Click here to switch to the map view.

The map label for this gene is rsbS [H]

Identifier: 99079981

GI number: 99079981

Start: 153323

End: 153679

Strand: Reverse

Name: rsbS [H]

Synonym: TM1040_0140

Alternate gene names: 99079981

Gene position: 153679-153323 (Counterclockwise)

Preceding gene: 99079982

Following gene: 99079980

Centisome position: 4.8

GC content: 54.9

Gene sequence:

>357_bases
ATGGCATTGCGTGTCCCGATCCTCAGTCAAGGAGAGTTGCTCATCGCCTCGATCCAGGAGGAGTTGTCAGATAGTGAGAT
CCTTGATCTGCAGGCCCGTATTCTGGATGAGGTCGCCGCCAAGAAGGCGCGAAACGTTATCGTCGATGTCAGCTTGCTTG
ACGTCCTCGATAGCTTTGGAACAAGAACACTGTCCGAAATCGCGGCAGCGGTCCGCTTGAGAGGAGCCCAAATGGTCATT
GTTGGCATTCAGCCCGAAGTGGCCATGGCCATGGTTCTCCTGGGCCTGTCGCTAGAAGGCGTGCCAACAGCACTTGATCT
CGACCATGGCATCGAACTTCTGAAAGCCAGACCATGA

Upstream 100 bases:

>100_bases
AATCCCTCGTGAAGCTCGGCGTCACCGGTGAAACCCTGAACCCAGCCGGCGACCTTCAGCGTGGGATCGAAACGGCAGAA
GCGCTTTTGGACGGCTAAAG

Downstream 100 bases:

>100_bases
ACGCCATTCTCACCGAAACTGACCTGGTTCAGTTGGAGATCGAGGATGATCGCGACGTGGTCACCGCGCGCAGCAATGGG
CGCAAGATGGCGGCTGAGAT

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbS [H]

Number of amino acids: Translated: 118; Mature: 117

Protein sequence:

>118_residues
MALRVPILSQGELLIASIQEELSDSEILDLQARILDEVAAKKARNVIVDVSLLDVLDSFGTRTLSEIAAAVRLRGAQMVI
VGIQPEVAMAMVLLGLSLEGVPTALDLDHGIELLKARP

Sequences:

>Translated_118_residues
MALRVPILSQGELLIASIQEELSDSEILDLQARILDEVAAKKARNVIVDVSLLDVLDSFGTRTLSEIAAAVRLRGAQMVI
VGIQPEVAMAMVLLGLSLEGVPTALDLDHGIELLKARP
>Mature_117_residues
ALRVPILSQGELLIASIQEELSDSEILDLQARILDEVAAKKARNVIVDVSLLDVLDSFGTRTLSEIAAAVRLRGAQMVIV
GIQPEVAMAMVLLGLSLEGVPTALDLDHGIELLKARP

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645 [H]

Pfam domain/function: PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 12623; Mature: 12492

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALRVPILSQGELLIASIQEELSDSEILDLQARILDEVAAKKARNVIVDVSLLDVLDSFG
CEEECCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHC
TRTLSEIAAAVRLRGAQMVIVGIQPEVAMAMVLLGLSLEGVPTALDLDHGIELLKARP
CHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCCCCCCEECHHHCHHHHCCCC
>Mature Secondary Structure 
ALRVPILSQGELLIASIQEELSDSEILDLQARILDEVAAKKARNVIVDVSLLDVLDSFG
EEECCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHC
TRTLSEIAAAVRLRGAQMVIVGIQPEVAMAMVLLGLSLEGVPTALDLDHGIELLKARP
CHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCCCCCCEECHHHCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 8824586; 8682789 [H]