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The map label for this gene is infC [H]

Identifier: 99081604

GI number: 99081604

Start: 1853932

End: 1854345

Strand: Direct

Name: infC [H]

Synonym: TM1040_1763

Alternate gene names: 99081604

Gene position: 1853932-1854345 (Clockwise)

Preceding gene: 99081602

Following gene: 99081612

Centisome position: 57.92

GC content: 55.07

Gene sequence:

>414_bases
ATGCAGATGGCCGAAGAGGCCGGTCTTGACCTTGTCGAGATCTCGCCAAACGCCACGCCGCCGGTCTGCAAGATCATGGA
CTTCGGCAAGTTCAAGTATGAACAGCAAAAACGCGAGAGCGAAGCGCGCAAGAAGCAGAAGATCATCGAGGTCAAAGAGG
TCAAGTTCCGTCCCAACACGGATACCCATGACTACGATGTGAAGATGCGCAACGTGATCAAGTTCCTGGAGAACGGAGAT
AAGGTCAAAGTGACCCTGCGATTCCGTGGCCGCGAGATGGCGCACCAGAACCTGGGACGTGAGCTGCTTCAGCGCGTTGC
CGAAGACATCAAGGAACTCGGCAAGGTCGAAAACATGCCGAAGATGGAGGGCCGTCAGATGATCATGATGATCGGCCCGC
TTCCGAGCAAGTAA

Upstream 100 bases:

>100_bases
TGACACTGGCCCGCGCGTCAACGACAAAATCCGCGCTCCCGAAATCCGCCTGATCGGGGCTGAAGGCGAAAACGTCGGCG
TTGTGCATCCCGCCAAGGCG

Downstream 100 bases:

>100_bases
TACCCCCTGACGGGGCCCCGCATGACGCAGGTCACGGTGCCCGGTTGCACATAAAAAAAGCCTCCCTTGATACGCAAGGG
AGGCTTTTTAGCTTTCAATG

Product: translation initiation factor 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 137; Mature: 137

Protein sequence:

>137_residues
MQMAEEAGLDLVEISPNATPPVCKIMDFGKFKYEQQKRESEARKKQKIIEVKEVKFRPNTDTHDYDVKMRNVIKFLENGD
KVKVTLRFRGREMAHQNLGRELLQRVAEDIKELGKVENMPKMEGRQMIMMIGPLPSK

Sequences:

>Translated_137_residues
MQMAEEAGLDLVEISPNATPPVCKIMDFGKFKYEQQKRESEARKKQKIIEVKEVKFRPNTDTHDYDVKMRNVIKFLENGD
KVKVTLRFRGREMAHQNLGRELLQRVAEDIKELGKVENMPKMEGRQMIMMIGPLPSK
>Mature_137_residues
MQMAEEAGLDLVEISPNATPPVCKIMDFGKFKYEQQKRESEARKKQKIIEVKEVKFRPNTDTHDYDVKMRNVIKFLENGD
KVKVTLRFRGREMAHQNLGRELLQRVAEDIKELGKVENMPKMEGRQMIMMIGPLPSK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=134, Percent_Identity=64.9253731343284, Blast_Score=171, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 15978; Mature: 15978

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
7.3 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
7.3 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMAEEAGLDLVEISPNATPPVCKIMDFGKFKYEQQKRESEARKKQKIIEVKEVKFRPNT
CCCCHHHCCEEEEECCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCC
DTHDYDVKMRNVIKFLENGDKVKVTLRFRGREMAHQNLGRELLQRVAEDIKELGKVENMP
CCCCHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KMEGRQMIMMIGPLPSK
CCCCCEEEEEECCCCCC
>Mature Secondary Structure
MQMAEEAGLDLVEISPNATPPVCKIMDFGKFKYEQQKRESEARKKQKIIEVKEVKFRPNT
CCCCHHHCCEEEEECCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCC
DTHDYDVKMRNVIKFLENGDKVKVTLRFRGREMAHQNLGRELLQRVAEDIKELGKVENMP
CCCCHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KMEGRQMIMMIGPLPSK
CCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA