Click here to switch to the map view.

The map label for this gene is dinF [H]

Identifier: 99081392

GI number: 99081392

Start: 1658100

End: 1659422

Strand: Reverse

Name: dinF [H]

Synonym: TM1040_1551

Alternate gene names: 99081392

Gene position: 1659422-1658100 (Counterclockwise)

Preceding gene: 99081393

Following gene: 99081389

Centisome position: 51.84

GC content: 62.74

Gene sequence:

>1323_bases
ATGTCGGAGGCGTCAGGCCCCATCACCCATTCCCGGGTGCTCAAGATCGCGTTGCCGATTGTTTTGTCCAATGCCACCGT
GCCGATCCTCGGCGCCGTCGACACCGGCGTGGTGGGACAACTTGGCGAAGCGGCCCCGATCGGAGCGGTGGGCGTTGGCA
CGGTCATTCTGTCGACGATCTACTGGGTCTTTGGCTTTTTGCGGATGGGCACCACCGGGCTGGCCTCGCAGGCGCGTGGC
GCCGGCGATCTGGCTGAGACGGGCGCGCTGCTGATGCGGGGGCTGCTCTTGGCCTTTGGGGCGGGTGCGTTTTTCATTGT
TGCTCAGGCGCTTGTGTTCTGGGGCGCATTTACGATTGCCCCTGCCAGCGCCGAGGTCGAGGAACTGGCGCGGCGCTATC
TCGAGATCCGAATCTGGGGCGCGCCCGCAACCATCGGGCTTTATGCGGTGACAGGCTGGCTGATCGCCATCGAGCGCACC
CGCGCCGTGTTCCTGCTGCAGATCTGGATGAATGGGCTCAATATCCTGCTGGATCTGTGGTTTGTGCTCGGGCTCGACTG
GGGGGTCGAGGGCGTGGCCATTGCGACCCTGATCGCAGAGTGTTCGGGGCTGGTGCTTGGACTTTGGTATTGCCGCTCAG
CCTTTGCGGGCGATCAATGGCATGACTGGGGCCGGATCTTTGACCGTGCGCGCCTCAAGCGGATGGTTCAGGTCAATGGC
GACATCATGGTGCGTTCGGTGCTGCTCACACTGTCGTTCACCACATTCTTGTTTCTCAGCGCGGATATGGGCGATGTGCG
GCTCGCCTCCAATCAGGTGTTGATTCAGTTTCTGCACATCACGGCCTTTGCGCTCGACGGGTTTGCCTTCAGCGCCGAGG
CGCTGGTGGGTGGGGCGGTCGGGGCGCGGGATCGTGGTCGGCTGCGTCGCGCCGCATTGGTATCGAGCTATTGGGGCATC
GGCTTTGCCGTGGCGCTCGGGGTGGGGTTCTGGCTGTGGGGGCCGTGGATTGTTGACCTGATGACAACCGCACCCGACGT
GCGCGAGACCGCGCGCGCCTACCTGATCTGGCTGGCGTTTGCGCCACTTCTGAGTGTCGCAAGCTATATGTTTGACGGGA
TCTTTATCGGCGCGACCTGGACACGCGACATGAGGATTGCCGCTTTGCAGTCGGTGGCTGTTTACGGCGTTGCGCTTGCA
ATTTGCGTGCCGATGTTTGGAAACCATGGATTGTGGATGGCGCTGATGGTGCTCAATGTCACACGCGCGCTGACTCTGGC
GCTGCGCTACCCAAGACTGGAGGCCGGCATCACCGCGCCCTGA

Upstream 100 bases:

>100_bases
ATGGCAGGACCATAAGGAAAAGCTCTTTGCACAAGCGACGGGTCATTTCCTGATGCCGCAGGAACGCCCCTCAGGCAACT
GATTTCAAAAGGAATACCCT

Downstream 100 bases:

>100_bases
AACCGCGCATCCGGCAGAAGAAAGCCAAGGGATCGCAGCCAAGTGAGCAACGCGGGTTCCGCTCTCATCTGGGCTGATAC
TTTAGAGGGGGTGCGCTCTG

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSEASGPITHSRVLKIALPIVLSNATVPILGAVDTGVVGQLGEAAPIGAVGVGTVILSTIYWVFGFLRMGTTGLASQARG
AGDLAETGALLMRGLLLAFGAGAFFIVAQALVFWGAFTIAPASAEVEELARRYLEIRIWGAPATIGLYAVTGWLIAIERT
RAVFLLQIWMNGLNILLDLWFVLGLDWGVEGVAIATLIAECSGLVLGLWYCRSAFAGDQWHDWGRIFDRARLKRMVQVNG
DIMVRSVLLTLSFTTFLFLSADMGDVRLASNQVLIQFLHITAFALDGFAFSAEALVGGAVGARDRGRLRRAALVSSYWGI
GFAVALGVGFWLWGPWIVDLMTTAPDVRETARAYLIWLAFAPLLSVASYMFDGIFIGATWTRDMRIAALQSVAVYGVALA
ICVPMFGNHGLWMALMVLNVTRALTLALRYPRLEAGITAP

Sequences:

>Translated_440_residues
MSEASGPITHSRVLKIALPIVLSNATVPILGAVDTGVVGQLGEAAPIGAVGVGTVILSTIYWVFGFLRMGTTGLASQARG
AGDLAETGALLMRGLLLAFGAGAFFIVAQALVFWGAFTIAPASAEVEELARRYLEIRIWGAPATIGLYAVTGWLIAIERT
RAVFLLQIWMNGLNILLDLWFVLGLDWGVEGVAIATLIAECSGLVLGLWYCRSAFAGDQWHDWGRIFDRARLKRMVQVNG
DIMVRSVLLTLSFTTFLFLSADMGDVRLASNQVLIQFLHITAFALDGFAFSAEALVGGAVGARDRGRLRRAALVSSYWGI
GFAVALGVGFWLWGPWIVDLMTTAPDVRETARAYLIWLAFAPLLSVASYMFDGIFIGATWTRDMRIAALQSVAVYGVALA
ICVPMFGNHGLWMALMVLNVTRALTLALRYPRLEAGITAP
>Mature_439_residues
SEASGPITHSRVLKIALPIVLSNATVPILGAVDTGVVGQLGEAAPIGAVGVGTVILSTIYWVFGFLRMGTTGLASQARGA
GDLAETGALLMRGLLLAFGAGAFFIVAQALVFWGAFTIAPASAEVEELARRYLEIRIWGAPATIGLYAVTGWLIAIERTR
AVFLLQIWMNGLNILLDLWFVLGLDWGVEGVAIATLIAECSGLVLGLWYCRSAFAGDQWHDWGRIFDRARLKRMVQVNGD
IMVRSVLLTLSFTTFLFLSADMGDVRLASNQVLIQFLHITAFALDGFAFSAEALVGGAVGARDRGRLRRAALVSSYWGIG
FAVALGVGFWLWGPWIVDLMTTAPDVRETARAYLIWLAFAPLLSVASYMFDGIFIGATWTRDMRIAALQSVAVYGVALAI
CVPMFGNHGLWMALMVLNVTRALTLALRYPRLEAGITAP

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790477, Length=423, Percent_Identity=40.661938534279, Blast_Score=218, Evalue=8e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 47407; Mature: 47276

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEASGPITHSRVLKIALPIVLSNATVPILGAVDTGVVGQLGEAAPIGAVGVGTVILSTI
CCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHCCCCCCCCCHHHHHHHHHHHH
YWVFGFLRMGTTGLASQARGAGDLAETGALLMRGLLLAFGAGAFFIVAQALVFWGAFTIA
HHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
PASAEVEELARRYLEIRIWGAPATIGLYAVTGWLIAIERTRAVFLLQIWMNGLNILLDLW
CCCHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHH
FVLGLDWGVEGVAIATLIAECSGLVLGLWYCRSAFAGDQWHDWGRIFDRARLKRMVQVNG
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCC
DIMVRSVLLTLSFTTFLFLSADMGDVRLASNQVLIQFLHITAFALDGFAFSAEALVGGAV
CHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHCCCCEEHHHHHCCCC
GARDRGRLRRAALVSSYWGIGFAVALGVGFWLWGPWIVDLMTTAPDVRETARAYLIWLAF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
APLLSVASYMFDGIFIGATWTRDMRIAALQSVAVYGVALAICVPMFGNHGLWMALMVLNV
HHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
TRALTLALRYPRLEAGITAP
HHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SEASGPITHSRVLKIALPIVLSNATVPILGAVDTGVVGQLGEAAPIGAVGVGTVILSTI
CCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHCCCCCCCCCHHHHHHHHHHHH
YWVFGFLRMGTTGLASQARGAGDLAETGALLMRGLLLAFGAGAFFIVAQALVFWGAFTIA
HHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
PASAEVEELARRYLEIRIWGAPATIGLYAVTGWLIAIERTRAVFLLQIWMNGLNILLDLW
CCCHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHH
FVLGLDWGVEGVAIATLIAECSGLVLGLWYCRSAFAGDQWHDWGRIFDRARLKRMVQVNG
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCC
DIMVRSVLLTLSFTTFLFLSADMGDVRLASNQVLIQFLHITAFALDGFAFSAEALVGGAV
CHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHCCCCEEHHHHHCCCC
GARDRGRLRRAALVSSYWGIGFAVALGVGFWLWGPWIVDLMTTAPDVRETARAYLIWLAF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
APLLSVASYMFDGIFIGATWTRDMRIAALQSVAVYGVALAICVPMFGNHGLWMALMVLNV
HHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
TRALTLALRYPRLEAGITAP
HHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]