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The map label for this gene is ntrY [H]

Identifier: 99081201

GI number: 99081201

Start: 1452860

End: 1455139

Strand: Reverse

Name: ntrY [H]

Synonym: TM1040_1360

Alternate gene names: 99081201

Gene position: 1455139-1452860 (Counterclockwise)

Preceding gene: 99081202

Following gene: 99081200

Centisome position: 45.46

GC content: 58.51

Gene sequence:

>2280_bases
GTGGCACAGTTGTCACATATCCGTTCGGTGTATCTGTGGCTTGGCGCCCTGGATCGCTGGCGTAAGACGCGCCGCGCGCG
CAACATCACCACCTTGGGGCTGGTGTTGCTCGGGCCCATCATGGCTTTGGTGACATTTCTTGTGATCGGTCCCTTTGGCC
AGAATGCGAGCTCCCCGGCGCTGCGCCTGATCCTGCTCGCTGATCTTGTCTATGTGCTGTCGATTGCAGCGCTGGTCCTC
AGCCAGATCGGACGTCTGATCGCCGCGCGGCGTGAGAAGTCGGCGGGCTCGCGTCTGCACCTGCGATTGATCGGCGCCTT
TGCCTTCCTCGCGCTGGTGCCCACCGTGACGGTTGCGGTCTTTGCTGTCTTGACGGTGAATGTGGGTCTTGAGGGCTGGT
TTTCCGAGCGCGTGCGCGATGTGATTGGCAACTCGGTCAAGGCTGCAGAAGCCTATGAACGCCAGCAGCGTCAGGATCTC
GAACAGGATGCGCTGGCGCTGGCGCGTTTTCTGGATCGAAGCCGGAACAAGAATTTCTTCATGAGCGACGGGCAGTTGCG
GCAGGTTCTGTCGCAAGGCCAGCTGCAGATCCAGCGCGGCCTGCAAGAGGCCTATGTGATCAATGGGATCGGGGCGATCC
AAACCCGCGGGGAGCGATCCTACGAGTTTGACTTCGAAGAACCCACTGATGCACAGATCGCAGCCGCCGAATCCGAGGGG
CTGCACCTGATCCAGGATTGGGACAATAGCGAGTTTCGCGCCCTGGTGCGTCTCAACGCCTTTGTGGATCGGTATCTCTA
CGTCAGTCGTGAAGTCGACGGTGAACTGTTGAACCTGCTCGACGACACTCAGGAAACTGCGCATCTTTATCAACAACTCG
AGAGTGAGCGCGGGCGGGTGCTATTTGAATTCGGCCTGTTGTATCTCGGCTTTGCAGTGATCCTGATCCTTGCGGCGATG
TGGCTTGGCATGTGGTTTGCGGAGCGCCTTTCACGCCCGGTCGGGCGCTTGACGGTTGCGGCGCAGCGTGTGGGCGGTGG
CAATCTGAGTGTGCAGGTGGTAGAAGAGAACGGCGACGACGAAATTGCGCAATTAGGGCGTTATTTCAATCAGATGACGC
AGCAACTTCAGGCACAACGTGAAACCTTGCTACAGAACACGCATCAGATCGAGCAGCGCCGTCGTCTGTTTGACTCGGTG
CTGTCGTCGGTGACCTCTGGCGTTGTGGGGCTTGATGCAAAGGGCTGCGTGACCTTTGTGAACACCTCGGCCAAGCGCTT
GCTGGATTGGCGTGAGGACCAAAAGTCACTTGCACTTGCGGTGGCCATTCCGGAGTTTGGTCCGCTGTTTGACGATCTCG
TCAAAGGCGGCAGCAACAATGCCCAGGGTGAGATCAAAGTAACCCGACAAGGGCAGTTGGAGAACCTCCTTGTGCGGATG
TCGCGCCGACACGGCGATGACAATACGCTCGAGGGCTATGTGGTTGCCTTTGACGATGTCACCGATCTCGTGAGTGCGCA
GCGCATGGCGGCATGGGGTGACGTGGCGCGCCGGATCGCCCATGAGATCAAGAACCCGCTCACCCCGATCCAGCTCAGCG
CGGAGCGGATCAAGCGCAAGTTTGCTCCAAAACTCAGCGAAGAGCAGAGCGATCAACTGCAGTCGATGACCGATGTTATT
GTGCGTCAAACCAACGACTTGCGTCGCATCGTTGATGAGTTTTCAAAATTTGCACGGATGCCGGAACCCGATCGACACGA
AGAAGACCTAGGCGCGCTGGTGCATAGTGCCGTGTTGCTGCAGCAAGCCGGGCAACCTGATCTCAAGATCCACGCGCAGA
TCCCGGATCATCCGCTGAACGTGGATGTTGACGCCACAATGATCGGGCAGGCGCTGACCAATCTTATCAAGAACGCTGGC
GAAGCCACGGAGACCTTGCGCAAGAAAGGCGTAGAGCCGGGCTACGCGCCGGAGATCCGGGTCGATGTGAGCAGCGATGA
TAGCGGGTTTGTCATTACGATTGCGGACAATGGGATCGGCTTGCCCGCAGATCGCGCCCGGCTGTTTGAACCCTATGTCA
CCACCCGTGACGAGGGCACAGGCCTCGGCCTGCCGATCGTAAAGAAAATTATCGAAGAGCATGGTGGCAGTTTGGTGCTG
GAAGACGCGCCCATCTTTGACGGGATGAGCCACCAAGGCGCAATGGCGGTGATCCGTCTCCCGGCGCTGGCGCCAGGAAA
TGCCGTCCAGAAACAAACTATAGTAGCAGGGCTGACATGA

Upstream 100 bases:

>100_bases
ATATCGCCACAGCAGCGTTGCCCGGAGGTCAATAGGCCCATGGGGCAACGCGAGATAGTGTGGTGAGCCAAGAAGGCTCA
ACATCAACTGGGGGCAGGCG

Downstream 100 bases:

>100_bases
GTGATATTCTGATTGTTGATGATGAACGTGACATCCGGGAGCTGGTTTCAGACATCCTGGAGGACGAAAGCTATGCCACG
CGCAAAGCGGCCAACTCCGA

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 759; Mature: 758

Protein sequence:

>759_residues
MAQLSHIRSVYLWLGALDRWRKTRRARNITTLGLVLLGPIMALVTFLVIGPFGQNASSPALRLILLADLVYVLSIAALVL
SQIGRLIAARREKSAGSRLHLRLIGAFAFLALVPTVTVAVFAVLTVNVGLEGWFSERVRDVIGNSVKAAEAYERQQRQDL
EQDALALARFLDRSRNKNFFMSDGQLRQVLSQGQLQIQRGLQEAYVINGIGAIQTRGERSYEFDFEEPTDAQIAAAESEG
LHLIQDWDNSEFRALVRLNAFVDRYLYVSREVDGELLNLLDDTQETAHLYQQLESERGRVLFEFGLLYLGFAVILILAAM
WLGMWFAERLSRPVGRLTVAAQRVGGGNLSVQVVEENGDDEIAQLGRYFNQMTQQLQAQRETLLQNTHQIEQRRRLFDSV
LSSVTSGVVGLDAKGCVTFVNTSAKRLLDWREDQKSLALAVAIPEFGPLFDDLVKGGSNNAQGEIKVTRQGQLENLLVRM
SRRHGDDNTLEGYVVAFDDVTDLVSAQRMAAWGDVARRIAHEIKNPLTPIQLSAERIKRKFAPKLSEEQSDQLQSMTDVI
VRQTNDLRRIVDEFSKFARMPEPDRHEEDLGALVHSAVLLQQAGQPDLKIHAQIPDHPLNVDVDATMIGQALTNLIKNAG
EATETLRKKGVEPGYAPEIRVDVSSDDSGFVITIADNGIGLPADRARLFEPYVTTRDEGTGLGLPIVKKIIEEHGGSLVL
EDAPIFDGMSHQGAMAVIRLPALAPGNAVQKQTIVAGLT

Sequences:

