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The map label for this gene is sufC [H]

Identifier: 99081086

GI number: 99081086

Start: 1339654

End: 1340409

Strand: Direct

Name: sufC [H]

Synonym: TM1040_1245

Alternate gene names: 99081086

Gene position: 1339654-1340409 (Clockwise)

Preceding gene: 99081085

Following gene: 99081087

Centisome position: 41.85

GC content: 58.47

Gene sequence:

>756_bases
ATGCTAGAAATCAAAAACCTGCACGTGAAACTTGAGGATGAAGACAAGCAAATCCTCAAAGGTGTGAACCTCACCGTCGA
AGCTGGCAAAGTGCATGCGATCATGGGGCCGAACGGCTCAGGCAAATCGACGCTGTCCTATGTGCTGTCCGGCAAGGACG
GCTATGAAGTCACTGAGGGCTCCGCATCCCTGTTGGGTGAAGAACTCCTGGAGCTAGAGCCCGAAGAGCGCGCAGCGCTT
GGCGTGTTCCTCGCGTTCCAATACCCGGTCGAGATCCCCGGCGTGGGCAACATGACCTTCCTGCGGACTGCGGTGAATGC
GCAGCGCAAGGCGCGTGGCGAAGAGGAACTCTCAGCGACCGACTTCCTGAAGCACGTGCGCGCGCAGGCCAAAGAGTTGA
AGATCGACGCCGACATGCTGAAGCGCCCGGTCAATGTCGGCTTCTCCGGCGGTGAGAAGAAGCGCAACGAAATCCTGCAG
ATGGCGATGCTTGAGCCCAAGATGTGCATCCTCGACGAGACCGACTCCGGTCTTGACGTGGACGCGATGAAACTGGTCGC
GGACGGCGTCAACGCGCTGCGTGACGAAGGCCGCGGCTTCCTCGTTATCACCCACTACCAGCGTCTTCTGGATCACATCA
AACCGGATGTGGTGCACATCATGGCGGATGGTCGCATCGTTAAAACCGGTGGTCCCGAGCTGGCGCTTGAGGTCGAAAAC
AACGGTTACGCAGACATCCTGTCCGAGGTGGCATAA

Upstream 100 bases:

>100_bases
ACGTCATCAAGCCGCTTCAGTTGGATGCGGAGAGCTGACGAAACCACGATCTGCAGATCGCGCAGCCAGCGCTGACTGCA
AGCAGAAAAAGGCGAAAAAC

Downstream 100 bases:

>100_bases
TGGGACTTCCCGAGCTGAAACAAACAACGACGGAGGCACGCCTGGCGGCGTTGTCCTTGCCCGAAGGTGGATGTCTTGAG
GCGGCGCGTCGCGCCGCCGT

Product: FeS assembly ATPase SufC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MLEIKNLHVKLEDEDKQILKGVNLTVEAGKVHAIMGPNGSGKSTLSYVLSGKDGYEVTEGSASLLGEELLELEPEERAAL
GVFLAFQYPVEIPGVGNMTFLRTAVNAQRKARGEEELSATDFLKHVRAQAKELKIDADMLKRPVNVGFSGGEKKRNEILQ
MAMLEPKMCILDETDSGLDVDAMKLVADGVNALRDEGRGFLVITHYQRLLDHIKPDVVHIMADGRIVKTGGPELALEVEN
NGYADILSEVA

Sequences:

>Translated_251_residues
MLEIKNLHVKLEDEDKQILKGVNLTVEAGKVHAIMGPNGSGKSTLSYVLSGKDGYEVTEGSASLLGEELLELEPEERAAL
GVFLAFQYPVEIPGVGNMTFLRTAVNAQRKARGEEELSATDFLKHVRAQAKELKIDADMLKRPVNVGFSGGEKKRNEILQ
MAMLEPKMCILDETDSGLDVDAMKLVADGVNALRDEGRGFLVITHYQRLLDHIKPDVVHIMADGRIVKTGGPELALEVEN
NGYADILSEVA
>Mature_251_residues
MLEIKNLHVKLEDEDKQILKGVNLTVEAGKVHAIMGPNGSGKSTLSYVLSGKDGYEVTEGSASLLGEELLELEPEERAAL
GVFLAFQYPVEIPGVGNMTFLRTAVNAQRKARGEEELSATDFLKHVRAQAKELKIDADMLKRPVNVGFSGGEKKRNEILQ
MAMLEPKMCILDETDSGLDVDAMKLVADGVNALRDEGRGFLVITHYQRLLDHIKPDVVHIMADGRIVKTGGPELALEVEN
NGYADILSEVA

Specific function: Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May f

COG id: COG0396

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, ATPase component

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI42741659, Length=233, Percent_Identity=30.4721030042918, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI9961252, Length=233, Percent_Identity=29.1845493562232, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI9961250, Length=233, Percent_Identity=29.1845493562232, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI4505771, Length=233, Percent_Identity=29.1845493562232, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI21536378, Length=229, Percent_Identity=27.0742358078603, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1787972, Length=244, Percent_Identity=60.2459016393443, Blast_Score=304, Evalue=4e-84,
Organism=Escherichia coli, GI1790525, Length=218, Percent_Identity=31.651376146789, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789672, Length=242, Percent_Identity=26.8595041322314, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1786319, Length=193, Percent_Identity=31.0880829015544, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787500, Length=244, Percent_Identity=28.6885245901639, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789891, Length=230, Percent_Identity=28.695652173913, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787370, Length=238, Percent_Identity=25.2100840336134, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789593, Length=227, Percent_Identity=25.9911894273128, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787792, Length=216, Percent_Identity=26.8518518518519, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787029, Length=243, Percent_Identity=26.3374485596708, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787759, Length=252, Percent_Identity=27.3809523809524, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI71992290, Length=252, Percent_Identity=28.968253968254, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI212646699, Length=233, Percent_Identity=27.0386266094421, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115533592, Length=225, Percent_Identity=28, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193209708, Length=239, Percent_Identity=28.4518828451883, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI85726357, Length=218, Percent_Identity=28.4403669724771, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010230 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27424; Mature: 27424

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEIKNLHVKLEDEDKQILKGVNLTVEAGKVHAIMGPNGSGKSTLSYVLSGKDGYEVTEG
CCEEEEEEEEECCCHHHHHCCCCEEEECCEEEEEECCCCCCCCEEEEEEECCCCCEECCC
SASLLGEELLELEPEERAALGVFLAFQYPVEIPGVGNMTFLRTAVNAQRKARGEEELSAT
HHHHHHHHHHHCCCCHHHHEEEEEEEECCEECCCCCCHHHHHHHHHHHHHHCCHHHHHHH
DFLKHVRAQAKELKIDADMLKRPVNVGFSGGEKKRNEILQMAMLEPKMCILDETDSGLDV
HHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCH
DAMKLVADGVNALRDEGRGFLVITHYQRLLDHIKPDVVHIMADGRIVKTGGPELALEVEN
HHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCCCEEEEEECCEEEECCCCEEEEEECC
NGYADILSEVA
CCHHHHHHHCC
>Mature Secondary Structure
MLEIKNLHVKLEDEDKQILKGVNLTVEAGKVHAIMGPNGSGKSTLSYVLSGKDGYEVTEG
CCEEEEEEEEECCCHHHHHCCCCEEEECCEEEEEECCCCCCCCEEEEEEECCCCCEECCC
SASLLGEELLELEPEERAALGVFLAFQYPVEIPGVGNMTFLRTAVNAQRKARGEEELSAT
HHHHHHHHHHHCCCCHHHHEEEEEEEECCEECCCCCCHHHHHHHHHHHHHHCCHHHHHHH
DFLKHVRAQAKELKIDADMLKRPVNVGFSGGEKKRNEILQMAMLEPKMCILDETDSGLDV
HHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCH
DAMKLVADGVNALRDEGRGFLVITHYQRLLDHIKPDVVHIMADGRIVKTGGPELALEVEN
HHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCCCEEEEEECCEEEECCCCEEEEEECC
NGYADILSEVA
CCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]