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The map label for this gene is aroQ

Identifier: 99080178

GI number: 99080178

Start: 341517

End: 341957

Strand: Direct

Name: aroQ

Synonym: TM1040_0337

Alternate gene names: 99080178

Gene position: 341517-341957 (Clockwise)

Preceding gene: 99080175

Following gene: 99080179

Centisome position: 10.67

GC content: 60.54

Gene sequence:

>441_bases
ATGACCCAAACCGTCTACATTCTCAATGGGCCCAACCTGAACCTTCTGGGCACCCGCGAGCCCGAGATCTATGGGCGCGA
AACGCTGGCCGACATCGAGGCGCGGTGTCGCACGCTGTGCGAGGGGCACGGGTTTGAGCTTATGTTCCTGCAGTCCAACC
ACGAGGGCCAGCTTGTCGACTGGATTCAGGAGGCCCGGACCTCGGCCTGCGGTATCATCATCAACCCCGCAGCCTATACG
CATACCTCTGTCGCCATTCGCGATGCGCTAAGTGCCTGCGAGATGCCGATCTTCGAGGTGCATCTGTCGAATGTACATGC
GCGCGAGGCCTTTCGGCACCATTCCTATGTGTCGGCGATTGCGACCGGGGTGATCGCGGGGTTTGGCTCTTTTGGCTATG
TCGCCGCGCTAGAGAAACTGGCGCAGGACGTTGGAGCCTGA

Upstream 100 bases:

>100_bases
CAGGCGATTGGCCCTTTTGAAGAAATCATGGCGCCAACCCCGTCGAATGTCGTATGAACGGGCGCGGCCGCACTGGTTCA
CGACATCTGAAGGACACCCG

Downstream 100 bases:

>100_bases
ACGCCCTACCCTCCTAACGGACGGAGGTGTGGCTGGTCTTCTCCCATAGCTGACGCGGGGTAGCACTGTCTGCGGGTGGC
CGCGGTTTTGCACCGGTTTT

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 146; Mature: 145

Protein sequence:

>146_residues
MTQTVYILNGPNLNLLGTREPEIYGRETLADIEARCRTLCEGHGFELMFLQSNHEGQLVDWIQEARTSACGIIINPAAYT
HTSVAIRDALSACEMPIFEVHLSNVHAREAFRHHSYVSAIATGVIAGFGSFGYVAALEKLAQDVGA

Sequences:

>Translated_146_residues
MTQTVYILNGPNLNLLGTREPEIYGRETLADIEARCRTLCEGHGFELMFLQSNHEGQLVDWIQEARTSACGIIINPAAYT
HTSVAIRDALSACEMPIFEVHLSNVHAREAFRHHSYVSAIATGVIAGFGSFGYVAALEKLAQDVGA
>Mature_145_residues
TQTVYILNGPNLNLLGTREPEIYGRETLADIEARCRTLCEGHGFELMFLQSNHEGQLVDWIQEARTSACGIIINPAAYTH
TSVAIRDALSACEMPIFEVHLSNVHAREAFRHHSYVSAIATGVIAGFGSFGYVAALEKLAQDVGA

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_SILST (Q1GJU6)

Other databases:

- EMBL:   CP000377
- RefSeq:   YP_612332.1
- ProteinModelPortal:   Q1GJU6
- SMR:   Q1GJU6
- STRING:   Q1GJU6
- GeneID:   4076038
- GenomeReviews:   CP000377_GR
- KEGG:   sit:TM1040_0337
- NMPDR:   fig|292414.1.peg.2482
- eggNOG:   COG0757
- HOGENOM:   HBG284657
- OMA:   EFRQTNH
- ProtClustDB:   PRK05395
- BioCyc:   SSP292414:TM1040_0337-MONOMER
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 15949; Mature: 15818

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 24-24 ACT_SITE 101-101 BINDING 75-75 BINDING 81-81 BINDING 88-88 BINDING 112-112

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTVYILNGPNLNLLGTREPEIYGRETLADIEARCRTLCEGHGFELMFLQSNHEGQLVD
CCEEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHH
WIQEARTSACGIIINPAAYTHTSVAIRDALSACEMPIFEVHLSNVHAREAFRHHSYVSAI
HHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHH
ATGVIAGFGSFGYVAALEKLAQDVGA
HHHHHHHCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TQTVYILNGPNLNLLGTREPEIYGRETLADIEARCRTLCEGHGFELMFLQSNHEGQLVD
CEEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHH
WIQEARTSACGIIINPAAYTHTSVAIRDALSACEMPIFEVHLSNVHAREAFRHHSYVSAI
HHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHH
ATGVIAGFGSFGYVAALEKLAQDVGA
HHHHHHHCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA