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The map label for this gene is cutL [H]

Identifier: 99081546

GI number: 99081546

Start: 1800686

End: 1802995

Strand: Reverse

Name: cutL [H]

Synonym: TM1040_1705

Alternate gene names: 99081546

Gene position: 1802995-1800686 (Counterclockwise)

Preceding gene: 99081556

Following gene: 99081545

Centisome position: 56.33

GC content: 61.3

Gene sequence:

>2310_bases
ATGAACCAACGGGTCGAAAAATTTGGGAAGAGTCAGCCGCTCGCACGGGTGGAGGACCAGCGTCTGCTGACCGGACAGGG
GCGCTACATCGAGGATACCATGCCTGCGGGGGCATTGCGGGCCTATGTGTTTCGCAGCCCCGTCGCGCATGGCGAGATCA
CCACGCTCAATGTCGATGATGCGCGCGCAGCCGAAGGCGTGCATCTGGTGATTACGCAGGCCGATCTGGTTGATGCGGGG
ATTGAGGCCACGCTTGATGGTGCTTTGGTCAAGAATATTGACGGCAGCAAGGCTGCAGCTCCCGAACGGCCGGTGCTGGC
AGGGCACCGCGTGCGCTATGTCGGGGAGCCCGTGGCCGTGGTCATCGCCGACACCATGGATCAGGCGCGTGACGCCGCCG
AATTGATCGAGTTTGACTACGAGGATCTCGACGTGAAGCTAGATCTGGCCGCAGGCGGCGCAGAGATTCATCCCGAGGCA
CCTCAGAATCGCGCCTTCAACTGGGGGCTTGGCGACAAGGCTGCAACCGATGCGGCCTTTGAAGCTGCCGCTCATACGGT
CAGCCTGCAGGTCGACGACAACCGCATCATCGTCAACGCGATGGAGCCACGCGGCTGTCACGCCACCTGGCAGGATGGGC
GCATGCATTTTTACTATGGCGGGCAGGGCGTCTGGTCCATGAAGGAGCAGTTGGCCAAGAAAATGCATCTCCCCGCCGAA
GATGTACATGTGGTGACGCCGGATGTGGGCGGCGGCTTTGGCATGAAAGCAATGCCCTATCCGGAGTATTTTGCCGTCGC
CTATGCAGCCAAGGTGCTGGAGCGGCCCGTGGGCTGGATGTCGGATCGCACCGAAGCCATGCTGAGCGACAATGGCGGGC
GGGATCTCACCTCTCTGGCCGAGCTGGCCTTTGACGCGGATCTGAAGATCACGGCTTACCGCGTCCATACGCATTGCAAT
CTCGGCGCCTATAACTCTCATTTTGGCCAGCCCATTCAGACCCAGCTGTTTTCTCGGGTGCTGGCAGGGGTTTACGACAT
CCAGACCGCGTGGCTCGAAGTGGATGGGATCTATACCAACACCACGCAGGTGGATGCGTATCGCGGGGCGGGGCGGCCCG
AGGCGATTTATGTGCTCGAGCGGGTCATCGACCGGGCGGCGCGCGATCTTGGCGTTGATCCGATGGACCTGAGGCGCAGG
AACTTCATCGCGCCGCAAAAGTTTCCCTACAAGACCGTCACCGATGAGACCTATGACGTGGGGGATTTCAACCTCGTGCT
CGACCGTCTCATCAAAGAATCGGATCTGGCCGGGTTCGAGGCGCGGCGCGCGCAGGACGCGGCAGAAGGTCGTTACCGGG
GCGCGGGCCTTTGTTACTATATCGAAAGTATTTTGGGCGATCCTTCAGAGACTGCAGACGTCGAGTTTCTGGAGGACGGC
CGGGTGAACATCTATGTGGGTACGCAAAGCAACGGGCAAGGGCATGAAACTGTCTTTGCGACGTTCCTTGCGGACCAGAC
CGGCATCCCCGTCAGCGCCATTTCGGTTGTCCAGGGCGACAGTGACCGCATCGCCAAGGGCGGCGGGACCGGCGGCTCTC
GTTCCGTGACCACACAGGCCAATGCCACATTGGCCACCGTCGACAAGATGGTGGCCGCCTTCACCCCCTTCCTTGCCGAA
GAAATGGGCGTGGATGAGGAGGCTGTCGACTTTGATGGTGAGACCTTCCGCGCGCCGGGGTCCAATCTCACCCCGACGGT
GCTTGAGGCGGCTGACCTGGCCCGTGAAAAGGGGCGCGTAGACCTGTTGCGCCATCAGGCCGAAGCATCACTGCCGGGAC
GTTCCTTCCCCAACGGGGCCCATCTCGCCGAGGTCGTGATCGACCGTGAAACCGGGCAGGCCCGCGTTGACCGCTATACG
GTGGTTGATGATTTTGGAAATCTTATCAACCCCATGCTGGCCGAAGGTCAGGTGCATGGCGGGGTCGCTCAGGGGCTAGG
GCAGGCAATGCTTGAACATGTGGTCTACGACGCGGATGGCCAGTTGCTCACGGCAACGTTCATGGACTACGCGATGCCGC
GCGCCGAAGATATGCCTTGGGTGGATTTCACCTCGGAGCCGGTGCCATCGACGCAGAACCCGATGGGAATGAAGGGCTGC
GGCGAGGCGGGCACGGTTGGGGCCCTCGCAGCAGTGGCCAATGCGGTTCAGGATGCGCTCTGGGATCAGGGCATCCGGCA
GGTGGATATGCCGTTCACGCCGGTCAAACTTTGGGAGTTGATGAGGGATGTTTCTCAAGCGGCTGAGTAA

