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The map label for this gene is yfkJ [H]

Identifier: 99080516

GI number: 99080516

Start: 721940

End: 722389

Strand: Direct

Name: yfkJ [H]

Synonym: TM1040_0675

Alternate gene names: 99080516

Gene position: 721940-722389 (Clockwise)

Preceding gene: 99080514

Following gene: 99080519

Centisome position: 22.55

GC content: 55.56

Gene sequence:

>450_bases
GTGGAAAGCGTATTGTTTGTTTGTCTTGGGAATATTTGTCGATCTCCTGCCGCGGAGGCGATATTTCGTGAAAGCTGTCC
CAATATCCAATGCGATAGCGCGGGGACAGCTGGCTACCATGTCGGCAGTCCTCCCTATCCAGAGATGGCAAAGGCCGCCC
GCGCGCGAGGAATTGACATGAGCGACTTGCGGGCACGGCAATTCTGCGCGGAGGATTTCCGGAACTTTGATTTGATCGTT
GTAATGGATCAGGACAATCAGGAAAACGTCGAGTCCCTGCGCCCCGCGGGAGACCGGACACCGGTAGTTTTATTTGCACC
GATGGCGGCGGGCTTTGATGTCGAGGCGGTACCGGATCCCTATTACACGCGGGACTTTGATGGATGCCTTGATCTGTTGG
AGAGCGCAGCACAAGGATTGAAGCGCTATGTCACTCAGGCCGGGGTGTGA

Upstream 100 bases:

>100_bases
CCTCTGGTTTCAAATTGGTTCCAGCATTGATGACCTGCGCTCTGGTGCCTATCAAAACTATATATATTATTTTGAAGTGC
CAAAAACAAAAGGGGGCTTC

Downstream 100 bases:

>100_bases
ACGGGGATCCCGGGCACGGGTATTGACGGCATAAAAGCCAAACTGGGCGCCATGTCGTATGCGGGAAATCGCAGTCTGGG
CGCGGGTGACGCGCCCAGGC

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: LMPTP [H]

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MESVLFVCLGNICRSPAAEAIFRESCPNIQCDSAGTAGYHVGSPPYPEMAKAARARGIDMSDLRARQFCAEDFRNFDLIV
VMDQDNQENVESLRPAGDRTPVVLFAPMAAGFDVEAVPDPYYTRDFDGCLDLLESAAQGLKRYVTQAGV

Sequences:

>Translated_149_residues
MESVLFVCLGNICRSPAAEAIFRESCPNIQCDSAGTAGYHVGSPPYPEMAKAARARGIDMSDLRARQFCAEDFRNFDLIV
VMDQDNQENVESLRPAGDRTPVVLFAPMAAGFDVEAVPDPYYTRDFDGCLDLLESAAQGLKRYVTQAGV
>Mature_149_residues
MESVLFVCLGNICRSPAAEAIFRESCPNIQCDSAGTAGYHVGSPPYPEMAKAARARGIDMSDLRARQFCAEDFRNFDLIV
VMDQDNQENVESLRPAGDRTPVVLFAPMAAGFDVEAVPDPYYTRDFDGCLDLLESAAQGLKRYVTQAGV

Specific function: Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=135, Percent_Identity=39.2592592592593, Blast_Score=88, Evalue=3e-18,
Organism=Homo sapiens, GI6005988, Length=135, Percent_Identity=36.2962962962963, Blast_Score=80, Evalue=5e-16,
Organism=Homo sapiens, GI96304457, Length=79, Percent_Identity=46.8354430379747, Blast_Score=67, Evalue=8e-12,
Organism=Escherichia coli, GI87081812, Length=138, Percent_Identity=33.3333333333333, Blast_Score=78, Evalue=2e-16,
Organism=Escherichia coli, GI1788375, Length=139, Percent_Identity=33.8129496402878, Blast_Score=67, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6325330, Length=136, Percent_Identity=33.0882352941176, Blast_Score=85, Evalue=4e-18,
Organism=Drosophila melanogaster, GI78706764, Length=131, Percent_Identity=32.0610687022901, Blast_Score=86, Evalue=7e-18,
Organism=Drosophila melanogaster, GI78706766, Length=133, Percent_Identity=31.5789473684211, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI78706768, Length=133, Percent_Identity=31.5789473684211, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI78711846, Length=153, Percent_Identity=32.6797385620915, Blast_Score=76, Evalue=9e-15,
Organism=Drosophila melanogaster, GI78706770, Length=126, Percent_Identity=34.1269841269841, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI78706772, Length=126, Percent_Identity=34.1269841269841, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 16275; Mature: 16275

Theoretical pI: Translated: 4.24; Mature: 4.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESVLFVCLGNICRSPAAEAIFRESCPNIQCDSAGTAGYHVGSPPYPEMAKAARARGIDM
CCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCH
SDLRARQFCAEDFRNFDLIVVMDQDNQENVESLRPAGDRTPVVLFAPMAAGFDVEAVPDP
HHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCC
YYTRDFDGCLDLLESAAQGLKRYVTQAGV
CCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MESVLFVCLGNICRSPAAEAIFRESCPNIQCDSAGTAGYHVGSPPYPEMAKAARARGIDM
CCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCH
SDLRARQFCAEDFRNFDLIVVMDQDNQENVESLRPAGDRTPVVLFAPMAAGFDVEAVPDP
HHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCC
YYTRDFDGCLDLLESAAQGLKRYVTQAGV
CCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]