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The map label for this gene is dgoR [H]

Identifier: 99081288

GI number: 99081288

Start: 1545359

End: 1546090

Strand: Direct

Name: dgoR [H]

Synonym: TM1040_1447

Alternate gene names: 99081288

Gene position: 1545359-1546090 (Clockwise)

Preceding gene: 99081274

Following gene: 99081289

Centisome position: 48.28

GC content: 63.25

Gene sequence:

>732_bases
GTGAAGATCGATCCCAAAAGCAGCGCTGATCTCTCCGCTCAGATTGCCACTGCAATCCGCGACGCCATCATCTCTGGCGC
ACTGATTGTCGACGAACGCCTGCCCTCGGAGGCCGAACTGGCCGAGCAGTTCCAGGTTTCCCGCGCCACCGTGCGCGAAG
GGTTGAAGAGGCTCGCAGCGCAATCGCTGATCCGCACACAACGCGGCGCGTCTGGCGGGGCTTTTGTGAATCGGCTGAGT
TTTGAGGATGCTTACAGCCAGCAGATCACCACCTCGACCCTTCTGCTCAGCATGAATGCGGTGAGTTTCGATACGGCCTG
CGAAGCGCGCTATGCGCTGGAGCGGGCCTGCGCGCCGCTTTCTGCAGAGCGTCGCACCGCCGACCAGCTGGCCACCATGC
GCGCCGAGATCTTTCGACAGGGTCAGCCCGGCCTCACGGATGAGGCCTTTTGCGCGTCTGACGTGGCCTTTCACCGCGCT
CTGGTGGATGGCGCGCATAATCCGGTCCTGTCCTACCAGCTTGCCGGTGCCGTCGAGGCGATGCAGCCCCTCATGAACAT
GATCACCTTCACCGCAAGAGACCGCGCCACCATTCTTGCGCTGCACACCACCGTCGCCGATGCCATCGAAGCCGGCAAGG
GAGACGCGGCAGTCGCGGGTCTCAGCGCATTAGAGGAGGAAACGCGCAACCTCGCCGCCGATGTCTTTGCCCGCCGCGCG
ACAAAACGCTGA

Upstream 100 bases:

>100_bases
TCGCTGCGACTCATTCCCTCTTGTGAATCAAATGTCAGACTTTTAAATGTCTGACAAATGAAAATTTTCACCCCCCAATC
TGACGTGAGGGCACATACTC

Downstream 100 bases:

>100_bases
CCCTCTTCATCTTCTTTCAAATATCCCCGCCGGAGGCAACGCGCGTCAGCACGTCAATTCTCCCCTTTAACTCCCCTCCA
AACCACCCTATATTTGGAGT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MKIDPKSSADLSAQIATAIRDAIISGALIVDERLPSEAELAEQFQVSRATVREGLKRLAAQSLIRTQRGASGGAFVNRLS
FEDAYSQQITTSTLLLSMNAVSFDTACEARYALERACAPLSAERRTADQLATMRAEIFRQGQPGLTDEAFCASDVAFHRA
LVDGAHNPVLSYQLAGAVEAMQPLMNMITFTARDRATILALHTTVADAIEAGKGDAAVAGLSALEEETRNLAADVFARRA
TKR

Sequences:

>Translated_243_residues
MKIDPKSSADLSAQIATAIRDAIISGALIVDERLPSEAELAEQFQVSRATVREGLKRLAAQSLIRTQRGASGGAFVNRLS
FEDAYSQQITTSTLLLSMNAVSFDTACEARYALERACAPLSAERRTADQLATMRAEIFRQGQPGLTDEAFCASDVAFHRA
LVDGAHNPVLSYQLAGAVEAMQPLMNMITFTARDRATILALHTTVADAIEAGKGDAAVAGLSALEEETRNLAADVFARRA
TKR
>Mature_243_residues
MKIDPKSSADLSAQIATAIRDAIISGALIVDERLPSEAELAEQFQVSRATVREGLKRLAAQSLIRTQRGASGGAFVNRLS
FEDAYSQQITTSTLLLSMNAVSFDTACEARYALERACAPLSAERRTADQLATMRAEIFRQGQPGLTDEAFCASDVAFHRA
LVDGAHNPVLSYQLAGAVEAMQPLMNMITFTARDRATILALHTTVADAIEAGKGDAAVAGLSALEEETRNLAADVFARRA
TKR

Specific function: Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994955, Length=225, Percent_Identity=31.1111111111111, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790032, Length=226, Percent_Identity=30.5309734513274, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786303, Length=218, Percent_Identity=31.1926605504587, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26046; Mature: 26046

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIDPKSSADLSAQIATAIRDAIISGALIVDERLPSEAELAEQFQVSRATVREGLKRLAA
CCCCCCCCCHHHHHHHHHHHHHHHHCHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QSLIRTQRGASGGAFVNRLSFEDAYSQQITTSTLLLSMNAVSFDTACEARYALERACAPL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
SAERRTADQLATMRAEIFRQGQPGLTDEAFCASDVAFHRALVDGAHNPVLSYQLAGAVEA
CHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
MQPLMNMITFTARDRATILALHTTVADAIEAGKGDAAVAGLSALEEETRNLAADVFARRA
HHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TKR
CCC
>Mature Secondary Structure
MKIDPKSSADLSAQIATAIRDAIISGALIVDERLPSEAELAEQFQVSRATVREGLKRLAA
CCCCCCCCCHHHHHHHHHHHHHHHHCHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QSLIRTQRGASGGAFVNRLSFEDAYSQQITTSTLLLSMNAVSFDTACEARYALERACAPL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
SAERRTADQLATMRAEIFRQGQPGLTDEAFCASDVAFHRALVDGAHNPVLSYQLAGAVEA
CHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
MQPLMNMITFTARDRATILALHTTVADAIEAGKGDAAVAGLSALEEETRNLAADVFARRA
HHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TKR
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]