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The map label for this gene is dppB [H]

Identifier: 99079878

GI number: 99079878

Start: 38430

End: 39488

Strand: Reverse

Name: dppB [H]

Synonym: TM1040_0037

Alternate gene names: 99079878

Gene position: 39488-38430 (Counterclockwise)

Preceding gene: 99079879

Following gene: 99079877

Centisome position: 1.23

GC content: 57.03

Gene sequence:

>1059_bases
ATGGCGTTTTACAGCAACGTCCCGAAGAGGCAGCCTTGGCTGCCTCTTCCCCCTTGGGCAAGAAGCATGGGGATCACCCT
GCTTTCCGTCTCAATCACCATGTTGGGGCTCTTGTTCGTCACCTTCCTGATCGGGCGCGTTATGCCTATTGACCCGGTTC
TGGCGGTGGTTGGCGAACGCGCCAGCGAAGAGCAATACAATGCGGTTTATCTGGAGCTTGGGCTCGATAAACAATTGATC
ATACAGTTTTTCTATTACGTCGGCGATGTCCTGCAAGGTGACTTTGGCAAATCGCTTCTGACCGCGCGCCCGGTGTCAGA
GGACATCGCCCGCGTGTTTCCTGCCACCTTTGAGCTTGCAACGATTGGCATTATCTTTGGCTGCGTCCTCGGGGTGCCGC
TAGGGGTCATCGCCGCGGTGCGCCGTGGCAGTTGGGTGGATCAGATCGCCCGCGTGGTGGCATTGGTGGGCTATTCGATG
CCGATCTTCTGGCTGGGCCTGATGGGGCTTTTGCTCTTTTACGGCATGCTCGGCTGGGTCGGCGGACCGGGGCGGCAGGG
CATCTTTTACGAGGACATGATCCCCTCCGTAACGGGCATGATCCTTGTGGATTCGATCATTGCAGGCGACTGGGGCGCCT
TCTGGGATGCGTTTTCACATATCATCCTGCCCGCCTCTCTGCTGGGATACTACTCCTTGGCCTACATCAGCCGCATGACG
CGTTCGTTCATGCTGGAACAGCTTTCGGCCGAGTACATCACCACAGCCCGCGTCAAAGGCATGAGCGAATGGGCGGTGGT
CATGAACCATGCATTCAAGAATATCCGCGTGCAGCTCATCACCGTGATCGCGCTCTCTTATGCGAACCTCCTCGAGGGAT
CGGTGCTGACGGAGATCATCTTTTCCTGGCCGGGGATCGGAAACTACATCACCACGGCATTGTTGTCGGCTGACATGAAC
GCCGTGCTTGGTGGCACCGTGGTCGTCGGCCTCGTGTTCATCGTGCTGAACGTTTTTTCCGACCTCCTCTACAAAGTCTT
TGATCCGAGGTCGAAATGA

Upstream 100 bases:

>100_bases
TTCCAGCTGGTTGAACAGGCTGGCATCAGCGAAAAGGTCGAGGGTCTGAACCTTGGTGGCGCGATCACCGCAGCCGCTTA
CTGGGACGTGACCAAGTAAG

Downstream 100 bases:

>100_bases
GCAGCCAGACCATGACACTTCGAGAGTGGCTCTTGACGGATACGCCAACGTCGCGCCGTCAGGCCAGGCTGGCCGCCTAT
TACAAAGGCTGGCTAACCTT

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MAFYSNVPKRQPWLPLPPWARSMGITLLSVSITMLGLLFVTFLIGRVMPIDPVLAVVGERASEEQYNAVYLELGLDKQLI
IQFFYYVGDVLQGDFGKSLLTARPVSEDIARVFPATFELATIGIIFGCVLGVPLGVIAAVRRGSWVDQIARVVALVGYSM
PIFWLGLMGLLLFYGMLGWVGGPGRQGIFYEDMIPSVTGMILVDSIIAGDWGAFWDAFSHIILPASLLGYYSLAYISRMT
RSFMLEQLSAEYITTARVKGMSEWAVVMNHAFKNIRVQLITVIALSYANLLEGSVLTEIIFSWPGIGNYITTALLSADMN
AVLGGTVVVGLVFIVLNVFSDLLYKVFDPRSK

Sequences:

>Translated_352_residues
MAFYSNVPKRQPWLPLPPWARSMGITLLSVSITMLGLLFVTFLIGRVMPIDPVLAVVGERASEEQYNAVYLELGLDKQLI
IQFFYYVGDVLQGDFGKSLLTARPVSEDIARVFPATFELATIGIIFGCVLGVPLGVIAAVRRGSWVDQIARVVALVGYSM
PIFWLGLMGLLLFYGMLGWVGGPGRQGIFYEDMIPSVTGMILVDSIIAGDWGAFWDAFSHIILPASLLGYYSLAYISRMT
RSFMLEQLSAEYITTARVKGMSEWAVVMNHAFKNIRVQLITVIALSYANLLEGSVLTEIIFSWPGIGNYITTALLSADMN
AVLGGTVVVGLVFIVLNVFSDLLYKVFDPRSK
>Mature_351_residues
AFYSNVPKRQPWLPLPPWARSMGITLLSVSITMLGLLFVTFLIGRVMPIDPVLAVVGERASEEQYNAVYLELGLDKQLII
QFFYYVGDVLQGDFGKSLLTARPVSEDIARVFPATFELATIGIIFGCVLGVPLGVIAAVRRGSWVDQIARVVALVGYSMP
IFWLGLMGLLLFYGMLGWVGGPGRQGIFYEDMIPSVTGMILVDSIIAGDWGAFWDAFSHIILPASLLGYYSLAYISRMTR
SFMLEQLSAEYITTARVKGMSEWAVVMNHAFKNIRVQLITVIALSYANLLEGSVLTEIIFSWPGIGNYITTALLSADMNA
VLGGTVVVGLVFIVLNVFSDLLYKVFDPRSK

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=323, Percent_Identity=43.343653250774, Blast_Score=246, Evalue=1e-66,
Organism=Escherichia coli, GI1787761, Length=315, Percent_Identity=41.5873015873016, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1787053, Length=310, Percent_Identity=32.258064516129, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1787550, Length=268, Percent_Identity=30.9701492537313, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1789888, Length=316, Percent_Identity=29.746835443038, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1787497, Length=322, Percent_Identity=27.3291925465839, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1788504, Length=280, Percent_Identity=27.1428571428571, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 38768; Mature: 38637

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFYSNVPKRQPWLPLPPWARSMGITLLSVSITMLGLLFVTFLIGRVMPIDPVLAVVGER
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
ASEEQYNAVYLELGLDKQLIIQFFYYVGDVLQGDFGKSLLTARPVSEDIARVFPATFELA
CCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHCCHHHHHH
TIGIIFGCVLGVPLGVIAAVRRGSWVDQIARVVALVGYSMPIFWLGLMGLLLFYGMLGWV
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
GGPGRQGIFYEDMIPSVTGMILVDSIIAGDWGAFWDAFSHIILPASLLGYYSLAYISRMT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSFMLEQLSAEYITTARVKGMSEWAVVMNHAFKNIRVQLITVIALSYANLLEGSVLTEII
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSWPGIGNYITTALLSADMNAVLGGTVVVGLVFIVLNVFSDLLYKVFDPRSK
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AFYSNVPKRQPWLPLPPWARSMGITLLSVSITMLGLLFVTFLIGRVMPIDPVLAVVGER
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
ASEEQYNAVYLELGLDKQLIIQFFYYVGDVLQGDFGKSLLTARPVSEDIARVFPATFELA
CCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHCCHHHHHH
TIGIIFGCVLGVPLGVIAAVRRGSWVDQIARVVALVGYSMPIFWLGLMGLLLFYGMLGWV
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
GGPGRQGIFYEDMIPSVTGMILVDSIIAGDWGAFWDAFSHIILPASLLGYYSLAYISRMT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSFMLEQLSAEYITTARVKGMSEWAVVMNHAFKNIRVQLITVIALSYANLLEGSVLTEII
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSWPGIGNYITTALLSADMNAVLGGTVVVGLVFIVLNVFSDLLYKVFDPRSK
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]