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The map label for this gene is mcpA [H]

Identifier: 99080274

GI number: 99080274

Start: 445657

End: 447987

Strand: Reverse

Name: mcpA [H]

Synonym: TM1040_0433

Alternate gene names: 99080274

Gene position: 447987-445657 (Counterclockwise)

Preceding gene: 99080275

Following gene: 99080273

Centisome position: 14.0

GC content: 59.67

Gene sequence:

>2331_bases
GTGAGAACATTACCGAAATGCGCATGTATGACCCTCAAGGAGACCACCCCTGTGTTGCTAAAGCCATCGAGCGTTTCGCT
CAAACTCAAACTGCCCGTCTTGATGGTTGCCCTCACAGTTGCATTTGTGGTGACCGTATCTTTGCTCATCTACACGATGG
CCGAACGCAGCATCCACGAGAAGGTCGCTTCTGCAAAAGAATCCAAAGCGCACGCCGGCGCGCAGGCCCTGCGTTTCAGC
ATCGATGCTGCGCAACGCGATGTCTCCAACCTCGCAGCACTGCCAACCACCTTTCGCGCCATCAATAATTTCGAGCGCGT
CATCGGGATGATCGAGGTCGACGACAAGATCGGCTTCCTTAAAACGCACTACATCGTAGAGAACCCCAACACCGAAGAAG
AGCGCGCTGCACTGGTCGATCCCGGTGATGGCTCCTACTACAGCCAATCGCATGTGACGTATCATCCGACCTTTGTGCAG
ACTGCCGAACTCAGTGGATATTCAGACATATACCTGATCACCCCCGCGGGGCTTGTGGCCTATTCGGTCCACAAAAAAGG
GGACTTTGCGGAAAATATCAATGACAGCGTGCTGGCCGACACTGCCTTGTCGCGCGTCGCGCAAGCCGCTCTCGCGGCGG
AGCCCGGCAGCGTCGTCGTCGAAGATTTCTCAGCCTATGGGCCCTCCGGCGCCGTTGATGCGTTTCTTGCCTCTCCGATC
CTGAACAAGCGTGGCGATCCGGTGGGCGTGATAGCAGTACGGATTGGAACGGATTTTGTGCAATCTGCCCTGAACGCAAA
CCTCGCGGACGATGGCTATGAGAACATCTTTCTTGTCGACCCGGATGGCCGCACCAAGAGCCCGGGGATGATCGCCGGTG
CCTTCTCTCTCCTGAGCGTTCTTCCCGATGCCCCCCATATCGCCGCGGCACGCGCAGGCGAAGCCGGTAATTTCACCGCT
ACGGTCACCGCATTGGGCACACCCGCAACCGCCGTTGTGGTGCCGCTTGACCTCAATGGCTTTGACTGGTCGGTGGTGAT
GGAAACCGACAGCGCCCAGGCCTTTGCCGTGATCTATCGAATCCGCTGGATGGTGCTGTCCCTGATCGGCGCGTCGATCG
TTGTCTCCATCGGGGTTTCCTGGGCGGCTGCCAACAGGGTTACACGCCCGATCCATCAGCTGCGCGACGCCACCAATGCG
CTCGCGCAAGAGGACTACGACATTGCCATTTCCGGTCTCAGCCGTGGCGACGAATTTGGCGATCTGGCGCGCAGCCTCGA
TACCTTCCGCGACAAGCTCAAGAGCGCGGATGAGGCTGCAGAGCGCGAAGAGGAAGCCAAACGCGAAACAGATTTTGTGG
TGGATGAAATGAGCCGCGCCTTGGCGCAGCTGCAGGATGGCAATCTCGTGAGCGAGATTGAACACCCCTTCTCCGAAGAC
TACGAGACCCTACGCGAGAACTACAACCACAGCCTGCAGAACCTGCGCAACTCCCTGCGGGAAGTCGTGGAAGCCTCGCA
GCATGTGGATCGCTTCTCGCAGGAGCAGCGCGCCGCCGCCAACGAAATGGCCGAACGCACCGAGAGCCAGGGTTCCACGC
TTGAGAAAACTGCCACAGCCATGCAGGACCTGAGCCAGCGCCTTCGCGAAACAGCGGAAAAGGCCACCGAGGTCGACAGC
ACCATGCGTGGCACGCGCCGCGAGGCAGAACAGAGCAACGAGGTGGTGCGCTCTGCCGTGGCCGCCATGGATCAGATCCA
GCAGGCCTCCAGCGAAATTGCCAAATTCATCAATATGATTGATGATATCGCCTTCCAGACCAACCTCCTCGCTCTCAACG
CCGGAGTGGAGGCCGCACGGGCCGGGGAAGCAGGTGCAGGGTTCGCCGTTGTGGCCTCTGAGGTGCGAAACCTTGCGCGC
CGCGCTTCTGAAGCCGCCGGCGAGATCAAGACCCTGACCTCCGCAAGCGAGGAGCATGTCGCCAACGGGGTGTCGATGGT
GGACAAGGCGGGCAATGCGCTGACGAGCATTATCGCTCAGGTCTCCTCGGTGGGCGATCTTGTCTCTGAAATCGCGGGCG
GTGTTCAGCATCAGTCGCAGGGACTTGAAGACATCAACACCGCTATGCGCGAACTCGATGCCGTCACCCAGCAGAATACC
GCGATGGCCGAAGAAGCATCCGCGTCGAGTCAGTTGCTGCAAAGCGAAGCGCGCACGCTCTCCAGCGTCACCGGACGCTT
TCAGATTGATCCCCCCATGAGCACAGATGCACCCGCCTCTTGGGACGACGGCTCCGACACACCTGCCGCTTCACATGAGG
CAGCGGGCTAG

Upstream 100 bases:

>100_bases
CGACGCAAACACGCTGCATGCGATGGCACCGCAACAAAGCTTGAGTCAAGCAACCGCGAACAGCCGCGAGATCGTCGCAA
TACTGAATCTTAGGAAAGTT

Downstream 100 bases:

>100_bases
ACGCCAACGCAGCACTACAAGGTCAAACGCAAGGCCGCACCTTCGAAGGTGCGGCCTTGCGTTTTTATGTAAAACAGGGG
ATCAGCCTCTAAGAAAGCTC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 776; Mature: 776

Protein sequence:

>776_residues
MRTLPKCACMTLKETTPVLLKPSSVSLKLKLPVLMVALTVAFVVTVSLLIYTMAERSIHEKVASAKESKAHAGAQALRFS
IDAAQRDVSNLAALPTTFRAINNFERVIGMIEVDDKIGFLKTHYIVENPNTEEERAALVDPGDGSYYSQSHVTYHPTFVQ
TAELSGYSDIYLITPAGLVAYSVHKKGDFAENINDSVLADTALSRVAQAALAAEPGSVVVEDFSAYGPSGAVDAFLASPI
LNKRGDPVGVIAVRIGTDFVQSALNANLADDGYENIFLVDPDGRTKSPGMIAGAFSLLSVLPDAPHIAAARAGEAGNFTA
TVTALGTPATAVVVPLDLNGFDWSVVMETDSAQAFAVIYRIRWMVLSLIGASIVVSIGVSWAAANRVTRPIHQLRDATNA
LAQEDYDIAISGLSRGDEFGDLARSLDTFRDKLKSADEAAEREEEAKRETDFVVDEMSRALAQLQDGNLVSEIEHPFSED
YETLRENYNHSLQNLRNSLREVVEASQHVDRFSQEQRAAANEMAERTESQGSTLEKTATAMQDLSQRLRETAEKATEVDS
TMRGTRREAEQSNEVVRSAVAAMDQIQQASSEIAKFINMIDDIAFQTNLLALNAGVEAARAGEAGAGFAVVASEVRNLAR
RASEAAGEIKTLTSASEEHVANGVSMVDKAGNALTSIIAQVSSVGDLVSEIAGGVQHQSQGLEDINTAMRELDAVTQQNT
AMAEEASASSQLLQSEARTLSSVTGRFQIDPPMSTDAPASWDDGSDTPAASHEAAG

Sequences:

>Translated_776_residues
MRTLPKCACMTLKETTPVLLKPSSVSLKLKLPVLMVALTVAFVVTVSLLIYTMAERSIHEKVASAKESKAHAGAQALRFS
IDAAQRDVSNLAALPTTFRAINNFERVIGMIEVDDKIGFLKTHYIVENPNTEEERAALVDPGDGSYYSQSHVTYHPTFVQ
TAELSGYSDIYLITPAGLVAYSVHKKGDFAENINDSVLADTALSRVAQAALAAEPGSVVVEDFSAYGPSGAVDAFLASPI
LNKRGDPVGVIAVRIGTDFVQSALNANLADDGYENIFLVDPDGRTKSPGMIAGAFSLLSVLPDAPHIAAARAGEAGNFTA
TVTALGTPATAVVVPLDLNGFDWSVVMETDSAQAFAVIYRIRWMVLSLIGASIVVSIGVSWAAANRVTRPIHQLRDATNA
LAQEDYDIAISGLSRGDEFGDLARSLDTFRDKLKSADEAAEREEEAKRETDFVVDEMSRALAQLQDGNLVSEIEHPFSED
YETLRENYNHSLQNLRNSLREVVEASQHVDRFSQEQRAAANEMAERTESQGSTLEKTATAMQDLSQRLRETAEKATEVDS
TMRGTRREAEQSNEVVRSAVAAMDQIQQASSEIAKFINMIDDIAFQTNLLALNAGVEAARAGEAGAGFAVVASEVRNLAR
RASEAAGEIKTLTSASEEHVANGVSMVDKAGNALTSIIAQVSSVGDLVSEIAGGVQHQSQGLEDINTAMRELDAVTQQNT
AMAEEASASSQLLQSEARTLSSVTGRFQIDPPMSTDAPASWDDGSDTPAASHEAAG
>Mature_776_residues
MRTLPKCACMTLKETTPVLLKPSSVSLKLKLPVLMVALTVAFVVTVSLLIYTMAERSIHEKVASAKESKAHAGAQALRFS
IDAAQRDVSNLAALPTTFRAINNFERVIGMIEVDDKIGFLKTHYIVENPNTEEERAALVDPGDGSYYSQSHVTYHPTFVQ
TAELSGYSDIYLITPAGLVAYSVHKKGDFAENINDSVLADTALSRVAQAALAAEPGSVVVEDFSAYGPSGAVDAFLASPI
LNKRGDPVGVIAVRIGTDFVQSALNANLADDGYENIFLVDPDGRTKSPGMIAGAFSLLSVLPDAPHIAAARAGEAGNFTA
TVTALGTPATAVVVPLDLNGFDWSVVMETDSAQAFAVIYRIRWMVLSLIGASIVVSIGVSWAAANRVTRPIHQLRDATNA
LAQEDYDIAISGLSRGDEFGDLARSLDTFRDKLKSADEAAEREEEAKRETDFVVDEMSRALAQLQDGNLVSEIEHPFSED
YETLRENYNHSLQNLRNSLREVVEASQHVDRFSQEQRAAANEMAERTESQGSTLEKTATAMQDLSQRLRETAEKATEVDS
TMRGTRREAEQSNEVVRSAVAAMDQIQQASSEIAKFINMIDDIAFQTNLLALNAGVEAARAGEAGAGFAVVASEVRNLAR
RASEAAGEIKTLTSASEEHVANGVSMVDKAGNALTSIIAQVSSVGDLVSEIAGGVQHQSQGLEDINTAMRELDAVTQQNT
AMAEEASASSQLLQSEARTLSSVTGRFQIDPPMSTDAPASWDDGSDTPAASHEAAG

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=300, Percent_Identity=36.3333333333333, Blast_Score=166, Evalue=6e-42,
Organism=Escherichia coli, GI2367378, Length=253, Percent_Identity=39.9209486166008, Blast_Score=166, Evalue=6e-42,
Organism=Escherichia coli, GI1788194, Length=258, Percent_Identity=38.3720930232558, Blast_Score=163, Evalue=5e-41,
Organism=Escherichia coli, GI1787690, Length=280, Percent_Identity=36.0714285714286, Blast_Score=153, Evalue=3e-38,
Organism=Escherichia coli, GI1789453, Length=220, Percent_Identity=36.3636363636364, Blast_Score=142, Evalue=8e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 82977; Mature: 82977

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTLPKCACMTLKETTPVLLKPSSVSLKLKLPVLMVALTVAFVVTVSLLIYTMAERSIHE
CCCCCHHHHHHHCCCCCEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVASAKESKAHAGAQALRFSIDAAQRDVSNLAALPTTFRAINNFERVIGMIEVDDKIGFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEE
KTHYIVENPNTEEERAALVDPGDGSYYSQSHVTYHPTFVQTAELSGYSDIYLITPAGLVA
EEEEEEECCCCHHHCEEEECCCCCCCCCCCCCEECCCCEEECCCCCCCCEEEECCCCHHH
YSVHKKGDFAENINDSVLADTALSRVAQAALAAEPGSVVVEDFSAYGPSGAVDAFLASPI
EEHHCCCCCHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHCCCCCCHHHHHHHHHH
LNKRGDPVGVIAVRIGTDFVQSALNANLADDGYENIFLVDPDGRTKSPGMIAGAFSLLSV
HHCCCCCEEEEEEEECHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
LPDAPHIAAARAGEAGNFTATVTALGTPATAVVVPLDLNGFDWSVVMETDSAQAFAVIYR
CCCCCCHHHHCCCCCCCCEEEEEECCCCCEEEEEEEECCCCCEEEEEECCCCHHHHHHHH
IRWMVLSLIGASIVVSIGVSWAAANRVTRPIHQLRDATNALAQEDYDIAISGLSRGDEFG
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHH
DLARSLDTFRDKLKSADEAAEREEEAKRETDFVVDEMSRALAQLQDGNLVSEIEHPFSED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHH
YETLRENYNHSLQNLRNSLREVVEASQHVDRFSQEQRAAANEMAERTESQGSTLEKTATA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
MQDLSQRLRETAEKATEVDSTMRGTRREAEQSNEVVRSAVAAMDQIQQASSEIAKFINMI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DDIAFQTNLLALNAGVEAARAGEAGAGFAVVASEVRNLARRASEAAGEIKTLTSASEEHV
HHHHHHHCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
ANGVSMVDKAGNALTSIIAQVSSVGDLVSEIAGGVQHQSQGLEDINTAMRELDAVTQQNT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHH
AMAEEASASSQLLQSEARTLSSVTGRFQIDPPMSTDAPASWDDGSDTPAASHEAAG
HHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRTLPKCACMTLKETTPVLLKPSSVSLKLKLPVLMVALTVAFVVTVSLLIYTMAERSIHE
CCCCCHHHHHHHCCCCCEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVASAKESKAHAGAQALRFSIDAAQRDVSNLAALPTTFRAINNFERVIGMIEVDDKIGFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEE
KTHYIVENPNTEEERAALVDPGDGSYYSQSHVTYHPTFVQTAELSGYSDIYLITPAGLVA
EEEEEEECCCCHHHCEEEECCCCCCCCCCCCCEECCCCEEECCCCCCCCEEEECCCCHHH
YSVHKKGDFAENINDSVLADTALSRVAQAALAAEPGSVVVEDFSAYGPSGAVDAFLASPI
EEHHCCCCCHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHCCCCCCHHHHHHHHHH
LNKRGDPVGVIAVRIGTDFVQSALNANLADDGYENIFLVDPDGRTKSPGMIAGAFSLLSV
HHCCCCCEEEEEEEECHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
LPDAPHIAAARAGEAGNFTATVTALGTPATAVVVPLDLNGFDWSVVMETDSAQAFAVIYR
CCCCCCHHHHCCCCCCCCEEEEEECCCCCEEEEEEEECCCCCEEEEEECCCCHHHHHHHH
IRWMVLSLIGASIVVSIGVSWAAANRVTRPIHQLRDATNALAQEDYDIAISGLSRGDEFG
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHH
DLARSLDTFRDKLKSADEAAEREEEAKRETDFVVDEMSRALAQLQDGNLVSEIEHPFSED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHH
YETLRENYNHSLQNLRNSLREVVEASQHVDRFSQEQRAAANEMAERTESQGSTLEKTATA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
MQDLSQRLRETAEKATEVDSTMRGTRREAEQSNEVVRSAVAAMDQIQQASSEIAKFINMI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DDIAFQTNLLALNAGVEAARAGEAGAGFAVVASEVRNLARRASEAAGEIKTLTSASEEHV
HHHHHHHCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
ANGVSMVDKAGNALTSIIAQVSSVGDLVSEIAGGVQHQSQGLEDINTAMRELDAVTQQNT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHH
AMAEEASASSQLLQSEARTLSSVTGRFQIDPPMSTDAPASWDDGSDTPAASHEAAG
HHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]