTCATAAAATCGGTTTTTGCCGAGGTCTCTGGTCTTGGCAAGGG
GGGCTTTGTAATGTGGCGCA

Downstream 100 bases:

>100_bases
CGCGCAAGGTGCTGTTGGTTGATGATGATGCGGCCGTTCGCGAGGCGCTGGGCCAGACGCTCGAGCTTGCCGATCTCAAC
GCGGTGACGGCGGGGTCGTT

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 583; Mature: 583

Protein sequence:

>583_residues
MLNPRHPRLALVASVVLFIVVLSAVVWSSAYRQALTALAERSASDLALASDRVSTQLQIFREQAVLVVEHPALQALETRE
GPARATALLRRIADKSGALDVFYADDSGRVLAAAEGVAGSNVSGRRYFRRAMQGAMGTEPMVLPESKRRAYFFAAPDFGP
DGRVRGTLVVVADIELVEQTWRGTLPPVYFTIEDGRVFISNRFELLFWRLDDDKTGLMTADGGDLPLEVKKVGEHEIWQQ
RWSPYLPDEALHLGIGLPAIGMRGEILVDVTPAQRIAALQTMAMAAVCLAFGTILFWLAERRRTLAKANAELEERVETRT
RALSDTNLQLRREVRERKEAEAALKQAQAELVQADKLSALGQMSAGISHELNQPLMAIQQFAENGQAFLERGKSERAGEN
LTRIAQMSARMARIIKNLRAFARNESEPVGRVDLVQVIEAAVELTETRLRDHDVTLDWQRPEAQSVWVRGGEVRLTQVFV
NLINNAVDAMMGQEERRVRIVINDGARLTVGVRDIGPGLKQPEKVFEPFYSTKAVGSSEGMGLGLSISYGLVQSFGGNIR
GTNTEHGALFTVELDYWKEETAA

Sequences:

>Translated_583_residues
MLNPRHPRLALVASVVLFIVVLSAVVWSSAYRQALTALAERSASDLALASDRVSTQLQIFREQAVLVVEHPALQALETRE
GPARATALLRRIADKSGALDVFYADDSGRVLAAAEGVAGSNVSGRRYFRRAMQGAMGTEPMVLPESKRRAYFFAAPDFGP
DGRVRGTLVVVADIELVEQTWRGTLPPVYFTIEDGRVFISNRFELLFWRLDDDKTGLMTADGGDLPLEVKKVGEHEIWQQ
RWSPYLPDEALHLGIGLPAIGMRGEILVDVTPAQRIAALQTMAMAAVCLAFGTILFWLAERRRTLAKANAELEERVETRT
RALSDTNLQLRREVRERKEAEAALKQAQAELVQADKLSALGQMSAGISHELNQPLMAIQQFAENGQAFLERGKSERAGEN
LTRIAQMSARMARIIKNLRAFARNESEPVGRVDLVQVIEAAVELTETRLRDHDVTLDWQRPEAQSVWVRGGEVRLTQVFV
NLINNAVDAMMGQEERRVRIVINDGARLTVGVRDIGPGLKQPEKVFEPFYSTKAVGSSEGMGLGLSISYGLVQSFGGNIR
GTNTEHGALFTVELDYWKEETAA
>Mature_583_residues
MLNPRHPRLALVASVVLFIVVLSAVVWSSAYRQALTALAERSASDLALASDRVSTQLQIFREQAVLVVEHPALQALETRE
GPARATALLRRIADKSGALDVFYADDSGRVLAAAEGVAGSNVSGRRYFRRAMQGAMGTEPMVLPESKRRAYFFAAPDFGP
DGRVRGTLVVVADIELVEQTWRGTLPPVYFTIEDGRVFISNRFELLFWRLDDDKTGLMTADGGDLPLEVKKVGEHEIWQQ
RWSPYLPDEALHLGIGLPAIGMRGEILVDVTPAQRIAALQTMAMAAVCLAFGTILFWLAERRRTLAKANAELEERVETRT
RALSDTNLQLRREVRERKEAEAALKQAQAELVQADKLSALGQMSAGISHELNQPLMAIQQFAENGQAFLERGKSERAGEN
LTRIAQMSARMARIIKNLRAFARNESEPVGRVDLVQVIEAAVELTETRLRDHDVTLDWQRPEAQSVWVRGGEVRLTQVFV
NLINNAVDAMMGQEERRVRIVINDGARLTVGVRDIGPGLKQPEKVFEPFYSTKAVGSSEGMGLGLSISYGLVQSFGGNIR
GTNTEHGALFTVELDYWKEETAA

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=235, Percent_Identity=30.2127659574468, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788549, Length=236, Percent_Identity=27.1186440677966, Blast_Score=79, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 64471; Mature: 64471

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNPRHPRLALVASVVLFIVVLSAVVWSSAYRQALTALAERSASDLALASDRVSTQLQIF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
REQAVLVVEHPALQALETREGPARATALLRRIADKSGALDVFYADDSGRVLAAAEGVAGS
HHCCEEEEECCHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEECCCCCC
NVSGRRYFRRAMQGAMGTEPMVLPESKRRAYFFAAPDFGPDGRVRGTLVVVADIELVEQT
CCCHHHHHHHHHHCCCCCCCEECCCCCCCEEEEECCCCCCCCCCEEEEEEEECHHHHHHH
WRGTLPPVYFTIEDGRVFISNRFELLFWRLDDDKTGLMTADGGDLPLEVKKVGEHEIWQQ
HCCCCCCEEEEEECCEEEEECCEEEEEEEECCCCCCEEEECCCCCCCHHHHCCHHHHHHH
RWSPYLPDEALHLGIGLPAIGMRGEILVDVTPAQRIAALQTMAMAAVCLAFGTILFWLAE
HCCCCCCCHHHEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRRTLAKANAELEERVETRTRALSDTNLQLRREVRERKEAEAALKQAQAELVQADKLSAL
HHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQMSAGISHELNQPLMAIQQFAENGQAFLERGKSERAGENLTRIAQMSARMARIIKNLRA
HHHHCCCHHHHCCHHHHHHHHHHCCHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHH
FARNESEPVGRVDLVQVIEAAVELTETRLRDHDVTLDWQRPEAQSVWVRGGEVRLTQVFV
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCHHHHHHH
NLINNAVDAMMGQEERRVRIVINDGARLTVGVRDIGPGLKQPEKVFEPFYSTKAVGSSEG
HHHHHHHHHHHCCCCCEEEEEEECCCEEEEEHHHCCCCCCCCHHHHHHHHHHHCCCCCCC
MGLGLSISYGLVQSFGGNIRGTNTEHGALFTVELDYWKEETAA
CCEEEEEHHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHCCCC
>Mature Secondary Structure
MLNPRHPRLALVASVVLFIVVLSAVVWSSAYRQALTALAERSASDLALASDRVSTQLQIF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
REQAVLVVEHPALQALETREGPARATALLRRIADKSGALDVFYADDSGRVLAAAEGVAGS
HHCCEEEEECCHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEECCCCCC
NVSGRRYFRRAMQGAMGTEPMVLPESKRRAYFFAAPDFGPDGRVRGTLVVVADIELVEQT
CCCHHHHHHHHHHCCCCCCCEECCCCCCCEEEEECCCCCCCCCCEEEEEEEECHHHHHHH
WRGTLPPVYFTIEDGRVFISNRFELLFWRLDDDKTGLMTADGGDLPLEVKKVGEHEIWQQ
HCCCCCCEEEEEECCEEEEECCEEEEEEEECCCCCCEEEECCCCCCCHHHHCCHHHHHHH
RWSPYLPDEALHLGIGLPAIGMRGEILVDVTPAQRIAALQTMAMAAVCLAFGTILFWLAE
HCCCCCCCHHHEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRRTLAKANAELEERVETRTRALSDTNLQLRREVRERKEAEAALKQAQAELVQADKLSAL
HHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQMSAGISHELNQPLMAIQQFAENGQAFLERGKSERAGENLTRIAQMSARMARIIKNLRA
HHHHCCCHHHHCCHHHHHHHHHHCCHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHH
FARNESEPVGRVDLVQVIEAAVELTETRLRDHDVTLDWQRPEAQSVWVRGGEVRLTQVFV
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCHHHHHHH
NLINNAVDAMMGQEERRVRIVINDGARLTVGVRDIGPGLKQPEKVFEPFYSTKAVGSSEG
HHHHHHHHHHHCCCCCEEEEEEECCCEEEEEHHHCCCCCCCCHHHHHHHHHHHCCCCCCC
MGLGLSISYGLVQSFGGNIRGTNTEHGALFTVELDYWKEETAA
CCEEEEEHHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431; 2551890; 2695394 [H]