Upstream 100 bases:

>100_bases
AGGCAGAAATTTCTTACACCACGGGCGCGGGATCACTGGACAAGCCTGTCGCGCACAGTAGGCTCCGCCCAAGCTGAGCG
CAGGCAAAGGGAGCCATCCG

Downstream 100 bases:

>100_bases
ATCAGTTCTGGGAGTGTTCGGGCGGCGTCGGCTGCTGTCCGCGCACTCGTCAGAGACCGCTTCGCGCGGTCCGCAATCTC
ATGTGATCATCCTTGACGGC

Product: xanthine dehydrogenase, molybdenum binding subunit apoprotein

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 769; Mature: 769

Protein sequence:

>769_residues
MNQRVEKFGKSQPLARVEDQRLLTGQGRYIEDTMPAGALRAYVFRSPVAHGEITTLNVDDARAAEGVHLVITQADLVDAG
IEATLDGALVKNIDGSKAAAPERPVLAGHRVRYVGEPVAVVIADTMDQARDAAELIEFDYEDLDVKLDLAAGGAEIHPEA
PQNRAFNWGLGDKAATDAAFEAAAHTVSLQVDDNRIIVNAMEPRGCHATWQDGRMHFYYGGQGVWSMKEQLAKKMHLPAE
DVHVVTPDVGGGFGMKAMPYPEYFAVAYAAKVLERPVGWMSDRTEAMLSDNGGRDLTSLAELAFDADLKITAYRVHTHCN
LGAYNSHFGQPIQTQLFSRVLAGVYDIQTAWLEVDGIYTNTTQVDAYRGAGRPEAIYVLERVIDRAARDLGVDPMDLRRR
NFIAPQKFPYKTVTDETYDVGDFNLVLDRLIKESDLAGFEARRAQDAAEGRYRGAGLCYYIESILGDPSETADVEFLEDG
RVNIYVGTQSNGQGHETVFATFLADQTGIPVSAISVVQGDSDRIAKGGGTGGSRSVTTQANATLATVDKMVAAFTPFLAE
EMGVDEEAVDFDGETFRAPGSNLTPTVLEAADLAREKGRVDLLRHQAEASLPGRSFPNGAHLAEVVIDRETGQARVDRYT
VVDDFGNLINPMLAEGQVHGGVAQGLGQAMLEHVVYDADGQLLTATFMDYAMPRAEDMPWVDFTSEPVPSTQNPMGMKGC
GEAGTVGALAAVANAVQDALWDQGIRQVDMPFTPVKLWELMRDVSQAAE

Sequences:

>Translated_769_residues
MNQRVEKFGKSQPLARVEDQRLLTGQGRYIEDTMPAGALRAYVFRSPVAHGEITTLNVDDARAAEGVHLVITQADLVDAG
IEATLDGALVKNIDGSKAAAPERPVLAGHRVRYVGEPVAVVIADTMDQARDAAELIEFDYEDLDVKLDLAAGGAEIHPEA
PQNRAFNWGLGDKAATDAAFEAAAHTVSLQVDDNRIIVNAMEPRGCHATWQDGRMHFYYGGQGVWSMKEQLAKKMHLPAE
DVHVVTPDVGGGFGMKAMPYPEYFAVAYAAKVLERPVGWMSDRTEAMLSDNGGRDLTSLAELAFDADLKITAYRVHTHCN
LGAYNSHFGQPIQTQLFSRVLAGVYDIQTAWLEVDGIYTNTTQVDAYRGAGRPEAIYVLERVIDRAARDLGVDPMDLRRR
NFIAPQKFPYKTVTDETYDVGDFNLVLDRLIKESDLAGFEARRAQDAAEGRYRGAGLCYYIESILGDPSETADVEFLEDG
RVNIYVGTQSNGQGHETVFATFLADQTGIPVSAISVVQGDSDRIAKGGGTGGSRSVTTQANATLATVDKMVAAFTPFLAE
EMGVDEEAVDFDGETFRAPGSNLTPTVLEAADLAREKGRVDLLRHQAEASLPGRSFPNGAHLAEVVIDRETGQARVDRYT
VVDDFGNLINPMLAEGQVHGGVAQGLGQAMLEHVVYDADGQLLTATFMDYAMPRAEDMPWVDFTSEPVPSTQNPMGMKGC
GEAGTVGALAAVANAVQDALWDQGIRQVDMPFTPVKLWELMRDVSQAAE
>Mature_769_residues
MNQRVEKFGKSQPLARVEDQRLLTGQGRYIEDTMPAGALRAYVFRSPVAHGEITTLNVDDARAAEGVHLVITQADLVDAG
IEATLDGALVKNIDGSKAAAPERPVLAGHRVRYVGEPVAVVIADTMDQARDAAELIEFDYEDLDVKLDLAAGGAEIHPEA
PQNRAFNWGLGDKAATDAAFEAAAHTVSLQVDDNRIIVNAMEPRGCHATWQDGRMHFYYGGQGVWSMKEQLAKKMHLPAE
DVHVVTPDVGGGFGMKAMPYPEYFAVAYAAKVLERPVGWMSDRTEAMLSDNGGRDLTSLAELAFDADLKITAYRVHTHCN
LGAYNSHFGQPIQTQLFSRVLAGVYDIQTAWLEVDGIYTNTTQVDAYRGAGRPEAIYVLERVIDRAARDLGVDPMDLRRR
NFIAPQKFPYKTVTDETYDVGDFNLVLDRLIKESDLAGFEARRAQDAAEGRYRGAGLCYYIESILGDPSETADVEFLEDG
RVNIYVGTQSNGQGHETVFATFLADQTGIPVSAISVVQGDSDRIAKGGGTGGSRSVTTQANATLATVDKMVAAFTPFLAE
EMGVDEEAVDFDGETFRAPGSNLTPTVLEAADLAREKGRVDLLRHQAEASLPGRSFPNGAHLAEVVIDRETGQARVDRYT
VVDDFGNLINPMLAEGQVHGGVAQGLGQAMLEHVVYDADGQLLTATFMDYAMPRAEDMPWVDFTSEPVPSTQNPMGMKGC
GEAGTVGALAAVANAVQDALWDQGIRQVDMPFTPVKLWELMRDVSQAAE

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=787, Percent_Identity=24.0152477763659, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI91823271, Length=800, Percent_Identity=23.125, Blast_Score=118, Evalue=3e-26,
Organism=Escherichia coli, GI1789230, Length=772, Percent_Identity=28.3678756476684, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1789246, Length=829, Percent_Identity=24.7285886610374, Blast_Score=196, Evalue=6e-51,
Organism=Escherichia coli, GI1786478, Length=780, Percent_Identity=27.4358974358974, Blast_Score=154, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17539860, Length=778, Percent_Identity=22.6221079691517, Blast_Score=125, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI32566215, Length=562, Percent_Identity=25.4448398576512, Blast_Score=115, Evalue=9e-26,
Organism=Drosophila melanogaster, GI17737937, Length=763, Percent_Identity=24.1153342070773, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24647201, Length=687, Percent_Identity=23.72634643377, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24647195, Length=783, Percent_Identity=23.3716475095785, Blast_Score=90, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24647197, Length=807, Percent_Identity=24.4114002478315, Blast_Score=89, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 83442; Mature: 83442

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQRVEKFGKSQPLARVEDQRLLTGQGRYIEDTMPAGALRAYVFRSPVAHGEITTLNVDD
CCCHHHHHCCCCCCHHHCCCEEECCCCCEECCCCCHHHHHHHHHHCCCCCCCEEEEECCC
ARAAEGVHLVITQADLVDAGIEATLDGALVKNIDGSKAAAPERPVLAGHRVRYVGEPVAV
HHHCCCEEEEEEECHHHHCCCHHHHCCHHHCCCCCCCCCCCCCCCCCCCEEEECCCCEEE
VIADTMDQARDAAELIEFDYEDLDVKLDLAAGGAEIHPEAPQNRAFNWGLGDKAATDAAF
EEEHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEECCCCCCCCCEECCCCCCHHHHHHH
EAAAHTVSLQVDDNRIIVNAMEPRGCHATWQDGRMHFYYGGQGVWSMKEQLAKKMHLPAE
HHHEEEEEEEECCCEEEEEECCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCC
DVHVVTPDVGGGFGMKAMPYPEYFAVAYAAKVLERPVGWMSDRTEAMLSDNGGRDLTSLA
CCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCHHHHHH
ELAFDADLKITAYRVHTHCNLGAYNSHFGQPIQTQLFSRVLAGVYDIQTAWLEVDGIYTN
HHHHCCCCEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEECCEEEC
TTQVDAYRGAGRPEAIYVLERVIDRAARDLGVDPMDLRRRNFIAPQKFPYKTVTDETYDV
CEEEEHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCC
GDFNLVLDRLIKESDLAGFEARRAQDAAEGRYRGAGLCYYIESILGDPSETADVEFLEDG
CHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCC
RVNIYVGTQSNGQGHETVFATFLADQTGIPVSAISVVQGDSDRIAKGGGTGGSRSVTTQA
EEEEEEECCCCCCCCHHEEEEEHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEEECC
NATLATVDKMVAAFTPFLAEEMGVDEEAVDFDGETFRAPGSNLTPTVLEAADLAREKGRV
CCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCH
DLLRHQAEASLPGRSFPNGAHLAEVVIDRETGQARVDRYTVVDDFGNLINPMLAEGQVHG
HHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCHHHEEEEHHHHHHHHHHHHHCCCCCC
GVAQGLGQAMLEHVVYDADGQLLTATFMDYAMPRAEDMPWVDFTSEPVPSTQNPMGMKGC
HHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GEAGTVGALAAVANAVQDALWDQGIRQVDMPFTPVKLWELMRDVSQAAE
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNQRVEKFGKSQPLARVEDQRLLTGQGRYIEDTMPAGALRAYVFRSPVAHGEITTLNVDD
CCCHHHHHCCCCCCHHHCCCEEECCCCCEECCCCCHHHHHHHHHHCCCCCCCEEEEECCC
ARAAEGVHLVITQADLVDAGIEATLDGALVKNIDGSKAAAPERPVLAGHRVRYVGEPVAV
HHHCCCEEEEEEECHHHHCCCHHHHCCHHHCCCCCCCCCCCCCCCCCCCEEEECCCCEEE
VIADTMDQARDAAELIEFDYEDLDVKLDLAAGGAEIHPEAPQNRAFNWGLGDKAATDAAF
EEEHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEECCCCCCCCCEECCCCCCHHHHHHH
EAAAHTVSLQVDDNRIIVNAMEPRGCHATWQDGRMHFYYGGQGVWSMKEQLAKKMHLPAE
HHHEEEEEEEECCCEEEEEECCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCC
DVHVVTPDVGGGFGMKAMPYPEYFAVAYAAKVLERPVGWMSDRTEAMLSDNGGRDLTSLA
CCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCHHHHHH
ELAFDADLKITAYRVHTHCNLGAYNSHFGQPIQTQLFSRVLAGVYDIQTAWLEVDGIYTN
HHHHCCCCEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEECCEEEC
TTQVDAYRGAGRPEAIYVLERVIDRAARDLGVDPMDLRRRNFIAPQKFPYKTVTDETYDV
CEEEEHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCC
GDFNLVLDRLIKESDLAGFEARRAQDAAEGRYRGAGLCYYIESILGDPSETADVEFLEDG
CHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCC
RVNIYVGTQSNGQGHETVFATFLADQTGIPVSAISVVQGDSDRIAKGGGTGGSRSVTTQA
EEEEEEECCCCCCCCHHEEEEEHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEEECC
NATLATVDKMVAAFTPFLAEEMGVDEEAVDFDGETFRAPGSNLTPTVLEAADLAREKGRV
CCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCH
DLLRHQAEASLPGRSFPNGAHLAEVVIDRETGQARVDRYTVVDDFGNLINPMLAEGQVHG
HHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCHHHEEEEHHHHHHHHHHHHHCCCCCC
GVAQGLGQAMLEHVVYDADGQLLTATFMDYAMPRAEDMPWVDFTSEPVPSTQNPMGMKGC
HHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GEAGTVGALAAVANAVQDALWDQGIRQVDMPFTPVKLWELMRDVSQAAE
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]