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The map label for this gene is moaC [H]

Identifier: 99080978

GI number: 99080978

Start: 1223982

End: 1224452

Strand: Reverse

Name: moaC [H]

Synonym: TM1040_1137

Alternate gene names: 99080978

Gene position: 1224452-1223982 (Counterclockwise)

Preceding gene: 99080979

Following gene: 99080977

Centisome position: 38.25

GC content: 61.78

Gene sequence:

>471_bases
ATGTCGCTCACACATTTTGACCAGAAGGGCGATGCCCATATGGTCGACGTCTCCGAAAAGGCCGTGACCGCGCGCATTGC
CGTGGCCGAGGGCCATATCAAGATGGCGCAAGATACCTTTGACGTGATCAGCGAAGGTCGCGCCAAGAAAGGCGATGTTC
TCTCTGTGGCGCGCCTTGCCGGAATCATGGGCGCCAAGAAAACCGCCGAACTGATCCCGCTCTGCCACCCGCTGCCGATC
ACCAAGGTCGCCGTGGACCTGACGCTCGACCCCGATCTGCCCGGCGTGCGCGTTGAGGGCACCGTCAAGACCACCGGCCA
GACCGGCGTCGAAATGGAAGCGCTCACAGCGGTCTCCACGGCCTGCCTCACCGTCTATGACATGGCCAAAGCCGTTGATA
AGGCGATGGAAATCGGAGGCGTCCGGGTCCTGCTCAAAGACGGCGGCAAATCCGGTCGGTATGAGGCGTGA

Upstream 100 bases:

>100_bases
GTGACCGCCGCCACCCGCGCGATCCTTGCAAACCCGCTGACCCCCTCGCTCTGATCCAATCGAACTGACCCTTTTGATCT
GTCCACAGGAGAGACCGCCG

Downstream 100 bases:

>100_bases
TCCATGATCTCCGTCGCTGACGCCCGCGCCGCCCTTCTGGACCTTGTCGCGCCGCTCACGGTTGAAACCGTCCCACTGGC
AGAGGCCGCAGGGCGGGTGC

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MSLTHFDQKGDAHMVDVSEKAVTARIAVAEGHIKMAQDTFDVISEGRAKKGDVLSVARLAGIMGAKKTAELIPLCHPLPI
TKVAVDLTLDPDLPGVRVEGTVKTTGQTGVEMEALTAVSTACLTVYDMAKAVDKAMEIGGVRVLLKDGGKSGRYEA

Sequences:

>Translated_156_residues
MSLTHFDQKGDAHMVDVSEKAVTARIAVAEGHIKMAQDTFDVISEGRAKKGDVLSVARLAGIMGAKKTAELIPLCHPLPI
TKVAVDLTLDPDLPGVRVEGTVKTTGQTGVEMEALTAVSTACLTVYDMAKAVDKAMEIGGVRVLLKDGGKSGRYEA
>Mature_155_residues
SLTHFDQKGDAHMVDVSEKAVTARIAVAEGHIKMAQDTFDVISEGRAKKGDVLSVARLAGIMGAKKTAELIPLCHPLPIT
KVAVDLTLDPDLPGVRVEGTVKTTGQTGVEMEALTAVSTACLTVYDMAKAVDKAMEIGGVRVLLKDGGKSGRYEA

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=154, Percent_Identity=55.8441558441558, Blast_Score=168, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=46.3087248322148, Blast_Score=131, Evalue=1e-31,
Organism=Drosophila melanogaster, GI28574490, Length=149, Percent_Identity=54.3624161073826, Blast_Score=152, Evalue=1e-37,
Organism=Drosophila melanogaster, GI28574492, Length=137, Percent_Identity=54.7445255474453, Blast_Score=141, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 16419; Mature: 16288

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTHFDQKGDAHMVDVSEKAVTARIAVAEGHIKMAQDTFDVISEGRAKKGDVLSVARLA
CCCCCCCCCCCEEEEECCCCCEEEEEEEECCCEEEHHHHHHHHHCCCCCCCCHHHHHHHH
GIMGAKKTAELIPLCHPLPITKVAVDLTLDPDLPGVRVEGTVKTTGQTGVEMEALTAVST
HHHCCCCHHHHCCCCCCCCCCEEEEEEEECCCCCCEEEEEEEEECCCCCCCHHHHHHHHH
ACLTVYDMAKAVDKAMEIGGVRVLLKDGGKSGRYEA
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure 
SLTHFDQKGDAHMVDVSEKAVTARIAVAEGHIKMAQDTFDVISEGRAKKGDVLSVARLA
CCCCCCCCCCEEEEECCCCCEEEEEEEECCCEEEHHHHHHHHHCCCCCCCCHHHHHHHH
GIMGAKKTAELIPLCHPLPITKVAVDLTLDPDLPGVRVEGTVKTTGQTGVEMEALTAVST
HHHCCCCHHHHCCCCCCCCCCEEEEEEEECCCCCCEEEEEEEEECCCCCCCHHHHHHHHH
ACLTVYDMAKAVDKAMEIGGVRVLLKDGGKSGRYEA
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA