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The map label for this gene is glk [H]

Identifier: 99080204

GI number: 99080204

Start: 372959

End: 373921

Strand: Direct

Name: glk [H]

Synonym: TM1040_0363

Alternate gene names: 99080204

Gene position: 372959-373921 (Clockwise)

Preceding gene: 99080203

Following gene: 99080205

Centisome position: 11.65

GC content: 65.32

Gene sequence:

>963_bases
ATGTGGAATCTGATCGCTGACGTCGGCGGAACAAACATGCGGCTGGCGGCCGTGAATGCGGAGGGGGAGATCCTCGAGCA
AGCCCGGTATGACAGCAAGGGCACGCAGAACCTTGAAGAGGCCTGTGCAGATTTTGCAGCCCATCGCGGCAGCGCGCCTG
GCCGTGCCGTCATTGCGGCGGCAGGTGTGGTGCGGGGCGGCTCCGTTCAGTTGACCAACGCCAACCAGAGTTTTTCCGAA
CGCGGGATTGCCGTAGCCCTGCAAACCGAGCGGGTCAAAGTTCTGAATGACTTTGAAGCCGCTGCCTGGTCACTGGCTTC
GGTGAGTGCGGGGGATGTGACCGTGCTGCAGGGGCAGGCGGTGTTTCCCAAGGAACCCTGTCTGATCATCGGCCCGGGCA
CCGGGCTTGGCGTGGGGGCCCTGATTTGGGCCAATGGCGAACCCTGCGTTGTCCCCGGCGAAGGGGGGCATGTTGCCATC
GGCCCGCGCACGGCCGATGAGGTCGCGATCTTTGAGGCGTTGCGCGAGGAATGGCCCGAGATCGGCATGGGGCCGGGGCT
TGCGGTAGAGGCCGAAGGCATCCTCTCGGGCACAGGGTTGCCTTACTTTTACCGCGCGGTTGCGCGCAGCATGGAGCTGA
CCGCGCCGCTCACGACTGGGGCGGAGATTTTTCAGTCCGCGCAGGCCCGGCTCGACACCGCAGCGGTGCGTGCGGTGTCG
CTCTTTGCGCAGTATCTCGCCGGAGTCGCGGGGGATCTCGGTCTCGTCTTCGCGGCCAAAGGGGGCGTGTTCGTCACCGG
GGGCGTTGCCGCCGCAAACCCGTGGATCTTTGATGCGGCCTTTGTGGAGGCGTTCAACGCGGGTGGGCGCCACACCGCGT
GGCGCGAAGAGCTGCCGCTGCATCTCTATCATCAGCCCAATTTCGGCCTGATCGGCGCGCGCAATTATCTGCGCGCCCGC
TGA

Upstream 100 bases:

>100_bases
TTGACCCGCGCGCGCTGAGCCTGTTTGACCCATGGCAACTGACAACCTGAGCATCGGCTTTGCCCGCGCCTGTTTGGTGT
GGCGAACTGGAGGGGCTAAG

Downstream 100 bases:

>100_bases
GATCGATGCGCCGTATTTGAGCCGCATCATCCAGCGCGCCCTGGCGTGTGTCCGGCCAGTCTCATCTTGATATTCCAACA
CAGAAGGCCAAGCATTGCAG

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MWNLIADVGGTNMRLAAVNAEGEILEQARYDSKGTQNLEEACADFAAHRGSAPGRAVIAAAGVVRGGSVQLTNANQSFSE
RGIAVALQTERVKVLNDFEAAAWSLASVSAGDVTVLQGQAVFPKEPCLIIGPGTGLGVGALIWANGEPCVVPGEGGHVAI
GPRTADEVAIFEALREEWPEIGMGPGLAVEAEGILSGTGLPYFYRAVARSMELTAPLTTGAEIFQSAQARLDTAAVRAVS
LFAQYLAGVAGDLGLVFAAKGGVFVTGGVAAANPWIFDAAFVEAFNAGGRHTAWREELPLHLYHQPNFGLIGARNYLRAR

Sequences:

>Translated_320_residues
MWNLIADVGGTNMRLAAVNAEGEILEQARYDSKGTQNLEEACADFAAHRGSAPGRAVIAAAGVVRGGSVQLTNANQSFSE
RGIAVALQTERVKVLNDFEAAAWSLASVSAGDVTVLQGQAVFPKEPCLIIGPGTGLGVGALIWANGEPCVVPGEGGHVAI
GPRTADEVAIFEALREEWPEIGMGPGLAVEAEGILSGTGLPYFYRAVARSMELTAPLTTGAEIFQSAQARLDTAAVRAVS
LFAQYLAGVAGDLGLVFAAKGGVFVTGGVAAANPWIFDAAFVEAFNAGGRHTAWREELPLHLYHQPNFGLIGARNYLRAR
>Mature_320_residues
MWNLIADVGGTNMRLAAVNAEGEILEQARYDSKGTQNLEEACADFAAHRGSAPGRAVIAAAGVVRGGSVQLTNANQSFSE
RGIAVALQTERVKVLNDFEAAAWSLASVSAGDVTVLQGQAVFPKEPCLIIGPGTGLGVGALIWANGEPCVVPGEGGHVAI
GPRTADEVAIFEALREEWPEIGMGPGLAVEAEGILSGTGLPYFYRAVARSMELTAPLTTGAEIFQSAQARLDTAAVRAVS
LFAQYLAGVAGDLGLVFAAKGGVFVTGGVAAANPWIFDAAFVEAFNAGGRHTAWREELPLHLYHQPNFGLIGARNYLRAR

Specific function: Not Highly Important In E.Coli As Glucose Is Transported Into The Cell By The Pts System Already As Glucose 6-Phosphate. [C]

COG id: COG0837

COG function: function code G; Glucokinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial glucokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788732, Length=319, Percent_Identity=31.6614420062696, Blast_Score=135, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003836 [H]

Pfam domain/function: PF02685 Glucokinase [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 33343; Mature: 33343

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWNLIADVGGTNMRLAAVNAEGEILEQARYDSKGTQNLEEACADFAAHRGSAPGRAVIAA
CCEEEEECCCCCEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEE
AGVVRGGSVQLTNANQSFSERGIAVALQTERVKVLNDFEAAAWSLASVSAGDVTVLQGQA
CCEEECCEEEEECCCCCHHHCCEEEEEECCCEEHHHHHHHHHHHHHCCCCCCEEEEECCC
VFPKEPCLIIGPGTGLGVGALIWANGEPCVVPGEGGHVAIGPRTADEVAIFEALREEWPE
CCCCCCEEEEECCCCCCCEEEEEECCCEEEEECCCCEEEECCCCHHHHHHHHHHHHHCCC
IGMGPGLAVEAEGILSGTGLPYFYRAVARSMELTAPLTTGAEIFQSAQARLDTAAVRAVS
CCCCCCCEEEECCEECCCCCHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHH
LFAQYLAGVAGDLGLVFAAKGGVFVTGGVAAANPWIFDAAFVEAFNAGGRHTAWREELPL
HHHHHHHHHCCCCEEEEEECCCEEEECCCCCCCCCEEHHHHHHHHCCCCCCCCHHHCCCE
HLYHQPNFGLIGARNYLRAR
EEEECCCCCEEECCHHHCCC
>Mature Secondary Structure
MWNLIADVGGTNMRLAAVNAEGEILEQARYDSKGTQNLEEACADFAAHRGSAPGRAVIAA
CCEEEEECCCCCEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEE
AGVVRGGSVQLTNANQSFSERGIAVALQTERVKVLNDFEAAAWSLASVSAGDVTVLQGQA
CCEEECCEEEEECCCCCHHHCCEEEEEECCCEEHHHHHHHHHHHHHCCCCCCEEEEECCC
VFPKEPCLIIGPGTGLGVGALIWANGEPCVVPGEGGHVAIGPRTADEVAIFEALREEWPE
CCCCCCEEEEECCCCCCCEEEEEECCCEEEEECCCCEEEECCCCHHHHHHHHHHHHHCCC
IGMGPGLAVEAEGILSGTGLPYFYRAVARSMELTAPLTTGAEIFQSAQARLDTAAVRAVS
CCCCCCCEEEECCEECCCCCHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHH
LFAQYLAGVAGDLGLVFAAKGGVFVTGGVAAANPWIFDAAFVEAFNAGGRHTAWREELPL
HHHHHHHHHCCCCEEEEEECCCEEEECCCCCCCCCEEHHHHHHHHCCCCCCCCHHHCCCE
HLYHQPNFGLIGARNYLRAR
EEEECCCCCEEECCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]