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The map label for this gene is yxeN [H]

Identifier: 99080305

GI number: 99080305

Start: 482295

End: 483101

Strand: Direct

Name: yxeN [H]

Synonym: TM1040_0464

Alternate gene names: 99080305

Gene position: 482295-483101 (Clockwise)

Preceding gene: 99080304

Following gene: 99080306

Centisome position: 15.07

GC content: 60.22

Gene sequence:

>807_bases
ATGACCAATCGCCACAAGCGCGAAGACAAAGAAGATTTCCCGTGGTGGCTGGTCGCAGTCGGACTGACCGCGCTCTATCT
GGGCATTGAGGTCGCACTGAGCGACGTCTACGCACAGATCATGAACACGCTGTGGCGGGGCGTTGGGATTACCATCTTCG
TCACGATTGTGAGCTTCTTCTCCGCCTCGGCTTTGGGTCTTGCGCTCGCACTCGGGGCAGAATCGCGTTGGCTGGTGCTG
CGGCAGGTCTGCCGCTTTTACGTCGAGGTGGTGCGCGGCGTGCCAATCATCGTGCTGTTGCTTTATGTGGCCTTTGTACT
GGCACCGGCGCTTGTGGATCTGCGCAACTGGCTTGGCGGTTTTCTCGGTCTTGAGGACATTCGCACCCGCAACTTCCCGC
TCCTGTGGCGCGCGATCGTGGCCCTTATGATCGCCTATTCGGCCTTCATTGCCGAAGTCTTCAGGGCCGGTCTGCAGTCG
GTACCCGACGGCCAGATCGAGGCGGCAAAGGCGCTCGGGCTCTCGGGTTGGAAGCGGTTTCGCTTTGTGGTGTTCCCGCA
GGCCATCCGCACGATCCTGCCGCCGCTTGGCAATGACTTTGTCGCGCTGGTCAAGGATTCCTCGCTGGTGTCCGTGCTGG
GCGTTCTGGACATCACGCAGCTGGGCAAGGTCACGGCCGCCAGCAACTTTCGCTATTTCGAGACCTACAACATGGTCGCG
CTCATCTATCTGGCGATGACGATTTCCCTGTCTTTGGCCCTGCGCGCATTGGAGCGGCACTTGCGCAGCAAGCAAGAGCA
TCGCTAG

Upstream 100 bases:

>100_bases
TTCCTCGACTACAAGATGGGCCAATAAGCGCCTTTCCTTCTGAACTCCAATACCGCCCCGGCCAAACACAGGCCGGGGTT
TGTCGTGACAGGGCAAGCAC

Downstream 100 bases:

>100_bases
GCAATCCGGGGTCTTAGGCCAGCGAAAACCGAAACACCGCAGACAGATTGCAGGTCCCCGGTGAAGGCGCTAGCGTCGGT
GCAAAGGAGACCTCATATGA

Product: amino acid ABC transporter permease

Products: ADP; phosphate; L-glutamine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MTNRHKREDKEDFPWWLVAVGLTALYLGIEVALSDVYAQIMNTLWRGVGITIFVTIVSFFSASALGLALALGAESRWLVL
RQVCRFYVEVVRGVPIIVLLLYVAFVLAPALVDLRNWLGGFLGLEDIRTRNFPLLWRAIVALMIAYSAFIAEVFRAGLQS
VPDGQIEAAKALGLSGWKRFRFVVFPQAIRTILPPLGNDFVALVKDSSLVSVLGVLDITQLGKVTAASNFRYFETYNMVA
LIYLAMTISLSLALRALERHLRSKQEHR

Sequences:

>Translated_268_residues
MTNRHKREDKEDFPWWLVAVGLTALYLGIEVALSDVYAQIMNTLWRGVGITIFVTIVSFFSASALGLALALGAESRWLVL
RQVCRFYVEVVRGVPIIVLLLYVAFVLAPALVDLRNWLGGFLGLEDIRTRNFPLLWRAIVALMIAYSAFIAEVFRAGLQS
VPDGQIEAAKALGLSGWKRFRFVVFPQAIRTILPPLGNDFVALVKDSSLVSVLGVLDITQLGKVTAASNFRYFETYNMVA
LIYLAMTISLSLALRALERHLRSKQEHR
>Mature_267_residues
TNRHKREDKEDFPWWLVAVGLTALYLGIEVALSDVYAQIMNTLWRGVGITIFVTIVSFFSASALGLALALGAESRWLVLR
QVCRFYVEVVRGVPIIVLLLYVAFVLAPALVDLRNWLGGFLGLEDIRTRNFPLLWRAIVALMIAYSAFIAEVFRAGLQSV
PDGQIEAAKALGLSGWKRFRFVVFPQAIRTILPPLGNDFVALVKDSSLVSVLGVLDITQLGKVTAASNFRYFETYNMVAL
IYLAMTISLSLALRALERHLRSKQEHR

Specific function: Probably part of the ABC transporter complex yxeMNO that could be involved in amino-acid import. May transport S- methylcysteine. Probably responsible for the translocation of the substrate across the membrane (Probable) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787030, Length=217, Percent_Identity=34.5622119815668, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI87082239, Length=254, Percent_Identity=31.1023622047244, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788226, Length=226, Percent_Identity=30.5309734513274, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788646, Length=219, Percent_Identity=31.0502283105023, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI48994930, Length=131, Percent_Identity=39.6946564885496, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787087, Length=227, Percent_Identity=30.3964757709251, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788645, Length=228, Percent_Identity=27.1929824561404, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786873, Length=214, Percent_Identity=28.5046728971963, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1786874, Length=220, Percent_Identity=28.1818181818182, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29990; Mature: 29859

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNRHKREDKEDFPWWLVAVGLTALYLGIEVALSDVYAQIMNTLWRGVGITIFVTIVSFF
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SASALGLALALGAESRWLVLRQVCRFYVEVVRGVPIIVLLLYVAFVLAPALVDLRNWLGG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLGLEDIRTRNFPLLWRAIVALMIAYSAFIAEVFRAGLQSVPDGQIEAAKALGLSGWKRF
HHCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCHHHHHHH
RFVVFPQAIRTILPPLGNDFVALVKDSSLVSVLGVLDITQLGKVTAASNFRYFETYNMVA
HHEECHHHHHHHCCCCCCCCEEHCCCCHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHH
LIYLAMTISLSLALRALERHLRSKQEHR
HHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TNRHKREDKEDFPWWLVAVGLTALYLGIEVALSDVYAQIMNTLWRGVGITIFVTIVSFF
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SASALGLALALGAESRWLVLRQVCRFYVEVVRGVPIIVLLLYVAFVLAPALVDLRNWLGG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLGLEDIRTRNFPLLWRAIVALMIAYSAFIAEVFRAGLQSVPDGQIEAAKALGLSGWKRF
HHCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCHHHHHHH
RFVVFPQAIRTILPPLGNDFVALVKDSSLVSVLGVLDITQLGKVTAASNFRYFETYNMVA
HHEECHHHHHHHCCCCCCCCEEHCCCCHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHH
LIYLAMTISLSLALRALERHLRSKQEHR
HHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamine [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamine [Periplasm] + H2O = ADP + phosphate + L-glutamine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8867804; 9384377 [H]