>Translated_759_residues
MAQLSHIRSVYLWLGALDRWRKTRRARNITTLGLVLLGPIMALVTFLVIGPFGQNASSPALRLILLADLVYVLSIAALVL
SQIGRLIAARREKSAGSRLHLRLIGAFAFLALVPTVTVAVFAVLTVNVGLEGWFSERVRDVIGNSVKAAEAYERQQRQDL
EQDALALARFLDRSRNKNFFMSDGQLRQVLSQGQLQIQRGLQEAYVINGIGAIQTRGERSYEFDFEEPTDAQIAAAESEG
LHLIQDWDNSEFRALVRLNAFVDRYLYVSREVDGELLNLLDDTQETAHLYQQLESERGRVLFEFGLLYLGFAVILILAAM
WLGMWFAERLSRPVGRLTVAAQRVGGGNLSVQVVEENGDDEIAQLGRYFNQMTQQLQAQRETLLQNTHQIEQRRRLFDSV
LSSVTSGVVGLDAKGCVTFVNTSAKRLLDWREDQKSLALAVAIPEFGPLFDDLVKGGSNNAQGEIKVTRQGQLENLLVRM
SRRHGDDNTLEGYVVAFDDVTDLVSAQRMAAWGDVARRIAHEIKNPLTPIQLSAERIKRKFAPKLSEEQSDQLQSMTDVI
VRQTNDLRRIVDEFSKFARMPEPDRHEEDLGALVHSAVLLQQAGQPDLKIHAQIPDHPLNVDVDATMIGQALTNLIKNAG
EATETLRKKGVEPGYAPEIRVDVSSDDSGFVITIADNGIGLPADRARLFEPYVTTRDEGTGLGLPIVKKIIEEHGGSLVL
EDAPIFDGMSHQGAMAVIRLPALAPGNAVQKQTIVAGLT
>Mature_758_residues
AQLSHIRSVYLWLGALDRWRKTRRARNITTLGLVLLGPIMALVTFLVIGPFGQNASSPALRLILLADLVYVLSIAALVLS
QIGRLIAARREKSAGSRLHLRLIGAFAFLALVPTVTVAVFAVLTVNVGLEGWFSERVRDVIGNSVKAAEAYERQQRQDLE
QDALALARFLDRSRNKNFFMSDGQLRQVLSQGQLQIQRGLQEAYVINGIGAIQTRGERSYEFDFEEPTDAQIAAAESEGL
HLIQDWDNSEFRALVRLNAFVDRYLYVSREVDGELLNLLDDTQETAHLYQQLESERGRVLFEFGLLYLGFAVILILAAMW
LGMWFAERLSRPVGRLTVAAQRVGGGNLSVQVVEENGDDEIAQLGRYFNQMTQQLQAQRETLLQNTHQIEQRRRLFDSVL
SSVTSGVVGLDAKGCVTFVNTSAKRLLDWREDQKSLALAVAIPEFGPLFDDLVKGGSNNAQGEIKVTRQGQLENLLVRMS
RRHGDDNTLEGYVVAFDDVTDLVSAQRMAAWGDVARRIAHEIKNPLTPIQLSAERIKRKFAPKLSEEQSDQLQSMTDVIV
RQTNDLRRIVDEFSKFARMPEPDRHEEDLGALVHSAVLLQQAGQPDLKIHAQIPDHPLNVDVDATMIGQALTNLIKNAGE
ATETLRKKGVEPGYAPEIRVDVSSDDSGFVITIADNGIGLPADRARLFEPYVTTRDEGTGLGLPIVKKIIEEHGGSLVLE
DAPIFDGMSHQGAMAVIRLPALAPGNAVQKQTIVAGLT

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=403, Percent_Identity=26.302729528536, Blast_Score=116, Evalue=6e-27,
Organism=Escherichia coli, GI1790436, Length=215, Percent_Identity=30.2325581395349, Blast_Score=91, Evalue=4e-19,
Organism=Escherichia coli, GI1790567, Length=348, Percent_Identity=25.5747126436782, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1790346, Length=214, Percent_Identity=27.5700934579439, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 84086; Mature: 83955

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQLSHIRSVYLWLGALDRWRKTRRARNITTLGLVLLGPIMALVTFLVIGPFGQNASSPA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
LRLILLADLVYVLSIAALVLSQIGRLIAARREKSAGSRLHLRLIGAFAFLALVPTVTVAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHH
FAVLTVNVGLEGWFSERVRDVIGNSVKAAEAYERQQRQDLEQDALALARFLDRSRNKNFF
HHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
MSDGQLRQVLSQGQLQIQRGLQEAYVINGIGAIQTRGERSYEFDFEEPTDAQIAAAESEG
ECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCEECCCCCCCCCEEEECCCCC
LHLIQDWDNSEFRALVRLNAFVDRYLYVSREVDGELLNLLDDTQETAHLYQQLESERGRV
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHHHHHHHHHCCCE
LFEFGLLYLGFAVILILAAMWLGMWFAERLSRPVGRLTVAAQRVGGGNLSVQVVEENGDD
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEECCCCH
EIAQLGRYFNQMTQQLQAQRETLLQNTHQIEQRRRLFDSVLSSVTSGVVGLDAKGCVTFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEH
NTSAKRLLDWREDQKSLALAVAIPEFGPLFDDLVKGGSNNAQGEIKVTRQGQLENLLVRM
HHHHHHHHHHHHCHHHEEEEEECCCCCHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHH
SRRHGDDNTLEGYVVAFDDVTDLVSAQRMAAWGDVARRIAHEIKNPLTPIQLSAERIKRK
HHHCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
FAPKLSEEQSDQLQSMTDVIVRQTNDLRRIVDEFSKFARMPEPDRHEEDLGALVHSAVLL
HCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
QQAGQPDLKIHAQIPDHPLNVDVDATMIGQALTNLIKNAGEATETLRKKGVEPGYAPEIR
HHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEE
VDVSSDDSGFVITIADNGIGLPADRARLFEPYVTTRDEGTGLGLPIVKKIIEEHGGSLVL
EEECCCCCCEEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEE
EDAPIFDGMSHQGAMAVIRLPALAPGNAVQKQTIVAGLT
ECCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCC
>Mature Secondary Structure 
AQLSHIRSVYLWLGALDRWRKTRRARNITTLGLVLLGPIMALVTFLVIGPFGQNASSPA
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
LRLILLADLVYVLSIAALVLSQIGRLIAARREKSAGSRLHLRLIGAFAFLALVPTVTVAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHH
FAVLTVNVGLEGWFSERVRDVIGNSVKAAEAYERQQRQDLEQDALALARFLDRSRNKNFF
HHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
MSDGQLRQVLSQGQLQIQRGLQEAYVINGIGAIQTRGERSYEFDFEEPTDAQIAAAESEG
ECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCEECCCCCCCCCEEEECCCCC
LHLIQDWDNSEFRALVRLNAFVDRYLYVSREVDGELLNLLDDTQETAHLYQQLESERGRV
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHHHHHHHHHCCCE
LFEFGLLYLGFAVILILAAMWLGMWFAERLSRPVGRLTVAAQRVGGGNLSVQVVEENGDD
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEECCCCH
EIAQLGRYFNQMTQQLQAQRETLLQNTHQIEQRRRLFDSVLSSVTSGVVGLDAKGCVTFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEH
NTSAKRLLDWREDQKSLALAVAIPEFGPLFDDLVKGGSNNAQGEIKVTRQGQLENLLVRM
HHHHHHHHHHHHCHHHEEEEEECCCCCHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHH
SRRHGDDNTLEGYVVAFDDVTDLVSAQRMAAWGDVARRIAHEIKNPLTPIQLSAERIKRK
HHHCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
FAPKLSEEQSDQLQSMTDVIVRQTNDLRRIVDEFSKFARMPEPDRHEEDLGALVHSAVLL
HCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
QQAGQPDLKIHAQIPDHPLNVDVDATMIGQALTNLIKNAGEATETLRKKGVEPGYAPEIR
HHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEE
VDVSSDDSGFVITIADNGIGLPADRARLFEPYVTTRDEGTGLGLPIVKKIIEEHGGSLVL
EEECCCCCCEEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEE
EDAPIFDGMSHQGAMAVIRLPALAPGNAVQKQTIVAGLT
ECCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]