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The map label for this gene is yajO [H]

Identifier: 99080332

GI number: 99080332

Start: 513650

End: 514654

Strand: Reverse

Name: yajO [H]

Synonym: TM1040_0491

Alternate gene names: 99080332

Gene position: 514654-513650 (Counterclockwise)

Preceding gene: 99080334

Following gene: 99080331

Centisome position: 16.08

GC content: 62.69

Gene sequence:

>1005_bases
ATGATCAGGCCAAACTCTGCGTTGCGCGCGCCCGGTCTGCGTGTCAGTCTCCGGCGCATGACTGCTCAGACTTGCCCCCC
GCTCACCACCCTTGATGGCCATGACGTTGGCCGGTTCGCCTTTGGCTGCATGCAATTTGGCGGACGCGCCGATGCGCAGG
CCTCTGCCGAAATGTATGAGGCCTGCCGCGCAGCAGGTCTGCGCCATTTTGATACCGCGTGGCTCTATACCGAGGGCGCC
AGCGAAGAGATCCTCGGTCAGTTGATCGCCAAGGACCGCGAGAGCCTCTATGTCGCGACCAAGGTTGGCTTCACCGGCGG
CGCCAGCGCGGCGAATATGCGAGCGCAGTTCGATCAGTGCCGACAGCGCCTGAAGCTCGATCAGGTGGATCTTCTGTATT
TGCACCGGTTTGACCCTGAAACCCCGCTCGAGGACACGCTGACCTGTTTTGCCGAACTTAAACAGGAAGGGCACATCCGC
CATGTTGGCCTGTCAAACTTCGCCGCCTGGCAGGTCATGAAAGCCGTTGCTCTCGCGGCGCGACTGGGCCTCCGGATTGA
CGTGCTACAGCCGATGTACTCGCTGGTGAAACGACAGGCCGAGGTGGAAATCCTGCCGATGTGTGCCGACCAGGGGATTT
TGCCCGTACCCTATTCGCCGCTGGGCGGCGGGCTCTTGACCGGGAAATATGCGCAAGGCGGCACAGGTCGGTTGAGCGAG
GATGAAAACTATCGTGCCCGCTATGGCCAGGATTGGATGCACCGGACAGCCTCCGATCTTCTGCACTTGGCCGAGGATCT
TGGCACCGATCCCGCGACGCTGGCAGTCGCATGGGCCGCAGGCCACCCCGCGCGCCCGGCTCCGATCCTCTCGGCACGTT
CCGCAACCCAGCTTGCGCCCTCGCTCAAGGCCACGGAATTTGACATGTCTCCAGAACTTTATGCGCGTATCGAAGCCCTG
AGCCCCCGCCCGGCCCCCGCCACGGACCGGCTCGAAGAAGCATGA

Upstream 100 bases:

>100_bases
GAAACGGGTCGATGAGGGGGCGGATCTTGGCATCAAACATGATCCAGATCTAACCGCTAGACGGTGAAACATCCACTCAC
GTTGCCGCTGCCGCGTCGTG

Downstream 100 bases:

>100_bases
TAGACACTCTGATCATCGGCGGCGGAGTGGCCGGGCTTGGTGCAGCGGCACATTTGTCGCCATCGCATCAGGTGGTGGTG
CTGGAACGCGAGGAGGTGCT

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MIRPNSALRAPGLRVSLRRMTAQTCPPLTTLDGHDVGRFAFGCMQFGGRADAQASAEMYEACRAAGLRHFDTAWLYTEGA
SEEILGQLIAKDRESLYVATKVGFTGGASAANMRAQFDQCRQRLKLDQVDLLYLHRFDPETPLEDTLTCFAELKQEGHIR
HVGLSNFAAWQVMKAVALAARLGLRIDVLQPMYSLVKRQAEVEILPMCADQGILPVPYSPLGGGLLTGKYAQGGTGRLSE
DENYRARYGQDWMHRTASDLLHLAEDLGTDPATLAVAWAAGHPARPAPILSARSATQLAPSLKATEFDMSPELYARIEAL
SPRPAPATDRLEEA

Sequences:

>Translated_334_residues
MIRPNSALRAPGLRVSLRRMTAQTCPPLTTLDGHDVGRFAFGCMQFGGRADAQASAEMYEACRAAGLRHFDTAWLYTEGA
SEEILGQLIAKDRESLYVATKVGFTGGASAANMRAQFDQCRQRLKLDQVDLLYLHRFDPETPLEDTLTCFAELKQEGHIR
HVGLSNFAAWQVMKAVALAARLGLRIDVLQPMYSLVKRQAEVEILPMCADQGILPVPYSPLGGGLLTGKYAQGGTGRLSE
DENYRARYGQDWMHRTASDLLHLAEDLGTDPATLAVAWAAGHPARPAPILSARSATQLAPSLKATEFDMSPELYARIEAL
SPRPAPATDRLEEA
>Mature_334_residues
MIRPNSALRAPGLRVSLRRMTAQTCPPLTTLDGHDVGRFAFGCMQFGGRADAQASAEMYEACRAAGLRHFDTAWLYTEGA
SEEILGQLIAKDRESLYVATKVGFTGGASAANMRAQFDQCRQRLKLDQVDLLYLHRFDPETPLEDTLTCFAELKQEGHIR
HVGLSNFAAWQVMKAVALAARLGLRIDVLQPMYSLVKRQAEVEILPMCADQGILPVPYSPLGGGLLTGKYAQGGTGRLSE
DENYRARYGQDWMHRTASDLLHLAEDLGTDPATLAVAWAAGHPARPAPILSARSATQLAPSLKATEFDMSPELYARIEAL
SPRPAPATDRLEEA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI223718702, Length=196, Percent_Identity=40.3061224489796, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI41152114, Length=263, Percent_Identity=34.2205323193916, Blast_Score=118, Evalue=7e-27,
Organism=Homo sapiens, GI41327764, Length=226, Percent_Identity=37.6106194690265, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI27436964, Length=348, Percent_Identity=27.0114942528736, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI27436969, Length=305, Percent_Identity=25.9016393442623, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI4504825, Length=305, Percent_Identity=25.9016393442623, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI27436962, Length=286, Percent_Identity=27.2727272727273, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI27436966, Length=311, Percent_Identity=26.6881028938907, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI223718708, Length=162, Percent_Identity=37.037037037037, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI27436971, Length=302, Percent_Identity=26.158940397351, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI87081735, Length=309, Percent_Identity=32.6860841423948, Blast_Score=147, Evalue=9e-37,
Organism=Escherichia coli, GI1789199, Length=336, Percent_Identity=28.5714285714286, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1789375, Length=259, Percent_Identity=28.1853281853282, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788070, Length=316, Percent_Identity=28.4810126582279, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787674, Length=313, Percent_Identity=24.9201277955272, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788081, Length=158, Percent_Identity=30.379746835443, Blast_Score=65, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=319, Percent_Identity=23.5109717868339, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6323998, Length=334, Percent_Identity=26.3473053892216, Blast_Score=96, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6319958, Length=299, Percent_Identity=25.4180602006689, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6322615, Length=207, Percent_Identity=26.0869565217391, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6319951, Length=288, Percent_Identity=24.3055555555556, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36511; Mature: 36511

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00062 ALDOKETO_REDUCTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRPNSALRAPGLRVSLRRMTAQTCPPLTTLDGHDVGRFAFGCMQFGGRADAQASAEMYE
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHH
ACRAAGLRHFDTAWLYTEGASEEILGQLIAKDRESLYVATKVGFTGGASAANMRAQFDQC
HHHHCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHH
RQRLKLDQVDLLYLHRFDPETPLEDTLTCFAELKQEGHIRHVGLSNFAAWQVMKAVALAA
HHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHH
RLGLRIDVLQPMYSLVKRQAEVEILPMCADQGILPVPYSPLGGGLLTGKYAQGGTGRLSE
HHCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCCCC
DENYRARYGQDWMHRTASDLLHLAEDLGTDPATLAVAWAAGHPARPAPILSARSATQLAP
CCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHEEEEEECCCCCCCCCCCCCCCHHHHCC
SLKATEFDMSPELYARIEALSPRPAPATDRLEEA
CCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHCCC
>Mature Secondary Structure
MIRPNSALRAPGLRVSLRRMTAQTCPPLTTLDGHDVGRFAFGCMQFGGRADAQASAEMYE
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHH
ACRAAGLRHFDTAWLYTEGASEEILGQLIAKDRESLYVATKVGFTGGASAANMRAQFDQC
HHHHCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHH
RQRLKLDQVDLLYLHRFDPETPLEDTLTCFAELKQEGHIRHVGLSNFAAWQVMKAVALAA
HHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHH
RLGLRIDVLQPMYSLVKRQAEVEILPMCADQGILPVPYSPLGGGLLTGKYAQGGTGRLSE
HHCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCCCC
DENYRARYGQDWMHRTASDLLHLAEDLGTDPATLAVAWAAGHPARPAPILSARSATQLAP
CCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHEEEEEECCCCCCCCCCCCCCCHHHHCC
SLKATEFDMSPELYARIEALSPRPAPATDRLEEA
CCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]