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The map label for this gene is clpX [H]

Identifier: 99081367

GI number: 99081367

Start: 1629344

End: 1630609

Strand: Reverse

Name: clpX [H]

Synonym: TM1040_1526

Alternate gene names: 99081367

Gene position: 1630609-1629344 (Counterclockwise)

Preceding gene: 99081368

Following gene: 99081366

Centisome position: 50.94

GC content: 58.14

Gene sequence:

>1266_bases
ATGGCGACGAACTCGAGCGGCGACAGCAAGAACACGCTTTACTGTAGCTTCTGCGGCAAGAGCCAGCATGAGGTGAGAAA
GCTGATTGCAGGCCCGACCGTGTTCATCTGTGATGAATGCGTTGAGCTGTGCATGGACATCATCCGCGAGGAGACGAAGG
CCTCCGGGATGAAAGCAACCGACGGCGTGCCGACGCCCAAGGATATTTGCGAGGTCCTCGATGATTACGTGATCGGTCAG
GCGACGGCAAAGCGTGTGCTGTCGGTGGCGGTTCACAACCACTACAAGCGTCTGAACCACGCCCAGAAGGCCGGCAATGA
TATTGAACTTTCAAAGTCCAACATCCTGCTGATCGGCCCCACCGGCTGCGGTAAGACCCTTCTGGCGCAAACTCTTGCAC
GGATTCTGGACGTGCCGTTTACCATGGCAGATGCCACTACGCTTACAGAGGCAGGCTATGTTGGTGAGGATGTCGAGAAC
ATCATTCTGAAACTGCTGCAGGCGTCTGAATACAATGTCGAACGCGCGCAGCGCGGTATCGTCTACATCGACGAGGTCGA
CAAGATCACCCGCAAGTCTGAAAACCCCTCCATCACCCGTGATGTGTCGGGCGAGGGCGTGCAGCAGGCTCTGCTGAAAC
TGATGGAAGGCACTGTGGCCTCCGTGCCGCCGCAGGGTGGGCGCAAGCATCCCCAGCAGGAGTTCCTGCAGGTGGATACC
ACGAACATCCTCTTCATCTGCGGCGGTGCCTTTGCGGGCCTGGACAAGATCATCAAGCAGCGCGGCAAAGGCTCTGCGAT
GGGCTTTGGTGCCGATGTGCGCGAAGAGAGCGATGCGGGCGTGGGCGAGACCTTCCGCGATCTCGAGCCCGAAGATCTGC
TGAAATTCGGCCTGATCCCGGAATTCGTGGGCCGTTTGCCGGTTCTCGCGACGCTTGAGGATCTGGATGAGGATGCGCTG
ATCACCATCTTGACCAAGCCCAAGAATGCTTTGGTCAAACAATACCAGCGCCTCTTTGAACTTGAAGACACCGAGCTGGA
CTTCACCGATGAGGCGCTCTCGGCCATTGCCAAGAAAGCCATTGAGCGCAAGACCGGCGCGCGGGGTCTGCGCTCCATCC
TCGAGGATATCCTGCTCGATACCATGTTCGAGCTGCCCGGAATGGAGAGCGTGACAAAAGTGGTCGTCAATGAGGAGGCC
GTCTGCTCTGAGGCGCAGCCGCTGATGATCCACGCCGATGAAAAGGAATCGGCCACCGCAGGTTGA

Upstream 100 bases:

>100_bases
CACAATTTGACATTGTGGCCGCTTGGGAGCTGTCCTAAGCTGGCCTTACATCGGGGCAAATTGACACGCGCTGGCCCCGA
GGCGGATGGAAAGGTAGACC

Downstream 100 bases:

>100_bases
ACCGGTCCAAGGCTCCGATGAATACGAATAGCGAAAGGCCAGTGTCCCCGTGACACTGGCCTTTTTCTTTCTCAACTGCT
GGGTGTGTTAGGAGGGAACA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MATNSSGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREETKASGMKATDGVPTPKDICEVLDDYVIGQ
ATAKRVLSVAVHNHYKRLNHAQKAGNDIELSKSNILLIGPTGCGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVEN
IILKLLQASEYNVERAQRGIVYIDEVDKITRKSENPSITRDVSGEGVQQALLKLMEGTVASVPPQGGRKHPQQEFLQVDT
TNILFICGGAFAGLDKIIKQRGKGSAMGFGADVREESDAGVGETFRDLEPEDLLKFGLIPEFVGRLPVLATLEDLDEDAL
ITILTKPKNALVKQYQRLFELEDTELDFTDEALSAIAKKAIERKTGARGLRSILEDILLDTMFELPGMESVTKVVVNEEA
VCSEAQPLMIHADEKESATAG

Sequences:

>Translated_421_residues
MATNSSGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREETKASGMKATDGVPTPKDICEVLDDYVIGQ
ATAKRVLSVAVHNHYKRLNHAQKAGNDIELSKSNILLIGPTGCGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVEN
IILKLLQASEYNVERAQRGIVYIDEVDKITRKSENPSITRDVSGEGVQQALLKLMEGTVASVPPQGGRKHPQQEFLQVDT
TNILFICGGAFAGLDKIIKQRGKGSAMGFGADVREESDAGVGETFRDLEPEDLLKFGLIPEFVGRLPVLATLEDLDEDAL
ITILTKPKNALVKQYQRLFELEDTELDFTDEALSAIAKKAIERKTGARGLRSILEDILLDTMFELPGMESVTKVVVNEEA
VCSEAQPLMIHADEKESATAG
>Mature_420_residues
ATNSSGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREETKASGMKATDGVPTPKDICEVLDDYVIGQA
TAKRVLSVAVHNHYKRLNHAQKAGNDIELSKSNILLIGPTGCGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENI
ILKLLQASEYNVERAQRGIVYIDEVDKITRKSENPSITRDVSGEGVQQALLKLMEGTVASVPPQGGRKHPQQEFLQVDTT
NILFICGGAFAGLDKIIKQRGKGSAMGFGADVREESDAGVGETFRDLEPEDLLKFGLIPEFVGRLPVLATLEDLDEDALI
TILTKPKNALVKQYQRLFELEDTELDFTDEALSAIAKKAIERKTGARGLRSILEDILLDTMFELPGMESVTKVVVNEEAV
CSEAQPLMIHADEKESATAG

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=341, Percent_Identity=52.4926686217009, Blast_Score=325, Evalue=6e-89,
Organism=Escherichia coli, GI1786642, Length=424, Percent_Identity=68.6320754716981, Blast_Score=585, Evalue=1e-168,
Organism=Escherichia coli, GI1790366, Length=122, Percent_Identity=40.1639344262295, Blast_Score=96, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71982908, Length=310, Percent_Identity=49.0322580645161, Blast_Score=284, Evalue=7e-77,
Organism=Caenorhabditis elegans, GI71982905, Length=312, Percent_Identity=48.7179487179487, Blast_Score=283, Evalue=1e-76,
Organism=Caenorhabditis elegans, GI71988663, Length=391, Percent_Identity=38.1074168797954, Blast_Score=246, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI71988660, Length=247, Percent_Identity=39.6761133603239, Blast_Score=165, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6319704, Length=427, Percent_Identity=38.1733021077283, Blast_Score=266, Evalue=5e-72,
Organism=Drosophila melanogaster, GI24648289, Length=322, Percent_Identity=48.4472049689441, Blast_Score=296, Evalue=3e-80,
Organism=Drosophila melanogaster, GI24648291, Length=322, Percent_Identity=48.4472049689441, Blast_Score=295, Evalue=3e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 45850; Mature: 45719

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATNSSGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREETKASGMKAT
CCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DGVPTPKDICEVLDDYVIGQATAKRVLSVAVHNHYKRLNHAQKAGNDIELSKSNILLIGP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEEC
TGCGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQASEYNVERAQRGI
CCCCHHHHHHHHHHHHCCCCHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHCCC
VYIDEVDKITRKSENPSITRDVSGEGVQQALLKLMEGTVASVPPQGGRKHPQQEFLQVDT
EEEEHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCHHCCCCCCCCCCCHHHHHHHCC
TNILFICGGAFAGLDKIIKQRGKGSAMGFGADVREESDAGVGETFRDLEPEDLLKFGLIP
CCEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHCCCH
EFVGRLPVLATLEDLDEDALITILTKPKNALVKQYQRLFELEDTELDFTDEALSAIAKKA
HHHCCCCHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
IERKTGARGLRSILEDILLDTMFELPGMESVTKVVVNEEAVCSEAQPLMIHADEKESATA
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHCCCCCEEEECCCCCCCCC
G
C
>Mature Secondary Structure 
ATNSSGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREETKASGMKAT
CCCCCCCCCCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DGVPTPKDICEVLDDYVIGQATAKRVLSVAVHNHYKRLNHAQKAGNDIELSKSNILLIGP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEEC
TGCGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQASEYNVERAQRGI
CCCCHHHHHHHHHHHHCCCCHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHCCC
VYIDEVDKITRKSENPSITRDVSGEGVQQALLKLMEGTVASVPPQGGRKHPQQEFLQVDT
EEEEHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCHHCCCCCCCCCCCHHHHHHHCC
TNILFICGGAFAGLDKIIKQRGKGSAMGFGADVREESDAGVGETFRDLEPEDLLKFGLIP
CCEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHCCCH
EFVGRLPVLATLEDLDEDALITILTKPKNALVKQYQRLFELEDTELDFTDEALSAIAKKA
HHHCCCCHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
IERKTGARGLRSILEDILLDTMFELPGMESVTKVVVNEEAVCSEAQPLMIHADEKESATA
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHCCCCCEEEECCCCCCCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA