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The map label for this gene is iscR [H]

Identifier: 99081081

GI number: 99081081

Start: 1335357

End: 1335815

Strand: Direct

Name: iscR [H]

Synonym: TM1040_1240

Alternate gene names: 99081081

Gene position: 1335357-1335815 (Clockwise)

Preceding gene: 99081075

Following gene: 99081082

Centisome position: 41.72

GC content: 59.69

Gene sequence:

>459_bases
ATGAAGCTTTCGACAAAAGGACGGTACGCAATGGTGGCCTTGGCTGACATCGCGTTGCAGCCATCAGAGGGACTGGTCGT
CCTGGCCGATATCTCCAAGCGTCAGCAGATCTCTTTGCCGTATCTCGAGCAGCTCTTCGTGAAACTACGTCGTGGCGGGC
TTGTGGCCTCCGTGCGTGGGCCCGGGGGTGGGTATCGTCTGGCGCGGCCCGCATCCGAAATTCGGGTCGTTGAGATCCTC
GCCGCCGTTGATGAGACCGTAGACGCCATGCACAAGGGGGCAGGGGCGTCGGGTGGATCAAGTGGGAGCAGGGCGCAATC
ACTGACCAACCGTCTGTGGGAGGGGCTGAGTGCGCATGTCTACGTCTTTCTTCATCAAACACGCCTTTCGGATGTGATCG
AGAACGACCTCGCGCCCTGTCCAGCAGTGCCCAATCTCTTCTCCGTGGTCGATGAATAG

Upstream 100 bases:

>100_bases
AAGAGGCGCAGGTGAAGGACCGGCACCCTGTCAAGCTGAGATACGCATTGGCAGGGCTATCGTCAATCATTTGCTGCTTT
TTCGACAAAAGGGTTGGCAG

Downstream 100 bases:

>100_bases
ACCACGCGCGAGGCCCCCCTTGACCTCTGCGTGAATGCAACTGTGACTGCCTGAAAATATGACTCCATGACTCGTGTTTA
TTTAGATCATAACGCCACAT

Product: BadM/Rrf2 family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MKLSTKGRYAMVALADIALQPSEGLVVLADISKRQQISLPYLEQLFVKLRRGGLVASVRGPGGGYRLARPASEIRVVEIL
AAVDETVDAMHKGAGASGGSSGSRAQSLTNRLWEGLSAHVYVFLHQTRLSDVIENDLAPCPAVPNLFSVVDE

Sequences:

>Translated_152_residues
MKLSTKGRYAMVALADIALQPSEGLVVLADISKRQQISLPYLEQLFVKLRRGGLVASVRGPGGGYRLARPASEIRVVEIL
AAVDETVDAMHKGAGASGGSSGSRAQSLTNRLWEGLSAHVYVFLHQTRLSDVIENDLAPCPAVPNLFSVVDE
>Mature_152_residues
MKLSTKGRYAMVALADIALQPSEGLVVLADISKRQQISLPYLEQLFVKLRRGGLVASVRGPGGGYRLARPASEIRVVEIL
AAVDETVDAMHKGAGASGGSSGSRAQSLTNRLWEGLSAHVYVFLHQTRLSDVIENDLAPCPAVPNLFSVVDE

Specific function: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins [H]

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=135, Percent_Identity=48.8888888888889, Blast_Score=122, Evalue=1e-29,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010242
- InterPro:   IPR000944
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 16241; Mature: 16241

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS01332 UPF0074

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSTKGRYAMVALADIALQPSEGLVVLADISKRQQISLPYLEQLFVKLRRGGLVASVRG
CCCCCCCCEEEEEEEHHEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEEEC
PGGGYRLARPASEIRVVEILAAVDETVDAMHKGAGASGGSSGSRAQSLTNRLWEGLSAHV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEE
YVFLHQTRLSDVIENDLAPCPAVPNLFSVVDE
EEEEEHHHHHHHHHHCCCCCCCCCHHHHHHCC
>Mature Secondary Structure
MKLSTKGRYAMVALADIALQPSEGLVVLADISKRQQISLPYLEQLFVKLRRGGLVASVRG
CCCCCCCCEEEEEEEHHEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEEEC
PGGGYRLARPASEIRVVEILAAVDETVDAMHKGAGASGGSSGSRAQSLTNRLWEGLSAHV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEE
YVFLHQTRLSDVIENDLAPCPAVPNLFSVVDE
EEEEEHHHHHHHHHHCCCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA